Adrenal oncocytic neoplasm: A systematic review

Urologia Internationalis

Volumn 91, Issue 2, 2013, Pages 125-133

  Mearini, Luigi ^a   Del Sordo, Rachele ^a   Costantini, Elisabetta ^a   Nunzi, Elisabetta ^a   Porena, Massimo ^a  

^a UNIVERSITY OF PERUGIA   (Italy)

Author keywords

Adrenal gland; Adrenal oncocytic neoplasm; Oncocytoma

Indexed keywords

(3 IODOBENZYL)GUANIDINE; ALPHA INHIBIN; CALRETININ; CHROMOGRANIN; COLLAGEN; CYTOKERATIN 18; CYTOKERATIN 8; CYTOKERATIN AE1; CYTOKERATIN AE3; FLUORODEOXYGLUCOSE F 18; INHIBIN; IODINE; KERATIN; LIPID; MELAN A; MITOCHONDRION ANTIBODY; MITOTANE; NITROSOMORPHOLINE; SYNAPTOPHYSIN; UNCLASSIFIED DRUG; VIMENTIN;

ADRENAL CORTEX ADENOMA; ADRENAL CORTEX CARCINOMA; ADRENAL INCIDENTALOMA; ADRENAL MEDULLA TUMOR; ADRENAL METASTASIS; ADRENAL ONCOCYTIC NEOPLASM; ADRENAL TUMOR; ADRENALECTOMY; CANCER CELL; CANCER CLASSIFICATION; CANCER DIAGNOSIS; CANCER INCIDENCE; CANCER MORPHOLOGY; CANCER PROGNOSIS; CANCER RADIOTHERAPY; CANCER SURGERY; CANCER SURVIVAL; COMPUTER ASSISTED TOMOGRAPHY; CYTOPLASM; DIFFERENTIAL DIAGNOSIS; ECHOGRAPHY; EOSINOPHIL; FINE NEEDLE ASPIRATION BIOPSY; HISTOPATHOLOGY; HUMAN; IMMUNOPHENOTYPING; IMMUNOREACTIVITY; LAPAROSCOPIC SURGERY; MITOCHONDRION; NEUROBLASTOMA; NEUROSECRETORY CELL; NUCLEAR MAGNETIC RESONANCE IMAGING; ONCOCYTOMA; PERCUTANEOUS BIOPSY; PHEOCHROMOCYTOMA; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RADIOFREQUENCY ABLATION; REVIEW; SMOOTH ENDOPLASMIC RETICULUM; SURVIVAL RATE; SYSTEMATIC REVIEW; THYROID PARAFOLLICULAR CELL; TUMOR VOLUME; HISTOLOGY; LAPAROSCOPY; META ANALYSIS; MULTIMODALITY CANCER THERAPY;

ADENOMA, OXYPHILIC; ADRENAL CORTEX NEOPLASMS; ANIMALS; CARCINOMA; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LAPAROSCOPY; MAGNETIC RESONANCE IMAGING; MALE; PROGNOSIS; SEX FACTORS; TOMOGRAPHY, X-RAY COMPUTED;

EID: 84883744360     PISSN: 00421138     EISSN: 14230399     Source Type: Journal    
DOI: 10.1159/000345141     Document Type: Review

References (98)

1. Chang A, Harawi SJ: Oncocytes, oncocytosis, and oncocytic tumors. Pathol Annu 1992; 27: 263-304.
2. Tallini G: Oncocytic tumours. Virchows Arch 1998; 1: 5-12.
3. Tsuta K, Kalhor N, Raso MG, Wistuba II, Moran CA: Oncocytic neuroendocrine tumors of the lung: histopathologic spectrum and immunohistochemical analysis of 15 cases. Hum Pathol 2011; 42: 578-585.
4. Kozakiewicz J, Teodorowicz E, Haczyńska-Partyka A, Myrcik G, Lange D, Szwabowicz M: Adenoma oxyphillicum, an extremely rare case of tumour of the larynx end cancer lungs which are going together. Otolaryngol Pol 2007; 61: 311-314.
5. Sav A, Scheithauer BW, Mazzola CA, Ketterling SR, Thompson SJ, Reilly MH: Oncocytic choroid plexus carcinoma: case report. Clin Neuropathol 2010; 29: 14-20.
6. Kakimoto S, Yushita Y, Sanefuji T, Kondo A, Fujishima N, Kishikawa M, Matsumoto K: Non-hormonal adrenocortical adenoma with oncocytoma-like appearances. Hinyokika Kiyo 1986; 32: 757-763.
7. Smirnova EA, Mikhailov IG: Electron microscopic characteristics of oncocytoma of the lung, small intestine and adrenal gland. Arkh Patol 1986; 48: 79-81.
8. Bisceglia M, Ludovico O, Di Mattia A, Ben-Dor D, Sandbank J, Pasquinelli G, Lau SK, Weiss LM: Adrenocortical oncocytic tumors: report of 10 cases and review of the literature. Int J Surg Pathol 2004; 12: 231-243.
9. Shah VN, Premkumar A, Walia R, Kumar S, Nahar U, Bhansali A: Large but benign adrenal mass: adrenal oncocytoma. Indian J Endocrinol Metab 2012; 16: 469-471.
10. Young WF Jr: Clinical practice. The incidentally discovered adrenal mass. N Engl J Med 2007; 356: 601-610.
11. de Krijger RR, Papathomas TG: Adrenocortical neoplasia: evolving concepts in tumorigenesis with an emphasis on adrenal cortical carcinoma variants. Virchows Arch 2012; 460: 9-18.
12. Thway K, Olmos D, Shah C, Flora R, Shipley J, Fisher C: Oncocytic adrenal cortical carcinosarcoma with pleomorphic rhabdomyosarcomatous metastases. Am J Surg Pathol 2012; 36: 470-477.
13. Lee R, Al-Ahmadie HA, Boorjian SA, Gonzalez RR, Badillo C, Badillo F, Reuter VE, Steckel J: A case of incidental adrenocortical oncocytoma. Nat Clin Pract Urol 2006; 3: 618-621.
14. Vara Castrodeza A, Ablanedo Ablanedo P, García García J, Martínez Lara C, Díaz A, Calvo Blanco J: Adrenal oncocytoma. Arch Esp Urol 1999; 52: 525-528.
15. Kitching PA, Patel V, Harach HR: Adrenocortical oncocytoma. J Clin Pathol 1999; 52: 151-153.
16. Macchi C, Rebuffat P, Blandamura S, Piazza M, Macchi V, Fiore D, Nussdorfer GG: Adrenocortical oncocytoma: case report and review of the literature. Tumori 1998; 84: 403-407.
17. Bégin LR: Adrenocortical oncocytoma: case report with immunocytochemical and ultrastructural study. Virchows Arch A Pathol Anat Histopathol 1992; 421: 533-537.
18. Sasano H, Suzuki T, Sano T, Kameya T, Sasano N, Nagura H: Adrenocortical oncocytoma. A true nonfunctioning adrenocortical tumor. Am J Surg Pathol 1991; 15: 949-956.
19. Wong DD, Spagnolo DV, Bisceglia M, Havlat M, McCallum D, Platten MA: Oncocytic adrenocortical neoplasms - a clinicopathologic study of 13 new cases emphasizing the importance of their recognition. Hum Pathol 2011; 42: 489-499.
20. Corsi A, Riminucci M, Petrozza V, Collins MT, Natale ME, Cancrini A, Bianco P: Incidentally detected giant oncocytoma arising in retroperitoneal heterotopic adrenal tissue. Arch Pathol Lab Med 2002; 126: 1118-1122.
21. Nguyen GK, Vriend R, Ronaghan D, Lakey WH: Heterotopic adrenocortical oncocytoma. A case report with light and electron microscopic studies. Cancer 1992; 70: 2681-2684.
22. Segal S, Cytron S, Shenhav S, Gemer O: Adrenocortical oncocytoma in pregnancy. Obstet Gynecol 2001; 98: 916-918.
23. Krech R, Zerban H, Bannasch P: Mitochondrial anomalies in renal oncocytes induced in rats by N-nitrosomorpholine. Eur J Cell Biol 1981; 25: 331-339.
24. Sun CN, White HV, Thompson BW: Oncocytoma (mitochondrioma) of the parotid gland. Arch Pathol 1975; 99: 208-214.
25. Duregon E, Volante M, Cappia S, Cuccurullo A, Bisceglia M, Wong DD, Spagnolo DV, Szpak-Ulczok S, Bollito E, Daffara F, Berruti A, Terzolo M, Papotti M: Oncocytic adrenocortical tumors: diagnostic algorithm and mitochondrial DNA profile in 27 cases. Am J Surg Pathol 2011; 35: 1882-1893.
26. Hartwick RW, Batsakis JG: Non-Warthin's tumor oncocytic lesions. Ann Otol Rhinol Laryngol 1990; 99: 674-677.
27. Hamperl H: Oncocytes and the so-called Hurthle cell tumor. Arch Pathol 1950; 49: 563-570.
28. Seo IS, Henley JD, Min KW: Peculiar cytoplasmic inclusions in oncocytic adrenal cortical tumors: an electron microscopic observation. Ultrastruct Pathol 2002; 26: 229-235.
29. Hoang MP, Ayala AG, Albores-Saavedra J: Oncocytic adrenocortical carcinoma: a morphologic, immunohistochemical and ultrastructural study of four cases. Mod Pathol 2002; 15: 973-978.
30. Lin BT, Bonsib SM, Mierau GW, Weiss LM, Medeiros LJ: Oncocytic adrenocortical neoplasms: a report of seven cases and review of the literature. Am J Surg Pathol 1998; 22: 603-614.
31. Ohtake H, Kawamura H, Matsuzaki M, Yokoyama E, Kitajima M, Onizuka S, Yamakawa M: Oncocytic adrenocortical carcinoma. Ann Diagn Pathol 2010; 14: 204-208.
32. Lázaro Santander R, Andrés Gozalbo C, Cortés Vizcaíno V, Vera Román JM: Lowgrade oncocytic adrenal carcinoma. Arch Esp Urol 2001; 54: 1123-1126.
33. Chisté M, Poppiti RJ, Bianco FJ: Oncocytoma of the adrenal gland medulla. Ann Diagn Pathol 2011, E-pub ahead of print.
34. Sangoi RS, McKenney JK: A tissue microarray-based comparative analysis of novel and traditional immunohistochemical markers in the distinction between adrenal cortical lesions and pheochromocytoma. Am J Surg Pathol 2010; 32: 423-432.
35. Schittenhelm J, Ebner FH, Harter P, Bornemann A: Symptomatic intraspinal oncocytic adrenocortical adenoma. Endocr Pathol 2009; 20: 73-77.
36. Gołkowski F, Buziak-Bereza M, Huszno B, Bałdys- Waligórska A, Stefańska A, Budzyński A, Okoń K, Chrzan R, Urbanik A: The unique case of adrenocortical malignant and functioning oncocytic tumour. Exp Clin Endocrinol Diabetes 2007; 115: 401-404.
37. Botsios D, Blouhos K, Vasiliadis K, Asimaki A, Tsalis K, Betsis D: Adrenocortical oncocytoma - a rare tumor of undefined malignant potential: report of a case. Surg Today 2007; 37: 612-617.
38. Lázaro Santander R, Andrés Gozalbo C, Cortés Vizcaíno V, Vera Román JM: Lowgrade oncocytic adrenal carcinoma. Arch Esp Urol 2001; 54: 1123-1126.
39. el-Naggar AK, Evans DB, Mackay B: Oncocytic adrenal cortical carcinoma. Ultrastruct Pathol 1991; 15: 549-556.
40. Argyriou P, Zisis C, Alevizopoulos N, Kefaloyannis EM, Gennatas C, Petraki CD: Adrenocortical oncocytic carcinoma with recurrent metastases: a case report and review of the literature. World J Surg Oncol 2008; 6: 134-139.
41. Juliano JJ, Cody RL, Suh JH: Metastatic adrenocortical oncocytoma: a case report. Urol Oncol 2008; 26: 198-201.
42. Song SY, Park S, Kim SR, Suh YL: Oncocytic adrenocortical carcinomas: a pathological and immunohistochemical study of four cases in comparison with conventional adrenocortical carcinomas. Pathol Int 2004; 54: 603-610.
43. Medeiros LJ, Weiss LM: New developments in the pathologic diagnosis of adrenal cortical neoplasms. A review. Am J Clin Pathol 1992; 97: 73-83.
44. Sasano H, Suzuki T, Moriya T: Recent advances in histopathology and immunohistochemistry of adrenocortical carcinoma. Endocr Pathol 2006; 17: 345-354.
45. Angeli A, Osella G, Ali A, Terzolo M: Adrenal incidentaloma: an overview of clinical and epidemiological data from the National Italian Study Group. Horm Res 1997; 47: 279-283.
46. Reyna-Villasmil E, Santos-Bolívar J, Prieto-Montaño J: Adrenal oncocytoma. Cir Esp 2011; 89: 692-693.
47. Osman Y, El-Mekresh M, Gomha AM, Mohsen T, Taha N, Hussein N, Eraky I: Percutaneous adrenal biopsy for indeterminate adrenal lesion: complications and diagnostic accuracy. Urol Int 2010; 84: 315-318.
48. Kiriakopoulos A, Papaioannou D, Linos D: Adrenal cortical oncocytoma mimicking pheochromocytoma. Hormones (Athens) 2011; 10: 76-79.
49. Sharma N, Dogra PN, Mathur S: Functional adrenal oncocytoma: a rare neoplasm. Indian J Pathol Microbiol 2008; 51: 531-533.
50. Goel T, Thomas J, Garg S, Rao AC, Reddy S: Adrenal oncocytoma masquerading as a functional tumor. Indian J Urol 2007; 23: 77-78.
51. Li M, Wenig BM: Adrenal oncocytic pheochromocytoma. Am J Surg Pathol 2000; 24: 1552-1557.
52. Lee SS, Baek KH, Lee YS, Lee JM, Kang MI, Cha BY, Lee KW, Son HY, Kang SK: Subclinical Cushing's syndrome associated with an adrenocortical oncocytoma. J Endocrinol Invest 2008; 31: 675-679.
53. Geramizadeh B, Norouzzadeh B, Bolandparvaz S, Sefidbakht S: Functioning adrenocortical oncocytoma: a case report and review of literature. Indian J Pathol Microbiol 2008; 51: 237-239.
54. Xiao GQ, Pertsemlidis DS, Unger PD: Functioning adrenocortical oncocytoma: a case report and review of the literature. Ann Diagn Pathol 2005; 9: 295-297.
55. Kabayegit OY, Soysal D, Oruk G, Ustaoglu B, Kosan U, Solmaz S, Avci A: Adrenocortical oncocytic neoplasm presenting with Cushing's syndrome: a case report. J Med Case Rep 2008; 2: 228.
56. Alexander A, Paulose KP: Oncocytic variant of adrenal carcinoma presenting as Cushing's syndrome. J Assoc Physicians India 1998; 46: 235-237.
57. Terui K, Sakihara S, Kageyama K, Nigawara T, Takayasu S, Matsuhashi Y, Kon A, Yamamoto H, Ohyama C, Sasano H, Suda T: A case of adrenocortical oncocytoma occurring with aldosteronoma. J Clin Endocrinol Metab 2010; 95: 3597-3598.
58. Mete O, Asa SL: Aldosterone-producing adrenal cortical adenoma with oncocytic change and cytoplasmic eosinophilic globular inclusions. Endocr Pathol 2009; 20: 182-185.
59. Lim YJ, Lee SM, Shin JH, Koh HC, Lee YH: Virilizing adrenocortical oncocytoma in a child: a case report. J Korean Med Sci 2010; 25: 1077-1079.
60. Gumy-Pause F, Bongiovanni M, Wildhaber B, Jenkins JJ, Chardot C, Ozsahin H: Adrenocortical oncocytoma in a child. Pediatr Blood Cancer 2008; 50: 718-721.
61. Ciprová V, Povýsil C, Dudorkinová D, Safarík L, Zelinka T: Oncocytic adrenocortical neoplasms. Cesk Patol 2004; 40: 102-105.
62. Erlandson RA, Reuter VE: Oncocytic adrenal cortical adenoma. Ultrastruct Pathol 1991; 15: 539-547.
63. Mwandila M, Waller H, Stott V, Mercer P: A case of a testosterone- secreting oncocytic adrenocortical carcinoma. N Z Med J 2010; 123: 80-82.
64. Tahar GT, Nejib KN, Sadok SS, Rachid LM: Adrenocortical oncocytoma: a case report and review of literature. J Pediatr Surg 2008; 43:E1-E3.
65. Logasundaram R, Parkinson C, Donaldson P, Coode PE: Co-secretion of testosterone and cortisol by a functional adrenocortical oncocytoma. Histopathology 2007; 51: 418-420.
66. Ali AE, Raphael SJ: Functional oncocytic adrenocortical carcinoma. Endocr Pathol 2007; 18: 187-189.
67. Akatsu T, Kameyama K, Araki K, Ashizawa T, Wakabayashi G, Kitajima M: Functioning adrenocortical oncocytoma: the first documented case producing interleukin-6 and review of the literature. J Endocrinol Invest 2008; 31: 68-73.
68. Tirkes T, Gokaslan T, McCrea J, Sandrasegaran K, Hollar MA, Akisik F, Lall C: Oncocytic neoplasms of the adrenal gland. AJR Am J Roentgenol 2011; 196: 592-596.
69. Boland GWL: Adrenal imaging. Abdom Imaging 2011; 36: 472-482.
70. Shah RK, Oto A, Ozkan OS, Ernst RD, Hernandez JA, Chaudhary HB, Koroglu M: Adrenal oncocytoma: US and CT findings. JBRBTR 2004; 87: 180-182.
71. Poretti D, Mazzarol G, Bonomo G, Casadio C, Bellomi M: Adrenocortical oncocytoma: case report. Clin Imaging 2003; 27: 426-430.
72. Park BK, Kim B, Ko K, Jeong SY, Kwon GY: Adrenal masses falsely diagnosed as adenomas on unenhanced and delayed contrastenhanced computed tomography: pathological correlation. Eur Radiol 2006; 16: 642-647.
73. Haider MA, Ghai S, Jhaveri K, Lockwood G: Chemical shift MR imaging of hyperattenuating (>10 HU) adrenal masses: does it still have a role? Radiology 2004; 231: 711-716.
74. Savci G, Yazici Z, Sahin N, Akgöz S, Tuncel E: Value of chemical shift subtraction MRI in characterization of adrenal masses. AJR Am J Roentgenol 2006; 186: 130-135.
75. Monk IP, Lahiri R, Sivaprakasam R, Malhotra S, Praseedom RK, Jah A: Adrenocortical oncocytoma: review of imaging and histopathological implications. Int J Surg Case Rep 2010; 1: 30-32.
76. Kekis P, Seretis C, Lagoudianakis E, Gemenetzis G, Koronakis N, Keramidaris D, Manouras I, Manouras A: Laparoscopic approach to a large adrenocortical oncocytoma: a case report and review of the literature. Int J Surg Case Rep 2012; 3: 279-282.
77. Rosenkrantz AB, Do RK, Hajdu CH: Imaging appearance of bulk fat within an oncocytic adrenocortical neoplasm, a rare and potentially malignant tumour. Br J Radiol 2010; 83: 204-207.
78. Friedrich-Rust M, Glasemann T, Polta A, Eichler K, Holzer K, Kriener S, Herrmann E, Nierhoff J, Bon D, Bechstein WO, Vogl T, Zeuzem S, Bojunga J: Differentiation between benign and malignant adrenal mass using contrast-enhanced ultrasound. Ultraschall Med 2011; 32: 460-471.
79. Kim DJ, Chung JJ, Ryu YH, Hong SW, Yu JS, Kim JH: Adrenocortical oncocytoma displaying intense activity on 18F-FDG-PET: a case report and a literature review. Ann Nucl Med 2008; 22: 821-824.
80. Acar C, Akkas BE, Sen I, Sozen S, Kitapci MT: False positive 18F-FDG PET scan in adrenal oncocytoma. Urol Int 2008; 80: 444-447.
81. Minamimoto R, Yamanaka S, Kawamoto M, Endoh M, Nishito R, Yoshida K, Nakaigawa N, Yao M, Kubota Y, Inoue T: High FDG uptake on oncocytoma located in the retroperitoneum mimicking malignancy. Clin Nucl Med 2007; 32: 582-583.
82. Padberg BC, Rordorf T, Suter SL, Pfeiffer D, Wild D, Schröder S: 123I-Metaiodobenzylguanidine (MIBG) scintigraphy: paradoxical positivity in an oncocytic adrenocortical carcinoma. Pathologe 2007; 28: 281-284.
83. Krishnamurthy S, Ordonez NG, Shelton TO, Ayala AG, Sneige N: Fine-needle aspiration cytology of a case of oncocytic adrenocortical carcinoma. Diagn Cytopathol 2000; 22: 299-303.
84. Cham E, Watkin W, Goldschmidt R, Liu L: Fine needle aspiration cytology of adrenocortical oncocytic neoplasm: a case report. Acta Cytol 2010; 54: 627-634.
85. Wragg T, Nguyen GK: Cytopathology of adrenal cortical oncocytoma. Diagn Cytopathol 2001; 24: 222-223.
86. Lee CK, Choi KH, Cha YJ, Bum JH, Lee HH, Kim MS, Park WK, Yang SC, Han WK: Large oncocytic adrenocortical tumor with uncertain malignant potential. Korean J Urol 2011; 52: 650-652.
87. Farah-Klibi F, Ben Slama S, Ferchichi L, Ben Temime L, Ben Jilani S, Zermani R: Adrenal gland oncocytoma. Tunis Med 2011; 89: 309-310.
88. Bouasker I, Zoghlami A, Farah Klibi F, Smaali I, El Ouaer MA, Zermani R, Dziri C: Adreno-cortical oncocytoma: a case report. Tunis Med 2010; 88: 353-356.
89. Pazooki A, Vaziri M: Incidental adrenocortical oncocytoma. BMJ Case Rep DOI: 10.1136/bcr.12.2008.1405.
90. Tian XJ, Huang Y, Lu J, Ma LL: Laparoscopic adrenocortical oncocytoma resection. Chin Med J 2008; 121: 862-864.
91. Eldahshan S, Celia A, Zeccolini G, Guerini A, Breda G: Laparoscopic transperitoneal adrenalectomy for adrenocortical oncocytoma. Arch Ital Urol Androl 2008; 80: 82-84.
92. Farkas A, Horányi J, Gláz E, Kulka J: Oncocytic tumor of the adrenal gland. Orv Hetil 2005; 146: 1453-1458.
93. Young JA, Chapman WH 3rd, Kim VB, Albrecht RJ, Ng PC, Nifong LW, Chitwood WR Jr: Robotic-assisted adrenalectomy for adrenal incidentaloma: case and review of the technique. Surg Laparosc Endosc Percutan Tech 2002; 12: 126-130.
94. Modi P, Goel R, Kadam G: Retroperitoneoscopic partial adrenalectomy for large adrenocortical oncocytoma. J Endourol 2007; 21: 419-422.
95. Thway K, Olmos D, Shah C, Flora R, Shipley J, Fisher C: Oncocytic adrenal cortical carcinosarcoma with pleomorphic rhabdomyosarcomatous metastases. Am J Surg Pathol 2012; 36: 470-477.
96. Allolio B, Fassnacht M: Clinical review: adrenocortical carcinoma. J Clin Endocrinol Metab 2006; 91: 2027-2037.
97. Kurek R, Von Knobloch R, Feek U, Heidenreich A, Hofmann R: Local recurrence of an oncocytic adrenocortical carcinoma with ovary metastasis. J Urol 2001; 166: 985.
98. Terzolo M, Angeli A, Fassnacht M: Adjuvant mitotane treatment for adrenocortical carcinoma. N Engl J Med 2007; 356: 2372-2380.