A candidate gene study for the association of host single nucleotide polymorphisms with liver cirrhosis risk in chinese hepatitis B patients

Genetic Testing and Molecular Biomarkers

Volumn 17, Issue 9, 2013, Pages 681-686

  Peng, Lijun ^a,b   Guo, Jinsheng ^a   Zhang, Zhe ^a   Liu, Lili ^a   Cao, Yirong ^a   Shi, Hong ^a   Wang, Jian ^a   Wang, Jiyao ^a   Friedman, Scott L ^c   Sninsky, John J ^d  

^a FUDAN UNIVERSITY   (China)

^b LINYI PEOPLE'S HOSPITAL   (China)

^c MOUNT SINAI HOSPITAL   (United States)

^d CELERA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSIENT RECEPTOR POTENTIAL CHANNEL M5; AZIN1 PROTEIN, HUMAN; CARRIER PROTEIN; TRANSIENT RECEPTOR POTENTIAL CHANNEL M; TRPM5 PROTEIN, HUMAN;

ADULT; ARTICLE; CHILD PUGH SCORE; CHINESE; CHRONICITY; CONTROLLED STUDY; DECOMPENSATED LIVER CIRRHOSIS; DISEASE COURSE; FEMALE; GENOTYPE; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; LIVER CIRRHOSIS; MAJOR CLINICAL STUDY; MALE; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; PERSISTENT INFECTION; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; VIRAL CLEARANCE; ASIAN CONTINENTAL ANCESTRY GROUP; CHINA; CLINICAL TRIAL; COMPLICATION; GENETICS; MULTICENTER STUDY; PATHOLOGY;

HEPATITIS B VIRUS;

ASIAN CONTINENTAL ANCESTRY GROUP; CARRIER PROTEINS; CHINA; FEMALE; GENOTYPE; HEPATITIS B; HUMANS; LIVER CIRRHOSIS; MALE; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS; TRPM CATION CHANNELS;

EID: 84883680673     PISSN: 19450265     EISSN: 19450257     Source Type: Journal    
DOI: 10.1089/gtmb.2013.0058     Document Type: Article

References (33)

1. Beutler B (2004) Inferences, questions and possibilities in Tolllike receptor signalling. Nature 430:257-263. (Pubitemid 38902439)
2. Chen CJ, Wang LY, Yu MW (2000) Epidemiology of hepatitis B virus infection in the Asia-Pacific region. J Gastroenterol Hepatol 15 Suppl: E3-E6.
3. Cheong JY, Cho SW, Hwang IL, et al. (2006) Association between chronic hepatitis B virus infection and interleukin-10, tumor necrosis factor-alpha gene promoter polymorphisms. J Gastroenterol Hepatol 21:1163-1169.
4. Curto TM, Lagier RJ, Lok AS, et al. (2011) Predicting cirrhosis and clinical outcomes in patients with advanced chronic hepatitis C with a panel of genetic markers (CRS7). Pharmacogenet Genomics 21:851-860.
5. Day CP (2005) Genetic studies to identify hepatic fibrosis genes and SNPs in human populations. Methods Mol Med 117:315-331.
6. Du T, Guo XH, Zhu XL, et al. (2006) Association of TNF-alpha promoter polymorphisms with the outcomes of hepatitis B virus infection in Chinese Han population. J Viral Hepat 13:618-624. (Pubitemid 44232546)
7. Fattovich G, Bortolotti F, Donato F (2008) Natural history of chronic hepatitis B: special emphasis on disease progression and prognostic factors. J Hepatol 48:335-352.
8. Guo J, Loke J, Zheng F, et al. (2009) Functional linkage of cirrhosis-predictive single nucleotide polymorphisms of Tolllike receptor 4 to hepatic stellate cell responses. Hepatology 49:960-968.
9. Huang H, Shiffman ML, Friedman S, et al. (2007) A 7 gene signature identifies the risk of developing cirrhosis in patients with chronic hepatitis C. Hepatology 46:297-306. (Pubitemid 47344763)
10. Jurinke C, Oeth P, van den Boom D (2004) MALDI-TOF mass spectrometry: a versatile tool for high-performance DNA analysis. Mol Biotechnol 26:147-164.
11. Kamatani Y, Wattanapokayakit S, Ochi H, et al. (2009) A genomewide association study identifies variants in the HLA-DP locus associated with chronic hepatitis B in Asians. Nat Genet 41:591-595.
12. Karlsen TH, Melum E, Franke A (2010) The utility of genome-wide association studies in hepatology. Hepatology 51:1833-1842.
13. Kaske S, Krasteva G, Konig P, et al. (2007) TRPM5, a taste-signaling transient receptor potential ion-channel, is a ubiquitous signaling component in chemosensory cells. BMC Neurosci 8:49.
14. Kraveka JM, Li L, Szulc ZM, et al. (2007) Involvement of dihydroceramide desaturase in cell cycle progression in human neuroblastoma cells. J Biol Chem 282:16718-16728. (Pubitemid 47093220)
15. Lavanchy D (2004) Hepatitis B virus epidemiology, disease burden, treatment, and current and emerging prevention and control measures. J Viral Hepat 11:97-107. (Pubitemid 38365759)
16. Liu M, Cao B, Zhang H, et al. (2006) Association of interferongamma gene haplotype in the Chinese population with hepatitis B virus infection. Immunogenetics 58:859-864. (Pubitemid 44813044)
17. Mangold U (2006) Antizyme inhibitor: mysterious modulator of cell proliferation. Cell Mol Life Sci 63:2095-2101. (Pubitemid 44465684)
18. Marcolongo M, Young B, Pero FD, et al. (2009) A seven-gene signature (cirrhosis risk score) predicts liver fibrosis progression in patients with initially mild chronic hepatitis C. Hepatology 50:1038-1044.
19. McMahon BJ (2009) The natural history of chronic hepatitis B virus infection. Hepatology 49:S45-S55.
20. Paris AJ, Snapir Z, Christopherson CD, et al. (2011) A polymorphism that delays fibrosis in hepatitis C promotes alternative splicing of AZIN1, reducing fibrogenesis. Hepatology 54:2198-2207.
21. Powell EE, Edwards-Smith CJ, Hay JL, et al. (2000) Host genetic factors influence disease progression in chronic hepatitis C. Hepatology 31:828-833. (Pubitemid 30169926)
22. Prawitt D, Monteilh-Zoller MK, Brixel L, et al. (2003) TRPM5 is a transient Ca2 + -activated cation channel responding to rapid changes in [Ca2+]i. Proc Natl Acad Sci U S A 100:15166-15171. (Pubitemid 37518034)
23. Ragoussis J, Elvidge GP, Kaur K, et al. (2006) Matrix-assisted laser desorption/ionisation, time-of-flight mass spectrometry in genomics research. PLoS Genet 2:e100.
24. Romeo S, Kozlitina J, Xing C, et al. (2008) Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease. Nat Genet 40:1461-1465.
25. Seki E, De Minicis S, Osterreicher CH, et al. (2007) TLR4 enhances TGF-beta signaling and hepatic fibrosis. Nat Med 13:1324-1332. (Pubitemid 350073596)
26. Shepard CW, Simard EP, Finelli L, et al. (2006) Hepatitis B virus infection: epidemiology and vaccination. Epidemiol Rev 28:112-125. (Pubitemid 44289094)
27. Suneetha PV, Sarin SK, Goyal A, et al. (2006) Association between vitamin D receptor, CCR5, TNF-alpha and TNF-beta gene polymorphisms and HBV infection and severity of liver disease. J Hepatol 44:856-863.
28. Takata K (2006) Aquaporin-2 (AQP2): its intracellular compartment and trafficking. Cell Mol Biol (Noisy-le-grand) 52:34-39. (Pubitemid 46683294)
29. Ternes P, Franke S, Zahringer U, et al. (2002) Identification and characterization of a sphingolipid delta 4-desaturase family. J Biol Chem 277:25512-25518. (Pubitemid 34951866)
30. Tian C, Stokowski RP, Kershenobich D, et al. (2009) Variant in PNPLA3 is associated with alcoholic liver disease. Nat Genet 42:21-23.
31. Valenti L, Al-Serri A, Daly AK, et al. (2010) Homozygosity for the patatin-like phospholipase-3/adiponutrin I148M polymorphism influences liver fibrosis in patients with nonalcoholic fatty liver disease. Hepatology 51:1209-1217.
32. Yin JH, Zhao J, Zhang HW, et al. (2010) HBV genotype C is independently associated with cirrhosis in community-based population. World J Gastroenterol 16:379-383.
33. Yuen MF, Sablon E, Yuan HJ, et al. (2003) Significance of hepatitis B genotype in acute exacerbation, HBeAg seroconversion, cirrhosis-related complications, and hepatocellular carcinoma. Hepatology 37:562-567. (Pubitemid 36258778)