Alterations in endogenous opioid functional measures in chronic back pain

Journal of Neuroscience

Volumn 33, Issue 37, 2013, Pages 14729-14737

  Martikainen, Ilkka K ^a   Peciña, Marta ^a   Love, Tiffany M ^a,b   Nuechterlein, Emily B ^a,b   Cummiford, Chelsea M ^a   Green, Carmen R ^b,c   Harris, Richard E ^c   Stohler, Christian S ^d   Zubieta, Jon Kar ^a,b  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF MARYLAND DENTAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARFENTANIL; GABAPENTIN; MU OPIATE RECEPTOR; MUSCLE RELAXANT AGENT; NEUROTRANSMITTER; OPIATE RECEPTOR; PARACETAMOL; SEROTONIN NORADRENALIN REUPTAKE INHIBITOR;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FIBROMYALGIA; HUMAN; LOW BACK PAIN; MALE; NEUROIMAGING; NEUROTRANSMISSION; NUCLEAR MAGNETIC RESONANCE IMAGING; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; VISUAL ANALOG SCALE; VOXEL BASED MORPHOMETRY;

ADULT; ANALGESICS, OPIOID; ANALYSIS OF VARIANCE; BACK PAIN; BRAIN; BRAIN MAPPING; CARBON RADIOISOTOPES; CASE-CONTROL STUDIES; CHRONIC DISEASE; FEMALE; FENTANYL; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; PAIN MEASUREMENT; PAIN THRESHOLD; POSITRON-EMISSION TOMOGRAPHY; SYNAPTIC TRANSMISSION;

EID: 84883657838     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1400-13.2013     Document Type: Article

References (65)

1. Andersson GB (1999) Epidemiological features of chronic low-back pain. Lancet 354:581-585. CrossRef Medline
2. Apkarian AV, Sosa Y, Sonty S, Levy RM, Harden RN, Parrish TB, Gitelman DR (2004) Chronic back pain is associated with decreased prefrontal and thalamic gray matter density. J Neurosci 24:10410-10415. CrossRef Medline
3. Ashburner J, Friston KJ (2005) Unified segmentation. Neuroimage 26:839-851. CrossRef Medline
4. Balagué F, Mannion AF, Pellisé F, Cedraschi C (2012) Non-specific low back pain. Lancet 379:482-491. CrossRef Medline
5. Baliki MN, Baria AT, Apkarian AV (2011) The cortical rhythms of chronic back pain. J Neurosci 31:13981-13990. CrossRef Medline
6. Baliki MN, Petre B, Torbey S, Herrmann KM, Huang L, Schnitzer TJ, Fields HL, Apkarian AV (2012) Corticostriatal functional connectivity predicts transition to chronic back pain. Nat Neurosci 15:1117-1119. CrossRef Medline
7. Bencherif B, Fuchs PN, Sheth R, Dannals RF, Campbell JN, Frost JJ (2002) Pain activation of human supraspinal opioid pathways as demonstrated by [11C]-carfentanil and positron emission tomography (PET). Pain 99: 589-598. CrossRef Medline
8. Bruehl S, Chung OY (2006) Parental history of chronic pain may be associated with impairments in endogenous opioid analgesic systems. Pain 124: 287-294. CrossRef Medline
9. Bruehl S, Chung OY, Ward P, Johnson B (2004) Endogenous opioids and chronic pain intensity: interactions with level of disability. Clin J Pain 20:283-292. CrossRef Medline
10. Bruehl S, Chung OY, Chont M (2010) Chronic pain-related changes in endogenous opioid analgesia: a case report. Pain 148:167-171. CrossRef Medline
11. Brunton J, Charpak S (1998) μ-Opioid peptides inhibit thalamic neurons. J Neurosci 18:1671-1678. Medline
12. Carr KD, Bak TH (1988) Medial thalamic injection of opioid agonists: muagonist increases while kappa-agonist decreases stimulus thresholds for pain and reward. Brain Res 441:173-184. CrossRef Medline
13. Cherny NI, Thaler HT, Friedlander-Klar H, Lapin J, Foley KM, Houde R, Portenoy RK (1994) Opioid responsiveness of cancer pain syndromes caused by neuropathic or nociceptive mechanisms: a combined analysis of controlled, single-dose studies. Neurology 44:857-861. CrossRef Medline
14. Dadabhoy D, Clauw DJ (2006) Therapy insight: fibromyalgia-a different type of pain needing a different type of treatment. Nat Clin Pract Rheumatol 2:364-372. CrossRef Medline
15. Dannals RF, Ravert HT, Frost JJ, Wilson AA, Burns HD, Wagner HN Jr (1985) Radiosynthesis of an opiate receptor binding radiotracer: [11C]carfentanil. Int J Appl Radiat Isot 36:303-306. CrossRef Medline
16. Flor H, Braun C, Elbert T, Birbaumer N (1997) Extensive reorganization of primary somatosensory cortex in chronic back pain patients. Neurosci Lett 224:5-8. CrossRef Medline
17. Friston KJ, Frith CD, Liddle PF, Frackowiak RS (1991) Comparing functional (PET) images: the assessment of significant change. J Cereb Blood Flow Metab 11:690-699. CrossRef Medline
18. Giesecke T, Gracely RH, Grant MA, Nachemson A, Petzke F, Williams DA, Clauw DJ (2004) Evidence of augmented central pain processing in idiopathic chronic low back pain. Arthritis Rheum 50:613-623. CrossRef Medline
19. Grachev ID, Fredrickson BE, Apkarian AV (2000) Abnormal brain chemistry in chronic back pain: an in vivo proton magnetic resonance spectroscopy study. Pain 89:7-18. CrossRef Medline
20. Guilbaud G, Benoist JM, Jazat F, Gautron M (1990) Neuronal responsiveness in the ventrobasal thalamic complex of rats with an experimental peripheral mononeuropathy. J Neurophysiol 64:1537-1554. Medline
21. Gustin SM, Peck CC, Wilcox SL, Nash PG, Murray GM, Henderson LA (2011) Different pain, different brain: thalamic anatomy in neuropathic and non-neuropathic chronic pain syndromes. J Neurosci 31:5956-5964. CrossRef Medline
22. Harris RE, Clauw DJ, Scott DJ, McLean SA, Gracely RH, Zubieta JK (2007) Decreased central μ-opioid receptor availability in fibromyalgia. J Neurosci 27:10000-10006. CrossRef Medline
23. Harris RE, Zubieta JK, Scott DJ, Napadow V, Gracely RH, Clauw DJ (2009) Traditional Chinese acupuncture and placebo (sham) acupuncture are differentiated by their effects on mu-opioid receptors (MORs). Neuroimage 47:1077-1085. CrossRef Medline
24. Helmstetter FJ, Tershner SA, Poore LH, Bellgowan PS (1998) Antinociception following opioid stimulation of the basolateral amygdala is expressed through the periaqueductal gray and rostral ventromedial medulla. Brain Res 779:104-118. CrossRef Medline
25. Henderson LA, Peck CC, Petersen ET, Rae CD, Youssef AM, Reeves JM, Wilcox SL, Akhter R, Murray GM, Gustin SM (2013) Chronic pain: lost inhibition? J Neurosci 33:7574-7582. CrossRef Medline
26. Iadarola MJ, Max MB, Berman KF, Byas-Smith MG, Coghill RC, Gracely RH, Bennett GJ (1995) Unilateral decrease in thalamic activity observed with positron emission tomography in patients with chronic neuropathic pain. Pain 63:55-64. CrossRef Medline
27. Ivo R, Nicklas A, Dargel J, Sobottke R, Delank KS, Eysel P, Weber B (2013) Brain structural and psychometric alterations in chronic low back pain. Eur Spine J. Advance online publication. Retrieved August 7, 2013. doi: 10.1007/s00586-013-2692-x. CrossRef Medline
28. Jadad AR, Carroll D, Glynn CJ, Moore RA, McQuay HJ (1992) Morphine responsiveness of chronic pain: double-blind randomised crossover study with patient-controlled analgesia. Lancet 339:1367-1371. CrossRef Medline
29. Jewett DM (2001) A simple synthesis of [11C]carfentanil using an extraction disk instead of HPLC. Nucl Med Biol 28:733-734. CrossRef Medline
30. Jones AK, Cunningham VJ, Ha-Kawa S, Fujiwara T, Luthra SK, Silva S, Derbyshire S, Jones T (1994) Changes in central opioid receptor binding in relation to inflammation and pain in patients with rheumatoid arthritis. Br J Rheumatol 33:909-916. CrossRef Medline
31. Jones AK, Kitchen ND, Watabe H, Cunningham VJ, Jones T, Luthra SK, Thomas DG (1999) Measurement of changes in opioid receptor binding in vivo during trigeminal neuralgic pain using [11C] diprenorphine and positron emission tomography. J Cereb Blood Flow Metab 19:803-808. Medline
32. Jones AK, Watabe H, Cunningham VJ, Jones T (2004) Cerebral decreases in opioid receptor binding in patients with central neuropathic pain measured by [11C]diprenorphine binding and PET. Eur J Pain 8:479-485. CrossRef Medline
33. Kuijpers T, van Middelkoop M, Rubinstein SM, Ostelo R, Verhagen A, Koes BW, van Tulder MW (2011) A systematic review on the effectiveness of pharmacological interventions for chronic non-specific low-back pain. Eur Spine J 20:40-50. CrossRef Medline
34. Lipman JJ, Miller BE, Mays KS, Miller MN, North WC, Byrne WL (1990) Peak B endorphin concentration in cerebrospinal fluid: reduced in chronic pain patients and increased during the placebo response. Psychopharmacology (Berl) 102:112-116. CrossRef Medline
35. Logan J, Fowler JS, Volkow ND, Wang GJ, Ding YS, Alexoff DL (1996) Distribution volume ratios without blood sampling from graphical analysis of PET data. J Cereb Blood Flow Metab 16:834-840. Medline
36. Maarrawi J, Peyron R, Mertens P, Costes N, Magnin M, Sindou M, Laurent B, Garcia-Larrea L (2007) Differential brain opioid receptor availability in central and peripheral neuropathic pain. Pain 127:183-194. CrossRef Medline
37. Mansour A, Khachaturian H, Lewis ME, Akil H, Watson SJ (1987) Autoradiographic differentiation of μ, α, and κ opioid receptors in the rat forebrain and midbrain. J Neurosci 7:2445-2464. Medline
38. McGaraughty S, Heinricher MM (2002) Microinjection of morphine into various amygdaloid nuclei differentially affects nociceptive responsiveness and RVM neuronal activity. Pain 96:153-162. CrossRef Medline
39. Melzack R, Torgerson WS (1971) On the language of pain. Anesthesiology 34:50-59. CrossRef Medline
40. Minoshima S, Koeppe RA, Mintun MA, Berger KL, Taylor SF, Frey KA, Kuhl DE (1993) Automated detection of the intercommissural line for stereotactic localization of functional brain images. J Nucl Med 34:322-329. Medline
41. Neugebauer V, Li W, Bird GC, Han JS (2004) The amygdala and persistent pain. Neuroscientist 10:221-234. CrossRef Medline
42. O'Neill S, Manniche C, Graven-Nielsen T, Arendt-Nielsen L (2007) Generalized deep-tissue hyperalgesia in patients with chronic low-back pain. Eur J Pain 11:415-420. CrossRef Medline
43. Paulson PE, Casey KL, Morrow TJ (2002) Long-term changes in behavior and regional cerebral blood flow associated with painful peripheral mononeuropathy in the rat. Pain 95:31-40. CrossRef Medline
44. Phelps EA, LeDoux JE (2005) Contributions of the amygdala to emotion processing: from animal models to human behavior. Neuron 48:175-187. CrossRef Medline
45. Porrino LJ, Crane AM, Goldman-Rakic PS (1981) Direct and indirect pathways from the amygdala to the frontal lobe in rhesus monkeys. J Comp Neurol 198:121-136. CrossRef Medline
46. Puig MM, Laorden ML, Miralles FS, Olaso MJ (1982) Endorphin levels in cerebrospinal fluid of patients with postoperative and chronic pain. Anesthesiology 57:1-4. CrossRef Medline
47. Rinaldi PC, Young RF, Albe-Fessard D, Chodakiewitz J (1991) Spontaneous neuronal hyperactivity in the medial and intralaminar thalamic nuclei of patients with deafferentation pain. J Neurosurg 74:415-421. CrossRef Medline
48. Rodriguez-Raecke R, Niemeier A, Ihle K, Ruether W, May A (2009) Brain gray matter decrease in chronic pain is the consequence and not the cause of pain. J Neurosci 29:13746-13750. CrossRef Medline
49. Ruscheweyh R, Deppe M, Lohmann H, Stehling C, Flöel A, Ringelstein EB, Knecht S (2011) Pain is associated with regional grey matter reduction in the general population. Pain 152:904-911. CrossRef Medline
50. Schmidt CO, Schweikert B, Wenig CM, Schmidt U, Gockel U, Freynhagen R, Tölle TR, Baron R, Kohlmann T (2009) Modelling the prevalence and cost of back pain with neuropathic components in the general population. Eur J Pain 13:1030-1035. CrossRef Medline
51. Schmidt-Wilcke T, Leinisch E, Gänssbauer S, Draganski B, Bogdahn U, Altmeppen J, May A (2006) Affective components and intensity of pain correlate with structural differences in gray matter in chronic back pain patients. Pain 125:89-97. CrossRef Medline
52. Seminowicz DA, Wideman TH, Naso L, Hatami-Khoroushahi Z, Fallatah S, Ware MA, Jarzem P, Bushnell MC, Shir Y, Ouellet JA, Stone LS (2011) Effective treatment of chronic low back pain in humans reverses abnormal brain anatomy and function. J Neurosci 31:7540-7550. CrossRef Medline
53. Sora I, Takahashi N, Funada M, Ujike H, Revay RS, Donovan DM, Miner LL, Uhl GR (1997) Opiate receptor knockout mice define mu receptor roles in endogenous nociceptive responses and morphine-induced analgesia. Proc Natl Acad Sci U S A 94:1544-1549. CrossRef Medline
54. Stohler CS, Kowalski CJ (1999) Spatial and temporal summation of sensory and affective dimensions of deep somatic pain. Pain 79:165-173. CrossRef Medline
55. Von Korff M, Crane P, Lane M, Miglioretti DL, Simon G, Saunders K, Stang P, Brandenburg N, Kessler R (2005) Chronic spinal pain and physicalmental comorbidity in the United States: results from the national comorbidity survey replication. Pain 113:331-339. CrossRef Medline
56. Watson D, Clark LA (1999) Manual for the positive and negative affect schedule-expanded form. Iowa City, IA: University of Iowa.
57. Wiesinger B, Malker H, Englund E, Wänman A (2007) Back pain in relation to musculoskeletal disorders in the jaw-face: a matched case-control study. Pain 131:311-319. CrossRef Medline
58. Willoch F, Schindler F, Wester HJ, Empl M, Straube A, Schwaiger M, Conrad B, Tölle TR (2004) Central poststroke pain and reduced opioid receptor binding within pain processing circuitries: a [11C]diprenorphine PET study. Pain 108:213-220. CrossRef Medline
59. Wolfe F, Smythe HA, Yunus MB, Bennett RM, Bombardier C, Goldenberg DL, Tugwell P, Campbell SM, Abeles M, Clark P (1990) The American College of Rheumatology 1990 criteria for the classification of fibromyalgia. Report of the Multicenter Criteria Committee. Arthritis Rheum 33: 160-172. CrossRef Medline
60. Woolf CJ, Salter MW (2000) Neuronal plasticity: increasing the gain in pain. Science 288:1765-1769. CrossRef Medline
61. Worsley KJ, Evans AC, Marrett S, Neelin P (1992) A three-dimensional statistical analysis for CBF activation studies in human brain. J Cereb Blood Flow Metab 12:900-918. CrossRef Medline
62. Zhang X, Ashton-Miller JA, Stohler CS (1993) A closed-loop system for maintaining constant experimental muscle pain in man. IEEE Trans Biomed Eng 40:344-352. CrossRef Medline
63. Zubieta JK (2008) Forebrain opiates. In: Science of pain, Ed 1 (Basbaum A, Bushnell MC, ed), pp 821-831. Amsterdam: Academic.
64. Zubieta JK, Smith YR, Bueller JA, Xu Y, Kilbourn MR, Jewett DM, Meyer CR, Koeppe RA, Stohler CS (2001) Regional mu opioid receptor regulation of sensory and affective dimensions of pain. Science 293:311-315. CrossRef Medline
65. Zubieta JK, Smith YR, Bueller JA, Xu Y, Kilbourn MR, Jewett DM, Meyer CR, Koeppe RA, Stohler CS (2002) μ-Opioid receptor-mediated antinociceptive responses differ in men and women. J Neurosci 22:5100-5107. Medline