Plasma sodium setpoint: Is it constant or changed by hemodialysis prescription?

ASAIO Journal

Volumn 59, Issue 5, 2013, Pages 497-504

  Thomson, Benjamin K A ^a,b   Huang, Shih Han S ^a,b   Chan, Christopher T ^c   House, Andrew A ^a   Lindsay, Robert M ^a,b  

^a LONDON HEALTH SCIENCES CENTRE   (Canada)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

^c TORONTO GENERAL HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CONFIDENCE INTERVAL; DIALYSATES; PRE TRANSITIONS; SETPOINTS;

HEMODIALYZERS; OXYGEN VACANCIES; SODIUM;

DIALYSIS;

ALBUMIN; PHOSPHATE; SODIUM;

ADULT; ALBUMIN BLOOD LEVEL; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DIALYSATE; ELECTRONIC MEDICAL RECORD; FEMALE; FREQUENT NOCTURNAL HEMODIALYSIS; HEMODIALYSIS; HEMODIALYSIS PATIENT; HOME DIALYSIS; HUMAN; INTERMITTENT CONVENTIONAL HEMODIALYSIS; INTERMITTENT NOCTURNAL HEMODIALYSIS; KIDNEY FUNCTION; MAJOR CLINICAL STUDY; MALE; MORTALITY; PHOSPHATE BLOOD LEVEL; REFERENCE VALUE; RENAL REPLACEMENT THERAPY; RETROSPECTIVE STUDY; SHORT HOURS DAILY DIALYSIS; SODIUM BLOOD LEVEL; SODIUM SETPOINT; TREATMENT DURATION; ULTRAFILTRATION;

ADULT; FEMALE; HEMODIALYSIS SOLUTIONS; HEMODIALYSIS, HOME; HOMEOSTASIS; HUMANS; KIDNEY FAILURE, CHRONIC; MALE; MIDDLE AGED; REGRESSION ANALYSIS; RETROSPECTIVE STUDIES; SODIUM; TIME FACTORS; TREATMENT OUTCOME;

EID: 84883656252     PISSN: 10582916     EISSN: 1538943X     Source Type: Journal    
DOI: 10.1097/MAT.0b013e31829ed829     Document Type: Article

References (19)

1. Zerbe RL, Miller JZ, Robertson GL: The reproducibility and heritability of individual differences in osmoregulatory function in normal human subjects. J Lab Clin Med 117: 51-59, 1991.
2. Argent NB, Burrell LM, Goodship T.H., Wilkinson R., Baylis PH: Osmoregulation of thirst and vasopressin release in severe chronic renal failure. Kidney Int 39: 295-300, 1991.
3. Keen ML, Gotch FA: The association of the sodium "setpoint" to interdialytic weight gain and blood pressure in hemodialysis patients. Int J Artif Organs 30: 971-979, 2007.
4. Basile C, Libutti P, Lisi P., at al: Sodium setpoint and gradient in bicarbonate hemodialysis. J Nephrol 2012.
5. Peixoto AJ, Gowda N, Parikh C.R., Santos SF: Long-term stability of serum sodium in hemodialysis patients. Blood Purif 29: 264-267, 2010.
6. Krautzig S, Janssen U, Koch K.M., Granolleras C., Shaldon S: Dietary salt restriction and reduction of dialysate sodium to control hypertension in maintenance haemodialysis patients. Nephrol Dial Transplant 13: 552-553, 1998. (Pubitemid 28119030)
7. Farmer CKT, Donohoe P, Dallyn P.E., Cox J., Koingswood JC, Goldsmith DJ: Low sodium hemodialysis without fluid removal improves blood pressure control in hemodialysis patients. Nephrology 5; 237-241, 2000. (Pubitemid 32164458)
8. Ferraboli R, Manuel C, Abensur H., Elias R, Luders C: Reduction of sodium dialysate for hypertensive HD patients: Analysis of ben-efficial and adverse effects. J Am Soc Nephrol 13; 211a, 2002.
9. de Paula F.M., Peixoto AJ, Pinto L.V., Dorigo D., Patricio PJ, Santos SF: Clinical consequences of an individualized dialysate sodium prescription in hemodialysis patients. Kidney Int 66: 1232-1238, 2004. (Pubitemid 39121033)
10. Lambie SH, Taal MW, Fluck R.J., McIntyre CW: Online conductivity monitoring: Validation and usefulness in a clinical trial of reduced dialysate conductivity. ASAIO J 51: 70-76, 2005. (Pubitemid 40165255)
11. Thein H, Haloob I, Marshall MR: Associations of a facility level decrease in dialysate sodium concentration with blood pressure and interdialytic weight gain. Nephrol Dial Transplant 22: 2630-2639, 2007. (Pubitemid 47370840)
12. Sayarlioglu H, Erkoc R, Tuncer M., et al.: Effects of low sodium dialysate in chronic hemodialysis patients: An echocardiographic study. Ren Fail 29: 143-146, 2007.
13. Hecking M, Kainz A, Hörl WH, Herkner H, Sunder-Plassmann G: Sodium setpoint and sodium gradient: Influence on plasma sodium change and weight gain. Am J Nephrol 33: 39-48, 2011.
14. Foley RN, Herzog CA, Collins AJ; United States Renal Data System: Blood pressure and long-term mortality in United States hemo-dialysis patients: USRDS Waves 3 and 4 Study. Kidney Int 62: 1784-1790, 2002. (Pubitemid 35286287)
15. Hecking M, Karaboyas A, Saran R., et al.: Predialysis serum sodium level, dialysate sodium, and mortality in maintenance hemo-dialysis patients: The Dialysis Outcomes and Practice Patterns Study (DOPPS). Am J Kidney Dis 59: 238-248, 2012.
16. Mc Causland F.R., Brunelli SM, Waikar SS: Dialysate sodium, serum sodium and mortality in maintenance hemodialysis. Nephrol Dial Transplant 27: 1613-1618, 2012.
17. Thijssen S, Usvyat L, Kotanko P: Prediction of mortality in the first two years of hemodialysis: Results from a validation study. Blood Purif 33: 165-170, 2012.
18. Levey AS, Bosch JP, Lewis J.B., Greene T., Rogers N, Roth D: A more accurate method to estimate glomerular filtration rate from serum creatinine: A new prediction equation. Modification of Diet in Renal Disease Study Group. Ann Intern Med 130: 461-470, 1999. (Pubitemid 29135798)
19. Hecking M, Karaboyas A, Saran R., et al.: Dialysate sodium concentration and the association with interdialytic weight gain, hospitalization, and mortality. Clin J Am Soc Nephrol 7: 92-100, 2012.