Association between FAT gene and schizophrenia in the Korean population

Clinical Psychopharmacology and Neuroscience

Volumn 11, Issue 2, 2013, Pages 67-71

  Jung, Young Eun ^a,b   Jun, Tae Youn ^a  

^a The Catholic University of Korea   (South Korea)

^b Chonbuk National University   (South Korea)

Author keywords

Association; Cadherins; Korean; Polymorphism; Schizophrenia

Indexed keywords

ARTICLE; CONTROLLED STUDY; FAT GENE; FEMALE; GENE; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; SCHIZOPHRENIA; SINGLE NUCLEOTIDE POLYMORPHISM; SOUTH KOREA;

EID: 84883648074     PISSN: 17381088     EISSN: 20934327     Source Type: Journal    
DOI: 10.9758/cpn.2013.11.2.67     Document Type: Article

References (17)

1. Halliday GM. A review of the neuropathology of schizophrenia. Clin Exp Pharmacol Physiol 2001;28:64-65.
2. Weinberger DR. From neuropathology to neurodevelopment. Lancet 1995;346:552-557.
3. Brusés JL. Cadherin-mediated adhesion at the interneuronal synapse. Curr Opin Cell Biol 2000;12:593-597.
4. Huntley GW, Gil O, Bozdagi O. The cadherin family of cell adhesion molecules: multiple roles in synaptic plasticity. Neuroscientist 2002;8:221-233. (Pubitemid 34538790)
5. Shapiro L, Colman DR. The diversity of cadherins and implications for a synaptic adhesive code in the CNS. Neuron 1999;23:427-430. (Pubitemid 29359914)
6. Yagi T, Takeichi M. Cadherin superfamily genes: functions, genomic organization, and neurologic diversity. Genes Dev 2000;14:1169-1180. (Pubitemid 30327498)
7. Abou Jamra R, Becker T, Georgi A, Feulner T, Schumacher J, Stromaier J, et al. Genetic variation of the FAT gene at 4q35 is associated with bipolar affective disorder. Mol Psychiatry 2008;13:277-284. (Pubitemid 351272659)
8. Blair IP, Chetcuti AF, Badenhop RF, Scimone A, Moses MJ, Adams LJ, et al. Positional cloning, association analysis and expression studies provide convergent evidence that the cadherin gene FAT contains a bipolar disorder susceptibility allele. Mol Psychiatry 2006;11:372-383.
9. McInnis MG, Lan TH, Willour VL, McMahon FJ, Simpson SG, Addington AM, et al. Genome-wide scan of bipolar disorder in 65 pedigrees: supportive evidence for linkage at 8q24, 18q22, 4q32, 2p12, and 13q12. Mol Psychiatry 2003;8:288-298. (Pubitemid 36712922)
10. Willour VL, Zandi PP, Huo Y, Diggs TL, Chellis JL, MacKinnon DF, et al. Genome scan of the fifty-six bipolar pedigrees from the NIMH genetics initiative replication sample: chromosomes 4, 7, 9, 18, 19, 20, and 21. Am J Med Genet B Neuropsychiatr Genet 2003;121B:21-27. (Pubitemid 37064025)
11. Bramon E, Sham PC. The common genetic liability between schizophrenia and bipolar disorder: a review. Curr Psychiatry Rep 2001;3:332-337.
12. Ivleva E, Thaker G, Tamminga CA. Comparing genes and phenomenology in the major psychoses: schizophrenia and bipolar 1 disorder. Schizophr Bull 2008;34:734-742. (Pubitemid 351957570)
13. Maier W, Höfgen B, Zobel A, Rietschel M. Genetic models of schizophrenia and bipolar disorder: overlapping inheritance or discrete genotypes? Eur Arch Psychiatry Clin Neurosci 2005;255:159-166. (Pubitemid 40922938)
14. First MB, Spitzer RL, Gibbon M, Williams JB. Structured clinical interview for DSM-IV axis I disorders-clinician version (SCID-CV). Washington, DC:American Psychiatric Press;1997.
15. Guy W. Clinical global impression. Assessment manual for psychopharmacology. Washington, DC:Department of Health Education and Welfare;1976.
16. Kay SR, Fiszbein A, Opler LA. The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophr Bull 1987;13:261-276. (Pubitemid 18039085)
17. Pae CU, Chiesa A, Mandelli L, De Ronchi D, Serretti A. No influence of FAT polymorphisms in response to aripiprazole. J Hum Genet 2010;55:32-36.