Classification of methods in transcranial Electrical Stimulation (tES) and evolving strategy from historical approaches to contemporary innovations

Journal of Neuroscience Methods

Volumn 219, Issue 2, 2013, Pages 297-311

  Guleyupoglu, Berkan ^a   Schestatsky, Pedro ^b   Edwards, Dylan ^d,e,f,g   Fregni, Felipe ^c,d   Bikson, Marom ^a  

^a City University of New York   (United States)

^b FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^c and Red Sox Foundation and Massachusetts General Hospital Home Base Program   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

^e BURKE MEDICAL RESEARCH INSTITUTE   (United States)

^f WEILL CORNELL MEDICAL COLLEGE   (United States)

^g UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

Alternating; CES; CET; Contemporary; Cranial; Direct; Dosage; EA; ECT; Electroanesthesia; Electronarcosis; Electrosleep; Electrostimulation; Electrotherapy; EN; ES; FEAST; HD tDCS; Historical; History; Interferential; Limoge; NET; Pulsed; Stimulation; TACS; TCES; TCET; TDCS; TES; TPCS; Transcerebral; Transcutaneous; TRNS

Indexed keywords

ELECTROANESTHESIA; ELECTROCONVULSIVE THERAPY; ELECTRODE; ELECTROSLEEP; ELECTROSTIMULATION; GALVANIC VESTIBULAR STIMULATION; HUMAN; NEUROELECTRIC THERAPY; POLARIZATION; PRIORITY JOURNAL; REVIEW; TRANSCEREBRAL ELECTROTHERAPY; TRANSCRANIAL ALTERNATING CURRENT STIMULATION; TRANSCRANIAL DIRECT CURRENT STIMULATION; TRANSCRANIAL ELECTRICAL STIMULATION; VESTIBULAR STIMULATION; WAVEFORM;

ALTERNATING; CES; CET; CONTEMPORARY; CRANIAL; DIRECT; DOSAGE; EA; ECT; ELECTROANESTHESIA; ELECTRONARCOSIS; ELECTROSLEEP; ELECTROSTIMULATION; ELECTROTHERAPY; EN; ES; FEAST; HD-TDCS; HISTORICAL; HISTORY; INTERFERENTIAL; LIMOGE; NET; PULSED; STIMULATION; TACS; TCES; TCET; TDCS; TES; TPCS; TRANSCEREBRAL; TRANSCUTANEOUS; TRNS;

ELECTRIC STIMULATION THERAPY; HISTORY, 20TH CENTURY; HISTORY, 21ST CENTURY; HUMANS;

EID: 84883647544     PISSN: 01650270     EISSN: 1872678X     Source Type: Journal    
DOI: 10.1016/j.jneumeth.2013.07.016     Document Type: Review

References (123)

1. Aardal A.A. A study of the Vreeland Oscillator 1920, University of Wisconsin.
2. Abrams R. Electroconvulsive therapy 2002, Oxford University Press, USA.
3. Antal A., Nitsche M.A., Kincses T.Z., Kruse W., Hoffmann K., Paulus W. Facilitation of visuo-motor learning by transcranial direct current stimulation of the motor and extrastriate visual areas in humans. European Journal of Neuroscience 2004, 19:2888-2892.
4. Antal A., Boros K., Poreisz C., Chaieb L., Terney D., Paulus W. Comparatively weak after-effects of transcranial alternating current stimulation (tACS) on cortical excitability in humans. Brain Stimulation 2008, 1:97-105.
5. Antal A., Paulus W. Investigating neurplastic changes in the human brain induced by transcranial direct (tDCS) and alternating current (tACS) stimulation methods. Clinical EEG and Neuroscience 2012, 43.
6. Arfai E., Theano G., Montagu J.D., Robin A.A. A controlled study of polarization in depression. British Journal of Psychiatry 1970, 116:433-434.
7. Auri-stim Medical and Manual Auri-stim Medical Manual NET-1000 technical specifications 2013, http://www.net1device.com/specs.htm.
8. Bai S., Loo C., Dokos S. A review of computational models of transcranial electrical stimulation. Critical Reviews in Biomedical Engineering 2013, 41:21-35.
9. Baker A.P. Brain stem polarization in the treatment of depression. South African Medical Journal 1970, 44:473-475.
10. Baker J.M., Rorden C., Fridriksson J. Using transcranial direct-current stimulation to treat stroke patients with aphasia. Stroke 2010, 41:1229-1236.
11. Bikson M., Inoue M., Akiyama H., Deans J.K., Fox J.E., Miyakawa H., et al. Effects of uniform extracellular DC electric fields on excitability in rat hippocampal slices in vitro. Journal of Physiology 2004, 558:175-190.
12. Bikson M., Datta A., Rahman A., Scaturro J. Electrode Montages for tDCS and weak transcranial electrical stimulation: role of "return" electrode's position and size. Clinical Neurophysiology 2010, 121:1976-1978.
13. Bikson M., Rahman A., Datta A. Computational models of transcranial direct current sitmulation. Clinical EEG and Neuroscience 2012, 43:179-183.
14. Bindman L.J., Lippold O.C.J., Redfearn J.W.T. The action of brief polarizing currents on the cerebral cortex of the rat (1) during current flow and (2) in the production of long-lasting after-effects. Journal of Physiology 1964, 172:369-382.
15. Bini L. Professor Bini's notes on the first electro-shock experiment. Convulsive Therapy 1995, 11:260-261.
16. Brown C.C. Electroanesthesia and electrosleep. The American Psychologist 1975, 30:402-410.
17. Bolognini N., Pascual-Leone A., Fregni F. Using non-invasive brain stimulation to augment motor training-induced plasticity. Journal of NeuroEngineering and Rehabilitation 2009, 6:1-13.
18. Borckardt J.J., Romagnuolo J., Reeves S.T., Madan A., Frohman H., Beam W., et al. Feasibility, safety, and effectiveness of transcranial direct current stimulation for decreasing post-ERCP pain: a randomized, sham-controlled, pilot study. Gastrointestinal Endoscopy 2011, 73:1158-1164.
19. Borckardt J.J., Bikson M., Frohman H., Reeves S.T., Datta A., Bansal V., et al. A pilot study for the tolerability and effects of high-definition transcranial direct current stimulation (HD-tDCS) on pain perception. Journal of Pain 2012, 13:112-120.
20. Borckardt J.J., Reeves S.T., Robinson S.M., May J.T., Epperson T.I., Gunselman R.J., et al. Transcranial Direct Current Stimulation (tDCS) reduces postsurgical opioid consumption in Total Knee Arthroplasty (TKA). Clinical Journal of Pain 2013, [in press].
21. Brunoni A.R., Ferruci R., Bortolomasi M., Scelzo E., Boggio P.S., Fregni F., et al. Interactions between transcranial direct current stimulation (tDCS) and pharmacological interventions in the Major Depressive Episode: findings from a naturalistic study. European Psychiatry 2012, S0924-9338:114-119.
22. Brunoni A.R., Valiengo L., Baccaro A., Zanão T.A., de Oliveira J.F., Goulart A., et al. The sertraline vs electrical current therapy for treating depression clinical study: results from a factorial, randomized, controlled trial. JAMA Psychiatry 2013, 70:383-391.
23. Bystritsky A., Kerwin L., Feusner J. A pilot study of cranial electrotherapy stimulation for generalized anxiety disorder. Journal of Clinical Psychiatry 2008, 69:412-417.
24. Cano T., Morales-Quezada J.L., Bikson M., Fregni F. Methods to focalize noninvasive electrical brain stimulation: principles and future clinical development for the treatment of pain. Expert Review of Neurotherapeutics 2013, 13:465-467.
25. Caparelli-Dagquer E.M., Zimmermann T.J., Mooshagian E., Parra L.C., Rice J.K., Datta A., et al. A pilot study on effects of 4×1 High-Definition tDCS on motor cortex excitability. Conf proc IEEE eng med biol soc 2012, 735-738.
26. Chaieb L., Kovacs G., Cziraki C., Greenlee M., Paulus W., Antal A. Short-duration transcranial random noise stimulation induces blood oxygenation level dependent response attenuation in the human motor cortex. Experimental Brain Research 2009, 198:439-444.
27. Christensen P.A., Rotne M., Vedelsdal R., Jensen R., Jacobsen K., Husted C. Electroacupuncture in anesthesia for hysterectomy. British Journal of Anesthesia 1993, 71:835-838.
28. Cortes M., Black-Schaffer R.M., Edwards D.J. Transcranial magnetic stimulation as an investigative tool for motor dysfunction and recovery in stroke: an overview for neurorehabilitation clinicians. Neuromodulation 2012, 15:316-325.
29. DaSilva A.F., Volz M.S., Bikson M., Fregni F. Electrode positioning and montage in transcranial direct current stimulation. Journal of Visualized Experiments 2011, 51.
30. DaSilva A.F., Mendonca M.E., Zaghi S., Lopes M., Dossantos M.F., Spierings E.L., et al. tDCS-induced analgesia and electrical fields in pain-related neural networks in chronic migraine. Headache 2012, 52:1283-1295.
31. Datta A., Elwassif M., Battaglia F., Bikson M. Transcranial current stimulation focality using disc and ring electrode configurations: FEM analysis. Journal of Neural Engineering 2008, 5:163-174.
32. Datta A., Bansal V., Diaz J., Patel J., Reato D., Bikson M. Gyri-precise head model of transcranial direct current stimulation: improved spatial focality using a ring electrode versus conventional rectangular pad. Brain Stimulation 2009, 2:201-207.
33. Datta A., Bikson M., Fregni F. Transcranial direct current stimulation in patients with skull defects and skull plates: high-resolution computational FEM study of factors altering cortical current flow. Neuroimage 2010, 52:1268-1278.
34. Datta A., Baker J.M., Bikson M., Fridriksson J. Individualized model predicts brain current flow during transcranial direct-current stimulation treatment in responsive stroke patient. Brain Stimulation 2011, 4:169-174.
35. Datta A., Truong D., Minhas P., Parra L.C., Bikson M. Inter-Individual variation during transcranial direct current stimulation and normalization of dose using MRI-derived computational models. Frontiers in Psychiatry 2012, 3:1-8.
36. Datta A., Dmochowski J.P., Guleyupoglu B., Bikson M., Fregni F. Cranial electrotherapy stimulation and transcranial pulsed current stimulation: a computer based high-resolution modeling study. Neuroimage 2013, 65:280-287.
37. Dimitrov D.Tz., Ralev N.D. Signals and systems for electrosleep. Electronics and Electrical Engineering 2009, 5:95-98.
38. Dmochowski J.P., Datta A., Bikson M., Su Y., Parra L.C. Optimized multi-electrode stimulation increases focality and intensity at target. Journal of Neural Engineering 2011, 8:1-16.
39. Dmochowski J.P., Datta A., Huang Y., Richardson J.D., Bikson M., Fridriksson J., et al. Targeted transcranial direct current stimulation for rehabilitation after stroke. Neuroimage 2013, 75:12-19.
40. DosSantos M.F., Love T.M., Martikainen I.K., Nascimento T.D., Fregni F., Cummiford C., et al. Immediate effects of tDCS on the μ-opioid system of a chronic pain patient. Frontiers in Psychiatry 2012, 3:1-6.
41. D'Urso G., Mantovani A., Micillo M., Priori A., Muscettola G. Transcranial direct current stimulation and cognitive-behavioral therapy: evidence of a synergistic effect in treatment-resistant depression. Brain Stimulation 2013, 6:465-467.
42. Edelmuth R.C., Nitsche M.A., Battistella L., Fregni F. Why do some promising brain-stimulation devices fail the next steps of clinical development?. Expert Review of Medical Devices 2010, 7:67-97.
43. Edwards D.J., Krebs H.I., Rykman A., Zipse J., Thickbroom G.W., Mastaglia F.L., et al. Raised corticomotor excitability of M1 forearm area following anodal tDCS is sustained during robotic wrist therapy in chronic stroke. Restorative Neurology and Neuroscience 2009, 27:199-207.
44. Edwards D., Cortes M., Datta A., Minhas P., Wassermann E.M., Bikson M. Physiological and modeling evidence for focal transcranial electrical brain stimulation in humans: a basis for high-definition tDCS. Neuroimage 2013, 74:266-275.
45. Faedda G.L., Becker I., Baroni A., Tondo L., Aspland E., Koukopoulos A. The origins of electroconvulsive therapy: Prof. Bini's first report on ECT. Journal of Affective Disorders 2010, 120:12-15.
46. FDA Executive Summary Prepared for the January 27-28, 2011 meeting of the neurological panel meeting to discuss the classification of electroconvulsive therapy devices 2012.
47. Fritsch B., Reis J., Martinowich K., Schambra H.M., Ji Y., Cohen L.G., et al. Direct current stimulation promotes BDNF-dependent synaptic plasticity: potential implications for motor learning. Neuron 2010, 66:198-204.
48. Gabis L., Shklar B., Baruch Y.K., Raz R., Gabis E., Geva D. Pain reduction using transcranial electrostimulation: a double-blind "active placebo" controlled trial. Journal of Rehabilitation Medicine 2009, 41:256-261.
49. Geddes L.A., Hoft H.E., Voss C. Cardiovascular respiratory studies during electronarcosis in the dog. Cardiovascular Research Center Bulletin 1964, 3:38-47.
50. Giacobbe V., Krebs H.I., Volpe B.T., Pascual-Leone A., Rykman A., Zeirati G., et al. Transcranial direct current stimulation (tDCS) and robotic practice in chronic stroke: the dimension of timing. Neurorehabilitation 2013, [in press].
51. Gilula M.F., Kirsch D.L. Cranial electrotherapy stimulation review: a safer alternative to psychopharmaceuticals in the treatment of Depression. Journal of Neurotherapy 2005, 9:7-26.
52. Hermann R.C., Dorwart R.A., Hoover C.W., Brody J. Variation in ECT use in the United States. American Journal of Psychiatry 1995, 152:869-875.
53. Jensen M.P., Sherlin L.H., Askew R.L., Fregni F., Witkop G., Gianas A., et al. Effects of non-pharmacological pain treatments on brain states. Clinical Neurophysiology 2013, [in press].
54. Kalkman C.J., Drummond J.C., Kennelly N.A., Patel P.M., Partridge B.L. Intraoperative monitoring of tibialis anterior muscle motor evoked responses to transcranial electrical stimulation during partial neuromuscular blockade. Anesthesia and Analgesia 1992, 75:584-589.
55. Kirsch D.L. Low level brain stimulation for anxiety: a review of 50 years of research and supporting data 2010.
56. Knutson R.C., Tichy F.Y., Reitman J.R. Use of electrical current as an anesthetic agent. Anesthesiology 1956, 17:815.
57. Knutson R.C. Experiments in electronarcosis: a preliminary study. Anesthesiology 1954, 17:815-825.
58. Knutson R.C. First international symposium on electrosleep therapy and electroanesthesia. Anesthesia and Analgesia 1967, 46:333-339.
59. Kumru H., Soler D., Vidal J., Navarro X., Tormos J.M., Pascual-Leone A., et al. The effects of transcranial direct current stimulation with visual illusion in neuropathic pain due to spinal cord injury: an evoked potentials and quantitative thermal testing study. European Journal of Pain 2013, 17:55-66.
60. Kuo H.I., Bikson M., Datta A., Minhas P., Paulus W., Kuo M.F., et al. Comparing cortical plasticity induced by conventional and high-definition 4×1 ring tDCS: a neurophysiological study. Brain Stimulation 2013, 6:644-648.
61. Lang N., Siebner H.R., Ernst D., Nitsche M.A., Paulus W., Lemon R.N., et al. Preconditioning with transcranial Direct Current Stimulation sensitizes the motor cortex to rapid-rate transcranial magnetic stimulation and controls the direction of after effects. Biological Psychiatry 2004, 56:634-639.
62. Laste G., Caumo W., Adachi L.N., Rozisky J.R., de Macedo I.C., Filho P.R., et al. After-effects of consecutive sessions of transcranial direct current stimulation (tDCS) in a rat model of chronic inflammation. Experimental Brain Research 2012, 221:75-83.
63. Li F., Tsien J.Z. Memory and the NMDA receptors. New England Journal of Medicine 2009, 361:302-303.
64. Limoge A., Robert C., Stanley T.H. Transcutaneous cranial electrical stimulation (TCES): a review 1998. Neuroscience and Biobehavioral Reviews 1999, 23:529-538.
65. Lisanby S.H. Electroconvulsive therapy for depression. New England Journal of Medicine 2007, 357:1939-1945.
66. Liss Body Stimulator Manual(B), Bipolar Model No. SBL-502-B Manual 480.
67. Liss Body Stimulator Manual(M), Monopolar Model No. SBL-501-M Manual.
68. Liss Stimulators Application Notes - Monopolar/Bipolar; 1991. p. 1-3.
69. Macdonald D.B. Safety of intraoperative transcranial electrical stimulation motor evoked potential monitoring. Journal of Clinical Neurophysiology 2002, 19:416-429.
70. Martin D.M., Liu R., Alonzo A., Green M., Player M.J., Sachdev P., et al. Can transcranial direct current stimulation enhance outcomes from cognitive training?. A randomized controlled trial in healthy participants. International Journal of Neuropsychopharmacology 2013, 1-10. [in press].
71. Marquez-Ruis J., Leal-Campanario R., Sanchez-Campusano R., Molaee-Ardekani B., Wendling F., Miranda P.C., et al. Transcranial direct-current stimulation modulates synaptic mechanisms involved in associative learning in behaving rabbits. Proceedings of the National Academy of Sciences of the United States of America 2012, 109:6710-6715.
72. Marshall L., Helgadottir H., Molle M., Born J. Boosting slow oscillations during sleep potentiates memory. Nature 2006, 444:610-613.
73. Marshall L., Kirov R., Brade J., Molle M., Born J. Transcranial electrical currents to probe EEG brain rhythms and memory consolidation during sleep in humans. PLoS ONE 2011, 6:1-10.
74. Merrill D., Bikson M., Jefferys J.G.R. Electrical stimulation of excitable tissue: design of efficacious and safe protocols. Journal of Neuroscience Methods 2005, 141:171-198.
75. Merton P.A., Morton H.B. Stimulation of the cerebral cortex in the intact human subject. Nature 1980, 285:227.
76. Miller S.M., Ngo T.T. Studies of Caloric Vestibular Stimulation: implications for the cognitive neurosciences, the clinical neurosciences and neurophysiology. Acta Neuropsychiatrica 2007, 19:183-203.
77. Minhas P., Bansal V., Patel J., Ho J.S., Diaz J., Datta A., et al. Electrodes for high-definition transcutaneous DC stimulation for applications in drug delivery and electrotherapy, including tDCS. Journal of Neuroscience Methods 2010, 190(2):188-197.
78. Mylius V., Borckardt J.J., Lefaucheur J.P. Noninvasive cortical modulation of experimental pain. Pain 2012, 153:1350-1363.
79. Nair D.G., Renga B., Lindenberg R., Zhu L., Schlaug G. Optimizing recovery potential through simultaneous occupational therapy and non-invasive brain-stimulation using tDCS. Restorative Neurology and Neuroscience 2011, 29:411-420.
80. Nekhendzy V., Lemmens H.J., Tingle M., Nekhendzy M., Angst M.S. The analgesic and antihyperalgesic effects of transcranial electrostimulation with combined direct and alternating current in healthy volunteers. Anesthesia and Analgesia 2010, 111:1301-1307.
81. NET Device Corp Information AboutNET 2013, http://www.netdevice.net/aboutnet.php.
82. Nias D.K., Shapiro M.B. The effects of small electrical currents upon depressive symptoms. British Journal of Psychiatry 1974, 125:414-415.
83. Nitsche M.A., Paulus W. Excitability changes induced in the human motor cortexes by weak transcranial direct current stimulation. Journal of Physiology 2000, 527:633-639.
84. Nitsche M.A., Doemkes S., Karakose T., Antal A., Liebetanz D., Lang N., et al. Shaping the effects of transcranial direct current stimulation of the human motor cortex. Journal of Neurophysiology 2007, 97:3109-3117.
85. Nitsche M.A., Paulus W. Transcranial direct current stimulation-update 2011. Restorative Neurology and Neuroscience 2011, 29:463-492.
86. Obrosow A.N. Electro-sleep therapy. Therapeutic electricity and ultraviolet radiation 1959, Editor, New Haven, CT. E. Licht (Ed.).
87. Olfson M., Marcus S., Sackeim H.A., Thompson J., Pincus H.A. Use of ECT for the inpatient treatment of recurrent major depression. American Journal of Psychiatry 1998, 155:22-29.
88. Patterson M.A. Effects of Neuro-Electric Therapy (N.E.T.) in drug addiction: interim report. Bulletin on Narcotics 1976, 28(4):55-62.
89. Patterson M.A. Electrotherapy: addictions and neuroelectric therapy. Nursing Times 1979, 75(48):2080-2083.
90. Paulus W. Transcranial electrical stimulation (tES - tDCS; tRNS, tACS) methods. Neuropsychological Rehabilitation 2011, 21:602-617.
91. Perera T. Telegraph and scientific instrument museum 2013, http://www.w1tp.com/.
92. Peterchev A.V., Wagner T.A., Miranda P.C., Nitsche M.A., Paulus W., Lisanby S.H., et al. Fundamentals of transcranial electric and magnetic stimulation dose: definition, selection and reporting practices. Brain Stimulation 2012, 5:435-453.
93. Priori A., Berardelli A., Rona S., Accornero N., Manfredi M. Polarization of the human motor cortex through the scalp. Neuro Report 1998, 9:2257-2260.
94. Radman T., Ramos R.L., Brumberg J.C., Bikson M. Role of cortical cell type and morphology in subthreshold and suprathreshold uniform electric field stimulation in vitro. Brain Stimulation 2009, 2:215-228.
95. Rahman A., Reato D., Arlotti M., Gasca F., Datta A., Parra L.C., et al. Cellular effects of acute direct current stimulation: somatic and synaptic terminal effects. Journal of Physiology 2013, 591:2563-2578.
96. Ramsay J.C., Schlagenhauf G. Treatment of depression with low voltage direct current. Southern Medical Journal 1966, 59:932-934.
97. Redfearn J.W.T., Lippold O.C.J., Costain R. Preliminary account of the clinical effects of polarizing the brain in certain psychiatric disorders. The British Journal of Psychiatry 1964, 110:773-785.
98. von Richthofen C.L., Mellor C.S. Cerebral electrotherapy: methodological problems in assessing its therapeutic effectiveness. Psychological Bulletin 1979, 86:1264-1271.
99. Robinovitch L.G. Electrical analgesia, sleep and resuscitation. Anesthesia 1914, Appleton, New York. J.T. Gwathmey (Ed.).
100. Rothwell J., Burke D., Hicks R., Stephen J., Woodforth I., Crawford M. Transcranial electrical stimulation of the motor cortex in man: further evidence for the site of activation. Journal of Physiology 1994, 481:243-250.
101. Rosa M.A., Lisanby S.H. Somatic treatments for mood disorders. Neuropsychopharmacology 2012, 37:102-116.
102. Rossini P.M., Marciani M.G., Caramia M., Roma V., Zarola F. Nervous Propagation along 'central' motor pathways in intact man: characteristics of motor responses to 'bifocal' and 'unifocal' spine and scalp non-invasive stimulation. Electroencephalography and Clinical Neurophysiology 1985, 61:272-286.
103. Rudorfer M.V., Henry M.E., Sackeim H.A. Electroconvulsive therapy. Psychiatry 1997, vol. 2. W.B. Saunders Co, Philadelphia.
104. Rush S., Driscoll D.A. Current distribution in the brain from surface electrodes. Anesthesia and Analgesia 1968, 47:717-723.
105. Rush A.J., Trivedi M.H., Wisniewski S.R., Nierenberg A.A., Stewart J.W., Warden D., et al. Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: a STARD report. American Journal of Psychiatry 2006, 163:1905-1917.
106. Sackeim H.A., Prudic J., Devanand D.P., Nobler M.S., Lisanby S.H., Peyser S., et al. A Prospective, randomized, double-blind comparison of bilateral and right unilateral electroconvulsive therapy at different stimulus intensities. Archives of General Psychiatry 2000, 57:425-434.
107. Sances A., Larson S.J., Hause L.L. A neuron model for electroanesthesia. Proceedings of the 2nd international symposium on electrosleep and electroanesthesia, vol. 2 1969, 306-314.
108. Schutter D.J., Hortensius R. Brain oscillations and frequency-dependant modulation of cortical excitability. Brain Stimulation 2011, 4:97-103.
109. Shelyakin A., Preobrazhenskaya I. Principles of the weak direct current therapy 2009, https://sites.google.com/site/micropolarization/principles.
110. Smith R.B. Cranial electrotherapy stimulation: its first fifty years, plus three 2006.
111. Smith R.H., Tatsuno J., Zouhar R.L. Electroanesthesia: a review - 1966. Anesthesia and Analgesia 1967, 46:109-125.
112. Smith R.H., Andrew J.H., Suzuki H., Tatsuno J. Electroanesthesia studies: a new current patter and control of fading. Anesthesia and Analgesia 1968, 47:627-632.
113. Smith R.H. Electroanesthesia (EA), 1971. Anesthesiology 1971, 34:60-72.
114. Spellman T., Peterchev A.V., Lisanby S.H. Focal electrically administered seizure therapy: a novel form of ECT illustrates the roles of current directionality, polarity, and electrode configuration in seizure induction. Neuropsychopharmacology 2009, 34:2002-2010.
115. Spezia Adachi L.N., Canumo W., Laste G., Fernandes Medeiros L., Ripoll Rozisky J., de Souza A., et al. Reversal of chronic stress-induced pain by transcranial direct current stimulation (tDCS) in an animal model. Brain Research 2012, 1489:17-26.
116. Torres J., Drebing D., Hamilton R. TMS and tDCS in post-stroke aphasia: integrating novel treatment approaches with mechanisms of plasticity. Restorative Neurology and Neuroscience 2013, 31:501-515.
117. Truong D.Q., Magerowski G., Pascual-Leone A., Alonso-Alonso M., Bikson M. Finite element study of skin and fat delineation in an obese subject for transcranial Direct Current Stimulation. Conf proc IEEE eng med biol soc 2012, 6587-6590.
118. Turkeltaub P.E., Benson J., Hamilton R.H., Datta A., Bikson M., Coslett H.B. Left lateralizing transcranial direct current stimulation improves reading efficiency. Brain Stimulation 2012, 5:201-207.
119. Watson S.R.D., Colebatch J.G. EMG responses in the soleus muscles evoked by unipolar galvanic vestibular stimulation. Electroencephalography and clinical Neurophysiology 1997, 105:476-483.
120. Wagner T., Fregni F., Fecteau S., Grodzinsky A., Zahn M., Pascual-Leone A. Transcranial direct current stimulation: a computer-based human model study. Neuroimage 2007, 35:1113-1124.
121. Zaehle T., Rach S., Herrmann C.S. Transcranial alternating current stimulation enhances individual alpha activity in human EEG. PLoS ONE 2010, 5:1-7.
122. Zaghi S., Thiele B., Pimentel D., Pimentel T., Fregni F. Assessment and treatment of pain with non-invasive cortical stimulation. Restorative Neurology and Neuroscience 2011, 29:439-451.
123. Zentner J., Kiss I., Ebner A. Influence of anesthetics-nitrous oxide in particular-on electromyographic response evoked by transcranial electrical stimulation of the cortex. Neurosurgery 1989, 24:253-256.