Effect of simulated obstructive hypopnea and apnea on thoracic aortic wall transmural pressures

Journal of Applied Physiology

Volumn 115, Issue 5, 2013, Pages 613-617

  Clarenbach, Christian F ^a   Camen, Giovanni ^a   Sievi, Noriane A ^a   Wyss, Christophe ^a   Stradling, John R ^b   Kohler, Malcolm ^a,c  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b CHURCHILL HOSPITAL   (United Kingdom)

^c UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Aortic dilatation; Obstructive sleep apnea; Transmural aortic pressure

Indexed keywords

AGED; AORTA DILATATION; ARTICLE; BLOOD PRESSURE; BREATHING; ESOPHAGUS; HUMAN; MALE; MIDDLE AGED; PATHOPHYSIOLOGY; PHYSIOLOGY; RISK FACTOR; SLEEP DISORDERED BREATHING; THORACIC AORTA; TRANSMURAL AORTIC PRESSURE;

AORTIC DILATATION; OBSTRUCTIVE SLEEP APNEA; TRANSMURAL AORTIC PRESSURE;

AGED; AORTA, THORACIC; BLOOD PRESSURE; ESOPHAGUS; HUMANS; MALE; MIDDLE AGED; RESPIRATION; RISK FACTORS; SLEEP APNEA, OBSTRUCTIVE;

EID: 84883574899     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00439.2013     Document Type: Article

References (17)

1. Baguet JP, Minville C, Tamisier R, Roche F, Barone-Rochette G, Ormezzano O, Levy P, Pepin JL. Increased aortic root size is associated with nocturnal hypoxia and diastolic blood pressure in obstructive sleep apnea. Sleep 34: 1605-1607, 2011.
2. Chen RC, Que CL, Yan S. Introduction to a new inspiratory threshold loading device. Eur Respir J 12: 208-211, 1998.
3. Guo DC, Papke CL, He R, Milewicz DM. Pathogenesis of thoracic and abdominal aortic aneurysms. Ann NY Acad Sci 1085: 339-352, 2006.
4. Haentjens P, Van Meerhaeghe A, Moscariello A, De Weerdt S, Poppe K, Dupont A, Velkeniers B. The impact of continuous positive airway pressure on blood pressure in patients with obstructive sleep apnea syndrome: evidence from a meta-analysis of placebo-controlled randomized trials. Arch Intern Med 167: 757-764, 2007.
5. Kohler M, Blair E, Risby P, Nickol AH, Wordsworth P, Forfar C, Stradling JR. The prevalence of obstructive sleep apnoea and its association with aortic dilatation in Marfan's syndrome. Thorax 64: 162-166, 2009.
6. Kohler M, Pitcher A, Blair E, Risby P, Senn O, Forfar C, Wordsworth P, Stradling JR. The impact of obstructive sleep apnea on aortic disease in Marfan's Syndrome. Respiration (September 20, 2012). doi:10.1159/ 000340008.
7. Kohler M, Stradling JR. Mechanisms of vascular damage in obstructive sleep apnea. Nat Rev Cardiol 7: 677-685, 2010.
8. Lee LC, Torres MC, Khoo SM, Chong EY, Lau C, Than Y, Shi DX, Kailasam A, Poh KK, Lee CH, Yeo TC. The relative impact of obstructive sleep apnea and hypertension on the structural and functional changes of the thoracic aorta. Sleep 33: 1173-1176, 2010.
9. Magder SA, Lichtenstein S, Adelman AG. Effect of negative pleural pressure on left ventricular hemodynamics. Am J Cardiol 52: 588-593, 1983.
10. Marin JM, Carrizo SJ, Vicente E, Agusti AG. Long-term cardiovascular outcomes in men with obstructive sleep apnoea-hypopnoea with or without treatment with continuous positive airway pressure: an observational study. Lancet 365: 1046-1053, 2005.
11. Mason RH, Ruegg G, Perkins J, Hardinge M, Amann-Vesti B, Senn O, Stradling JR, Kohler M. Obstructive sleep apnea in patients with abdominal aortic aneurysms: highly prevalent and associated with aneurysm expansion. Am J Respir Crit Care Med 183: 668-674, 2011.
12. Orban M, Bruce CJ, Pressman GS, Leinveber P, Romero-Corral A, Korinek J, Konecny T, Villarraga HR, Kara T, Caples SM, Somers VK. Dynamic changes of left ventricular performance and left atrial volume induced by the mueller maneuver in healthy young adults and implications for obstructive sleep apnea, atrial fibrillation, and heart failure. Am J Cardiol 102: 1557-1561, 2008.
13. Peters J, Kindred MK, Robotham JL. Transient analysis of cardiopulmonary interactions. I Diastolic events J Appl Physiol 64: 1506-1517, 1988.
14. Peters J, Kindred MK, Robotham JL. Transient analysis of cardiopulmonary interactions. II Systolic events J Appl Physiol 64: 1518-1526, 1988.
15. Serizawa N, Yumino D, Takagi A, Gomita K, Kajimoto K, Tsurumi Y, Hagiwara N. Obstructive sleep apnea is associated with greater thoracic aortic size. J Am Coll Cardiol 52: 885-886, 2008.
16. Stoewhas AC, Namdar M, Biaggi P, Russi EW, Bloch KE, Stradling JR, Kohler M. The effect of simulated obstructive apnea and hypopnea on aortic diameter and BP. Chest 140: 675-680, 2011.
17. Warley AR, Fontes F, Wilson M, Raine AE, Stradling JR. Lack of effect of an inspiratory threshold load on plasma atrial natriuretic peptide levels. Clin Sci (Lond) 78: 311-313, 1990.