Maternal molecular features and gene profiling of monocytes during first trimester pregnancy

Journal of Reproductive Immunology

Volumn 99, Issue 1-2, 2013, Pages 62-68

  Koldehoff, Michael ^a   Cierna, Barbara ^b   Steckel, Nina K ^a   Beelen, Dietrich W ^a   Elmaagacli, Ahmet H ^a  

^a UNIVERSITY HOSPITAL ESSEN   (Germany)

^b HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Gene expression; Microarray analysis; Pregnancy

Indexed keywords

CD14 ANTIGEN; CD200 ANTIGEN; CD200 RECEPTOR; GAMMA INTERFERON INDUCIBLE PROTEIN 10; HLA DRB4 ANTIGEN; INHIBITOR OF DIFFERENTIATION 1; INHIBITOR OF DIFFERENTIATION 2; INTERLEUKIN 10; INTERLEUKIN 8; OLIGONUCLEOTIDE; RANTES; SUPPRESSOR OF CYTOKINE SIGNALING 1; TRANSCRIPTION FACTOR;

ADULT; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; FEMALE; FIRST TRIMESTER PREGNANCY; FLOW CYTOMETRY; GENE EXPRESSION; GENE TARGETING; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; IMMUNOCOMPETENT CELL; IMMUNOREGULATION; MICROARRAY ANALYSIS; MONOCYTE; MOTHER FETUS RELATIONSHIP; NORMAL HUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION;

GENE EXPRESSION; MICROARRAY ANALYSIS; PREGNANCY;

ADULT; ANTIGENS, CD; ANTIGENS, CD14; CELLS, CULTURED; CYTOKINES; FEMALE; GENE EXPRESSION PROFILING; HUMANS; IMMUNITY; IMMUNOMODULATION; INDOLEAMINE-PYRROLE 2,3,-DIOXYGENASE; INHIBITOR OF DIFFERENTIATION PROTEIN 1; INHIBITOR OF DIFFERENTIATION PROTEIN 2; MICROARRAY ANALYSIS; MONOCYTES; PREGNANCY; PREGNANCY TRIMESTER, FIRST; SIGNAL TRANSDUCTION; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; TRANSCRIPTION, GENETIC;

EID: 84883560831     PISSN: 01650378     EISSN: 18727603     Source Type: Journal    
DOI: 10.1016/j.jri.2013.07.001     Document Type: Article

References (30)

1. Allen S.J., Crown S.E., Handel T.M. Chemokines: receptor structure, interactions, and antagonism. Annu. Rev. Immunol. 2007, 25:787-820.
2. Amarnath S., Mangus C.W., Wang J.C., Wei F., He A., Kapoor V., et al. The PDL1-PD1 axis converts human TH1 cells into regulatory T cells. Sci. Transl. Med. 2011, 3:111ra120.
3. Basu S., Leahy P., Challier J.C., Minium J., Catalano P., Hauguel-de Mouzon S. Molecular phenotype of monocytes at the maternal-fetal interface. Am. J. Obstet. Gynecol. 2011, 205:e1-e8. 265.
4. Beissbarth T., Speed T.P. GOstat: find statistically overrepresented gene ontologies within a group of genes. Bioinformatics 2004, 20:1464-1465.
5. Billingham R.E. Transplantation immunity and the maternal-fetal relation. N. Engl. J. Med. 1964, 270:667-672.
6. Cristillo A.D., Heximer S.P., Russell L., Forsdyke D.R. Cyclosporin A inhibits early mRNA expression of G0/G1 switch gene 2 (G0S2) in cultured human blood mononuclear cells. DNA Cell Biol. 1997, 16:1449-1458.
7. Giulietti A., van Etten E., Overbergh L., Stoffels K., Bouillon R., Mathieu C. Monocytes from type 2 diabetic patients have a pro-inflammatory profile 1,25-dihydroxyvitamin D(3) works as anti-inflammatory. Diabetes Res. Clin. Pract. 2007, 77:47-57.
8. Gorczynski R.M. CD200 and its receptors as targets for immunoregulation. Curr. Opin. Investig. Drugs 2005, 6:483-488.
9. Hornung V., Rothenfusser S., Britsch S., Krug A., Jahrsdörfer B., Giese T., et al. Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides. J. Immunol. 2002, 168:4531-4537.
10. Jiang S.P., Vacchio M.S. Multiple mechanisms of peripheral T cell tolerance to the fetal "allograft". J. Immunol. 1998, 160:3086-3090.
11. Kim S.Y., Romero R., Tarca A.L., Bhatti G., Kim C.J., Lee, et al. Methylome of fetal and maternal monocytes and macrophages at the feto-maternal interface. Am. J. Reprod. Immunol. 2012, 68:8-27.
12. Koga K., Mor G. Toll-like receptors at the maternal-fetal interface in normal pregnancy and pregnancy disorders. Am. J. Reprod. Immunol. 2010, 63:587-600.
13. Koldehoff M., Zakrzewski J.L., Klein-Hitpass L., Beelen D.W., Elmaagacli A.H. Gene profiling of growth factor independence 1B gene (Gfi-1B) in leukemic cells. Int. J. Hematol. 2008, 87:39-47.
14. Koldehoff M., Katzorke T., Wisbrun N.C., Propping D., Wohlers S., Bielfeld P., et al. Modulating impact of human chorionic gonadotropin hormone on the maturation and function of hematopoietic cells. J. Leukoc. Biol. 2011, 90:1017-1026.
15. Koldehoff M., Elmaagacli A.H. Thoughts on feto-maternal tolerance: is there a lesson to be learned from allogeneic haematopoietic stem cell transplantation?. Cell Biol. Int. 2013, 37:766-767.
16. Langat D.L., Wheaton D.A., Platt J.S., Sifers T., Hunt J.S. Signaling pathways for B cell-activating factor (BAFF) and a proliferation-inducing ligand (APRIL) in human placenta. Am. J. Pathol. 2008, 172:1303-1311.
17. Nancy P., Tagliani E., Tay C.S., Asp P., Levy D.E., Erlebacher A. Chemokine gene silencing in decidual stromal cells limits T cell access to the maternal-fetal interface. Science 2012, 336:1317-1321.
18. Neuteboom R.F., Janssens A.C., Siepman T.A., Hoppenbrouwers I.A., Ketelslegers I.A., et al. Pregnancy in multiple sclerosis: clinical and self-report scales. J. Neurol. 2012, 259:311-317.
19. Pappas C.T., Bliss K.T., Zieseniss A., Gregorio C.C. The Nebulin family: an actin support group. Trends Cell Biol. 2011, 21:29-37.
20. Phillips T.A., Ni J., Hunt J.S. Cell-specific expression of B lymphocyte (APRIL, BLyS)- and Th2 (CD30L/CD153)-promoting tumor necrosis factor superfamily ligands in human placentas. J. Leukoc. Biol. 2003, 74:81-87.
21. Raghupathy R., Al-Azemi M., Azizieh F. Intrauterine growth restriction: cytokine profiles of trophoblast antigen-stimulated maternal lymphocytes. Clin. Dev. Immunol. 2012, 2012:734865.
22. Renaud S.J., Graham C.H. The role of macrophages in utero-placental interactions during normal and pathological pregnancy. Immunol. Investig. 2008, 37:535-564.
23. Sacks G., Sargent I., Redman C. An innate view of human pregnancy. Immunol. Today 1999, 20:114-118.
24. Stout R.D., Watkins S.K., Suttles J. Functional plasticity of macrophages: in situ reprogramming of tumor-associated macrophages. J. Leukoc. Biol. 2009, 86:1105-1109.
25. Sun L., Ye R.D. Role of G protein-coupled receptors in inflammation. Acta Pharmacol. Sin. 2012, 33:342-350.
26. Thaxton J.E., Sharma S. Interleukin-10: a multi-faceted agent of pregnancy. Am. J. Reprod. Immunol. 2010, 63:482-491.
27. Walker D.G., Dalsing-Hernandez J.E., Campbell N.A., Lue L.F. Decreased expression of CD200 and CD200 receptor in Alzheimer's disease: a potential mechanism leading to chronic inflammation. Exp. Neurol. 2009, 215:5-19.
28. Wan H., Versnel M.A., Leijten L.M., van Helden-Meeuwsen C.G., Fekkes D., Leenen P.J., et al. Chorionic gonadotropin induces dendritic cells to express a tolerogenic phenotype. J. Leuk. Biol. 2008, 83:894-901.
29. Wright G.J., Cherwinski H., Foster-Cuevas M., Brooke G., Puklavec M.J., Bigler M., et al. Characterization of the CD200 receptor family in mice and humans and their interactions with CD200. J. Immunol. 2003, 171:3034-3046.
30. Zhang J., Gong Y., Yu Y. PG F(2α) receptor: a promising therapeutic target for cardiovascular disease. Front. Pharmacol. 2010, 1:116.