Benign hepatocellular nodules: What have we learned using the patho-molecular classification

Clinics and Research in Hepatology and Gastroenterology

Volumn 37, Issue 4, 2013, Pages 322-327

  Sempoux, Christine ^a   Chang, Charissa ^b   Gouw, Annette ^c   Chiche, Laurence ^d   Zucman Rossi, Jessica ^e,f,g   Balabaud, Charles ^h   Bioulac Sage, Paulette ^h,i  

^a CLINIQUES UNIVERSITAIRES SAINT LUC   (Belgium)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^d BORDEAUX UNIVERSITY HOSPITAL   (France)

^e INSERM   (France)

^f UNIVERSITÉ PARIS DESCARTES   (France)

^g ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

^h UNIVERSITÉ DE BORDEAUX   (France)

ⁱ HÔpital Pellegrin ^*  (France)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; C REACTIVE PROTEIN; HEPATOCYTE NUCLEAR FACTOR 1ALPHA;

ADENOMATOSIS; ARTIFICIAL EMBOLISM; BLEEDING; CLINICAL EVALUATION; DIFFERENTIAL DIAGNOSIS; DISEASE CLASSIFICATION; GENDER; GENE MUTATION; GENETIC DISORDER; GLYCOGEN STORAGE DISEASE; GOOD CLINICAL PRACTICE; HEPATOCELLULAR ADENOMA; HUMAN; IMMUNOHISTOCHEMISTRY; LIVER ADENOMA; LIVER BIOPSY; LIVER CELL CARCINOMA; LIVER NODULE; MALIGNANT TRANSFORMATION; NODULAR HYPERPLASIA; NON INVASIVE PROCEDURE; NUCLEAR MAGNETIC RESONANCE IMAGING; ONCOGENE; PHENOTYPE; PRACTICE GUIDELINE; RISK ASSESSMENT; SHORT SURVEY; VASCULAR DISEASE;

ADENOMA, LIVER CELL; HUMANS;

EID: 84883555150     PISSN: 22107401     EISSN: 2210741X     Source Type: Journal    
DOI: 10.1016/j.clinre.2013.04.008     Document Type: Short Survey

References (33)

1. Bioulac-Sage P., Rebouissou S., Thomas C., Blanc J.F., Saric J., Sa Cunha A., et al. Hepatocellular adenoma subtype classification using molecular markers and immunohistochemistry. Hepatology 2007, 46:740-748.
2. Bioulac-Sage P., Laumonier H., Balabaud C. Benign hepatocellular tumors. Practical Hepatic Pathology: A Diagnostic Approach 2010, 373-488. Saunders, Philadelphia. R. Saxena (Ed.).
3. Bioulac-Sage P., Balabaud C., Wanless I. Focal nodular hyperplasia and hepatocellular adenoma. Tumors of the Digestive Tract 2010, 198-204. World Health Organization, IARC, Lyon, France. F. Bosman, F. Carneiro, R. Hruban, N.D. Theise (Eds.).
4. Bioulac-Sage P., Cubel G., Balabaud C., Zucman-Rossi J. Revisiting the pathology of resected benign hepatocellular nodules using new immunohistochemical markers. Semin Liver Dis 2011, 31:91-103.
5. Bioulac-Sage P., Cubel G., Balabaud C. Pathological diagnosis of hepatocellular adenoma in clinical practice. Diagn Histopathol 2011, 17:521-529.
6. Van der Borght S., Libbrecht L., Katoonizadeh A., Aerts R., Nevens F., Verslype C., Roskams T.A. Nuclear beta-catenin staining and absence of steatosis are indicators of hepatocellular adenomas with an increased risk of malignancy. Histopathology 2007, 51:855-856.
7. Sasaki M., Yoneda N., Kitamura S., Sato Y., Nakanuma Y. Characterization of hepatocellular adenoma based on the phenotypic classification: the Kanazawa experience. Hepatol Res 2011, 41:982-988.
8. Van Aalten S.M., Verheij J., Terkivatan T., Dwarkasing R.S., de Man R.A., Ijzermans J.N. Validation of a liver adenoma classification system in a tertiary referral centre: implications for clinical practice. J Hepatol 2011, 55:120-125.
9. Bellamy C.O.C., Maxwell R.S., Prost S., Azodo I.A., Powell J.J., Manning J.R. The value of imunophenotyping hepatocellular adenomas-consecutive resections at one UK centre. Histopathology 2012-2013, 62:431-445.
10. Han J., van den Heuvel M.C., Kusano H., de Jong K.P., Gouw A.S. How normal is the liver in which the inflammatory type hepatocellular adenoma develops?. Int J Hepatol. 2012, 805621.
11. Chang C., Thung S.N., Roayaie S., Schwartz M.E., Hernandez-Prera J.C. Changing epidemiology of hepatocellular adenoma in the United States: review of the literature. Int J Hepatol 2013, 604860.
12. Fonseca S., Hoton D., Dardenne S., Annet L., Hubert C., Godecharles S., et al. Revision of hepatocellular adenomas according to The Bordeaux Criteria: a learning experience. Int J Hepatol 2013, 398308.
13. Bioulac-Sage P., Laumonier H., Rullier A., Cubel G., Laurent C., Zucman-Rossi J., Balabaud C. Over-expression of glutamine synthetase in focal nodular hyperplasia: a novel easy diagnostic tool in surgical pathology. Liver Int 2009, 29:459-465.
14. Bioulac-Sage P., Cubel G., Taouji S., Scoazec J.Y., Leteurtre E., Paradis V., et al. Immunohistochemical markers on needle biopsies are helpful for the diagnosis of focal nodular hyperplasia and hepatocellular adenoma subtypes. Am J Surg Pathol 2012, 36:1691-1699.
15. Laumonier H., Bioulac-Sage P., Laurent C., et al. Hepatocellular adenomas: magnetic resonance imaging features as a function of molecular pathological classification. Hepatology 2008, 48:808-818.
16. Laumonier H., Cailliez H., Balabaud C., Possenti L., Zucman-Rossi J., Bioulac-Sage P., Trillaud H. Role of contrast-enhanced sonography in differentiation of subtypes of hepatocellular adenoma: correlation with MRI findings. AJR Am J Roentgenol 2012, 199:341-348.
17. Van Aalten S.M., Thomeer M.G., Terkivatan T., Dwarkasing R.S., Verheij J., de Man R.A., Ijzermans J.N. Hepatocellular adenomas: correlation of MR imaging findings with pathologic subtype classification. Radiology 2011, 261:172-181.
18. Ronot M., Bahrami S., Calderaro J., et al. Hepatocellular adenomas: accuracy of magnetic resonance imaging and liver biopsy in subtype classification. Hepatology 2011, 53:1182-1191.
19. Manichon A.F., Bancel B., Durieux-Millon M., et al. Hepatocellular adenoma: evaluation with contrast-enhanced ultrasound and MRI and correlation with pathologic and phenotypic classification in 26 lesions. HPB Surg 2012, 418745.
20. Bioulac-Sage P., Taouji S., Le Bail B., Possenti L., Balabaud C. Value and limits of routine histology alone or combined with glutamine synthetase immunostaining in the diagnosis of hepatocellular adenoma subtypes on surgical specimens. Int J Hepatol 2013, 2013:417323.
21. Nault J.C., Bioulac-Sage P., Zucman-Rossi J. Hepatocellular benign tumors: from molecular to personalized clinical care. Gastroenterology 2013, 144:888-902. [Epub ahead of print].
22. Bioulac-Sage P., Taouji S., Possenti L., Balabaud C. Hepatocellular adenoma subtypes: the impact of overweight and obesity. Liver Int 2012, 32:1217-1221.
23. Zucman-Rossi J., Jeannot E., Nhieu J.T., Scoazc J.Y., Guettier C., Rebouissou S., et al. Genotype-phenotype correlation in hepatocellular adenoma: new classification and relationship with HCC. Hepatology 2006, 43:515-524.
24. Stoot J.H., Coelen R.J., De Jong M.C., De Jong C.H. Malignant transformation of hepatocellular adenomas into hepatocellular carcinomas: a systematic review including more than 1600 adenoma cases. HPB (Oxford) 2010, 12:509-522.
25. Farges O., Ferreira N., Dokmak S., Belghiti J., Bedossa P., Paradis V. Changing trends in malignant transformation of hepatocellular adenoma. Gut 2011, 60:85-89.
26. Bioulac-Sage P., Laumonier H., Couchy G., Le Bail B., Sa Cunha A., Rullier A., et al. Hepatocellular adenoma management and phenotypic classification: the Bordeaux experience. Hepatology 2009, 50:481-489.
27. Dokmak S., Paradis V., Vilgrain V., Sauvanet A., Farges O., Valla D., et al. A single-center surgical experience of 122 patients with single and multiple hepatocellular adenomas. Gastroenterology 2009, 137:1698-1705.
28. Terkivatan T., Ijzermans J.N. Hepatocellular adenoma: Should phenotypic classification direct management?. Nat Rev Gastroenterol Hepatol 2009, 6:697-698.
29. Van Aalten S.M., de Man R.A., Ijzermans J.N., Terkivatan T. Systematic review of haemorrhage and rupture of hepatocellular adenomas. Br J Surg 2012, 99:911-916.
30. Van Aalten S.M., Witjes C.D., de Man R.A., Ijzermans J.N., Terkivatan T. Can a decision-making model be justified in the management of hepatocellular adenoma?. Liver Int 2012, 32:28-37.
31. Sa Cunha A., Blanc J.F., Lazaro E., Mellottee L., Le Bail B., Zucman-Rossi J., et al. Inflammatory syndrome with liver adenomatosis: the beneficial effects of surgical management. Gut 2007, 56:307-309.
32. Noels J.E., van Aalten S.M., van der Windt D.J., et al. Management of hepatocellular adenoma during pregnancy. J Hepatol 2011, 54:553-558.
33. Bröker M.E., Ijzermans J.N., van Aalten S.M., de Man R.A., Terkivatan T. The management of pregnancy in women with hepatocellular adenoma: a plea for an individualized approach. Int J Hepatol 2012, 725735.