Augmenting transcranial direct current stimulation with D-cycloserine for depression: A pilot study

Journal of ECT

Volumn 29, Issue 3, 2013, Pages 196-200

  Chan, Herng Nieng ^a,b,c   Alonzo, Angelo ^a,b   Martin, Donel M ^a,b   Mitchell, Philip B ^a,b   Sachdev, Perminder ^a,d   Loo, Colleen K ^a,b,e  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

^b BLACK DOG INSTITUTE   (Australia)

^c SINGAPORE GENERAL HOSPITAL   (Singapore)

^d PRINCE OF WALES HOSPITAL   (Australia)

^e ST GEORGE HOSPITAL   (Australia)

Author keywords

Cycloserine; Depression; NMDA; tDCS

Indexed keywords

CYCLOSERINE; DESVENLAFAXINE; DULOXETINE; ESCITALOPRAM; FLUOXETINE; FLUVOXAMINE; HYPERICUM PERFORATUM EXTRACT; LITHIUM; MIRTAZAPINE; OLANZAPINE; PAROXETINE; PHENELZINE; QUETIAPINE; REBOXETINE; SERTRALINE; VENLAFAXINE;

ADULT; ANTIDEPRESSANT ACTIVITY; ARTICLE; BIPOLAR II DISORDER; CLINICAL ARTICLE; DEPRESSION; DIZZINESS; DRUG EFFICACY; DRUG TREATMENT FAILURE; ELECTROCONVULSIVE THERAPY; FEMALE; HUMAN; LETHARGY; MAINTENANCE THERAPY; MAJOR DEPRESSION; MALE; MONTGOMERY ASBERG DEPRESSION RATING SCALE; NERVE EXCITABILITY; OPEN STUDY; PILOT STUDY; PREFRONTAL CORTEX; PRURITUS; RATING SCALE; SKIN REDNESS; TRANSCRANIAL DIRECT CURRENT STIMULATION;

ADULT; ANTIMETABOLITES; BIPOLAR DISORDER; COMBINED MODALITY THERAPY; CYCLOSERINE; DEPRESSIVE DISORDER, MAJOR; DRUG RESISTANCE; ELECTRIC STIMULATION THERAPY; ELECTRODES; FEMALE; HUMANS; MALE; MIDDLE AGED; PILOT PROJECTS; PSYCHIATRIC STATUS RATING SCALES; RECEPTORS, N-METHYL-D-ASPARTATE;

EID: 84883553119     PISSN: 10950680     EISSN: 15334112     Source Type: Journal    
DOI: 10.1097/YCT.0b013e3182801b09     Document Type: Article

References (36)

1. Antal A, Nitsche MA, Paulus W. External modulation of visual perception in humans. Neuroreport. 2001;12:3553-3555
2. Baudewig J, Nitsche MA, Paulus W, et al. Regional modulation of BOLD MRI responses to human sensorimotor activation by transcranial direct current stimulation. Magn Reson Imaging. 2001;45:196-201
3. Fregni F, Boggio PS, Nitsche M, et al. Anodal transcranial direct current stimulation of prefrontal cortex enhances working memory. Exp Brain Res. 2005;166:23-30
4. Kincses ZT, Antal A, Nitsche MA, et al. Facilitation of probabilistic classification learning by transcranial direct current stimulation of the prefrontal cortex in the human. Neuropsychologia. 2003;42:113-117
5. Lang N, Siebner HR, Ward NS, et al. How does transcranial DC stimulation of the primary motor cortex alter regional neuronal activity in the human brain? Eur J Neurosci. 2005;22:495-504
6. Nitsche MA, Paulus W. Sustained excitability elevations induced by transcranial DC motor cortex stimulation in humans. Neurology. 2001;57:1899-1901
7. Boggio PS, Rigonatti SP, Ribeiro RB. A randomized double-blind clinical trial on the efficacy of cortical direct current stimulation for the treatment of major depression. Int J Neuropsychopharmacol. 2008;11:249-254
8. Fregni F, Boggio PS, Nitsche M, et al. Treatment of major depression with transcranial direct current stimulation. Bipolar Disord. 2006;8:203-205
9. Loo CK, Sachdev P, Martin D, et al. A double-blind, sham-controlled trial of transcranial direct current stimulation for the treatment of depression. Int J Neuropsychopharmacol. 2010;13:61-69
10. Loo C, Alonzo A, Martin D, et al. A three-week, randomized, sham-controlled trial of transcranial direct current stimulation in depression. Br J Psychiatry. 2012;200:1-8. DOI: 10.1192/ bjp.bp.111.097634
11. Kalu UG, Sexton CE, Loo CK, et al. Transcranial direct current stimulation in the treatment of major depression: A meta-analysis. [Published online ahead of print January 12]. Psychol Med. 2012;42:1791-1800
12. Nitsche MA, Jaussi W, Liebetanz D, et al. Consolidation of human motor cortical neuroplasticity by D-Cycloserine. Neuropsychopharmacology. 2004;29:1573-1578
13. Liebetanz D, Nitsche MA, Tergau F, et al. Pharmacological approach to the mechanisms of transcranial DC-stimulation-induced after-effects of human motor cortex excitability. Brain. 2002:125:2238-2247
14. Nitsche MA, Fricke K, Henschke U, et al. Pharmacological modulation of cortical excitability shifts induced by transcranial direct current stimulation in humans. J Physiol. 2003;553:293-301
15. Santini E, Muller RU, Quirk GJ. Consolidation of extinction learning involves transfer from NMDA-independent to NMDA-dependent memory. J Neurosci. 2001;21:9009-9017
16. Otto MW, Tolin DF, Simon NM, et al. Efficacy of D-cyloserine for enhancing response to cognitive-behavior therapy for panic disorder. Biol Psychiatry. 2010;67:365-370
17. Norberg MM, Kyrstal JH, Tolin DF. A meta-analysis of D-Cycloserine and the facilitation of fear extinction and exposure therapy. Biol Psychiatry. 2008;63:1118-1126
18. Bontempo A, Panza KE, Bloch MH. D-Cycloserine augmentation of behavioral therapy for the treatment of anxiety disorders: A meta-analysis. J Clin Psychiatry. 2012;73:533-537
19. Davis M, Ressler K, Rothbaum BO, et al. Effects of D-Cycloserine on extinction: Translation from preclinical to clinical work. Biol Psychiatry. 2006;60:369-375
20. VanBerckel BN, Lipsch C, Timp S, et al. Behavioral and neuroendocrine effects of the partial NMDA agonist D-Cycloserine in healthy subjects. Neuropsychopharmacology. 1997;16:317-324
21. Montgomery SA, Asberg M. A new depression scale designed to be sensitive to change. Br J Psychiatry. 1979;134:382-389
22. Berlim MT, Turecki G. Definition, assessment, and staging of treatment-resistant refractory major depression: A review of current concepts and methods. Can J Psychiatry. 2007;52:46-54
23. Blumberger DM, Tran LC, Fitzgerald PB, et al. A randomized double-blind sham-controlled study of transcranial direct current stimulation for treatment-resistant major depression. Front Psychiatry. 2012;3:74
24. Heresco-Levy U, Javitt DC, Gelfin Y, et al. Controlled trial of D-cycloserine adjuvant therapy for treatment-resistant major depressive disorder. J Affect Disord. 2006;93:239-243
25. Werner-Seidler A, Richardson R. Effects of D-cycloserine on extinction: Consequences of prior exposure to imipramine. Biol Psychiatry. 2004;62:1195-1197
26. Popik P, Wrobel M, Nowak G. Chronic treatment with antidepressants affects glycine/NMDA receptor function: Behavioral evidence. Neuropsychopharmacology. 2000;39:2278-2287
27. Poleszak E, Wla̧ P, Szewczyk B, et al. A complex interaction between glycine/NMDA receptors and serotonergic/noradrenergic antidepressants in the forced swim test in mice. J Neural Transm. 2011;118:1535-1546
28. Porsolt RD, Bertin A, Jalfre M. Behavioral despair in mice: A primary screening test for antidepressants. Arch Int Pharmacodyn Ther. 1977;229:327-336
29. Parnas AS, Weber M, Richardson R. Effects of multiple exposures to D-cycloserine on extinction of conditioned fear in rats. Neurobiol Learn Mem. 2005;83:224-231
30. Hood WF, Compton RP, Monahan JB. D-cycloserine: A ligand for the N-methyl-D-aspartate coupled glycine receptor has partial agonist characteristics. Neurosci Lett. 1989;98:91-95
31. Mickley GA, Remus JL, Ramos L, et al. Acute, but not chronic, exposure to D-cycloserine facilitates extinction and modulates spontaneous recovery of a conditioned taste aversion. Physiol Behav. 2012;105:417-427
32. Walker DL, Ressler KJ, Lu K, et al. Facilitation of conditioned fear extinction by systemic administration or intra-amygdala infusions of D-cycloserine as assessed with fear-potentiated startle in rats. J Neurosci. 2002;22:2343-2351
33. Ledgerwood L, Richarddson R, Cranney J. Effects of D-Cycloserine on extinction of conditioned freezing. Behav Neurosci. 2003;117:341-349
34. Hofmann SG, Meuret AE, Smits JAJ. Augmentation of exposure therapy with D-cycloserine for social anxiety disorder. Arch Gen Psychiatry. 2006;63:298-304
35. Ressler KJ, Rothbaum BO, Tannenbaum L. Cognitive enhancers as adjuncts to psychotherapy. Arch Gen Psychiatry. 2004;61:1136-1144
36. Lewis WC, Calden G, Thurston JR, et al. Psychiatric and neurological reactions to cycloserine in the treatment of tuberculosis. Dis Chest. 1957;32:172-182