Benzodiazepine use during buprenorphine treatment for opioid dependence: Clinical and safety outcomes

Drug and Alcohol Dependence

Volumn 132, Issue 3, 2013, Pages 580-586

  Schuman Olivier, Zev ^a,b   Hoeppner, Bettina B ^a,b   Weiss, Roger D ^a,d   Borodovsky, Jacob ^c,e   Shaffer, Howard J ^a,e   Albanese, Mark J ^a,e  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c TUFTS UNIVERSITY   (United States)

^d MCLEAN HOSPITAL   (United States)

^e CAMBRIDGE HEALTH ALLIANCE   (United States)

Author keywords

Accident; Benzodiazepine; Buprenorphine; Female; Opioid dependence; Utilization

Indexed keywords

BENZODIAZEPINE; BUPRENORPHINE; ILLICIT DRUG; OPIATE;

ACCIDENTAL INJURY; ADULT; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; DRUG MISUSE; DRUG OVERDOSE; DRUG SAFETY; EMERGENCY CARE; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; NEPHROTOXICITY; OPIATE ADDICTION; OUTPATIENT; PATIENT COMPLIANCE; PRESCRIPTION; PRIORITY JOURNAL; TREATMENT DURATION;

ACCIDENT; BENZODIAZEPINE; BUPRENORPHINE; FEMALE; OPIOID DEPENDENCE; UTILIZATION;

ACCIDENTS; ADULT; ANALGESICS, OPIOID; BENZODIAZEPINES; BUPRENORPHINE; EMERGENCY MEDICAL SERVICES; FEMALE; HUMANS; MALE; MIDDLE AGED; OPIATE SUBSTITUTION TREATMENT; OPIOID-RELATED DISORDERS; RETROSPECTIVE STUDIES; TREATMENT OUTCOME;

EID: 84883550939     PISSN: 03768716     EISSN: 18790046     Source Type: Journal    
DOI: 10.1016/j.drugalcdep.2013.04.006     Document Type: Article

References (43)

1. Alford D.P., LaBelle C.T., Kretsch N., Bergeron A., Winter M., Botticelli M., Samet J.H. Collaborative care of opioid-addicted patients in primary care using buprenorphine: five-year experience. Arch. Intern. Med. 2011, 171:425-431.
2. Anderson J.E. Prescribing of tranquillizers to women and men. CMAJ 1981, 125:1229-1232.
3. Barker M.J., Greenwood K.M., Jackson M., Crowe S.F. Cognitive effects of long-term benzodiazepine use: a meta-analysis. CNS Drugs 2004, 18:37-48.
4. Bell J.R., Butler B., Lawrance A., Batey R., Salmelainen P. Comparing overdose mortality associated with methadone and buprenorphine treatment. Drug Alcohol Depend. 2009, 104:73-77.
5. Bleich A., Gelkopf M., Weizman T., Adelson M. Benzodiazepine abuse in a methadone maintenance treatment clinic in Israel: characteristics and a pharmacotherapeutic approach. Isr. J. Psychiatry relat. Sci. 2002, 39:104-112.
6. Bramness J.G., Kornor H. Benzodiazepine prescription for patients in opioid maintenance treatment in Norway. Drug Alcohol Depend. 2007, 90:203-209.
7. Bramness J.G., Skurtveit S., Morland J. Clinical impairment of benzodiazepines-relation between benzodiazepine concentrations and impairment in apprehended drivers. Drug Alcohol Depend. 2002, 68:131-141.
8. Brands B., Blake J., Marsh D.C., Sproule B., Jeyapalan R., Li S. The impact of benzodiazepine use on methadone maintenance treatment outcomes. J. Addict. Dis. 2008, 27:37-48.
9. Brunette M.F., Noordsy D.L., Xie H., Drake R.E. Benzodiazepine use and abuse among patients with severe mental illness and co-occurring substance use disorders. Psychiatr. Serv. 2003, 54:1395-1401.
10. Chen K.W., Berger C.C., Forde D.P., D'Adamo C., Weintraub E., Gandhi D. Benzodiazepine use and misuse among patients in a methadone program. BMC Psychiatry 2011, 11:90.
11. Clausen T., Anchersen K., Waal H. Mortality prior to, during and after opioid maintenance treatment (OMT): a national prospective cross-registry study. Drug Alcohol Depend. 2008, 94:151-157.
12. Fiellin D.A., Moore B.A., Sullivan L.E., Becker W.C., Pantalon M.V., Chawarski M.C., Barry D.T., O'Connor P.G., Schottenfeld R.S. Long-term treatment with buprenorphine/naloxone in primary care: results at 2-5 years. Am. J. Addict. 2008, 17:116-120.
13. Gasser J.C., Kaufman R.D., Bellville J.W. Respiratory effects of lorazepam, pentobarbital, and pentazocine. Clin. Pharmacol. Ther. 1975, 18:170-174.
14. Gerra G., Leonardi C., D'Amore A., Strepparola G., Fagetti R., Assi C., Zaimovic A., Lucchini A. Buprenorphine treatment outcome in dually diagnosed heroin dependent patients: a retrospective study. Prog. Neuropsychopharmacol. Biol. Psychiatry 2006, 30:265-272.
15. Greenfield S.F., Weiss R.D., Griffin M.L. Patients who use drugs during inpatient substance abuse treatment. Am. J. Psychiatry 1992, 149:235-239.
16. Griffiths R.R., Johnson M.W. Relative abuse liability of hypnotic drugs: a conceptual framework and algorithm for differentiating among compounds. J. Clin. Psychiatry 2005, 66(Suppl. 9):31-41.
17. Gunderson E.W., Fiellin D.A. Office-based maintenance treatment of opioid dependence: how does it compare with traditional approaches?. CNS Drugs 2008, 22:99-111.
18. Hakkinen M., Launiainen T., Vuori E., Ojanpera I. Benzodiazepines and alcohol are associated with cases of fatal buprenorphine poisoning. Eur. J. Clin. Pharmacol. 2012, 68:301-309.
19. Lavie E., Fatseas M., Denis C., Auriacombe M. Benzodiazepine use among opiate-dependent subjects in buprenorphine maintenance treatment: correlates of use, abuse and dependence. Drug Alcohol Depend. 2009, 99:338-344.
20. Liebrenz M., Boesch L., Stohler R., Caflisch C. Agonist substitution-a treatment alternative for high-dose benzodiazepine-dependent patients?. Addiction 2010, 105:1870-1874.
21. Lintzeris N., Mitchell T.B., Bond A., Nestor L., Strang J. Interactions on mixing diazepam with methadone or buprenorphine in maintenance patients. J. Clin. Psychopharmacol. 2006, 26:274-283.
22. Lintzeris N., Nielsen S. Benzodiazepines, methadone and buprenorphine: interactions and clinical management. Am. J. Addict. 2010, 19:59-72.
23. Moody D.E., Fang W.B., Morrison J., McCance-Katz E. Gender differences in pharmacokinetics of maintenance dosed buprenorphine. Drug Alcohol Depend. 2011, 118:479-483.
24. Murray A., Bellville J.W., Comer W., Danielson L. Respiratory effects of quazepam and pentobarbital. J. Clin. Pharmacol. 1987, 27:310-313.
25. Nielsen S., Dietze P., Lee N., Dunlop A., Taylor D. Concurrent buprenorphine and benzodiazepines use and self-reported opioid toxicity in opioid substitution treatment. Addiction 2007, 102:616-622.
26. Nielsen S., Taylor D.A. The effect of buprenorphine and benzodiazepines on respiration in the rat. Drug Alcohol Depend. 2005, 79:95-101.
27. O'Brien C.P. Benzodiazepine use, abuse, and dependence. J. Clin. Psychiatry 2005, 66(Suppl. 2):28-33.
28. Oster G., Huse D.M., Adams S.F., Imbimbo J., Russell M.W. Benzodiazepine tranquilizers and the risk of accidental injury. Am. J. Public Health 1990, 80:1467-1470.
29. Oster G., Russell M.W., Huse D.M., Adams S.F., Imbimbo J. Accident- and injury-related health-care utilization among benzodiazepine users and nonusers. J. Clin. Psychiatry 1987, 48(Suppl. 17-21.).
30. Otto M.W., Bruce S.E., Deckersbach T. Benzodiazepine use, cognitive impairment, and cognitive-behavioral therapy for anxiety disorders: issues in the treatment of a patient in need. J. Clin. Psychiatry 2005, 66(Suppl. 2):34-38.
31. Otto M.W., McHugh R.K., Simon N.M., Farach F.J., Worthington J.J., Pollack M.H. Efficacy of CBT for benzodiazepine discontinuation in patients with panic disorder: further evaluation. Behav. Res. Ther. 2010, 48:720-727.
32. Ray W.A., Schaffner W., Federspiel C.F. Differences between female and male children in the receipt of prescribed psychotropic and controlled-analgesic drugs. A five-year epidemiologic study. Med. Care 1986, 24:801-813.
33. Reckitt-Benckiser Medication Suboxone Guide 2010, Slough, United Kingdom.
34. Reynaud M., Petit G., Potard D., Courty P. Six deaths linked to concomitant use of buprenorphine and benzodiazepines. Addiction 1998, 93:1385-1392.
35. Reynaud M., Tracqui A., Petit G., Potard D., Courty P. Six deaths linked to misuse of buprenorphine-benzodiazepine combinations. Am. J. Psychiatry 1998, 155:448-449.
36. Rosca P., Haklai Z., Goldberger N., Zohar P., Margolis A., Ponizovsky A.M. Mortality and causes of death among users of methadone maintenance treatment in Israel, 1999-2008. Drug Alcohol Depend. 2012, 125:160-163.
37. SAMHSA, 2011. HHS Publication No SMA 11-4618, Rockville, MD.
38. Schuman-Olivier Z., Albanese M., Nelson S.E., Roland L., Puopolo F., Klinker L., Shaffer H.J. Self-treatment: illicit buprenorphine use by opioid-dependent treatment seekers. J. Subst. Abuse Treat. 2010, 39:41-50.
39. Soyka M. To substitute or not substitute-optimal tactics for the management of benzodiazepine dependence. Addiction 2010, 105:1876-1877.
40. Swinson R.P. Clinical practice guidelines. Management of anxiety disorders. Can. J. Psychiatry 2006, 51:9S-91S.
41. Tyrer P. Benzodiazepine substitution for dependent patients-going with the flow. Addiction 2010, 105:1875-1876.
42. Yokell M.A., Zaller N.D., Green T.C., Rich J.D. Buprenorphine and buprenorphine/naloxone diversion, misuse, and illicit use: an international review. Curr. Drug Abuse Rev. 2011, 4:28-41.
43. Yonkers K.A., Kando J.C., Cole J.O., Blumenthal S. Gender differences in pharmacokinetics and pharmacodynamics of psychotropic medication. Am. J. Psychiatry 1992, 149:587-595.