Structural basis for recognition of the third SH3 domain of full-length R85 (R85FL)/ponsin by ataxin-7

FEBS Letters

Volumn 587, Issue 18, 2013, Pages 2905-2911

  Jiang, Ya Jun ^a   Zhou, Chen Jie ^a   Zhou, Zi Ren ^a   Wu, Meng ^a   Hu, Hong Yu ^a  

^a INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

Author keywords

Ataxin 7; Inclusion body; Polyglutamine; Proline rich region; R85FL ponsin; SH3 domain

Indexed keywords

4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; ADAPTOR PROTEIN; ATAXIN 7; PEPTIDE; POLYGLUTAMINE; PONSIN; PROLINE RICH PROTEIN; PROTEIN PP2; PROTEIN SH3; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; GENE; GENETIC VARIABILITY; MICROSCOPY; MOLECULAR RECOGNITION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PATHOGENESIS; PONSIN GENE; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN DOMAIN; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; SPINOCEREBELLAR DEGENERATION; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; SURFACE PROPERTY;

ATAXIN-7; ATX7; FULL-LENGTH R85; INCLUSION BODY; POLYGLUTAMINE; POLYQ; PROLINE-RICH REGION; PRR; R85FL; R85FL/PONSIN; SCA7; SH3; SH3 DOMAIN; SPINOCEREBELLAR ATAXIA 7; SRC HOMOLOGY 3;

ALTERNATIVE SPLICING; BINDING SITES; CELL NUCLEUS; ESCHERICHIA COLI; GENE EXPRESSION; HEK293 CELLS; HUMANS; INCLUSION BODIES; MICROFILAMENT PROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; PEPTIDES; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; RECOMBINANT FUSION PROTEINS; SEQUENCE ALIGNMENT; STATIC ELECTRICITY;

EID: 84883490794     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2013.07.021     Document Type: Article

References (37)

1. A.S. Lebre, and A. Brice Spinocerebellar ataxia 7 (SCA7) Cytogenet. Genome Res. 100 2003 154 163
2. G.A. Garden, and A.R. La Spada Molecular pathogenesis and cellular pathology of spinocerebellar ataxia type 7 neurodegeneration Cerebellum 7 2008 138 149
3. G. David Cloning of the SCA7 gene reveals a highly unstable CAG repeat expansion Nat. Genet. 17 1997 65 70
4. V.B. Palhan Polyglutamine-expanded ataxin-7 inhibits STAGA histone acetyltransferase activity to produce retinal degeneration Proc. Natl. Acad. Sci. USA 102 2005 8472 8477
5. S.J. McMahon, M.G. Pray-Grant, D. Schieltz, J.R. Yates 3rd, and P.A. Grant Polyglutamine-expanded spinocerebellar ataxia-7 protein disrupts normal SAGA and SLIK histone acetyltransferase activity Proc. Natl. Acad. Sci. USA 102 2005 8478 8482
6. A. Kohler, M. Schneider, G.G. Cabal, U. Nehrbass, and E. Hurt Yeast ataxin-7 links histone deubiquitination with gene gating and mRNA export Nat. Cell Biol. 10 2008 707 715
7. L.S. Havel, S. Li, and X.J. Li Nuclear accumulation of polyglutamine disease proteins and neuropathology Mol. Brain 2 2009 21
8. N. Kioka, K. Ueda, and T. Amachi Vinexin, CAP/ponsin, ArgBP2: a novel adaptor protein family regulating cytoskeletal organization and signal transduction Cell Struct. Funct. 27 2002 1 7
9. S.S. Li Specificity and versatility of SH3 and other proline-recognition domains: structural basis and implications for cellular signal transduction Biochem. J. 390 2005 641 653
10. A. Zarrinpar, R.P. Bhattacharyya, and W.A. Lim The structure and function of proline recognition domains Sci. STKE 2003 RE8
11. Y.G. Gao, X.Z. Yan, A.X. Song, Y.G. Chang, X.C. Gao, N. Jiang, Q. Zhang, and H.Y. Hu Structural insights into the specific binding of huntingtin proline-rich region with the SH3 and WW domains Structure 14 2006 1755 1765
12. G. Cesareni Modular Protein Domains 2005 Wiley-VCH Weinheim
13. A.S. Lebre Ataxin-7 interacts with a Cbl-associated protein that it recruits into neuronal intranuclear inclusions Hum. Mol. Genet. 10 2001 1201 1213
14. W.J. Bao, Y.G. Gao, Y.G. Chang, T.Y. Zhang, X.J. Lin, X.Z. Yan, and H.Y. Hu Highly efficient expression and purification system of small-size protein domains in Escherichia coli for biochemical characterization Protein Expr. Purif. 47 2006 599 606
15. L.J. Berliner, J. Grunwald, H.O. Hankovszky, and K. Hideg A novel reversible thiol-specific spin label: papain active site labeling and inhibition Anal. Biochem. 119 1982 450 455
16. S.J. de Vries, A.D. van Dijk, M. Krzeminski, M. van Dijk, A. Thureau, V. Hsu, T. Wassenaar, and A.M. Bonvin HADDOCK versus HADDOCK: new features and performance of HADDOCK2.0 on the CAPRI targets Proteins 69 2007 726 733
17. J. Kim, C.D. Lee, A. Rath, and A.R. Davidson Recognition of non-canonical peptides by the yeast Fus1p SH3 domain: elucidation of a common mechanism for diverse SH3 domain specificities J. Mol. Biol. 377 2008 889 901
18. K. Gehmlich Paxillin and ponsin interact in nascent costameres of muscle cells J. Mol. Biol. 369 2007 665 682
19. J. Zhang, X. Li, B. Yao, W. Shen, H. Sun, C. Xu, J. Wu, and Y. Shi Solution structure of the first SH3 domain of human vinexin and its interaction with vinculin peptides Biochem. Biophys. Res. Commun. 357 2007 931 937
20. M.C. Good, J.G. Zalatan, and W.A. Lim Scaffold proteins: hubs for controlling the flow of cellular information Science 332 2011 680 686
21. L. Buday, and P. Tompa Functional classification of scaffold proteins and related molecules FEBS J. 277 2010 4348 4355
22. V. Ribon, J.A. Printen, N.G. Hoffman, B.K. Kay, and A.R. Saltiel A novel, multifuntional c-Cbl binding protein in insulin receptor signaling in 3T3-L1 adipocytes Mol. Cell. Biol. 18 1998 872 879
23. K. Mandai, H. Nakanishi, A. Satoh, K. Takahashi, K. Satoh, H. Nishioka, A. Mizoguchi, and Y. Takai Ponsin/SH3P12: an l-afadin- and vinculin-binding protein localized at cell-cell and cell-matrix adherens junctions J. Cell Biol. 144 1999 1001 1017
24. W.H. Lin, C.J. Huang, M.W. Liu, H.M. Chang, Y.J. Chen, T.Y. Tai, and L.M. Chuang Cloning, mapping, and characterization of the human sorbin and SH3 domain containing 1 (SORBS1) gene: a protein associated with c-Abl during insulin signaling in the hepatoma cell line Hep3B Genomics 74 2001 12 20
25. A. Kurakin, N.G. Hoffman, and B.K. Kay Molecular recognition properties of the C-terminal Sh3 domain of the Cbl associated protein, Cap J. Pept. Res. 52 1998 331 337
26. F. Bauer, K. Schweimer, H. Meiselbach, S. Hoffmann, P. Rosch, and H. Sticht Structural characterization of Lyn-SH3 domain in complex with a herpesviral protein reveals an extended recognition motif that enhances binding affinity Protein Sci. 14 2005 2487 2498
27. M. Lewitzky, M. Harkiolaki, M.C. Domart, E.Y. Jones, and S.M. Feller Mona/Gads SH3C binding to hematopoietic progenitor kinase 1 (HPK1) combines an atypical SH3 binding motif, R/KXXK, with a classical PXXP motif embedded in a polyproline type II (PPII) helix J. Biol. Chem. 279 2004 28724 28732
28. A. Hoelz, J.M. Janz, S.D. Lawrie, B. Corwin, A. Lee, and T.P. Sakmar Crystal structure of the SH3 domain of betaPIX in complex with a high affinity peptide from PAK2 J. Mol. Biol. 358 2006 509 522
29. E.J. Stollar, B. Garcia, P.A. Chong, A. Rath, H. Lin, J.D. Forman-Kay, and A.R. Davidson Structural, functional, and bioinformatic studies demonstrate the crucial role of an extended peptide binding site for the SH3 domain of yeast Abp1p J. Biol. Chem. 284 2009 26918 26927
30. M. Harkiolaki Distinct binding modes of two epitopes in Gab2 that interact with the SH3C domain of Grb2 Structure 17 2009 809 822
31. H.T. Orr, and H.Y. Zoghbi Trinucleotide repeat disorders Annu. Rev. Neurosci. 30 2007 575 621
32. Y.J. Jiang, M.X. Che, J.Q. Yuan, Y.Y. Xie, X.Z. Yan, and H.Y. Hu Interaction with polyglutamine-expanded huntingtin alters cellular distribution and RNA processing of huntingtin yeast two-hybrid protein A (HYPA) J. Biol. Chem. 286 2011 25236 25245
33. V. Ribon, R. Herrera, B.K. Kay, and A.R. Saltiel A role for CAP, a novel, multifunctional Src homology 3 domain-containing protein in formation of actin stress fibers and focal adhesions J. Biol. Chem. 273 1998 4073 4080
34. M.F. Langhorst, F.A. Jaeger, S. Mueller, L. Sven Hartmann, G. Luxenhofer, and C.A. Stuermer Reggies/flotillins regulate cytoskeletal remodeling during neuronal differentiation via CAP/ponsin and Rho GTPases Eur. J. Cell Biol. 87 2008 921 931
35. C.A. Baumann CAP defines a second signalling pathway required for insulin-stimulated glucose transport Nature 407 2000 202 207
36. L.A. Lesniewski Bone marrow-specific Cap gene deletion protects against high-fat diet-induced insulin resistance Nat. Med. 13 2007 455 462
37. D. Tosoni, and G. Cestra CAP (Cbl associated protein) regulates receptor-mediated endocytosis FEBS Lett. 583 2009 293 300