메뉴 건너뛰기




Volumn 72, Issue 3, 2013, Pages 529-535

Clinical effects of A4889G and T6235C polymorphisms in cytochrome P-450 CYP1A1 for breast cancer patients treated with tamoxifen: Implications for tumor aggressiveness and patient survival

Author keywords

Breast neoplasm; Cytochrome P 450 CYP1A1; Polymorphism; Survival; Tamoxifen

Indexed keywords

ALANINE; CYSTEINE; CYTOCHROME P450 1A1; GLYCINE; TAMOXIFEN; THREONINE;

EID: 84883490786     PISSN: 03445704     EISSN: 14320843     Source Type: Journal    
DOI: 10.1007/s00280-013-2221-y     Document Type: Article
Times cited : (4)

References (26)
  • 1
    • 0346602691 scopus 로고    scopus 로고
    • Active tamoxifen metabolite plasma concentrations after coadministration of tamoxifen and the selective serotonin reuptake inhibitor paroxetine
    • 10.1093/jnci/djg108 1:CAS:528:DC%2BD3sXpvVelsbc%3D
    • Stearns V, Johnson MD, Rae JM et al (2003) Active tamoxifen metabolite plasma concentrations after coadministration of tamoxifen and the selective serotonin reuptake inhibitor paroxetine. J Natl Cancer Inst 95:1758-1764
    • (2003) J Natl Cancer Inst , vol.95 , pp. 1758-1764
    • Stearns, V.1    Johnson, M.D.2    Rae, J.M.3
  • 2
    • 3342932419 scopus 로고    scopus 로고
    • Pharmacological characterization of 4-hydroxy-N-desmethyl tamoxifen, a novel active metabolite of tamoxifen
    • 10.1023/B:BREA.0000025406.31193.e8 1:CAS:528:DC%2BD2cXjsVertbc%3D
    • Johnson MD, Zuo H, Lee KH et al (2004) Pharmacological characterization of 4-hydroxy-N-desmethyl tamoxifen, a novel active metabolite of tamoxifen. Breast Cancer Res Treat 85:151-159
    • (2004) Breast Cancer Res Treat , vol.85 , pp. 151-159
    • Johnson, M.D.1    Zuo, H.2    Lee, K.H.3
  • 3
    • 17644387537 scopus 로고    scopus 로고
    • Endoxifen (4-hydroxy-N-desmethyl-tamoxifen) has anti-estrogenic effects in breast cancer cells with potency similar to 4-hydroxy-tamoxifen
    • 10.1007/s00280-004-0926-7 1:CAS:528:DC%2BD2MXjtVWmtrk%3D
    • Lim YC, Desta Z, Flockhart DA, Skaar TC (2005) Endoxifen (4-hydroxy-N-desmethyl-tamoxifen) has anti-estrogenic effects in breast cancer cells with potency similar to 4-hydroxy-tamoxifen. Cancer Chemother Pharmacol 55:471-478
    • (2005) Cancer Chemother Pharmacol , vol.55 , pp. 471-478
    • Lim, Y.C.1    Desta, Z.2    Flockhart, D.A.3    Skaar, T.C.4
  • 4
    • 0034012358 scopus 로고    scopus 로고
    • Concentrations of tamoxifen and its major metabolites in hormone responsive and resistant breast tumours
    • 10.1054/bjoc.2000.1120 1:CAS:528:DC%2BD3cXjvVChu7k%3D
    • MacCallum J, Cummings J, Dixon JM, Miller WR (2000) Concentrations of tamoxifen and its major metabolites in hormone responsive and resistant breast tumours. Br J Cancer 82:1629-1635
    • (2000) Br J Cancer , vol.82 , pp. 1629-1635
    • Maccallum, J.1    Cummings, J.2    Dixon, J.M.3    Miller, W.R.4
  • 5
    • 11144355178 scopus 로고    scopus 로고
    • Tamoxifen and metabolite concentrations in serum and breast cancer tissue during three dose regimens in a randomized preoperative trial
    • 10.1158/1078-0432.CCR-03-0538 1:CAS:528:DC%2BD2cXivFSqs78%3D
    • Kisanga ER, Gjerde J, Guerrieri-Gonzaga A et al (2004) Tamoxifen and metabolite concentrations in serum and breast cancer tissue during three dose regimens in a randomized preoperative trial. Clin Cancer Res 10:2336-2343
    • (2004) Clin Cancer Res , vol.10 , pp. 2336-2343
    • Kisanga, E.R.1    Gjerde, J.2    Guerrieri-Gonzaga, A.3
  • 6
    • 0345724797 scopus 로고    scopus 로고
    • Biotransformation of tamoxifen in a human endometrial explant culture model
    • 10.1016/j.cbi.2003.06.002 1:CAS:528:DC%2BD3sXpt1Wit78%3D
    • Sharma M, Shubert DE, Sharma M et al (2003) Biotransformation of tamoxifen in a human endometrial explant culture model. Chem Biol Interact 146:237-249
    • (2003) Chem Biol Interact , vol.146 , pp. 237-249
    • Sharma, M.1    Shubert, D.E.2    Sharma, M.3
  • 7
    • 24944435434 scopus 로고    scopus 로고
    • Oxidation of tamoxifen by human flavin-containing monooxygenase (FMO) 1 and FMO3 to tamoxifen-N-oxide and its novel reduction back to tamoxifen by human cytochromes P450 and hemoglobin
    • 10.1124/dmd.104.000802 1:CAS:528:DC%2BD2MXhtVKrurnL
    • Parte P, Kupfer D (2005) Oxidation of tamoxifen by human flavin-containing monooxygenase (FMO) 1 and FMO3 to tamoxifen-N-oxide and its novel reduction back to tamoxifen by human cytochromes P450 and hemoglobin. Drug Metab Dispos 33:1446-1452
    • (2005) Drug Metab Dispos , vol.33 , pp. 1446-1452
    • Parte, P.1    Kupfer, D.2
  • 8
    • 46149095280 scopus 로고    scopus 로고
    • CYP450 pharmacogenetics for personalizing cancer therapy
    • 10.1016/j.drup.2008.03.002
    • van Schaik RH (2008) CYP450 pharmacogenetics for personalizing cancer therapy. Drug Resist Updat 11:77-98
    • (2008) Drug Resist Updat , vol.11 , pp. 77-98
    • Van Schaik, R.H.1
  • 9
    • 4243063941 scopus 로고    scopus 로고
    • Comprehensive evaluation of tamoxifen sequential biotransformation by the human cytochrome P450 system in vitro: Prominent roles for CYP3A and CYP2D6
    • 10.1124/jpet.104.065607 1:CAS:528:DC%2BD2cXnt1eqtb0%3D
    • Desta Z, Ward BA, Soukhova NV, Flockhart DA (2004) Comprehensive evaluation of tamoxifen sequential biotransformation by the human cytochrome P450 system in vitro: prominent roles for CYP3A and CYP2D6. J Pharmacol Exp Ther 310:1062-1075
    • (2004) J Pharmacol Exp Ther , vol.310 , pp. 1062-1075
    • Desta, Z.1    Ward, B.A.2    Soukhova, N.V.3    Flockhart, D.A.4
  • 10
    • 34748901348 scopus 로고    scopus 로고
    • Glucuronidation of active tamoxifen metabolites by the human UDP glucuronosyltransferases
    • 10.1124/dmd.107.017145 1:CAS:528:DC%2BD2sXht1Cnu7vJ
    • Sun D, Sharma AK, Dellinger RW et al (2007) Glucuronidation of active tamoxifen metabolites by the human UDP glucuronosyltransferases. Drug Metab Dispos 35:2006-2014
    • (2007) Drug Metab Dispos , vol.35 , pp. 2006-2014
    • Sun, D.1    Sharma, A.K.2    Dellinger, R.W.3
  • 11
    • 0037094334 scopus 로고    scopus 로고
    • Reverse geometrical selectivity in glucuronidation and sulfation of cis- and trans-4-hydroxytamoxifens by human liver UDP-glucuronosyltransferases and sulfotransferases
    • 10.1016/S0006-2952(02)00994-2 1:CAS:528:DC%2BD38XktVCit7c%3D
    • Nishiyama T, Ogura K, Nakano H et al (2002) Reverse geometrical selectivity in glucuronidation and sulfation of cis- and trans-4- hydroxytamoxifens by human liver UDP-glucuronosyltransferases and sulfotransferases. Biochem Pharmacol 63:1817-1830
    • (2002) Biochem Pharmacol , vol.63 , pp. 1817-1830
    • Nishiyama, T.1    Ogura, K.2    Nakano, H.3
  • 12
    • 33645122881 scopus 로고    scopus 로고
    • Pharmacogenetics of human cytosolic sulfotransferases
    • 10.1038/sj.onc.1209376 1:CAS:528:DC%2BD28XisFyhtbk%3D
    • Nowell S, Falany CN (2006) Pharmacogenetics of human cytosolic sulfotransferases. Oncogene 25:1673-1678
    • (2006) Oncogene , vol.25 , pp. 1673-1678
    • Nowell, S.1    Falany, C.N.2
  • 13
    • 77955556907 scopus 로고    scopus 로고
    • Cytochrome P450 2D6 and outcomes of adjuvante tamoxifen therapy: Results of a meta-analysis
    • 10.1007/s10549-010-0902-3 1:CAS:528:DC%2BC3cXoslehsbc%3D
    • Seruga B, Amir E (2010) Cytochrome P450 2D6 and outcomes of adjuvante tamoxifen therapy: results of a meta-analysis. Breast Cancer Res Treat 122(3):609-617
    • (2010) Breast Cancer Res Treat , vol.122 , Issue.3 , pp. 609-617
    • Seruga, B.1    Amir, E.2
  • 14
    • 78650890739 scopus 로고    scopus 로고
    • CYP2D6 gene variants: Association with breast cancer specific survival in a cohort of breast cancer patients from the United Kingdom treated with adjuvant tamoxifen
    • 10.1186/bcr2629
    • Abrahan JE, Maranian MJ, Driver KE et al (2010) CYP2D6 gene variants: association with breast cancer specific survival in a cohort of breast cancer patients from the United Kingdom treated with adjuvant tamoxifen. Breast Cancer Res 12(4):R64
    • (2010) Breast Cancer Res , vol.12 , Issue.4 , pp. 64
    • Abrahan, J.E.1    Maranian, M.J.2    Driver, K.E.3
  • 15
    • 61649086428 scopus 로고    scopus 로고
    • Estrogen metabolism and breast cancer: A risk model
    • 10.1111/j.1749-6632.2008.03676.x 1:CAS:528:DC%2BD1MXktFKlsbo%3D
    • Parl FF, Dawling S, Roodi N, Crooke PS (2009) Estrogen metabolism and breast cancer: a risk model. Ann NY Acad Sci 1155:68-75
    • (2009) Ann NY Acad Sci , vol.1155 , pp. 68-75
    • Parl, F.F.1    Dawling, S.2    Roodi, N.3    Crooke, P.S.4
  • 16
    • 23844494772 scopus 로고    scopus 로고
    • Cytochrome P450-mediated metabolism of estrogens and its regulation in human
    • 10.1016/j.canlet.2004.10.007 1:CAS:528:DC%2BD2MXosVaju7s%3D
    • Tsuchiya Y, Nakajima M, Yokoi T (2005) Cytochrome P450-mediated metabolism of estrogens and its regulation in human. Cancer Lett 227:115-124
    • (2005) Cancer Lett , vol.227 , pp. 115-124
    • Tsuchiya, Y.1    Nakajima, M.2    Yokoi, T.3
  • 17
    • 79953809066 scopus 로고    scopus 로고
    • Polymorphisms in the 5′- and 3′-untranslated region of the VEGF gene and sporadic breast cancer risk and clinicopathologic characteristics
    • 10.1007/s13277-010-0121-x 1:CAS:528:DC%2BC3MXitleitrs%3D
    • Oliveira C, Lourenço GJ, Silva PM et al (2011) Polymorphisms in the 5′- and 3′-untranslated region of the VEGF gene and sporadic breast cancer risk and clinicopathologic characteristics. Tumour Biol 32:295-300
    • (2011) Tumour Biol , vol.32 , pp. 295-300
    • Oliveira, C.1    Lourenço, G.J.2    Silva, P.M.3
  • 18
    • 84873579639 scopus 로고    scopus 로고
    • Clinical and pathological implications of GSTM1 and GSTT1 gene deletions in sporadic breast cancer
    • 10.1007/s12156-008-0054-4
    • Cardoso-Filho C, Lourenço GJ, Shinzato JY, Zeferino LC, Costa FF (2008) Clinical and pathological implications of GSTM1 and GSTT1 gene deletions in sporadic breast cancer. Oncol Rev 2:36-43
    • (2008) Oncol Rev , vol.2 , pp. 36-43
    • Cardoso-Filho, C.1    Lourenço, G.J.2    Shinzato, J.Y.3    Zeferino, L.C.4    Costa, F.F.5
  • 20
    • 1542513942 scopus 로고    scopus 로고
    • Genetic polymorphisms and susceptibility to childhood acute lymphoblastic leukemia
    • 10.1002/em.20003 1:CAS:528:DC%2BD2cXisFGlsb4%3D
    • Canalle R, Burim RV, Tone LG, Takahashi CS (2004) Genetic polymorphisms and susceptibility to childhood acute lymphoblastic leukemia. Environ Mol Mutagen 43:100-109
    • (2004) Environ Mol Mutagen , vol.43 , pp. 100-109
    • Canalle, R.1    Burim, R.V.2    Tone, L.G.3    Takahashi, C.S.4
  • 21
    • 0037743885 scopus 로고    scopus 로고
    • Association of GSTM1, CYP1A1 and CYP2E1 genetic polymorphisms with susceptibility to lung adenocarcinoma: A case-control study in Chinese population
    • 10.1111/j.1349-7006.2003.tb01463.x 1:CAS:528:DC%2BD3sXls1WrtLg%3D
    • Wang J, Deng Y, Li L et al (2003) Association of GSTM1, CYP1A1 and CYP2E1 genetic polymorphisms with susceptibility to lung adenocarcinoma: a case-control study in Chinese population. Cancer Sci 94:448-452
    • (2003) Cancer Sci , vol.94 , pp. 448-452
    • Wang, J.1    Deng, Y.2    Li, L.3
  • 22
    • 4744363964 scopus 로고    scopus 로고
    • Genetic polymorphisms of CYP1A1, CYP2D6, GSTM1, GSTT1 and susceptibility to acute lymphoblastic leukaemia in Indian children
    • 10.1002/pbc.20074
    • Joseph T, Kusumakumary P, Chacko P, Abraham A, Radhakrishna Pillai M (2004) Genetic polymorphisms of CYP1A1, CYP2D6, GSTM1, GSTT1 and susceptibility to acute lymphoblastic leukaemia in Indian children. Pediatr Blood Cancer 43:560-567
    • (2004) Pediatr Blood Cancer , vol.43 , pp. 560-567
    • Joseph, T.1    Kusumakumary, P.2    Chacko, P.3    Abraham, A.4    Radhakrishna Pillai, M.5
  • 23
    • 0021352552 scopus 로고
    • Antiestrogen action of 2-hydroxyestrone on MCF-7 human breast cancer cells
    • 1:CAS:528:DyaL2cXhvVKisLs%3D
    • Schneider J, Huh MM, Bradlow LH, Fishman J (1984) Antiestrogen action of 2-hydroxyestrone on MCF-7 human breast cancer cells. J Biol Chem 259:4840-4845
    • (1984) J Biol Chem , vol.259 , pp. 4840-4845
    • Schneider, J.1    Huh, M.M.2    Bradlow, L.H.3    Fishman, J.4
  • 24
    • 0028220858 scopus 로고
    • Endogenous estrogen metabolite 2-methoxyestradiol inhibits angiogenesis and suppresses tumor growth
    • 10.1038/368237a0 1:CAS:528:DyaK2cXitlKns7Y%3D
    • Fotsis T, Zhang Y, Pepper MS et al (1994) Endogenous estrogen metabolite 2-methoxyestradiol inhibits angiogenesis and suppresses tumor growth. Nature 368:237-239
    • (1994) Nature , vol.368 , pp. 237-239
    • Fotsis, T.1    Zhang, Y.2    Pepper, M.S.3
  • 25
    • 0029008622 scopus 로고
    • Synthesis, antitubulin and antimitotic activity, and cytotoxicity of analogs of 2-methoxyestradiol, an endogenous mammalian metabolite of estradiol that inhibits tubulin polymerization by binding to the colchicine binding site
    • 10.1021/jm00012a003 1:CAS:528:DyaK2MXlvFahtbg%3D
    • Cushman M, He HM, Katzenellenbogan JA, Lin CM, Hamel E (1995) Synthesis, antitubulin and antimitotic activity, and cytotoxicity of analogs of 2-methoxyestradiol, an endogenous mammalian metabolite of estradiol that inhibits tubulin polymerization by binding to the colchicine binding site. J Med Chem 38:2041-2049
    • (1995) J Med Chem , vol.38 , pp. 2041-2049
    • Cushman, M.1    He, H.M.2    Katzenellenbogan, J.A.3    Lin, C.M.4    Hamel, E.5
  • 26
    • 77955837344 scopus 로고    scopus 로고
    • Breast cancer precursors revisited: Molecular features and progression pathways
    • 10.1111/j.1365-2559.2010.03568.x
    • Lopez-Garcia MA, Geyer FC, Lacroix-Triki M, Marchió C, Reis-Filho JS (2010) Breast cancer precursors revisited: molecular features and progression pathways. Histopathology 57(2):171-192
    • (2010) Histopathology , vol.57 , Issue.2 , pp. 171-192
    • Lopez-Garcia, M.A.1    Geyer, F.C.2    Lacroix-Triki, M.3    Marchió, C.4    Reis-Filho, J.S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.