Radiosensitivity enhancement of human hepatocellular carcinoma cell line SMMC-7721 by sorafenib through the MEK/ERK signal pathway

International Journal of Radiation Biology

Volumn 89, Issue 9, 2013, Pages 724-731

  Dai, Xiao Fang ^a   Ding, Jie ^a   Zhang, Rui Guang ^a   Ren, Jing Hua ^a   Ma, C M Charlie ^b   Wu, Gang ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b FOX CHASE CANCER CENTER   (United States)

Author keywords

Hepatocellular carcinoma; MEK ERK; Radiosensitization; Sorafenib

Indexed keywords

DOUBLE STRANDED DNA; HISTONE H2AX; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; PROTEIN KINASE B; SORAFENIB;

ARTICLE; CELL VIABILITY; CLONOGENIC ASSAY; CONTROLLED STUDY; DNA DAMAGE; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IMMUNOFLUORESCENCE TEST; LIVER CELL CARCINOMA; PRIORITY JOURNAL; RADIOSENSITIVITY; RADIOSENSITIZATION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CELL SURVIVAL; DNA REPAIR; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; LIVER NEOPLASMS; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; NIACINAMIDE; PHENYLUREA COMPOUNDS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RADIATION-SENSITIZING AGENTS;

EID: 84883479608     PISSN: 09553002     EISSN: 13623095     Source Type: Journal    
DOI: 10.3109/09553002.2013.791405     Document Type: Article

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