Fluorescent AIE dots encapsulated organically modified silica (ORMOSIL) nanoparticles for two-photon cellular imaging

Science China Chemistry

Volumn 56, Issue 9, 2013, Pages 1247-1252

  Zhu, Zhenfeng ^a   Zhao, Xinyuan ^b   Qin, Wei ^c   Chen, Guangdi ^b   Qian, Jun ^a   Xu, Zhengping ^b  

^a ZHEJIANG UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Hong Kong)

Author keywords

aggregation induced emission; nucleus permeability; organically modified silica; TTF; two photon

Indexed keywords

AGGREGATION-INDUCED EMISSIONS; FLUORESCENCE IMAGING; FLUORESCENCE INTENSITIES; ORGANICALLY MODIFIED SILICA; ORMOSIL NANOPARTICLES; TTF; TWO PHOTON; TWO-PHOTON FLUORESCENCE MICROSCOPY;

BIOCOMPATIBILITY; CYTOLOGY; FLUORESCENCE; PHOTONS; SILICA;

NANOPARTICLES;

EID: 84883464514     PISSN: 16747291     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11426-013-4943-4     Document Type: Article

References (21)

1. Wang Y, Shyy JYJ, Chien S. Fluorescence proteins, live-cell imaging, and mechanobiology: Seeing is believing. Ann Rev Biomed Eng, 2008, 10:1-38
2. Van Engelenburg SB, Palmer AE. Fluorescent biosensors of protein function. Curr Opin Chem Biol, 2008, 12:60-65
3. Borisov SM, Wolfbeis OS. Optical biosensors. Chem Rev, 2008, 108:423-461
4. Domaille DW, Que EL, Chang CJ. Synthetic fluorescent sensors for studying the cell biology of metals. Nat Chem Biol, 2008, 4:168-175
5. Birks JB. Photophysics of Aromatic Molecules. New York: Wiley-Interscience, 1970
6. Qin W, Ding D, Liu JZ, Yuan WZ, Hu Y, Liu B, Tang BZ. Biocompatible nanoparticles with aggregation-induced emission characteristics as far-red/near-infrared fluorescent bioprobes for in vitro and in vivo imaging applications. Adv Funct Mater 2012, 4:771-779
7. Luo J, Xie Z, Lam JWY, Cheng L, Chen H, Qiu C, Kwok HS, Zhan X, Liu Y, Zhu D, Tang BZ. Aggregation-induced emission of 1-methyl-1,2,3,4,5- pentaphenylsilole. Chem Commun, 2001, 1740-1741
8. Tang BZ, Zhan X, Yu G, Lee PPS, Liu Y, Zhu D. Efficient blue emission from siloles. J Mater Chem, 2001, 11:2974-2978
9. Li K, Qin W, Ding D, Tomczak N, Geng JL, Liu RR, Liu JZ, Zhang XH, Liu HW, Liu B and Tang BZ. Photostable fluorescent organic dots with aggregation-induced emission (AIE dots) for noninvasive long-term cell tracing. Sci Rep 2013, 3:1150
10. Zhao QL, Li K, Chen SJ, Qin AJ, Ding D, Zhang S, Liu Y, Liu B, Sun JZ, Tang BZ. Aggregation-induced red-NIR emission organic nanoparticles as effective and photostable fluorescent probes for bioimaging. J Mater Chem, 2012, 22:15128-15135
11. Yu Y, Feng C, Hong Y, Liu JZ, Chen SJ, Ng KM, Luo QK, Tang BZ. Cytophilic fluorescent bioprobes for long-term cell tracking. Adv Mater, 2011, 23:3298-3302
12. Hong YN, Lam JWY, and Tang BZ. Aggregation-induced emission: phenomenon, mechanism and applications, Chem Commun, 2009, (29): 4332-4353
13. Geng JL, Li K, Ding D, Zhang XH, Qin W, Liu JZ, Tang BZ, Liu B. Lipid-PEG-Folate encapsulated nanoparticles with aggregation induced emission characteristics: Cellular uptake mechanism and two-photon fluorescence imaging. Small, 2012, 23:3655-3663
14. Chan CPY, Haeussler M, Tang BZ, Dong Y, Sin KK. Mak WC, Trau D, Seydack M, Renneberg R. Silole nanocrystals as novel biolabels. Immunol J Methods, 2004, 295:111-118
15. Hong Y, Haeussler M, Lam MJY, Li Z, Sin KK, Dong Y, Tong H, Liu J, Qin A, Renneberg R, Tang BZ. Label-free fluorescent probing of G-quadruplex formation and real-time monitoring of DNA folding by a quaternized tetraphenylethene salt with aggregation-induced emission characteristics. Chem Eur J, 2008, 14:6428-6437
16. Yu Y, Hong YN, Feng C, Liu JZ, Lam JWY, Faisal M, Ng KM, Luo KQ and Tang BZ. Synthesis of an AIE-active fluorogen and its application in cell imaging. Sci China Ser B-Chem, 2009, 52:15-19
17. Zhao ZJ, Geng JL, Chang ZF, Chen SM, Deng CM, Jiang T, Qin W, Lam JWY, Kwok HS, Qiu HY, Liu B and Tang BZ. A tetraphenylethene-based red luminophor for an efficient non-doped electroluminescence device and cellular imaging. J Mater Chem, 2012, 22:11018-11021
18. Li HK, Mei J, Wang J, Zhang S, Zhao QL, Wei Q, Qin AJ, Sun JZ, Tang BZ. Facile synthesis of poly(aroxycarbonyltriazole)s with aggregation-induced emission characteristics by metal-free click polymerization. Sci China Chem, 2011, 54:611-616
19. Qin AJ, Zhang Y, Han N, Mei J, Sun JZ, Fan WM, Tang BZ. Preparation and self-assembly of amphiphilic polymer with aggregation-induced emission characteristics. Sci China Chem, 2012, 55:772-778
20. Qian J, Li X, Wei M, Gao XW, Xu ZP, and He SL. Bio-molecule-conjugated fluorescent organically modified silica nanoparticles as optical probes for cancer cell imaging. Opt Express, 2008, 16:19568-19578
21. Qian J, Gharibi A, He S. Colloidal mesoporous silica nanoparticles with protoporphyrin IX encapsulated for photodynamic therapy. J Biomed Opt, 2009, 14:014012