Single point mutations in ATP synthase compensate for mitochondrial genome loss in trypanosomes

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 36, 2013, Pages 14741-14746

  Dean, Samuel ^a,b   Gould, Matthew K ^a   Dewar, Caroline E ^a   Schnaufer, Achim C ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Dourine; Dyskinetoplastic; Mitochondrial DNA; RNA editing; Surra

Indexed keywords

ADENINE NUCLEOTIDE TRANSLOCASE; AMINO ACID; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; CARBONYL CYANIDE 4 (TRIFLUOROMETHOXY)PHENYLHYDRAZONE; F1F0-ATP SYNTHASE; KINETOPLAST DNA; PROTEIN SUBUNIT; PROTON IONOPHORE; PROTOZOAL PROTEIN;

ARTICLE; CONTROLLED STUDY; GENE EXPRESSION REGULATION; MITOCHONDRIAL GENOME; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; TRYPANOSOMA; AMINO ACID SEQUENCE; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; FLOW CYTOMETRY; GENETICS; GLOSSINIDAE; HUMAN; METABOLISM; MOLECULAR GENETICS; PARASITOLOGY; PHYSIOLOGY; PROTEIN CONFORMATION; PROTEIN SUBUNIT; SEQUENCE HOMOLOGY; WESTERN BLOTTING;

ANIMALIA; GLOSSINA (GENUS); TRYPANOSOMA BRUCEI;

AMINO ACID SEQUENCE; ANIMALS; BLOTTING, WESTERN; CARBONYL CYANIDE P-TRIFLUOROMETHOXYPHENYLHYDRAZONE; DNA, KINETOPLAST; FLOW CYTOMETRY; GENOME, MITOCHONDRIAL; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIAL PROTON-TRANSLOCATING ATPASES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; POINT MUTATION; PROTEIN CONFORMATION; PROTEIN SUBUNITS; PROTON IONOPHORES; PROTOZOAN PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; TRYPANOSOMA; TSETSE FLIES;

EID: 84883418344     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1305404110     Document Type: Article

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