Association of epicardial adipose tissue with cardiometabolic risk and metabolic syndrome in patients with rheumatoid arthritis

Arthritis Care and Research

Volumn 65, Issue 9, 2013, Pages 1410-1415

  Ormseth, Michelle J ^a   Lipson, Aliza ^b   Alexopoulos, Nikolaos ^b   Hartlage, Gregory R ^b   Oeser, Annette M ^a   Bian, Aihua ^a   Gebretsadik, Tebeb ^a   Shintani, Ayumi ^a   Raggi, Paolo ^b   Stein, C Michael ^a  

^a VANDERBILT UNIVERSITY   (United States)

^b EMORY UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPOCYTOKINE; CORTICOSTEROID; CYTOKINE; HIGH DENSITY LIPOPROTEIN; HOMOCYSTEINE; INTERLEUKIN 6; METHOTREXATE; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA INHIBITOR;

ADIPOSE TISSUE; ADULT; ANTHROPOMETRIC PARAMETERS; ARTICLE; CARDIOMETABOLIC RISK; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; CORONARY ARTERY CALCIUM SCORE; EPICARDIAL ADIPOSE TISSUE; FEMALE; HOMEOSTASIS; HUMAN; HYPERTENSION; INSULIN RESISTANCE; INTRAABDOMINAL FAT; MAJOR CLINICAL STUDY; MALE; METABOLIC SYNDROME X; RHEUMATOID ARTHRITIS; SMOKING;

ADIPOSE TISSUE; ARTHRITIS, RHEUMATOID; BODY FAT DISTRIBUTION; CARDIOVASCULAR DISEASES; COHORT STUDIES; FEMALE; HUMANS; INTRA-ABDOMINAL FAT; MALE; METABOLIC SYNDROME X; MIDDLE AGED; PERICARDIUM; RISK FACTORS;

EID: 84883385987     PISSN: 2151464X     EISSN: 21514658     Source Type: Journal    
DOI: 10.1002/acr.22027     Document Type: Article

References (42)

1. Chung CP, Oeser A, Raggi P, Gebretsadik T, Shintani AK, Sokka T, et al. Increased coronary-artery atherosclerosis in rheumatoid arthritis: relationship to disease duration and cardiovascular risk factors. Arthritis Rheum 2005; 52: 3045-53.
2. Solomon DH, Karlson EW, Rimm EB, Cannuscio CC, Mandl LA, Manson JE, et al. Cardiovascular morbidity and mortality in women diagnosed with rheumatoid arthritis. Circulation 2003; 107: 1303-7.
3. Myllykangas-Luosujarvi RA, Aho K, Isomaki HA,. Mortality in rheumatoid arthritis. Semin Arthritis Rheum 1995; 25: 193-202.
4. Chung CP, Oeser A, Solus JF, Avalos I, Gebretsadik T, Shintani A, et al. Prevalence of the metabolic syndrome is increased in rheumatoid arthritis and is associated with coronary atherosclerosis. Atherosclerosis 2008; 196: 756-63.
5. Santos MJ, Vinagre F, Canas da Silva J, Gil V, Fonseca JE,. Body composition phenotypes in systemic lupus erythematosus and rheumatoid arthritis: a comparative study of Caucasian female patients. Clin Exp Rheumatol 2011; 29: 470-6.
6. Smith JD, Borel AL, Nazare JA, Haffner SM, Balkau B, Ross R, et al. Visceral adipose tissue indicates the severity of cardiometabolic risk in patients with and without type 2 diabetes: results from the INSPIRE ME IAA study. J Clin Endocrinol Metab 2012; 97: 1517-25.
7. Giles JT, Allison M, Blumenthal RS, Post W, Gelber AC, Petri M, et al. Abdominal adiposity in rheumatoid arthritis: association with cardiometabolic risk factors and disease characteristics. Arthritis Rheum 2010; 62: 3173-82.
8. Xu Y, Cheng X, Hong K, Huang C, Wan L,. How to interpret epicardial adipose tissue as a cause of coronary artery disease: a meta-analysis. Coron Artery Dis 2012; 23: 227-33.
9. Yerramasu A, Dey D, Venuraju S, Anand DV, Atwal S, Corder R, et al. Increased volume of epicardial fat is an independent risk factor for accelerated progression of sub-clinical coronary atherosclerosis. Atherosclerosis 2012; 220: 223-30.
10. Ohman MK, Luo W, Wang H, Guo C, Abdallah W, Russo HM, et al. Perivascular visceral adipose tissue induces atherosclerosis in apolipoprotein E deficient mice. Atherosclerosis 2011; 219: 33-9.
11. Corradi D, Maestri R, Callegari S, Pastori P, Goldoni M, Luong TV, et al. The ventricular epicardial fat is related to the myocardial mass in normal, ischemic and hypertrophic hearts. Cardiovasc Pathol 2004; 13: 313-6.
12. Graner M, Seppala-Lindroos A, Rissanen A, Hakkarainen A, Lundbom N, Kaprio J, et al. Epicardial fat, cardiac dimensions, and low-grade inflammation in young adult monozygotic twins discordant for obesity. Am J Cardiol 2012; 109: 1295-302.
13. Baker AR, Silva NF, Quinn DW, Harte AL, Pagano D, Bonser RS, et al. Human epicardial adipose tissue expresses a pathogenic profile of adipocytokines in patients with cardiovascular disease. Cardiovasc Diabetol 2006; 5: 1.
14. Mazurek T, Zhang L, Zalewski A, Mannion JD, Diehl JT, Arafat H, et al. Human epicardial adipose tissue is a source of inflammatory mediators. Circulation 2003; 108: 2460-6.
15. Alexopoulos N, McLean DS, Janik M, Arepalli CD, Stillman AE, Raggi P,. Epicardial adipose tissue and coronary artery plaque characteristics. Atherosclerosis 2010; 210: 150-4.
16. Janik M, Hartlage G, Alexopoulos N, Mirzoyev Z, McLean DS, Arepalli CD, et al. Epicardial adipose tissue volume and coronary artery calcium to predict myocardial ischemia on positron emission tomography-computed tomography studies. J Nucl Cardiol 2010; 17: 841-7.
17. Iacobellis G, Leonetti F,. Epicardial adipose tissue and insulin resistance in obese subjects. J Clin Endocrinol Metab 2005; 90: 6300-2.
18. Iacobellis G, Assael F, Ribaudo MC, Zappaterreno A, Alessi G, Di Mario U, et al. Epicardial fat from echocardiography: a new method for visceral adipose tissue prediction. Obes Res 2003; 11: 304-10.
19. Yorgun H, Canpolat U, Hazirolan T, Ates AH, Sunman H, Dural M, et al. Increased epicardial fat tissue is a marker of metabolic syndrome in adult patients. Int J Cardiol 2013; 165: 308-13.
20. Wang TD, Lee WJ, Shih FY, Huang CH, Chang YC, Chen WJ, et al. Relations of epicardial adipose tissue measured by multidetector computed tomography to components of the metabolic syndrome are region-specific and independent of anthropometric indexes and intraabdominal visceral fat. J Clin Endocrinol Metab 2009; 94: 662-9.
21. Pierdomenico SD, Pierdomenico AM, Neri M, Cuccurullo F,. Epicardial adipose tissue and metabolic syndrome in hypertensive patients with normal body weight and waist circumference. Am J Hyperten 2011; 24: 1245-9.
22. Iacobellis G, Sharma AM,. Epicardial adipose tissue as new cardio-metabolic risk marker and potential therapeutic target in the metabolic syndrome. Curr Pharm Design 2007; 13: 2180-4.
23. Sacks HS, Fain JN, Cheema P, Bahouth SW, Garrett E, Wolf RY, et al. Inflammatory genes in epicardial fat contiguous with coronary atherosclerosis in the metabolic syndrome and type 2 diabetes: changes associated with pioglitazone. Diabetes Care 2011; 34: 730-3.
24. Chung CP, Oeser A, Raggi P, Sokka T, Pincus T, Solus JF, et al. Lipoprotein subclasses determined by nuclear magnetic resonance spectroscopy and coronary atherosclerosis in patients with rheumatoid arthritis. J Rheum 2010; 37: 1633-8.
25. Chung CP, Oeser A, Solus JF, Gebretsadik T, Shintani A, Avalos I, et al. Inflammation-associated insulin resistance: differential effects in rheumatoid arthritis and systemic lupus erythematosus define potential mechanisms. Arthritis Rheum 2008; 58: 2105-12.
26. Rho YH, Chung CP, Oeser A, Solus J, Asanuma Y, Sokka T, et al. Inflammatory mediators and premature coronary atherosclerosis in rheumatoid arthritis. Arthritis Rheum 2009; 61: 1580-5.
27. Solus J, Chung CP, Oeser A, Avalos I, Gebretsadik T, Shintani A, et al. Amino-terminal fragment of the prohormone brain-type natriuretic peptide in rheumatoid arthritis. Arthritis Rheum 2008; 58: 2662-9.
28. Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988; 31: 315-24.
29. Prevoo ML, van 't Hof MA, Kuper HH, van Leeuwen MA, van de Putte LB, van Riel PL,. Modified disease activity scores that include twenty-eight-joint counts: development and validation in a prospective longitudinal study of patients with rheumatoid arthritis. Arthritis Rheum 1995; 38: 44-8.
30. Executive summary of the third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III). JAMA 2001; 285: 2486-97.
31. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC,. Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985; 28: 412-9.
32. Greif M, Becker A, von Ziegler F, Lebherz C, Lehrke M, Broedl UC, et al. Pericardial adipose tissue determined by dual source CT is a risk factor for coronary atherosclerosis. Arterioscler Thromb Vasc Biol 2009; 29: 781-6.
33. Lipson A, Alexopoulos N, Hartlage GR, Arepalli C, Oeser A, Bian A, et al. Epicardial adipose tissue is increased in patients with systemic lupus erythematosus. Atherosclerosis 2012; 223: 389-93.
34. Iacobellis G, Pellicelli AM, Grisorio B, Barbarini G, Leonetti F, Sharma AM, et al. Relation of epicardial fat and alanine aminotransferase in subjects with increased visceral fat. Obesity (Silver Spring) 2008; 16: 179-83.
35. Singh N, Singh H, Khanijoun HK, Iacobellis G,. Echocardiographic assessment of epicardial adipose tissue: a marker of visceral adiposity. McGill Med J 2007; 10: 26-30.
36. Riederer M, Erwa W, Zimmermann R, Frank S, Zechner R,. Adipose tissue as a source of nicotinamide N-methyltransferase and homocysteine. Atherosclerosis 2009; 204: 412-7.
37. Masaki T, Anan F, Anai M, Higuchi K, Tsubone T, Gotoh K, et al. Hyperhomocysteinemia is associated with visceral adiposity in Japanese patients with type 2 diabetes mellitus. Diabetes Res Clin Pr 2007; 77: 168-73.
38. Kim JH, Shim KW, Yoon YS, Lee SY, Kin SS, Oh SW,. Cigarette smoking increases abdominal and visceral obesity but not overall fatness: an observational study. PLoS One 2012; 7: e45815.
39. De Vos AM, Prokop M, Roos CJ, Meijs MF, van der Schouw YT, Rutten A, et al. Peri-coronary epicardial adipose tissue is related to cardiovascular risk factors and coronary artery calcification in post-menopausal women. Eur Heart J 2008; 29: 777-83.
40. Shibasaki I, Nishikimi T, Mochizuki Y, Yamada Y, Yoshitatsu M, Inoue Y, et al. Greater expression of inflammatory cytokines, adrenomedullin, and natriuretic peptide receptor-C in epicardial adipose tissue in coronary artery disease. Regul Peptides 2010; 165: 210-7.
41. Sarin S, Wenger C, Marwaha A, Qureshi A, Go BD, Woomert CA, et al. Clinical significance of epicardial fat measured using cardiac multislice computed tomography. Am J Cardiol 2008; 102: 767-71.
42. Falk E, Shah PK, Fuster V,. Coronary plaque disruption. Circulation 1995; 92: 657-71.