Using one-step nucleic acid amplification (OSNA) for intraoperative detection of lymph node metastasis in breast cancer patients avoids second surgery and accelerates initiation of adjuvant therapy

Annals of Oncology

Volumn 24, Issue 9, 2013, Pages 2305-2309

  Klingler, S ^a,b   Marchal, F ^a,b,c   Rauch, P ^a   Kenouchi, O ^a   Chretien A S ^a,b   Genin, P ^a   Leroux, A ^a,b,c   Merlin, J L ^a,b,c  

^a Institut de Cancérologie de Lorraine Alexis Vautrin   (France)

^b UNIVERSITÉ DE LORRAINE   (France)

^c CENTRE DE RECHERCHE EN AUTOMATIQUE DE NANCY   (France)

Author keywords

Breast cancer; CK19 mRNA; Intraoperative assay; OSNA; PCR assay; Sentinel lymph node

Indexed keywords

DYE; PATENT BLUE DYE; RADIOISOTOPE; RHENIUM SULFUR TC 99M; UNCLASSIFIED DRUG;

ARTICLE; AXILLARY LYMPH NODE; BREAST CANCER; CANCER ADJUVANT THERAPY; CANCER CHEMOTHERAPY; CANCER HORMONE THERAPY; CANCER PATIENT; CANCER RADIOTHERAPY; CANCER STAGING; COHORT ANALYSIS; COMPARATIVE STUDY; CONTROLLED STUDY; DIAGNOSTIC TEST ACCURACY STUDY; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; INTRAOPERATIVE PERIOD; LYMPH NODE DISSECTION; MACROMETASTASIS; MAJOR CLINICAL STUDY; MICROMETASTASIS; NON SENTINEL LYMPH NODE METASTASIS; NUCLEIC ACID AMPLIFICATION; ONE STEP NUCLEIC ACID AMPLIFICATION; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SENTINEL LYMPH NODE METASTASIS; THERAPY DELAY;

BREAST CANCER; CK19 MRNA; INTRAOPERATIVE ASSAY; OSNA; PCR ASSAY; SENTINEL LYMPH NODE;

AXILLA; BREAST NEOPLASMS; CHEMOTHERAPY, ADJUVANT; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; INTRAOPERATIVE CARE; INTRAOPERATIVE PERIOD; LYMPH NODES; LYMPHATIC METASTASIS; MIDDLE AGED; NUCLEIC ACID AMPLIFICATION TECHNIQUES; RETROSPECTIVE STUDIES; RNA, MESSENGER; SENTINEL LYMPH NODE BIOPSY;

EID: 84883377348     PISSN: 09237534     EISSN: 15698041     Source Type: Journal    
DOI: 10.1093/annonc/mdt160     Document Type: Article

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