Light-mediated in cell downregulation of G-quadruplex-containing genes using a photo-caged ligand

Chemical Communications

Volumn 49, Issue 76, 2013, Pages 8453-8455

  Murat, Pierre ^a   Gormally, Michael V ^a   Sanders, Debbie ^b   Antonio, Marco Di ^a   Balasubramanian, Shankar ^a,b,c  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOQUINOLINES; ANTINEOPLASTIC AGENTS; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; DRUG SCREENING ASSAYS, ANTITUMOR; G-QUADRUPLEXES; GENES, SRC; HUMANS; LIGANDS; MOLECULAR STRUCTURE; NEOPLASMS, GLANDULAR AND EPITHELIAL; PHOTOCHEMICAL PROCESSES; PICOLINIC ACIDS; STRUCTURE-ACTIVITY RELATIONSHIP; ULTRAVIOLET RAYS;

GUANINE QUADRUPLEX; PHOTOSENSITIZING AGENT; PYRIDOSTATIN; UNCLASSIFIED DRUG;

ARTICLE; DOWN REGULATION; GENE EXPRESSION; HUMAN; HUMAN CELL; ONCOGENE SRC; PHOTOTHERAPY; STRUCTURE ANALYSIS; TRANSCRIPTION REGULATION; TUMOR GROWTH; ULTRAVIOLET RADIATION;

EID: 84883372353     PISSN: 13597345     EISSN: 1364548X     Source Type: Journal    
DOI: 10.1039/c3cc44737e     Document Type: Article

References (26)

1. M. Demeunynck, C. Bailly and W. D. Wilson, DNA and RNA Binders, From Small Molecules to Drugs, Wiley-VCH, 2003
2. S. Balasubramanian, L. H. Hurley, S. Neidle, Nat. Rev. Drug Discovery, 2011, 10, 261
3. S. Kumari, A. Bugaut, J. L. Huppert, S. Balasubramanian, Nat. Chem. Biol., 2007, 3, 218
4. J. Zhao, A. Bacolla, G. Wang, K. M. Vasquez, Cell Mol. Life Sci., 2010, 67, 43
5. A. Siddiqui-Jain, C. L. Grand, D. J. Bearss, L. H. Hurley, Proc. Natl. Acad. Sci. U. S. A., 2002, 99, 11593
6. M. Bejugam, S. Sewitz, P. S. Shirude, R. Rodriguez, R. Shahid, S. Balasubramanian, J. Am. Chem. Soc., 2007, 129, 12926
7. D. Monchaud, M.-P. Teulade-Fichou, Org. Biomol. Chem., 2008, 6, 627
8. T.-M. Ou, Y.-J. Lu, J.-H. Tan, Z.-S. Huang, K.-Y. Wong, L.-Q. Gu, ChemMedChem, 2008, 3, 690
9. R. Rodriguez, S. Müller, J. A. Yeoman, C. Trenteseaux, J.-F. Riou, S. Balasubramanian, J. Am. Chem. Soc., 2008, 130, 15758
10. R. Rodriguez, K. Miller, J. V. Forment, C. R. Bradshaw, M. Nikan, S. Britton, T. Oelschlaegel, B. Xhemlace, S. Balasubramanian, S. P. Jackson, Nat. Chem. Biol., 2012, 8, 301
11. G. Biffi, D. Tannahill, J. McCafferty, S. Balasubramanian, Nat. Chem., 2013, 5, 182
12. G. Mayer, A. Heckel, Angew. Chem., Int. Ed., 2006, 45, 4900
13. A. Deiters, ChemBioChem, 2010, 11, 47
14. G. C. R. Ellis-Davies, Nat. Methods, 2007, 4, 619
15. F. G. Cruz, J. T. Koh, K. H. Link, J. Am. Chem. Soc., 2000, 122, 8777
16. K. H. Link, Y. Shi, J. T. Koh, J. Am. Chem. Soc., 2005, 127, 13088
17. S. Müller, D. A. Sanders, M. Di Antonio, S. Matsis, J.-F. Riou, R. Rodriguez, S. Balasubramanian, Org. Biomol. Chem., 2012, 10, 6537
18. T. Nakamura, K. Iida, M. Tera, K. Shin-ya, H. Seimiya, K. Nagasawa, ChemBioChem, 2012, 13, 774
19. M. I. Sánchez, O. Vázquez, M. E. Vázquez, J. L. Mascareñas, Chem. Commun., 2011, 47, 11107
20. M. I. Sánchez, J. Martinez-Costas, F. Gonzalez, M. A. Bermudez, M. E. Vázquez, J. L. Mascareñas, ACS Chem. Biol., 2012, 7, 1276
21. Y. V. Il'ichev, M. A. Schwörer, J. Wirz, J. Am. Chem. Soc., 2004, 126, 4581
22. R. Ishizawar, S. J. Parsons, Cancer Cell, 2004, 6, 209
23. J.-L. Mergny, L. Lacroix, M.-P. Teulade-Fichou, C. Hounsou, L. Guittat, M. Hoarau, P. B. Arimondo, J.-P. Vigneron, J.-M. Lehn, J.-F. Riou, T. Garestier, C. Hélene, Proc. Natl. Acad. Sci. U. S. A., 2001, 98, 3062
24. P. Murat, Y. Singh, E. Defrancq, Chem. Soc. Rev., 2011, 40, 5293
25. G. Niu, T. Bowman, M. Huang, S. Shivers, D. Reintgen, A. Daud, A. Chang, A. Kraker, R. Jove, H. Yu, Oncogene, 2002, 21, 7001
26. R. B. Irby, Oncogene, 2000, 19, 5636