Inhibitory effect of 10-hydroxydecanoic acid on lipopolysaccharide-induced nitric oxide production via translational downregulation of interferon regulatory factor-1 in RAW264 murine macrophages

Biomedical Research (Japan)

Volumn 34, Issue 4, 2013, Pages 205-214

  Takahashi, Keita ^a   Sugiyama, Tsuyoshi ^a   Tokoro, Shunji ^a   Neri, Paola ^a   Mori, Hiroshi ^a  

^a GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

10 HYDROXYDECANOIC ACID; DECANOIC ACID DERIVATIVE; DNA; GAMMA INTERFERON INDUCIBLE PROTEIN 10; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INITIATION FACTOR 4E BINDING PROTEIN 1; INTERFERON REGULATORY FACTOR 1; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 2; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; NITRIC OXIDE; PROTEIN KINASE B; STAT1 PROTEIN; STAT2 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DNA RESPONSIVE ELEMENT; DOWN REGULATION; MACROPHAGE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS INHIBITION; RNA TRANSLATION;

ANIMALS; CARRIER PROTEINS; CELL LINE; CYTOKINES; FATTY ACIDS, MONOUNSATURATED; GENE EXPRESSION REGULATION; INTERFERON REGULATORY FACTOR-1; INTERFERON REGULATORY FACTORS; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN BIOSYNTHESIS; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; STAT2 TRANSCRIPTION FACTOR;

EID: 84883356043     PISSN: 03886107     EISSN: 1880313X     Source Type: Journal    
DOI: 10.2220/biomedres.34.205     Document Type: Article

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