Does high-dose radiotherapy benefit palliative lung cancer patients?: An intradepartmental comparison of two dose regimens

Strahlentherapie und Onkologie

Volumn 189, Issue 9, 2013, Pages 771-776

  Schroder C ^a,b   Ivo, M ^b   Buchali, A ^a  

^a Ruppiner Kliniken GmbH   (Germany)

^b JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

Dysphagia; Performance status; Quality of life; Survival; Toxicity

Indexed keywords

ADULT; AGED; ARTICLE; CANCER PALLIATIVE THERAPY; CANCER PATIENT; CANCER RADIOTHERAPY; COMPARATIVE STUDY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; OVERALL SURVIVAL; RADIATION DOSE; RADIATION DOSE FRACTIONATION; SURVIVAL TIME; TREATMENT OUTCOME;

ADULT; AGED; AGED, 80 AND OVER; BRONCHIAL NEOPLASMS; DOSE FRACTIONATION; DOSE-RESPONSE RELATIONSHIP, RADIATION; FEMALE; GERMANY; HUMANS; INCIDENCE; MALE; MIDDLE AGED; PALLIATIVE CARE; RISK FACTORS; SURVIVAL ANALYSIS; SURVIVAL RATE; TREATMENT OUTCOME;

EID: 84883307865     PISSN: 01797158     EISSN: 1439099X     Source Type: Journal    
DOI: 10.1007/s00066-013-0360-z     Document Type: Article

References (27)

1. Abratt RP, Shepherd LJ, Salton DG (1995) Palliative radiation for stage 3 non-small cell lung cancer - a prospective study of two moderately high dose regimens. Lung Cancer 13:137-143
2. Appold S, Baumann M, Neidt F et al (1999) Ergebnisse der Bestrahlung inoperabler nichtkleinzelliger Bronchialkarzinome im Stadium III mit 25 Gy in fünf Fraktionen. Strahlenther Onkol 175:267-270
3. Bezjak A, Dixon P, Brundage M et al (2002) Randomized phase iii trial of single versus fractionated thoracic radiation in the palliation of patients with lung cancer (NCIC CTG SC.15). Int J Radiat Oncol Biol Phys 54:719-728
4. Budach W, Belka C (2004) Palliative percutaneous radiotherapy in non-small cell lung cancer. Lung Cancer 45:239-245
5. Cross CK, Berman S, Buswell L et al (2004) Prospective study of palliative hypofractionated radiotherapy (8.5 Gy × 2) for patients with symptomatic non-small cell lung cancer. Int J Radiat Oncol Biol Phys 58:1098-1105
6. De Ruysscher D, Van Meerbeeck J, Vandecasteele K et al (2012) Radiation-induced oesophagitis in lung cancer patients. Strahlenther Onkol 188:564-567
7. Erridge SC, Gaze MN, Prize A et al (2005) Symptom control and quality of life in people with lung cancer: a randomized trial of two palliative radiotherapy fractionation schedules. Clin Oncol (R Coll Radiol) 17:61-67
8. Fairchild A, Harris K, Barnes E et al (2008) Palliative thoracic radiotherapy for lung cancer: a systematic review. J Clin Oncol 26:4001-4011
9. Fowler JF (1992) Brief summary of radiobiological principles in fractionated radiotherapy. Semin Radiat Oncol 2:16-21
10. Kramer GW, Wanders SL, Noordijk EM et al (2005) Results of the dutch national study of the palliative effect of irradiation using two different treatment schemes for non-small cell lung cancer. J Clin Oncol 23:2962-2970
11. Lupattelli M, Maranzano E, Bellavita R et al (2000) Short-course palliative radiotherapy in non-small cell lung cancer: results of a prospective study. Am J Clin Oncol 23:89-93
12. Mac Manus MP, Matthews JP, Wada M et al (2006) Unexpected long-term survival after low-dose palliative radiotherapy for non-small cell lung cancer. Cancer 106:1110-1116
13. Maurer J, Hipp M, Schäfer C et al (2011) Dysphagia. Strahlenther Onkol 187:744-749
14. Medical Research Council Lung Cancer Working Party (1991) Inoperable non-small cell lung cancer: a medical research council randomized trial of palliative radiotherapy with two fractions or ten fractions. Br J Cancer 63:265-270
15. Medical Research Council Lung Cancer Working Party (1992) A Medical Research Council (MRC) randomized trial of palliative radiotherapy with two fractions or a single fraction in patients with inoperable non-small cell lung cancer (NSCLC) and poor performance status. Br J Cancer 65:935-941
16. Medical Research Council Lung Cancer Working Party (1996) Randomized trial of palliative two-fraction versus more intensive 13-fraction radiotherapy for patients with inoperable non-small cell lung cancer and good performance status. Clin Oncol (R Coll Radiol) 8:167-175
17. Nestle U, Nieder C, Walter K et al (2000) A palliative accelerated irradiation regimen for advanced non-small cell lung cancer vs. conventionally fractionated 60 Gy: results of a randomized equivalence study. Int J Radiat Oncol Biol Phys 48:95-103
18. Oken MM, Creech, RH, Tormey DC et al (1982) Toxicity and response criteria of the eastern cooperative oncology group. Am J Clin Oncol 5:649-655
19. Plataniotis GA, Kouvaris JR, Dardoufas C et al (2002) A short radiotherapy course for locally advanced non-small cell lung cancer (NSCLC). Effective palliation and patients' convenience. Lung Cancer 35:203-207
20. Rees GJG, Devrell CE, Barley VL et al (1997) Palliative radiotherapy for lung cancer: two versus five fractions. Clin Oncol (R Coll Radiol) 9:90-95
21. Reinfuss M, Glinski B, Kowalska T et al (1999) Radiothérapie du Cancer Bronchique non à Petites Cellules de Stade III, Inoperable, Asymptomatique. Résultats Définitifs d'un Essai Prospectif Randomisé (240 Patients). Cancer/Radiothérapie 3:475-479
22. Rodrigues G, Videtic G, Sur R et al (2011) Palliative thoracic radiotherapy in lung cancer: an american society for radiation oncology evidence-based clinical practice guideline. Pract Radiat Oncol 1:60-71
23. Senkus-Konefka E, Dziadziuszko R, Bednaruk-Młyński E et al (2005) A prospective, randomized study to compare two palliative radiotherapy schedules for non-small cell lung cancer (NSCLC). Br J Cancer 92:1038-1045
24. Simpson JR, Francis ME, Perez-Tamayo R et al (1985) Palliative radiotherapy for inoperable carcinoma of the lung: final report of a RTOG multi-institutional Trial Int J Radiat Oncol Biol Phys 11:751-758
25. Sundstrøm S, Bremnes R, Aasebø U et al (2004) Hypofractionated palliative radiotherapy (17 Gy per two fractions) in advanced non-small cell lung carcinoma is comparable to standard fractionation for symptom control and survival: a national phase III trial. J Clin Oncol 22:801-810
26. Toy E, Macbeth F, Coles B et al (2003) Palliative thoracic radiotherapy for non-small cell lung cancer. Am J Clin Oncol 26:112-120
27. Oorschot B van, Schuler M, Simon A et al (2011) Patterns of care and course of symptoms in palliative radiotherapy. A multicenter pilot study analysis. Strahlenther Onkol 187:461-466