Predicting walking-induced oxygen desaturations in COPD patients: A statistical model

Respiratory Care

Volumn 58, Issue 9, 2013, Pages 1495-1503

  Crisafulli, Ernesto ^a   Iattoni, Andrea ^a   Venturelli, Elena ^a   Siscaro, Gherardo ^a   Beneventi, Claudio ^a   Cesario, Alfredo ^a,b   Clini, Enrico M ^a,c  

^a UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^b CATHOLIC UNIVERSITY   (Italy)

^c Villa Pineta Hospital   (Italy)

Author keywords

6 min walk test; Community healthcare; COPD; Decision making; Oxygen desaturation; Risk score

Indexed keywords

OXYGEN;

6 MIN WALK TEST; ANALYTIC METHOD; ARTERIAL BLOOD; ARTERIAL OXYGEN SATURATION; ARTERIAL OXYGEN TENSION; ARTICLE; BLOOD SAMPLING; CALIBRATION; CHI SQUARE TEST; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL TRIAL; COHORT ANALYSIS; COMMUNITY CARE; CONTROLLED STUDY; DIAGNOSTIC TEST; DIAGNOSTIC TEST ACCURACY STUDY; FEMALE; FORCED EXPIRATORY VOLUME; HOSMER LEMESHOW GOODNESS OF FIT TEST; HOSPITAL ADMISSION; HOSPITAL PATIENT; HUMAN; MAJOR CLINICAL STUDY; MALE; OUTPATIENT; OXYGEN DESATURATION; PATIENT CODING; PATIENT MONITORING; PREDICTION; PROSPECTIVE STUDY; RECEIVER OPERATING CHARACTERISTIC; REGRESSION ANALYSIS; REHABILITATION CARE; REST; RISK ASSESSMENT; SCORING SYSTEM; STATISTICAL MODEL; SYMPTOM; VALIDATION STUDY; WALKING;

6-MIN WALK TEST; COMMUNITY HEALTHCARE; COPD; DECISION MAKING; OXYGEN DESATURATION; RISK SCORE;

AGED; AGED, 80 AND OVER; EXERCISE TEST; FEMALE; HUMANS; MALE; MIDDLE AGED; MODELS, STATISTICAL; OXIMETRY; OXYGEN; PROGNOSIS; PROSPECTIVE STUDIES; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; REGRESSION ANALYSIS; RISK ASSESSMENT; ROC CURVE; SPIROMETRY; WALKING;

EID: 84883306797     PISSN: 00201324     EISSN: 19433654     Source Type: Journal    
DOI: 10.4187/respcare.02321     Document Type: Article

References (35)

1. Robinson CW, White DP, Zwillich CW. Relationship of respiratory drives to dyspnea and exercise performance in chronic obstructive pulmonary disease. Am Rev Respir Dis 1987;136(5): 1084-1090.
2. van Meerhaeghe A, Sergysels R. Control of breathing during exercise in patients with chronic airflow limitation with and without hypercapnia. Chest 1983;84(5):565-570.
3. Soguel Schenkel N, Burdet L, de Muralt B, Fitting JW. Oxygen saturation during daily activities in chronic obstructive pulmonary disease. Eur Respir J 1996;9(12):2584-2589.
4. Palange P, Forte S, Onorati P, Manfredi F, Serra P, Carlone S. Ventilatory and metabolic adaptations to walking and cycling in patients with COPD. J Appl Physiol 2000;88(5):1715-1720.
5. American Thoracic Society. Guidelines for the six-minute walk test. Am J Respir Crit Care Med 2002;166(1):111-117.
6. Troosters T, Vilaro J, Rabinovich R, Casas A, Barbera JA, Rodriguez-Roisin R, Roca J. Physiological responses to the 6-min walk test in patients with chronic obstructive pulmonary disease. Eur Respir J 2002;20(3):564-569.
7. Clini EM, Crisafulli E. Exercise capacity as a pulmonary rehabilitation outcome. Respiration 2009;77(2):121-128.
8. Spence DP, Hay JG, Carter J, Pearson MG, Calverley PM. Oxygen desaturation and breathlessness during corridor walking in chronic obstructive pulmonary disease: effect of oxitropium bromide. Thorax 1993;48(11):1145-1150.
9. Turner SE, Eastwood PR, Cečins NM, Hillman DR, Jenkins SC. Physiologic responses to incremental and self paced exercise in COPD. A comparison of three tests. Chest 2004;126(3):766-773.
10. Poualin M, Durand F, Palomba B, Ceugniet F, Desplan J, Varray A, Préfaut C. Six-minute walk testing is more sensitive than maximal incremental cycle testing for detecting oxygen desaturation in patients with COPD. Chest 2003;123(5):1401-1407.
11. Escourrou PJL, Delaperche MF, Visseaux A. Reliability of pulse oximetry during exercise in pulmonary patients. Chest 1990;97(3): 635-638.
12. Takigawa N, Tada A, Soda R, Date H, Yamashita M, Endo S, et al. Distance and oxygen desaturation in 6-min walk test predict prognosis in COPD patients. Respir Med 2007;101(3):561-567.
13. Casanova C, Cote C, Marin JM, Pinto-Plata V, de Torres JP, Aguirre-Jaíme A et al. Distance and oxygen desaturation during the 6-min walk test as predictors of long-term mortality in patients with COPD. Chest 2008;134(4):746-752.
14. National Clinical Guideline Centre. Chronic obstructive pulmonary disease: management of chronic obstructive pulmonary disease in adults in primary and secondary care, 2010. http://www.ncgc.ac.uk/ Guidelines/Published/20. Accessed June 21, 2013.
15. Jones R, Gruffydd-Jones K, Pinnock H, Peffers SJ, Lawrence J, Scullion J et al. Summary of the consultation on a strategy for services for chronic obstructive pulmonary disease (COPD) in England. Prim Care Respir J 2010;19(Suppl 2):S1-S17.
16. Kocks JW, Asijee GM, Tsiligianni IG, Kerstjens HA, van der Molen T. Functional status measurement in COPD: a review of available methods and their feasibility in primary care. Prim Care Respir J 2011;20(3):269-275.
17. Global Initiative for Chronic Obstructive Pulmonary Disease (GOLD). Global strategy for the diagnosis, management and prevention of chronic obstructive pulmonary disease. http://www.goldcopd.org/guidelinesglobal- strategy-for-diagnosis-management.html. Accessed June 21, 2013.
18. Lohman TG, Roche AF, Martorell R. Anthropometric standardization reference manual. Champaign, IL: Human Kinetics; 1988.
19. Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 1987;40(5):373-383.
20. Quanjer PH, Tammeling GJ, Cotes JE. Lung volumes and forced ventilatory flows: report Working Party Standardization of Lung Function Tests, European Community for Steel and Coal, official statement of the European Respiratory Society Eur Respir J 1993; 16(Suppl):5-40.
21. Celli BR, Cote CG, Marin JM, Casanova C, Montes de Oca M, Mendez RA et al. The body-mass index, airflow obstruction, dyspnea, and exercise capacity index in chronic obstructive pulmonary disease. N Engl J Med 2004;350(10):1005-1012.
22. Puhan MA, Garcia-Aymerich J, Frey M, ter Riet G, Antó JM, Agustí AG et al. Expansion of the prognostic assessment of patients with chronic obstructive pulmonary disease: the updated BODE index and the ADO index. Lancet 2009;374(9691):704-711.
23. Knox AJ, Morrison JF, Muers MF. Reproducibility of walking test results in chronic obstructive airways disease. Thorax 1988;43(5): 388-392.
24. British Thoracic Society Working Group on Home Oxygen Services. Clinical component for the home oxygen service in England and Wales, January 2006. http://www.brit-thoracic.org.uk/Portals/ 0/Clinical%20Information/Home%20Oxygen%20Service/clinical%20 adultoxygenjan06.pdf. Accessed June 21, 2013.
25. Jones RC, Donaldson GC, Chavannes NH, Kida K, Dickson- Spillmann M, Harding S, et al. Derivation and validation of a composite index of severity in chronic obstructive pulmonary disease. The DOSE Index. Am J Respir Crit Care Med 2009;180(12):1189-1195.
26. Rassi A Jr, Rassi A, Little WC, Xavier SS, Rassi SG, Rassi AG, et al. Development and validation of a risk score for predicting death in Chagas' heart disease. N Engl J Med 2006;355(8):799-808.
27. Harrell FE Jr, Lee KL, Mark DB. Multivariable prognostic models: issues in developing models, evaluating assumptions and adequacy, and measuring and reducing errors. Stat Med 1996;15(4): 361-387.
28. Altman DG, Royston P. What do we mean by validating a prognostic model? Stat Med 2000;19(4):453-473.
29. Jenkins S, Cečins N. Six-minute walk test: observed adverse events and oxygen desaturation in a large cohort of patients with chronic lung disease. Intern Med J 2011;41(5):416-422.
30. Kelley MA, Panettieri RA, Krupinski AV. Resting single-breath diffusing capacity as a screening test for exercise-induced hypoxemia. Am J Med 1986;80(5):807-812.
31. Owens GR, Rogers RM, Pennock BE, Levin D. The diffusing capacity as a predictor of arterial oxygen desaturation during exercise in patients with chronic obstructive pulmonary disease. N Engl J Med 1984;310(19):1218-1221.
32. Hadeli KO, Siegel EM, Sherrill DL, Beck KC, Enright PL. Predictors of oxygen desaturation during submaximal exercise in 8,000 patients. Chest 2001;120(1):88-92.
33. Knower MT, Dunagan DP, Adair NE, Chin R Jr. Baseline oxygen saturation predicts exercise desaturation below prescription threshold in patients with chronic obstructive pulmonary disease. Arch Intern Med 2001;161(5):732-736.
34. Palange P, Ward SA, Carlsen KH, Casaburi R, Gallagher CG, Gosselink R; on behalf of ERS Task Force. Recommendations on the use of exercise testing in clinical practice. Eur Respir J 2007;29(1): 185-209.
35. King TE Jr. Clinical advances in the diagnosis and therapy of the interstitial lung diseases. Am J Respir Crit Care Med 2005;172(3): 268-279.