Enhanced levels of asymmetric dimethylarginine in a serum of middle age patients with myelodysplastic syndrome

Journal of Hematology and Oncology

Volumn 6, Issue 1, 2013, Pages

  Štikarová, Jana ^a   Suttnar, Jiří ^a   Pimková, Kristýna ^a   Chrastinová Mášová, Leona ^a   Čermák, Jaroslav ^a   Dyr, Jan E ^a  

^a INSTITUTE OF HEMATOLOGY AND BLOOD TRANSFUSION   (Czech Republic)

Author keywords

[No Author keywords available]

Indexed keywords

3,4 METHYLENEDIOXYAMPHETAMINE; CITRULLINE; FERRITIN; HOMOARGININE; IRON; MALONALDEHYDE; N(G),N(G) DIMETHYLARGININE; NITRIC OXIDE SYNTHASE; NITRITE; TRANSFERRIN; ARGININE; N,N-DIMETHYLARGININE;

ADULT; AMINO ACID BLOOD LEVEL; ARTICLE; CANCER PATIENT; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; FERRITIN BLOOD LEVEL; HUMAN; IRON BLOOD LEVEL; MALE; MIDDLE AGED; MYELODYSPLASTIC SYNDROME; OXIDATIVE STRESS; PATHOGENESIS; POSITIVE FEEDBACK; PROTEIN DEGRADATION; THERAPY EFFECT; TRANSFERRIN BLOOD LEVEL; ANALOGS AND DERIVATIVES; BLOOD; CASE CONTROL STUDY; PHYSIOLOGY;

ADULT; ARGININE; CASE-CONTROL STUDIES; FEMALE; HUMANS; MALE; MIDDLE AGED; MYELODYSPLASTIC SYNDROMES; OXIDATIVE STRESS;

EID: 84883304712     PISSN: None     EISSN: 17568722     Source Type: Journal    
DOI: 10.1186/1756-8722-6-58     Document Type: Article

References (11)

1. Oxidative stress and the myelodysplastic syndromes. Farquhar MJ, Bowen DT, Int J Hematol 2003 77 342 350 10.1007/BF02982641 12774921 (Pubitemid 37121829)
2. Biological significance of endogenous methylarginines that inhibit nitric oxide synthases. Leiper J, Vallance P, Cardiovasc Res 1999 43 542 548 10.1016/S0008-6363(99)00162-5 10690326 (Pubitemid 29369253)
3. Regulation of eNOS-derived superoxide by endogenous methylarginines. Druhan LJ, Forbes SP, Pope AJ, Chen CA, Zweier JL, Cardounel AJ, Biochemistry 2008 47 7256 7263 10.1021/bi702377a 18553936 (Pubitemid 351956374)
4. ADMA metabolism and clearance. Teerlink T, Vasc Med 2005 10 73 S81 10.1177/1358836X0501000111 16444872
5. Protein arginine methyltransferases and cancer. Yang Y, Bedford MT, Nat Rev Cancer 2013 13 37 50 23235912
6. Influence of citrate and EDTA anticoagulants on plasma malondialdehyde concentrations estimated by high-performance liquid chromatography. Suttnar J, Masova L, Dyr JE, J Chromatogr B Biomed Sci Appl 2001 751 193 197 10.1016/S0378-4347(00)00453-9 11232851 (Pubitemid 32146328)
7. Fast and Efficient Determination of Arginine, Symmetric Dimethylarginine, and Asymmetric Dimethylarginine in Biological Fluids by Hydrophilic-Interaction Liquid Chromatography- Electrospray Tandem Mass Spectrometry. Martens-Lobenhoffer J, Bode-Boger SM, Clin Chem 2006 52 3488 3493
8. Rapid determination of nitrite by reversed-phase high-performance liquid chromatography with fluorescence detection. Li H, Meininger CJ, Wu G, J Chromatogr B Biomed Sci Appl 2000 746 199 207 10.1016/S0378-4347(00)00328-5 11076072 (Pubitemid 30657936)
9. Expression of inducible nitric oxide synthase (NOS) in bone marrow cells of myelodysplastic syndromes. Kitagawa M, Takahashi M, Yamaguchi S, Inoue M, Ogawa S, Hirokawa K, Kamiyama R, Leukemia 1999 13 699 703 10.1038/sj.leu.2401407 10374872 (Pubitemid 29243619)
10. Plasma nitrite rather than nitrate reflects regional endothelial nitric oxide synthase activity but lacks intrinsic vasodilator action. Lauer T, Preik M, Rassaf T, Strauer BE, Deussen A, Feelisch M, Kelm M, Proc Natl Acad Sci U S A 2001 98 12814 12819 10.1073/pnas.221381098 11606734 (Pubitemid 33020027)
11. Protein methyltransferases as a target class for drug discovery. Copeland RA, Solomon ME, Richon VM, Nat Rev Drug Discov 2009 8 724 732 10.1038/nrd2974 19721445