Aortic stiffness determines diastolic blood flow reversal in the descending thoracic aorta: Potential implication for retrograde embolic stroke in hypertension

Hypertension

Volumn 62, Issue 3, 2013, Pages 542-549

  Hashimoto, Junichiro ^a   Ito, Sadayoshi ^a  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

aorta; atherosclerosis; blood flow velocity; carotid arteries; physiopathology; stroke; vascular stiffness

Indexed keywords

ADULT; AGE DISTRIBUTION; AGED; AORTA; AORTA FLOW; AORTA PRESSURE; ARTERIAL STIFFNESS; ARTICLE; AUGMENTATION INDEX; BLOOD FLOW VELOCITY; BODY MASS; CARDIOEMBOLIC STROKE; CAROTID ARTERY; CAROTID ARTERY FLOW; DESCENDING AORTA; DIASTOLIC BLOOD PRESSURE; FEMALE; HEART MUSCLE BLOOD FLOW; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; MEAN ARTERIAL PRESSURE; PRIORITY JOURNAL; PULSE PRESSURE; PULSE WAVE; RADIAL ARTERY; SYSTOLIC BLOOD PRESSURE; THORACIC AORTA; TONOMETRY; WAVEFORM;

AORTA; ATHEROSCLEROSIS; BLOOD FLOW VELOCITY; CAROTID ARTERIES; PHYSIOPATHOLOGY; STROKE; VASCULAR STIFFNESS;

ADULT; AGED; AORTA, THORACIC; BLOOD FLOW VELOCITY; BLOOD PRESSURE; FEMALE; HEMODYNAMICS; HUMANS; HYPERTENSION; INTRACRANIAL EMBOLISM; MALE; MIDDLE AGED; PULSATILE FLOW; RISK FACTORS; STROKE; VASCULAR STIFFNESS;

EID: 84883299882     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.113.01318     Document Type: Article

References (46)

1. Vlachopoulos C, Aznaouridis K, O'Rourke MF, Safar ME, Baou K, Stefanadis C. Prediction of cardiovascular events and all-cause mortality with central haemodynamics: A systematic review and meta-analysis. Eur Heart J. 2010;31:1865-1871.
2. Laurent S, Katsahian S, Fassot C, Tropeano AI, Gautier I, Laloux B, Boutouyrie P. Aortic stiffness is an independent predictor of fatal stroke in essential hypertension. Stroke. 2003;34:1203-1206.
3. Laurent S, Boutouyrie P, Asmar R, Gautier I, Laloux B, Guize L, Ducimetiere P, Benetos A. Aortic stiffness is an independent predictor of all-cause and cardiovascular mortality in hypertensive patients. Hypertension. 2001;37:1236-1241.
4. Boutouyrie P, Tropeano AI, Asmar R, Gautier I, Benetos A, Lacolley P, Laurent S. Aortic stiffness is an independent predictor of primary coronary events in hypertensive patients: A longitudinal study. Hypertension. 2002;39:10-15.
5. Blacher J, Guerin AP, Pannier B, Marchais SJ, Safar ME, London GM. Impact of aortic stiffness on survival in end-stage renal disease. Circulation. 1999;99:2434-2439.
6. Sutton-Tyrrell K, Najjar SS, Boudreau RM, Venkitachalam L, Kupelian V, Simonsick EM, Havlik R, Lakatta EG, Spurgeon H, Kritchevsky S, Pahor M, Bauer D, Newman A; Health ABC Study. Elevated aortic pulse wave velocity, a marker of arterial stiffness, predicts cardiovascular events in well-functioning older adults. Circulation. 2005;111:3384-3390.
7. Mattace-Raso FU, van der Cammen TJ, Hofman A, van Popele NM, Bos ML, Schalekamp MA, Asmar R, Reneman RS, Hoeks AP, Breteler MM, Witteman JC. Arterial stiffness and risk of coronary heart disease and stroke: The Rotterdam study. Circulation. 2006;113:657-663.
8. O'Rourke MF, Safar ME. Relationship between aortic stiffening and microvascular disease in brain and kidney: Cause and logic of therapy. Hypertension. 2005;46:200-204.
9. O'Rourke MF, Hashimoto J. Mechanical factors in arterial aging: A clinical perspective. J Am Coll Cardiol. 2007;50:1-13.
10. Safar ME. Peripheral pulse pressure, large arteries, and microvessels. Hypertension. 2004;44:121-122.
11. Henskens LH, Kroon AA, van Oostenbrugge RJ, Gronenschild EH, Fuss-Lejeune MM, Hofman PA, Lodder J, de Leeuw PW. Increased aortic pulse wave velocity is associated with silent cerebral small-vessel disease in hypertensive patients. Hypertension. 2008;52:1120-1126.
12. Hashimoto J, Aikawa T, Imai Y. Large artery stiffening as a link between cerebral lacunar infarction and renal albuminuria. Am J Hypertens. 2008;21:1304-1309.
13. Shrestha I, Takahashi T, Nomura E, Ohtsuki T, Ohshita T, Ueno H, Kohriyama T, Matsumoto M. Association between central systolic blood pressure, white matter lesions in cerebral MRI and carotid atherosclerosis. Hypertens Res. 2009;32:869-874.
14. Brandts A, van Elderen SG, Westenberg JJ, van der Grond J, van Buchem MA, Huisman MV, Kroft LJ, Tamsma JT, de Roos A. Association of aortic arch pulse wave velocity with left ventricular mass and lacunar brain infarcts in hypertensive patients: Assessment with MR imaging. Radiology. 2009;253:681-688.
15. Poels MM, Zaccai K, Verwoert GC, Vernooij MW, Hofman A, van der Lugt A, Witteman JC, Breteler MM, Mattace-Raso FU, Ikram MA. Arterial stiffness and cerebral small vessel disease: The Rotterdam Scan study. Stroke. 2012;43:2637-2642.
16. Benchimol A, Desser KB, Gartlan JL Jr. Bidirectional blood flow velocity in the cardiac chambers and great vessels studied with the Doppler ultrasonic flowmeter. Am J Med. 1972;52:467-473.
17. Otto CM. Textbook of Clinical Echocardiography. Philadelphia: Elsevier; 2004.
18. Boughner DR. Assessment of aortic insufficiency by transcutaneous Doppler ultrasound. Circulation. 1975;52:874-879.
19. Reimold SC, Maier SE, Aggarwal K, Fleischmann KE, Piwnica-Worms D, Kikinis R, Lee RT. Aortic flow velocity patterns in chronic aortic regurgitation: Implications for Doppler echocardiography. J Am Soc Echocardiogr. 1996;9:675-683.
20. Harloff A, Strecker C, Dudler P, Nussbaumer A, Frydrychowicz A, Olschewski M, Bock J, Stalder AF, Stroh AL, Weiller C, Hennig J, Markl M. Retrograde embolism from the descending aorta: Visualization by multidirectional 3D velocity mapping in cryptogenic stroke. Stroke. 2009;40:1505-1508.
21. Svedlund S, Wetterholm R, Volkmann R, Caidahl K. Retrograde blood flow in the aortic arch determined by transesophageal Doppler ultrasound. Cerebrovasc Dis. 2009;27:22-28.
22. Harloff A, Simon J, Brendecke S, Assefa D, Helbing T, Frydrychowicz A, Weber J, Olschewski M, Strecker C, Hennig J, Weiller C, Markl M. Complex plaques in the proximal descending aorta: An underestimated embolic source of stroke. Stroke. 2010;41:1145-1150.
23. Hashimoto J, Ito S. Pulse pressure amplification, arterial stiffness, and peripheral wave reflection determine pulsatile flow waveform of the femoral artery. Hypertension. 2010;56:926-933.
24. Hashimoto J, Ito S. Central pulse pressure and aortic stiffness determine renal hemodynamics: Pathophysiological implication for microalbuminuria in hypertension. Hypertension. 2011;58:839-846.
25. Omoto R, Yokote Y, Takamoto S, Kyo S, Ueda K, Asano H, Namekawa K, Kasai C, Kondo Y, Koyano A. The development of real-time two-dimensional Doppler echocardiography and its clinical significance in acquired valvular diseases. With special reference to the evaluation of valvular regurgitation. Jpn Heart J. 1984;25:325-340.
26. Weber T., Ammer M, Rammer M, Adji A, O'Rourke MF, Wassertheurer S, Rosenkranz S, Eber B. Noninvasive determination of carotid-femoral pulse wave velocity depends critically on assessment of travel distance: A comparison with invasive measurement. J Hypertens. 2009;27:1624-1630.
27. The Reference Values for Arterial Siffness' Collaboration. Determinants of pulse wave velocity in healthy people and in the presence of cardiovascular risk factors: 'establishing normal and reference values'. Eur Heart J. 2010;31:2338-2350.
28. Van Bortel LM, Laurent S, Boutouyrie P, Chowienczyk P, Cruickshank JK, De Backer T, Filipovsky J, Huybrechts S, Mattace-Raso FU, Protogerou AD, Schillaci G, Segers P, Vermeersch S, Weber T.; Artery Society; European Society of Hypertension Working Group on Vascular Structure and Function; European Network for Noninvasive Investigation of Large Arteries. Expert consensus document on the measurement of aortic stiffness in daily practice using carotid-femoral pulse wave velocity. J Hypertens. 2012;30:445-448.
29. Dujardin JP, Stone DN. Characteristic impedance of the proximal aorta determined in the time and frequency domain: A comparison. Med Biol Eng Comput. 1981;19:565-568.
30. Lucas CL, Wilcox BR, Ha B, Henry GW. Comparison of time domain algorithms for estimating aortic characteristic impedance in humans. IEEE Trans Biomed Eng. 1988;35:62-68.
31. Nichols WW, O'Rourke MF, Vlachopoulos C. McDonald's Blood Flow in Arteries: Theorertical, Experimental and Clinical Principles. London: Hodder Arnold; 2011.
32. Bland JM, Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet. 1986;1:307-310.
33. Tribouilloy C, Avinée P, Shen WF, Rey JL, Slama M, Lesbre JP. End diastolic flow velocity just beneath the aortic isthmus assessed by pulsed Doppler echocardiography: A new predictor of the aortic regurgitant fraction. Br Heart J. 1991;65:37-40.
34. Belz GG. Elastic properties and Windkessel function of the human aorta. Cardiovasc Drugs Ther. 1995;9:73-83.
35. Green D, Cheetham C, Reed C, Dembo L, O'Driscoll G. Assessment of brachial artery blood flow across the cardiac cycle: Retrograde flows during cycle ergometry. J Appl Physiol. 2002;93:361-368.
36. Bogren HG, Buonocore MH. Blood flow measurements in the aorta and major arteries with MR velocity mapping. J Magn Reson Imaging. 1994;4:119-130.
37. Miyashita H, Ikeda U, Tsuruya Y, Sekiguchi H, Shimada K, Yaginuma T. Noninvasive evaluation of the influence of aortic wave reflection on left ventricular ejection during auxotonic contraction. Heart Vessels. 1994;9:30-39.
38. Mitchell GF. Triangulating the peaks of arterial pressure. Hypertension. 2006;48:543-545.
39. O'Rourke MF. Pressure and flow waves in systemic arteries and the anatomical design of the arterial system. J Appl Physiol. 1967;23:139-149.
40. Hirata K, Yaginuma T, O'Rourke MF, Kawakami M. Age-related changes in carotid artery flow and pressure pulses: Possible implications for cerebral microvascular disease. Stroke. 2006;37:2552-2556.
41. Kronzon I, Tunick PA. Aortic atherosclerotic disease and stroke. Circulation. 2006;114:63-75.
42. Meissner I, Khandheria BK, Sheps SG, Schwartz GL, Wiebers DO, Whisnant JP, Covalt JL, Petterson TM, Christianson TJ, Agmon Y. Atherosclerosis of the aorta: Risk factor, risk marker, or innocent bystander? A prospective population-based transesophageal echocardiography study. J Am Coll Cardiol. 2004;44:1018-1024.
43. Amarenco P, Cohen A, Tzourio C, Bertrand B, Hommel M, Besson G, Chauvel C, Touboul PJ, Bousser MG. Atherosclerotic disease of the aortic arch and the risk of ischemic stroke. N Engl J Med. 1994;331:1474-1479.
44. Jones EF, Kalman JM, Calafiore P, Tonkin AM, Donnan GA. Proximal aortic atheroma. An independent risk factor for cerebral ischemia. Stroke. 1995;26:218-224.
45. Hashimoto J, Ito S. Some mechanical aspects of arterial aging: Physiological overview based on pulse wave analysis. Ther Adv Cardiovasc Dis. 2009;3:367-378.
46. Safar ME, Jankowski P. Antihypertensive therapy and de-stiffening of the arteries. Expert Opin Pharmacother. 2010;11:2625-2634.