Levodopa changes the severity of freezing in Parkinson's disease

Parkinsonism and Related Disorders

Volumn 19, Issue 10, 2013, Pages 894-896

  Fietzek, Urban M ^a   Zwosta, Jens ^a   Schroeteler, Frauke E ^a   Ziegler, Kerstin ^a   Ceballos Baumann, Andres O ^a,b  

^a Center for Parkinson's Disease and Movement Disorders   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Freezing of gait; Gait; Levodopa; Parkinson's disease

Indexed keywords

LEVODOPA; PIRIBEDIL; PRAMIPEXOLE; ROPINIROLE;

ADULT; AGED; AKINESIA; ARTICLE; CLINICAL ARTICLE; DISEASE SEVERITY; DRUG EFFICACY; FEMALE; FESTINATION; FREEZING OF GAIT; GAIT; GAIT DISORDER; HUMAN; MALE; PARKINSON DISEASE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RATING SCALE; SCORING SYSTEM; TREATMENT OUTCOME;

FREEZING OF GAIT; GAIT; LEVODOPA; PARKINSON'S DISEASE;

ADULT; AGED; ANTIPARKINSON AGENTS; BIOMECHANICAL PHENOMENA; COGNITION; DISEASE PROGRESSION; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GAIT; HUMANS; LEVODOPA; MALE; NEUROPSYCHOLOGICAL TESTS; PARKINSON DISEASE;

EID: 84883276973     PISSN: 13538020     EISSN: 18735126     Source Type: Journal    
DOI: 10.1016/j.parkreldis.2013.04.004     Document Type: Article

References (17)

1. Giladi N., Nieuwboer A. Understanding and treating freezing of gait in parkinsonism, proposed working definition, and setting the stage. Mov Disord 2008, 23(Suppl. 2):S423-S425.
2. Bartels A.L., Balash Y., Gurevich T., Schaafsma J.D., Hausdorff J.M., Giladi N. Relationship between freezing of gait (FOG) and other features of Parkinson's: FOG is not correlated with bradykinesia. JClin Neurosci 2003, 10(5):584-588.
3. Moore O., Peretz C., Giladi N. Freezing of gait affects quality of life of peoples with Parkinson's disease beyond its relationships with mobility and gait. Mov Disord 2007 Nov 15, 22(15):2192-2195.
4. Snijders A.H., Nijkrake M.J., Bakker M., Munneke M., Wind C., Bloem B.R. Clinimetrics of freezing of gait. Mov Disord 2008, 23(Suppl. 2):S468-S474.
5. Ziegler K., Schroeteler F., Ceballos-Baumann A.O., Fietzek U.M. Anew rating instrument to assess festination and freezing gait in Parkinsonian patients. Mov Disord 2010 Juni 15, 25(8):1012-1018.
6. Schaafsma J.D., Giladi N., Balash Y., Bartels A.L., Gurevich T., Hausdorff J.M. Gait dynamics in Parkinson's disease: relationship to Parkinsonian features, falls and response to levodopa. JNeurol Sci 2003, 212(1-2):47-53.
7. Ambani L.M., Van Woert M.H. Start hesitation-a side effect of long-term levodopa therapy. NEngl J Med 1973 Mai 24, 288(21):1113-1115.
8. Narabayashi H. The neural mechanisms and progressive nature of symptoms of Parkinson's disease-based on clinical, neurophysiological and morphological studies. JNeural Transm Park Dis Dement Sect 1995, 10(1):63-75.
9. Rascol O., Brooks D.J., Korczyn A.D., De Deyn P.P., Clarke C.E., Lang A.E. Afive-year study of the incidence of dyskinesia in patients with early Parkinson's disease who were treated with ropinirole or levodopa. 056 Study Group. NEngl J Med 2000 Mai 18, 342(20):1484-1491.
10. Holloway R.G., Shoulson I., Fahn S., Kieburtz K., Lang A., Marek K., et al. Pramipexole vs levodopa as initial treatment for Parkinson disease: a 4-year randomized controlled trial. Arch Neurol 2004 Juli, 61(7):1044-1053.
11. Espay A.J., Fasano A., Van Nuenen B.F.L., Payne M.M., Snijders A.H., Bloem B.R. "On" state freezing of gait in Parkinson disease: a paradoxical levodopa-induced complication. Neurology 2012 Feb 14, 78(7):454-457.
12. Giladi N., Shabtai H., Simon E.S., Biran S., Tal J., Korczyn A.D. Construction of freezing of gait questionnaire for patients with Parkinsonism. Parkinsonism Relat Disord 2000, 6(3):165-170.
13. Giladi N. Medical treatment of freezing of gait. Mov Disord 2008, 23(Suppl. 2):S482-S488.
14. Stern G.M., Lander C.M., Lees A.J. Akinetic freezing and trick movements in Parkinson's disease. JNeural Transm Suppl 1980, 16:137-141.
15. Giladi N., Tal J., Azulay T., Rascol O., Brooks D.J., Melamed E., et al. Validation of the freezing of gait questionnaire in patients with Parkinson's disease. Mov Disord 2009 Apr 15, 24(5):655-661.
16. Shine J.M., Moore S.T., Bolitho S.J., Morris T.R., Dilda V., Naismith S.L., et al. Assessing the utility of Freezing of Gait Questionnaires in Parkinson's Disease. Parkinsonism Relat Disord 2012 Jan, 18(1):25-29.
17. Iansek R., Huxham F., McGinley J. The sequence effect and gait festination in Parkinson disease: contributors to freezing of gait?. Mov Disord 2006, 21(9):1419-1424.