Chronic primary central nervous system histoplasmosis in a healthy child with intermittent neurological manifestations

Pediatric Infectious Disease Journal

Volumn 32, Issue 7, 2013, Pages 794-796

  Schuster, Jennifer E ^a   Wushensky, Curtis A ^a   Di Pentima, M Cecilia ^a  

^a VANDERBILT UNIVERSITY   (United States)

Author keywords

Chronic infection; Demyelinating disease; Fungal meningitis; Histoplasma capsulatum

Indexed keywords

AMPHOTERICIN B LIPID COMPLEX; C REACTIVE PROTEIN; HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY; PREDNISOLONE;

ACUTE DISSEMINATED ENCEPHALOMYELITIS; ANTIBODY TITER; ARTICLE; BLOOD CELL COUNT; BORRELIA BURGDORFERI; CASE REPORT; CENTRAL NERVOUS SYSTEM INFECTION; CEREBROSPINAL FLUID CULTURE; CHILD; COMPUTER ASSISTED TOMOGRAPHY; DEMYELINATING DISEASE; DIFFERENTIAL DIAGNOSIS; FUNGAL MENINGITIS; HEADACHE; HISTOPLASMA CAPSULATUM; HISTOPLASMOSIS; HUMAN; LIVER FUNCTION TEST; LUMBAR PUNCTURE; MALE; MEDICAL ASSESSMENT; MULTIPLE SCLEROSIS; NEUROIMAGING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRESCHOOL CHILD; PRIORITY JOURNAL; SARCOIDOSIS; SLURRED SPEECH; SOMNOLENCE; THORAX RADIOGRAPHY; VOMITING;

BRAIN; CHILD; CHRONIC DISEASE; HISTOPLASMA; HISTOPLASMOSIS; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MENINGITIS, FUNGAL; RECURRENCE;

EID: 84883246273     PISSN: 08913668     EISSN: 15320987     Source Type: Journal    
DOI: 10.1097/INF.0b013e31828d293e     Document Type: Article

References (11)

1. Christie A, Peterson JC. Pulmonary Calcification in Negative Reactors to Tuberculin. Am J Public Health Nations Health. 1945;35:1131-1147.
2. Wheat LJ, Batteiger BE, Sathapatayavongs B. Histoplasma capsulatum infections of the central nervous system. A clinical review. Medicine (Baltimore). 1990;69:244-260.
3. Rubin H, Furcolow ML, Yates JL, et al. The course and prognosis of histoplasmosis. Am J Med. 1959;27:278-288.
4. Rivera IV, Curless RG, Indacochea FJ, et al. Chronic progressive CNS histoplasmosis presenting in childhood: response to fluconazole therapy. Pediatr Neurol. 1992;8:151-153.
5. Thompson GR 3rd, LaValle CE 3rd, Everett ED. Unusual manifestations of histoplasmosis. Diagn Microbiol Infect Dis. 2004;50:33-41.
6. Schestatsky P, Chedid MF, Amaral OB, et al. Isolated central nervous system histoplasmosis in immunocompetent hosts: a series of 11 cases. Scand J Infect Dis. 2006;38:43-48.
7. Threlkeld ZD, Broughton R, Khan GQ, et al. Isolated Histoplasma capsulatum meningoencephalitis in an immunocompetent child. J Child Neurol. 2012;27:532-535.
8. McKinsey DS, Spiegel RA, Hutwagner L, et al. Prospective study of histoplasmosis in patients infected with human immunodeficiency virus: incidence, risk factors, and pathophysiology. Clin Infect Dis. 1997;24:1195-1203.
9. Wheat LJ, Kohler RB, Tewari RP, et al. Significance of Histoplasma antigen in the cerebrospinal fluid of patients with meningitis. Arch Intern Med. 1989;149:302-304.
10. Wheat J, French M, Batteiger B, et al. Cerebrospinal fluid Histoplasma antibodies in central nervous system histoplasmosis. Arch Intern Med. 1985;145:1237-1240.
11. Wheat LJ, Musial CE, Jenny-Avital E. Diagnosis and management of central nervous system histoplasmosis. Clin Infect Dis. 2005;40: 844-852.