-
1
-
-
55949101031
-
Tyrosine kinase inhibitors: Can promising new therapy associated with cardiac toxicity strengthen the concept of teamwork?
-
Lenihan DJ. Tyrosine kinase inhibitors: Can promising new therapy associated with cardiac toxicity strengthen the concept of teamwork? J Clin Oncol 2008;26:5154-5155.
-
(2008)
J Clin Oncol
, vol.26
, pp. 5154-5155
-
-
Lenihan, D.J.1
-
2
-
-
77955865478
-
Why do kinase inhibitors cause cardiotoxicity and what can be done about it?
-
Cheng H, Force T. Why do kinase inhibitors cause cardiotoxicity and what can be done about it? Prog Cardiovasc Dis 2010;53:114-120.
-
(2010)
Prog Cardiovasc Dis
, vol.53
, pp. 114-120
-
-
Cheng, H.1
Force, T.2
-
3
-
-
50949132320
-
Mechanisms of cardiomyopathyassociatedwithtyrosinekinaseinhibitor cancer therapeutics
-
Chen MH, Kerkela R, Force T. Mechanisms of cardiomyopathyassociatedwithtyrosinekinaseinhibitor cancer therapeutics. Circulation 2008;118:84-95.
-
(2008)
Circulation
, vol.118
, pp. 84-95
-
-
Chen, M.H.1
Kerkela, R.2
Force, T.3
-
4
-
-
65549132325
-
Cardiac dysfunction induced by novel targeted anticancer therapy: An emerging issue
-
Chen MH. Cardiac dysfunction induced by novel targeted anticancer therapy: An emerging issue. Curr Cardiol Rep 2009;11:167-174.
-
(2009)
Curr Cardiol Rep
, vol.11
, pp. 167-174
-
-
Chen, M.H.1
-
5
-
-
34548276036
-
Molecularly targeted oncology therapeutics and prolongation of the QT interval
-
Strevel EL, Ing DJ, Siu LL. Molecularly targeted oncology therapeutics and prolongation of the QT interval. J Clin Oncol 2007;25:3362-3371.
-
(2007)
J Clin Oncol
, vol.25
, pp. 3362-3371
-
-
Strevel, E.L.1
Ing, D.J.2
Siu, L.L.3
-
6
-
-
55549144710
-
Therapy insight: Management of cardiovascular disease in patients with cancer and cardiac complications of cancer therapy
-
Khakoo AY, Yeh ETH. Therapy insight: Management of cardiovascular disease in patients with cancer and cardiac complications of cancer therapy. Nat Clin Pract Oncol 2008;5:655-667.
-
(2008)
Nat Clin Pract Oncol
, vol.5
, pp. 655-667
-
-
Khakoo, A.Y.1
Yeh, E.T.H.2
-
7
-
-
77949890945
-
Pazopanib in locally advanced or metastatic renal cell carcinoma: Results of a randomized phase III trial
-
Sternberg CN, Davis ID, Mardiak J et al. Pazopanib in locally advanced or metastatic renal cell carcinoma: Results of a randomized phase III trial. J Clin Oncol 2010;28:1061-1068.
-
(2010)
J Clin Oncol
, vol.28
, pp. 1061-1068
-
-
Sternberg, C.N.1
Davis, I.D.2
Mardiak, J.3
-
8
-
-
84862125953
-
Clinical cardiac safety profile of nilotinib
-
Kim TD, le Coutre P, SchwarzMet al. Clinical cardiac safety profile of nilotinib. Haematologica 2012; 97:883-889.
-
(2012)
Haematologica
, vol.97
, pp. 883-889
-
-
Kim, T.D.1
le Coutre, P.2
Schwarz, M.3
-
9
-
-
79960210309
-
The importance of clinical grading of heart failure and other cardiac toxicities during chemotherapy: Updating the common terminology criteria for clinical trial reporting
-
Hossain A, Chen A, Ivy P et al. The importance of clinical grading of heart failure and other cardiac toxicities during chemotherapy: Updating the common terminology criteria for clinical trial reporting. Heart Fail Clin 2011;7:373-384.
-
(2011)
Heart Fail Clin
, vol.7
, pp. 373-384
-
-
Hossain, A.1
Chen, A.2
Ivy, P.3
-
10
-
-
77952038495
-
Initial assessment, surveillance, and management of blood pressure in patients receiving vascular endothelial growth factor signaling pathway inhibitors
-
Maitland ML, Bakris GL, Black HR et al. Initial assessment, surveillance, and management of blood pressure in patients receiving vascular endothelial growth factor signaling pathway inhibitors. J Natl Cancer Inst 2010;102:596-604.
-
(2010)
J Natl Cancer Inst
, vol.102
, pp. 596-604
-
-
Maitland, M.L.1
Bakris, G.L.2
Black, H.R.3
-
11
-
-
3242881591
-
-
National Cancer Institute. Available at: Accessed May 13, 2013
-
National Cancer Institute. Common Terminology Criteria for Adverse Events v 3.0. Available at: http://ctep.cancer.gov/protocolDevelopment/ electronic_applications/docs/ctcaev3.pdf. Accessed May 13, 2013.
-
Common Terminology Criteria for Adverse Events v 3.0
-
-
-
12
-
-
70350238222
-
-
National Cancer Institute. Available at: Accessed May 13, 2013
-
National Cancer Institute. Common Terminology Criteria for Adverse Events v 4.0. Available at: http://evs.nci.nih.gov/ftp1/CTCAE/CTCAE_ 4.03_2010-06-14_QuickReference_8.5x11.pdf. Accessed May 13, 2013.
-
Common Terminology Criteria for Adverse Events v 4.0
-
-
-
15
-
-
77951668218
-
Statistical characterization of QT prolongation
-
Schall R, Ring A. Statistical characterization of QT prolongation. J Biopharm Stat 2010;20:543-562.
-
(2010)
J Biopharm Stat
, vol.20
, pp. 543-562
-
-
Schall, R.1
Ring, A.2
-
16
-
-
84883237556
-
-
Wilmington, DE: AstraZeneca Pharmaceuticals LP; Available at
-
Caprelsa [package insert]. Wilmington, DE: AstraZeneca Pharmaceuticals LP; 2012. Available at: http://www.astrazeneca-us.com.
-
(2012)
Caprelsa [package insert]
-
-
-
17
-
-
41549098043
-
-
New York, NY: Pfizer Inc; Available at
-
Sutent [package insert]. New York, NY: Pfizer Inc; 2012. Available at: http://www.pfizer.com.
-
(2012)
Sutent [package insert]
-
-
-
18
-
-
84883245633
-
-
East Hanover, NJ: Novartis Pharmaceuticals Corporation; Available at
-
Tasigna [package insert]. East Hanover, NJ: Novartis Pharmaceuticals Corporation; 2012. Available at: http://www.novartis.com.
-
(2012)
Tasigna [package insert]
-
-
-
19
-
-
84883257968
-
-
Research Triangle Park, NC: GlaxoSmithKline; Available at
-
Tykerb [package insert]. Research Triangle Park, NC: GlaxoSmithKline; 2012. Available at: http://www.gsk.com/.
-
(2012)
Tykerb [package insert]
-
-
-
20
-
-
84883207550
-
-
Research Triangle Park, NC: GlaxoSmithKline; Available at
-
Votrient [package insert]. Research Triangle Park, NC: GlaxoSmithKline; 2012. Available at: http://www.gsk.com/.
-
(2012)
Votrient [package insert]
-
-
-
21
-
-
79952281292
-
-
Wayne, NJ: Bayer HealthCare Pharmaceuticals Inc.; Available at
-
Nexavar [package insert]. Wayne, NJ: Bayer HealthCare Pharmaceuticals Inc.; 2011. Available at: http://www.bayer.com.
-
(2011)
Nexavar [package insert]
-
-
-
22
-
-
84883229213
-
-
South San Francisco, CA: Exelixis, Inc.; Available at
-
Cometriq [package insert]. South San Francisco, CA: Exelixis, Inc.; 2012. Available at: http:// www.exelixis.com/.
-
(2012)
Cometriq [package insert]
-
-
-
23
-
-
84883251611
-
-
South San Francisco, CA: Genentech, Inc.; Available at
-
Avastin [package insert]. South San Francisco, CA: Genentech, Inc.; 2012. Available at: http:// www.gene.com/.
-
(2012)
Avastin [package insert]
-
-
-
24
-
-
79959698017
-
-
South San Francisco, CA: Genentech, Inc.; Available at
-
Herceptin [package insert]. South San Francisco, CA: Genentech, Inc.; 2010. Available at: http://www.gene.com/.
-
(2010)
Herceptin [package insert]
-
-
-
25
-
-
80053539103
-
Adjuvant trastuzumab in HER2-positive breast cancer
-
Slamon D, Eiermann W, Robert N et al. Adjuvant trastuzumab in HER2-positive breast cancer. N Engl J Med 2011;365:1273-1283.
-
(2011)
N Engl J Med
, vol.365
, pp. 1273-1283
-
-
Slamon, D.1
Eiermann, W.2
Robert, N.3
-
26
-
-
84858848994
-
Meta-analysis of randomized controlled trials for the incidence and risk of treatment-related mortality in patients with cancer treated with vascular endothelial growth factor tyrosine kinase inhibitors
-
Schutz FA, Je Y, Richards CJ et al. Meta-analysis of randomized controlled trials for the incidence and risk of treatment-related mortality in patients with cancer treated with vascular endothelial growth factor tyrosine kinase inhibitors. J Clin Oncol 2012;30:871-877.
-
(2012)
J Clin Oncol
, vol.30
, pp. 871-877
-
-
Schutz, F.A.1
Je, Y.2
Richards, C.J.3
-
27
-
-
0032907687
-
Vascular endothelial growth factor (VEGF) and its receptors
-
Neufeld G, Cohen T, Gengrinovitch S et al. Vascular endothelial growth factor (VEGF) and its receptors. FASEB J 1999;13:9-22.
-
(1999)
FASEB J
, vol.13
, pp. 9-22
-
-
Neufeld, G.1
Cohen, T.2
Gengrinovitch, S.3
-
28
-
-
43049085201
-
Blood pressure rise following angiogenesis inhibition by bevacizumab. A crucial role for microcirculation
-
Mourad JJ, des Guetz G, DebbabiHet al. Blood pressure rise following angiogenesis inhibition by bevacizumab. A crucial role for microcirculation. Ann Oncol 2008;19:927-934.
-
(2008)
Ann Oncol
, vol.19
, pp. 927-934
-
-
Mourad, J.J.1
des Guetz, G.2
Debbabi, H.3
-
29
-
-
50349101200
-
Hypertension and rarefaction during treatment with telatinib, a small molecule angiogenesis inhibitor
-
Steeghs N, Gelderblom H, Roodt JO et al. Hypertension and rarefaction during treatment with telatinib, a small molecule angiogenesis inhibitor. Clin Cancer Res 2008;14:3470-3476.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 3470-3476
-
-
Steeghs, N.1
Gelderblom, H.2
Roodt, J.O.3
-
30
-
-
70349249625
-
Vascular endothelial growth factor receptor 2 controls blood pressure by regulating nitric oxide synthase expression
-
Facemire CS, Nixon AB, Griffiths R et al. Vascular endothelial growth factor receptor 2 controls blood pressure by regulating nitric oxide synthase expression. Hypertension 2009;54:652-658.
-
(2009)
Hypertension
, vol.54
, pp. 652-658
-
-
Facemire, C.S.1
Nixon, A.B.2
Griffiths, R.3
-
31
-
-
33645449812
-
Mechanisms of hypertension associated with BAY 43-9006
-
Veronese ML, Mosenkis A, Flaherty KT et al. Mechanisms of hypertension associated with BAY 43-9006. J Clin Oncol 2006;24:1363-1369.
-
(2006)
J Clin Oncol
, vol.24
, pp. 1363-1369
-
-
Veronese, M.L.1
Mosenkis, A.2
Flaherty, K.T.3
-
32
-
-
74049092701
-
Sunitinib-induced cardiotoxicity is mediated by offtarget inhibition of AMP-activated protein kinase
-
Kerkela R, Woulfe KC, Durand J-B et al. Sunitinib-induced cardiotoxicity is mediated by offtarget inhibition of AMP-activated protein kinase. Clin Transl Sci 2009;2:15-25.
-
(2009)
Clin Transl Sci
, vol.2
, pp. 15-25
-
-
Kerkela, R.1
Woulfe, K.C.2
Durand, J.-B.3
-
33
-
-
34547615709
-
2007 Guidelines for the management of arterial hypertension: The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC)
-
Mancia G, De Backer G, Dominiczak A et al. 2007 Guidelines for the management of arterial hypertension: The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). Eur Heart J 2007;28:1462-1536.
-
(2007)
Eur Heart J
, vol.28
, pp. 1462-1536
-
-
Mancia, G.1
De Backer, G.2
Dominiczak, A.3
-
34
-
-
51249084565
-
Cardiotoxicity of the new cancer therapeutics-mechanisms of, and approaches to, the problem
-
Force T, Kerkela R. Cardiotoxicity of the new cancer therapeutics-mechanisms of, and approaches to, the problem. Drug Discov Today 2008; 13:778-784.
-
(2008)
Drug Discov Today
, vol.13
, pp. 778-784
-
-
Force, T.1
Kerkela, R.2
-
35
-
-
33746845181
-
Cardiotoxicity of the cancer therapeutic agent imatinib mesylate
-
Kerkela R, Grazette L, YacobiRet al. Cardiotoxicity of the cancer therapeutic agent imatinib mesylate. Nat Med 2006;12:908-916.
-
(2006)
Nat Med
, vol.12
, pp. 908-916
-
-
Kerkela, R.1
Grazette, L.2
Yacobi, R.3
-
36
-
-
36849023013
-
Cardiotoxicity associated with tyrosine kinase inhibitor sunitinib
-
Chu TF, Rupnick MA, Kerkela R et al. Cardiotoxicity associated with tyrosine kinase inhibitor sunitinib. Lancet 2007;370:2011-2019.
-
(2007)
Lancet
, vol.370
, pp. 2011-2019
-
-
Chu, T.F.1
Rupnick, M.A.2
Kerkela, R.3
-
37
-
-
65549145093
-
2009 focused update incorporated into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults
-
A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines: Developed in collaboration with the International Society for Heart and Lung Transplantation
-
Hunt SA, Abraham WT, ChinMHet al. 2009 focused update incorporated into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults: A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines: Developed in collaboration with the International Society for Heart and Lung Transplantation. Circulation 2009;119:e391-e479.
-
(2009)
Circulation
, vol.119
-
-
Hunt, S.A.1
Abraham, W.T.2
Chin, M.H.3
-
38
-
-
33845206791
-
Protective effects of carvedilol against anthracycline-induced cardiomyopathy
-
Kalay N, Basar E, Ozdogru I et al. Protective effects of carvedilol against anthracycline-induced cardiomyopathy. J Am Coll Cardiol 2006;48:2258-2262.
-
(2006)
J Am Coll Cardiol
, vol.48
, pp. 2258-2262
-
-
Kalay, N.1
Basar, E.2
Ozdogru, I.3
-
39
-
-
73549087024
-
Anthracycline-induced cardiomyopathy: Clinical relevanceandresponse to pharmacologic therapy
-
Cardinale D, Colombo A, Lamantia G et al. Anthracycline-induced cardiomyopathy: Clinical relevanceandresponse to pharmacologic therapy. JAm Coll Cardiol 2010;55:213-220.
-
(2010)
JAm Coll Cardiol
, vol.55
, pp. 213-220
-
-
Cardinale, D.1
Colombo, A.2
Lamantia, G.3
-
40
-
-
0033922894
-
Betablockade in adriamycin-induced cardiomyopathy
-
Noori A, Lindenfeld J, Wolfel E et al. Betablockade in adriamycin-induced cardiomyopathy. J Card Fail 2000;6:115-119.
-
(2000)
J Card Fail
, vol.6
, pp. 115-119
-
-
Noori, A.1
Lindenfeld, J.2
Wolfel, E.3
-
42
-
-
77955936651
-
Prolonged QTc interval in cancer therapeutic drug development: Defining arrhythmic risk in malignancy
-
Brell JM. Prolonged QTc interval in cancer therapeutic drug development: Defining arrhythmic risk in malignancy. Prog Cardiovasc Dis 2010;53: 164-172.
-
(2010)
Prog Cardiovasc Dis
, vol.53
, pp. 164-172
-
-
Brell, J.M.1
-
43
-
-
0036847942
-
Cardiac repolarization: Current knowledge, critical gaps, and new approaches to drug development and patient management
-
Anderson ME, Al-Khatib SM, Roden DM et al. Cardiac repolarization: Current knowledge, critical gaps, and new approaches to drug development and patient management. Am Heart J 2002;144: 769-781.
-
(2002)
Am Heart J
, vol.144
, pp. 769-781
-
-
Anderson, M.E.1
Al-Khatib, S.M.2
Roden, D.M.3
-
44
-
-
0242494266
-
What clinicians should know about the QT interval
-
Al-Khatib SM, Allen LaPointe NM, Kramer JM et al. What clinicians should know about the QT interval. JAMA 2003;289:2120-2127.
-
(2003)
JAMA
, vol.289
, pp. 2120-2127
-
-
Al-Khatib, S.M.1
Allen LaPointe, N.M.2
Kramer, J.M.3
-
45
-
-
0001864581
-
The duration of the electrical systole (Q-T) in acute rheumatic carditis in children
-
Taran LM, Szilagyi N. The duration of the electrical systole (Q-T) in acute rheumatic carditis in children. AmHeart J 1947;33:14-26.
-
(1947)
AmHeart J
, vol.33
, pp. 14-26
-
-
Taran, L.M.1
Szilagyi, N.2
-
46
-
-
1542786569
-
The duration of systole in an electrocardiogram in normal humans and in patients with heart disease
-
1920
-
Fridericia LS. The duration of systole in an electrocardiogram in normal humans and in patients with heart disease. 1920. Ann Noninvasive Electrocardiol 2003;8:343-351.
-
(2003)
Ann Noninvasive Electrocardiol
, vol.8
, pp. 343-351
-
-
Fridericia, L.S.1
-
47
-
-
0026722151
-
An improved method for adjusting the QT interval for heart rate (the Framingham Heart Study)
-
Sagie A, Larson MG, Goldberg RJ et al. An improved method for adjusting the QT interval for heart rate (the Framingham Heart Study). AmJ Cardiol 1992;70:797-801.
-
(1992)
AmJ Cardiol
, vol.70
, pp. 797-801
-
-
Sagie, A.1
Larson, M.G.2
Goldberg, R.J.3
-
48
-
-
0038804165
-
Variability of heart rate correction methods for theQTinterval
-
Desai M, Li L, Desta Z et al. Variability of heart rate correction methods for theQTinterval. Br J Clin Pharmacol 2003;55:511-517.
-
(2003)
Br J Clin Pharmacol
, vol.55
, pp. 511-517
-
-
Desai, M.1
Li, L.2
Desta, Z.3
-
50
-
-
7544238485
-
Practice standards for electrocardiographic monitoring in hospital settings
-
An American Heart Association scientific statement from the Councils on Cardiovascular Nursing, Clinical Cardiology, and Cardiovascular Disease in the Young: Endorsed by the International Society of Computerized Electrocardiology and the American Association of Critical-Care Nurses
-
Drew BJ, Califf RM, Funk M et al. Practice standards for electrocardiographic monitoring in hospital settings: An American Heart Association scientific statement from the Councils on Cardiovascular Nursing, Clinical Cardiology, and Cardiovascular Disease in the Young: Endorsed by the International Society ofComputerizedElectrocardiology and the American Association of Critical-Care Nurses Circulation 2004;110:2721-2746.
-
(2004)
Circulation
, vol.110
, pp. 2721-2746
-
-
Drew, B.J.1
Califf, R.M.2
Funk, M.3
-
51
-
-
84883234910
-
-
U.S. Department of Health and Human Services. Available at: Accessed May 13, 2013
-
U.S. Department of Health and Human Services. Votrient (pazopanib) Supplement Approval Release REMS Requirement. Available at: http:// www.accessdata.fda.gov/drugsatfda_docs/appletter/ 2011/022465s006ltr.pdf. AccessedMay13, 2013.
-
Votrient (pazopanib) Supplement Approval Release REMS Requirement
-
-
-
52
-
-
84883254203
-
Risk Evaluation and Mitigation Strategy (REMS)
-
U.S. Food and Drug Administration. Available at: Accessed May13,2013
-
U.S. Food and Drug Administration. Risk Evaluation and Mitigation Strategy (REMS). Tasigna (nilotinib). Available at: http://www.fda.gov/downloads/ Drugs/DrugSafety/PostmarketDrugSafetyInformation forPatientsandProviders/UCM217737.pdf. Accessed May13,2013.
-
Tasigna (nilotinib)
-
-
-
53
-
-
84883234910
-
-
U.S. Department of Health andHumanServices. Available at: AccessedMay13,2013
-
U.S. Department of Health andHumanServices. Sutent (sunitinib) Supplement Approval Release REMS Requirement. Available at: http://www. accessdata.fda.gov/drugsatfda_docs/appletter/2011/ 021938s013, s017, s018ltr.pdf.AccessedMay13,2013.
-
Sutent (sunitinib) Supplement Approval Release REMS Requirement
-
-
-
54
-
-
84855608847
-
-
U.S. Food and Drug Administration. Available at: Accessed December6,2012
-
U.S. Food and Drug Administration. Caprelsa (vandetanib) Risk Evaluation and Mitigation Strategy (REMS). Available at: http://www.fda.gov/downloads/ Drugs/DrugSafety/PostmarketDrugSafetyInformation forPatientsandProviders/UCM253441.pdf. Accessed December6,2012.
-
Caprelsa (vandetanib) Risk Evaluation and Mitigation Strategy (REMS)
-
-
-
56
-
-
84883237215
-
-
CredibleMeds. Available at: Accessed May 13, 2013
-
CredibleMeds. Clinically Important Drug Interactions. Available at: http://www.azcert.org/ medical-pros/druginteractions.cfm. Accessed May 13, 2013.
-
Clinically Important Drug Interactions
-
-
-
57
-
-
0033832384
-
Hypokalemia-induced long QT syndrome with an underlying novel missense mutation in S4-S5 linker of KCNQ1
-
Kubota T, Shimizu W, Kamakura S et al. Hypokalemia-induced long QT syndrome with an underlying novel missense mutation in S4-S5 linker of KCNQ1. J Cardiovasc Electrophysiol 2000;11:1048-1054.
-
(2000)
J Cardiovasc Electrophysiol
, vol.11
, pp. 1048-1054
-
-
Kubota, T.1
Shimizu, W.2
Kamakura, S.3
-
58
-
-
0026601476
-
Torsade de pointes and long QT syndrome following major blood transfusion
-
Kulkarni P, Bhattacharya S, Petros AJ. Torsade de pointes and long QT syndrome following major blood transfusion. Anaesthesia 1992;47:125-127.
-
(1992)
Anaesthesia
, vol.47
, pp. 125-127
-
-
Kulkarni, P.1
Bhattacharya, S.2
Petros, A.J.3
|