Genetic selection for constitutively trimerized human hsf1 mutants identifies a role for coiled-coil motifs in DNA binding

G3: Genes, Genomes, Genetics

Volumn 3, Issue 8, 2013, Pages 1315-1324

  Neef, Daniel W ^a   Jaeger, Alex M ^a   Thiele, Dennis J ^a  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cell stress; Chaperones; Chromatin; HSF1; Protein; Remodeling

Indexed keywords

DNA; DNA BINDING PROTEIN; HEAT SHOCK PROTEIN 27; HEAT SHOCK PROTEIN 70; HEAT SHOCK TRANSCRIPTION FACTOR; HEAT SHOCK TRANSCRIPTION FACTOR 1; INTERLEUKIN 6; LEUCINE ZIPPER PROTEIN; TRANSCRIPTION FACTOR;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; CELL STRESS; CHEMISTRY; CHROMATIN; CHROMATIN ASSEMBLY AND DISASSEMBLY; CONTROLLED STUDY; DNA BINDING; GENE LOCUS; GENETIC SCREENING; GENETIC SELECTION; GENETICS; HSF1; HUMAN; IMMUNOBLOTTING; IN VIVO STUDY; METABOLISM; MOLECULAR GENETICS; MUTAGENESIS; MUTANT; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; NUCLEOTIDE MOTIF; PHYSIOLOGICAL STRESS; PROMOTER REGION; PROTEIN BINDING; PROTEIN CHAPERONES; PROTEIN MODIFICATION; PROTEIN MOTIF; PROTEIN MULTIMERIZATION; REGULATORY MECHANISM; SACCHAROMYCES CEREVISIAE; STRESS; TRIMERIZATION; YEAST;

CELL STRESS; CHROMATIN REMODELING; HSF1; PROTEIN CHAPERONES;

AMINO ACID SEQUENCE; ANIMALS; CHROMATIN; DNA; DNA-BINDING PROTEINS; HSP27 HEAT-SHOCK PROTEINS; HSP70 HEAT-SHOCK PROTEINS; HUMANS; INTERLEUKIN-6; LEUCINE ZIPPERS; MOLECULAR SEQUENCE DATA; MUTAGENESIS; NUCLEOTIDE MOTIFS; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PROTEIN MULTIMERIZATION; SACCHAROMYCES CEREVISIAE; SELECTION, GENETIC; STRESS, PHYSIOLOGICAL; TRANSCRIPTION FACTORS;

EID: 84883234864     PISSN: None     EISSN: 21601836     Source Type: Journal    
DOI: 10.1534/g3.113.006692     Document Type: Article

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