Asp residues of the Glu-Glu-Asp-Asp pore filter contribute to ion permeation and selectivity of the Cav3.2 T-type channel

Cell Calcium

Volumn 54, Issue 3, 2013, Pages 226-235

  Park, Hyun Jee ^a   Park, So Jung ^a   Ahn, Eun Joo ^a   Lee, So Young ^a   Seo, Haengsoo ^a   Lee, Jung Ha ^a  

^a Sogang University   (South Korea)

Author keywords

Permeation and selectivity; Proton block; Voltage clamping

Indexed keywords

ASPARTIC ACID; BARIUM; CADMIUM; CALCIUM; CALCIUM CHANNEL CAV3.2; CALCIUM CHANNEL T TYPE; GLUTAMIC ACID; UNCLASSIFIED DRUG; VOLTAGE GATED CALCIUM CHANNEL;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BIOPHYSICS; CHANNEL GATING; CONTROLLED STUDY; ELECTRIC POTENTIAL; ELECTROPHYSIOLOGY; FEMALE; HUMAN; HUMAN CELL; ION PERMEABILITY; NONHUMAN; NUCLEOTIDE SEQUENCE; OOCYTE; PH; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; VOLTAGE CLAMP; XENOPUS;

CA(V)3.2 T-TYPE CHANNEL; CD(2+) BLOCKING SENSITIVITY; PERMEATION AND SELECTIVITY; PROTON BLOCK; VOLTAGE CLAMPING;

AMINO ACID SEQUENCE; ANIMALS; ASPARTIC ACID; BARIUM; CADMIUM; CALCIUM; CALCIUM CHANNELS, T-TYPE; FEMALE; HUMANS; HYDROGEN-ION CONCENTRATION; MUTAGENESIS; OLIGOPEPTIDES; OOCYTES; PATCH-CLAMP TECHNIQUES; PROTEIN ISOFORMS; XENOPUS;

EID: 84883227056     PISSN: 01434160     EISSN: 15321991     Source Type: Journal    
DOI: 10.1016/j.ceca.2013.06.006     Document Type: Article

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