-
1
-
-
77949673913
-
The design of phase II clinical trials testing cancer therapeutics: Consensus recommendations from the clinical trial design task force of the National Cancer Institute Investigational Drug Steering Committee
-
Seymour L, Ivy SP, Sargent D et al. The design of phase II clinical trials testing cancer therapeutics: Consensus recommendations from the clinical trial design task force of the National Cancer Institute Investigational Drug Steering Committee. Clin Cancer Res 2010;16:1764-1769.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 1764-1769
-
-
Seymour, L.1
Ivy, S.P.2
Sargent, D.3
-
2
-
-
77954629858
-
The role of the U.S. Food and Drug Administration review process: Clinical trial endpoints in oncology
-
McKee AE, Farrell AT, Pazdur R et al. The role of the U.S. Food and Drug Administration review process: Clinical trial endpoints in oncology. The Oncologist 2010;15(suppl 1):13-18.
-
(2010)
The Oncologist
, vol.15
, Issue.SUPPL. 1
, pp. 13-18
-
-
McKee, A.E.1
Farrell, A.T.2
Pazdur, R.3
-
3
-
-
79955445696
-
Accelerated approval of oncology products: The Food and Drug Administration experience
-
Johnson JR, Ning YM, Farrell A et al. Accelerated approval of oncology products: The Food and Drug Administration experience. J Natl Cancer Inst 2011; 103:636-644.
-
(2011)
J Natl Cancer Inst
, vol.103
, pp. 636-644
-
-
Johnson, J.R.1
Ning, Y.M.2
Farrell, A.3
-
4
-
-
11444251764
-
Results of the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial after completion of 5 years' adjuvant treatment for breast cancer
-
Howell A, Cuzick J, Baum M et al. Results of the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial after completion of 5 years' adjuvant treatment for breast cancer Lancet 2005;365: 60-62.
-
(2005)
Lancet
, vol.365
, pp. 60-62
-
-
Howell, A.1
Cuzick, J.2
Baum, M.3
-
5
-
-
84868206154
-
Feasibility of preoperative chemotherapy for locally advanced, operable colon cancer: The pilot phase of a randomised controlled trial
-
Foxtrot Collaborative Group
-
Foxtrot Collaborative Group. Feasibility of preoperative chemotherapy for locally advanced, operable colon cancer: The pilot phase of a randomised controlled trial. Lancet Oncol 2012;13: 1152-1160.
-
(2012)
Lancet Oncol
, vol.13
, pp. 1152-1160
-
-
-
6
-
-
77950990798
-
Survival benefit of neoadjuvant chemotherapy in non-small cell lung cancer: An updated meta-analysis of 13 randomized control trials
-
Song WA, Zhou NK, Wang W et al. Survival benefit of neoadjuvant chemotherapy in non-small cell lung cancer: An updated meta-analysis of 13 randomized control trials. J Thorac Oncol 2010;5:510-516.
-
(2010)
J Thorac Oncol
, vol.5
, pp. 510-516
-
-
Song, W.A.1
Zhou, N.K.2
Wang, W.3
-
7
-
-
84871926254
-
High-dose density neoadjuvant chemotherapy in bulky IB cervical cancer
-
Robova H, Rob L, Halaska MJ et al. High-dose density neoadjuvant chemotherapy in bulky IB cervical cancer. Gynecol Oncol 2013;128:49-53.
-
(2013)
Gynecol Oncol
, vol.128
, pp. 49-53
-
-
Robova, H.1
Rob, L.2
Halaska, M.J.3
-
8
-
-
84858681096
-
Pilot study of neoadjuvant chemotherapy with gemcitabine and oral S-1 for resectable pancreatic cancer
-
Tajima H, Ohta T, Kitagawa H et al. Pilot study of neoadjuvant chemotherapy with gemcitabine and oral S-1 for resectable pancreatic cancer. Exp Ther Med 2012;3:787-792.
-
(2012)
Exp Ther Med
, vol.3
, pp. 787-792
-
-
Tajima, H.1
Ohta, T.2
Kitagawa, H.3
-
9
-
-
0031926839
-
Effect of preoperative chemotherapy on the outcome of women with operable breast cancer
-
Fisher B, Bryant J, Wolmark N et al. Effect of preoperative chemotherapy on the outcome of women with operable breast cancer. J Clin Oncol 1998;16:2672-2685.
-
(1998)
J Clin Oncol
, vol.16
, pp. 2672-2685
-
-
Fisher, B.1
Bryant, J.2
Wolmark, N.3
-
10
-
-
36849059118
-
Patient-reported outcomes supporting anticancer product approvals
-
Rock EP, Kennedy DL, Furness MH et al. Patient-reported outcomes supporting anticancer product approvals. J Clin Oncol 2007;25:5094-5099.
-
(2007)
J Clin Oncol
, vol.25
, pp. 5094-5099
-
-
Rock, E.P.1
Kennedy, D.L.2
Furness, M.H.3
-
11
-
-
67650652432
-
I-SPY 2: An adaptive breast cancer trial design in the setting ofneoadjuvantchemotherapy
-
Barker AD, Sigman CC, Kelloff GJ et al. I-SPY 2: An adaptive breast cancer trial design in the setting ofneoadjuvantchemotherapy. Clin Pharmacol Ther 2009;86:97-100.
-
(2009)
Clin Pharmacol Ther
, vol.86
, pp. 97-100
-
-
Barker, A.D.1
Sigman, C.C.2
Kelloff, G.J.3
-
12
-
-
84867879306
-
Lobular histology and response to neoadjuvant chemotherapy in invasive breast cancer
-
Lips EH, Mukhtar RA, Yau C et al. Lobular histology and response to neoadjuvant chemotherapy in invasive breast cancer. Breast Cancer Res Treat 2012;136:35-43.
-
(2012)
Breast Cancer Res Treat
, vol.136
, pp. 35-43
-
-
Lips, E.H.1
Mukhtar, R.A.2
Yau, C.3
-
13
-
-
84856522259
-
Pathologic complete response predicts recurrencefree survival more effectively by cancer subset: Results from the I-SPY 1 TRIAL-CALGB 150007/ 150012, ACRIN 6657
-
Esserman LJ, Berry DA, DeMichele A et al. Pathologic complete response predicts recurrencefree survival more effectively by cancer subset: Results from the I-SPY 1 TRIAL-CALGB 150007/ 150012, ACRIN 6657 J Clin Oncol 2012;30:3242-3249.
-
(2012)
J Clin Oncol
, vol.30
, pp. 3242-3249
-
-
Esserman, L.J.1
Berry, D.A.2
DeMichele, A.3
-
14
-
-
84864018421
-
Preoperative chemotherapy plus trastuzumab, lapatinib, or both in human epidermal growth factor receptor 2-positive operable breast cancer: Results of the randomized phase II CHER-LOB study
-
Guarneri V, Frassoldati A, Bottini A et al. Preoperative chemotherapy plus trastuzumab, lapatinib, or both in human epidermal growth factor receptor 2-positive operable breast cancer: Results of the randomized phase II CHER-LOB study. J Clin Oncol 2012;30:1989-1995.
-
(2012)
J Clin Oncol
, vol.30
, pp. 1989-1995
-
-
Guarneri, V.1
Frassoldati, A.2
Bottini, A.3
-
15
-
-
84855297353
-
Efficacy and safety of neoadjuvantpertuzumabandtrastuzumab in women with locally advanced, inflammatory, or early HER2-positive breastcancer(Neo Sphere):Arandomisedmulticentre, open-label, phase2trial
-
Gianni L, Pienkowski T, Im YH et al. Efficacy and safety of neoadjuvantpertuzumabandtrastuzumab in women with locally advanced, inflammatory, or early HER2-positive breastcancer(Neo Sphere):Arandomisedmulticentre, open-label, phase2trial. Lancet Oncol 2012;13:25-32.
-
(2012)
Lancet Oncol
, vol.13
, pp. 25-32
-
-
Gianni, L.1
Pienkowski, T.2
Im, Y.H.3
-
16
-
-
84862893473
-
Pathological complete response and accelerated drug approval in early breast cancer
-
Prowell TM, Pazdur R. Pathological complete response and accelerated drug approval in early breast cancer. N Engl J Med 2012;366:2438-2441.
-
(2012)
N Engl J Med
, vol.366
, pp. 2438-2441
-
-
Prowell, T.M.1
Pazdur, R.2
-
17
-
-
70149108534
-
Quality of pathologic response and surgery correlate with survival for patients with completely resected bladder cancer after neoadjuvant chemotherapy
-
Sonpavde G, Goldman BH, Speights VO et al. Quality of pathologic response and surgery correlate with survival for patients with completely resected bladder cancer after neoadjuvant chemotherapy. Cancer 2009;115:4104-4109.
-
(2009)
Cancer
, vol.115
, pp. 4104-4109
-
-
Sonpavde, G.1
Goldman, B.H.2
Speights, V.O.3
-
19
-
-
21844432174
-
Adjuvant chemotherapy in invasive bladder cancer:Asystematic reviewandmeta-analysis of individual patient data: Advanced Bladder Cancer (ABC) Meta-analysis Collaboration
-
Advanced Bladder Cancer (ABC) Meta-analysis Collaboration, discussion 199-201
-
Advanced Bladder Cancer (ABC) Meta-analysis Collaboration. Adjuvant chemotherapy in invasive bladder cancer:Asystematic reviewandmeta-analysis of individual patient data: Advanced Bladder Cancer (ABC) Meta-analysis Collaboration. Eur Urol 2005;48:189-199; discussion 199-201.
-
(2005)
Eur Urol
, vol.48
, pp. 189-199
-
-
-
20
-
-
79955969084
-
Randomized phase III trial comparing adjuvant paclitaxel/ gemcitabine/cisplatin (PGC) to observation in patients with resected invasive bladder cancer: Results of the Spanish Oncology Genitourinary Group (SOGUG) 99/01 study
-
Paz-Ares LG, Solsona E, Esteban E, et al. Randomized phase III trial comparing adjuvant paclitaxel/ gemcitabine/cisplatin (PGC) to observation in patients with resected invasive bladder cancer: Results of the Spanish Oncology Genitourinary Group (SOGUG) 99/01 study. J Clin Oncol 2010;28(suppl 18s):LBA4518a.
-
(2010)
J Clin Oncol
, vol.28
, Issue.SUPPL. 18s
-
-
Paz-Ares, L.G.1
Solsona, E.2
Esteban, E.3
-
21
-
-
84857509409
-
Adjuvant chemotherapy with cisplatin and gemcitabine versus chemotherapy at relapse in patients with muscle-invasive bladder cancer submitted to radical cystectomy: An Italian, multicenter, randomized phase III trial
-
Cognetti F, Ruggeri EM, Felici A et al. Adjuvant chemotherapy with cisplatin and gemcitabine versus chemotherapy at relapse in patients with muscle-invasive bladder cancer submitted to radical cystectomy: An Italian, multicenter, randomized phase III trial. Ann Oncol 2012;23:695-700.
-
(2012)
Ann Oncol
, vol.23
, pp. 695-700
-
-
Cognetti, F.1
Ruggeri, E.M.2
Felici, A.3
-
22
-
-
0041429507
-
Neoadjuvant chemotherapy plus cystectomy compared with cystectomy alone for locally advanced bladder cancer
-
Grossman HB, Natale RB, Tangen CM et al. Neoadjuvant chemotherapy plus cystectomy compared with cystectomy alone for locally advanced bladder cancer. N Engl J Med 2003;349:859-866.
-
(2003)
N Engl J Med
, vol.349
, pp. 859-866
-
-
Grossman, H.B.1
Natale, R.B.2
Tangen, C.M.3
-
23
-
-
79957960529
-
International phase III trial assessing neoadjuvant cisplatin, methotrexate, and vinblastine chemotherapy for muscle-invasive bladder cancer: Long-term results of the BA06 30894 trial
-
International Collaboration of Trialists; Medical Research Council Advanced Bladder Cancer Working Party (now the National Cancer Research Institute Bladder Cancer Clinical Studies Group);European Organisation for Research and Treatment of Cancer Genito-Urinary Tract Cancer Group et al
-
International Collaboration of Trialists; Medical Research Council Advanced Bladder Cancer Working Party (now the National Cancer Research Institute Bladder Cancer Clinical Studies Group);European Organisation for Research and Treatment of Cancer Genito-Urinary Tract Cancer Groupet al. International phase III trial assessing neoadjuvant cisplatin, methotrexate, and vinblastine chemotherapy for muscle-invasive bladder cancer: Long-term results of the BA06 30894 trial. J Clin Oncol 2011;29: 2171-2177.
-
(2011)
J Clin Oncol
, vol.29
, pp. 2171-2177
-
-
-
24
-
-
85014013850
-
Neoadjuvant cisplatin, methotrexate, and vinblastine chemotherapy for muscle-invasive bladder cancer: A randomised controlled trial. International Collaboration of Trialists
-
Neoadjuvant cisplatin, methotrexate, and vinblastine chemotherapy for muscle-invasive bladder cancer: A randomised controlled trial. International Collaboration of Trialists. Lancet 1999;354:533-540.
-
(1999)
Lancet
, vol.354
, pp. 533-540
-
-
-
25
-
-
21844450899
-
Neoadjuvant chemotherapy in invasive bladder cancer: Update of a systematic review and meta-analysis of individual patient data: Advanced Bladder Cancer (ABC) Meta-analysis Collaboration
-
Advanced Bladder Cancer (ABC) Meta-analysis Collaboration, discussion 205-206
-
Advanced Bladder Cancer (ABC) Meta-analysis Collaboration. Neoadjuvant chemotherapy in invasive bladder cancer: Update of a systematic review and meta-analysis of individual patient data: Advanced Bladder Cancer (ABC) Meta-analysis Collaboration. Eur Urol 2005;48:202-205;discussion 205-206.
-
(2005)
Eur Urol
, vol.48
, pp. 202-205
-
-
-
26
-
-
0033857218
-
Gemcitabine and cisplatin versus methotrexate, vinblastine, doxorubicin, and cisplatin in advanced or metastatic bladder cancer: Results of a large, randomized, multinational, multicenter, phase III study
-
von der Maase H, Hansen SW, Roberts JT et al. Gemcitabine and cisplatin versus methotrexate, vinblastine, doxorubicin, and cisplatin in advanced or metastatic bladder cancer: Results of a large, randomized, multinational, multicenter, phase III study. J Clin Oncol 2000;18:3068-3077.
-
(2000)
J Clin Oncol
, vol.18
, pp. 3068-3077
-
-
von der Maase, H.1
Hansen, S.W.2
Roberts, J.T.3
-
27
-
-
55549148741
-
A role for neoadjuvant gemcitabine plus cisplatin in muscleinvasive urothelial carcinoma of the bladder: A retrospective experience
-
Dash A, Pettus JA IV, Herr HW et al. A role for neoadjuvant gemcitabine plus cisplatin in muscleinvasive urothelial carcinoma of the bladder: A retrospective experience. Cancer 2008;113:2471-2477.
-
(2008)
Cancer
, vol.113
, pp. 2471-2477
-
-
Dash, A.1
Pettus IV, J.A.2
Herr, H.W.3
-
28
-
-
84883258461
-
Neo adjuvantchemo therapy with gemcitabine/cisplatin vs. methotrexate/vinblastine/doxorubicin/cisplatin for muscle-invasive urothelial carcinoma of the bladder: A retrospective analysis from the University of Southern California
-
[Epub ahead of print]
-
Fairey AS, Daneshmand S, Quinn D et al. Neoadjuvantchemotherapywith gemcitabine/cisplatin vs. methotrexate/vinblastine/doxorubicin/cisplatin for muscle-invasive urothelial carcinoma of the bladder: A retrospective analysis from the University of Southern California. Urol Oncol 2012. [Epub ahead of print].
-
(2012)
Urol Oncol
-
-
Fairey, A.S.1
Daneshmand, S.2
Quinn, D.3
-
29
-
-
60849134836
-
Lack of pathologic down-staging with neoadjuvant chemotherapy for muscle-invasive urothelial carcinoma of the bladder: A contemporary series
-
Weight CJ, Garcia JA, Hansel DE et al. Lack of pathologic down-staging with neoadjuvant chemotherapy for muscle-invasive urothelial carcinoma of the bladder: A contemporary series. Cancer 2009; 115:792-799.
-
(2009)
Cancer
, vol.115
, pp. 792-799
-
-
Weight, C.J.1
Garcia, J.A.2
Hansel, D.E.3
-
30
-
-
34447095141
-
Low incidence of perioperative chemotherapy for stage III bladder cancer 1998 to 2003: A report from the National Cancer Data Base
-
David KA, Milowsky MI, Ritchey J et al. Low incidence of perioperative chemotherapy for stage III bladder cancer 1998 to 2003: A report from the National Cancer Data Base. J Urol 2007;178:451-454.
-
(2007)
J Urol
, vol.178
, pp. 451-454
-
-
David, K.A.1
Milowsky, M.I.2
Ritchey, J.3
-
31
-
-
77957724898
-
Referral and treatment rates of neoadjuvant chemotherapy in muscle-invasive bladder cancer before and after publication of a clinical practice guideline
-
Miles BJ, Fairey AS, Eliasziw M et al. Referral and treatment rates of neoadjuvant chemotherapy in muscle-invasive bladder cancer before and after publication of a clinical practice guideline. Can Urol Assoc J 2010;4:263-267.
-
(2010)
Can Urol Assoc J
, vol.4
, pp. 263-267
-
-
Miles, B.J.1
Fairey, A.S.2
Eliasziw, M.3
-
32
-
-
79955608021
-
Maximizing cure for muscle-invasive bladder cancer: Integration of surgery and chemotherapy
-
Feifer AH, Taylor JM, Tarin TV et al. Maximizing cure for muscle-invasive bladder cancer: Integration of surgery and chemotherapy. Eur Urol 2011; 59:978-984.
-
(2011)
Eur Urol
, vol.59
, pp. 978-984
-
-
Feifer, A.H.1
Taylor, J.M.2
Tarin, T.V.3
-
33
-
-
58149339885
-
Integrating perioperative chemotherapy into the treatment of muscle-invasive bladder cancer: Strategy versus reality
-
Donat SM. Integrating perioperative chemotherapy into the treatment of muscle-invasive bladder cancer: Strategy versus reality. J Natl Compr Canc Netw 2009;7:40-47.
-
(2009)
J Natl Compr Canc Netw
, vol.7
, pp. 40-47
-
-
Donat, S.M.1
-
34
-
-
78650026897
-
Treatment of muscle invasive bladder cancer: Evidence from the National Cancer Database, 2003 to 2007
-
Fedeli U, Fedewa SA, Ward EM. Treatment of muscle invasive bladder cancer: Evidence from the National Cancer Database, 2003 to 2007. J Urol 2011;185:72-78.
-
(2011)
J Urol
, vol.185
, pp. 72-78
-
-
Fedeli, U.1
Fedewa, S.A.2
Ward, E.M.3
-
35
-
-
20444452924
-
Cystectomy for muscle-invasive bladder cancer: Patterns and outcomes of care in the Medicare population
-
Schrag D, Mitra N, Xu F et al. Cystectomy for muscle-invasive bladder cancer: Patterns and outcomes of care in the Medicare population. Urology 2005;65:1118-1125.
-
(2005)
Urology
, vol.65
, pp. 1118-1125
-
-
Schrag, D.1
Mitra, N.2
Xu, F.3
-
36
-
-
78650972192
-
Contemporary use of perioperative cisplatin-based chemotherapy in patients with muscle-invasive bladder cancer
-
Raj GV, Karavadia S, Schlomer B et al. Contemporary use of perioperative cisplatin-based chemotherapy in patients with muscle-invasive bladder cancer. Cancer 2011;117:276-282.
-
(2011)
Cancer
, vol.117
, pp. 276-282
-
-
Raj, G.V.1
Karavadia, S.2
Schlomer, B.3
-
37
-
-
79959191493
-
Treatment of patients with metastatic urothelial cancer "unfit" for Cisplatin-based chemotherapy
-
Galsky MD, Hahn NM, Rosenberg J et al. Treatment of patients with metastatic urothelial cancer "unfit" for Cisplatin-based chemotherapy. J Clin Oncol 2011;29:2432-2438.
-
(2011)
J Clin Oncol
, vol.29
, pp. 2432-2438
-
-
Galsky, M.D.1
Hahn, N.M.2
Rosenberg, J.3
-
38
-
-
49449104088
-
Prevalence of hearing loss and differences by demographic characteristicsamong US adults: Data from the National Health and Nutrition Examination Survey, 1999-2004
-
Agrawal Y, Platz EA, Niparko JK. Prevalence of hearing loss and differences by demographic characteristicsamong US adults: Data from the National Health and Nutrition Examination Survey, 1999-2004. Arch Intern Med 2008;168:1522-1530.
-
(2008)
Arch Intern Med
, vol.168
, pp. 1522-1530
-
-
Agrawal, Y.1
Platz, E.A.2
Niparko, J.K.3
-
39
-
-
33645085071
-
Riskand predictors of motor-performance decline in a normally functioning population-based sample of elderly subjects: The Italian Longitudinal Study on Aging
-
Inzitari M, Carlo A, Baldereschi M et al. Riskand predictors of motor-performance decline in a normally functioning population-based sample of elderly subjects: The Italian Longitudinal Study on Aging. J Am Geriatr Soc 2006;54:318-324.
-
(2006)
J Am Geriatr Soc
, vol.54
, pp. 318-324
-
-
Inzitari, M.1
Carlo, A.2
Baldereschi, M.3
-
40
-
-
33746298622
-
Impact of renal impairment on eligibility for adjuvant cisplatin-based chemotherapy in patients with urothelial carcinoma of the bladder
-
Dash A, Galsky MD, Vickers AJ et al. Impact of renal impairment on eligibility for adjuvant cisplatin-based chemotherapy in patients with urothelial carcinoma of the bladder. Cancer 2006;107:506-513.
-
(2006)
Cancer
, vol.107
, pp. 506-513
-
-
Dash, A.1
Galsky, M.D.2
Vickers, A.J.3
-
41
-
-
78650920424
-
Baseline renal function status limits patient eligibility to receive perioperative chemotherapy for invasive bladder cancer and is minimally affected by radical cystectomy
-
Canter D, Viterbo R, Kutikov A et al. Baseline renal function status limits patient eligibility to receive perioperative chemotherapy for invasive bladder cancer and is minimally affected by radical cystectomy. Urology 2011;77:160-165.
-
(2011)
Urology
, vol.77
, pp. 160-165
-
-
Canter, D.1
Viterbo, R.2
Kutikov, A.3
-
42
-
-
84856833529
-
Astudy of split-dose cisplatin-based neo-adjuvant chemotherapy in muscle-invasive bladder cancer
-
Hussain SA, Palmer DH, Lloyd B et al. Astudy of split-dose cisplatin-based neo-adjuvant chemotherapy in muscle-invasive bladder cancer. Oncol Lett 2012;3:855-859.
-
(2012)
Oncol Lett
, vol.3
, pp. 855-859
-
-
Hussain, S.A.1
Palmer, D.H.2
Lloyd, B.3
-
43
-
-
26444453688
-
Bladder cancer stage and outcome by array-based comparative genomic hybridization
-
Blaveri E, Brewer JL, Roydasgupta R et al. Bladder cancer stage and outcome by array-based comparative genomic hybridization. Clin Cancer Res 2005;11:7012-7022.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 7012-7022
-
-
Blaveri, E.1
Brewer, J.L.2
Roydasgupta, R.3
-
44
-
-
66149141021
-
PTEN and the PI3-kinase pathway in cancer
-
Chalhoub N, Baker SJ. PTEN and the PI3-kinase pathway in cancer. Annu Rev Pathol 2009;4:127-150.
-
(2009)
Annu Rev Pathol
, vol.4
, pp. 127-150
-
-
Chalhoub, N.1
Baker, S.J.2
-
45
-
-
0032897458
-
Somatic mutation of PTEN in bladder carcinoma
-
Aveyard JS, Skilleter A, Habuchi T et al. Somatic mutation of PTEN in bladder carcinoma. Br J Cancer 1999;80:904-908.
-
(1999)
Br J Cancer
, vol.80
, pp. 904-908
-
-
Aveyard, J.S.1
Skilleter, A.2
Habuchi, T.3
-
46
-
-
63049094489
-
Inactivation of p53 and Pten promotes invasive bladder cancer
-
Puzio-Kuter AM, Castillo-Martin M, Kinkade CW et al. Inactivation of p53 and Pten promotes invasive bladder cancer. Genes Dev 2009;23:675-680.
-
(2009)
Genes Dev
, vol.23
, pp. 675-680
-
-
Puzio-Kuter, A.M.1
Castillo-Martin, M.2
Kinkade, C.W.3
-
47
-
-
73849134249
-
AKT1 mutations in bladder cancer: Identification of a novel oncogenic mutation that can co-operate with E17K
-
Askham JM, Platt F, Chambers PA et al. AKT1 mutations in bladder cancer: Identification of a novel oncogenic mutation that can co-operate with E17K. Oncogene 2010;29:150-155.
-
(2010)
Oncogene
, vol.29
, pp. 150-155
-
-
Askham, J.M.1
Platt, F.2
Chambers, P.A.3
-
48
-
-
79959758262
-
Activation of the PI3K/Akt/mTOR pathway correlates with tumour progression and reduced survival in patients with urothelial carcinoma of the urinary bladder
-
Sun CH, Chang YH, Pan CC. Activation of the PI3K/Akt/mTOR pathway correlates with tumour progression and reduced survival in patients with urothelial carcinoma of the urinary bladder. Histopathology 2011;58:1054-1063.
-
(2011)
Histopathology
, vol.58
, pp. 1054-1063
-
-
Sun, C.H.1
Chang, Y.H.2
Pan, C.C.3
-
49
-
-
84867333656
-
Genome sequencing identifies a basis for everolimus sensitivity
-
Iyer G, Hanrahan AJ, Milowsky MI et al. Genome sequencing identifies a basis for everolimus sensitivity. Science 2012;338:221.
-
(2012)
Science
, vol.338
, pp. 221
-
-
Iyer, G.1
Hanrahan, A.J.2
Milowsky, M.I.3
-
50
-
-
79959712087
-
Ras/ Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR inhibitors: Rationale and importance to inhibiting these pathways inhumanhealth
-
Chappell WH, Steelman LS, Long JM et al. Ras/ Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR inhibitors: Rationale and importance to inhibiting these pathways inhumanhealth. Oncotarget 2011;2:135-164.
-
(2011)
Oncotarget
, vol.2
, pp. 135-164
-
-
Chappell, W.H.1
Steelman, L.S.2
Long, J.M.3
-
51
-
-
0021239267
-
Ha-ras oncogenesare activatedbysomatic alterations inhuman urinary tract tumours
-
Fujita J, Yoshida O, Yuasa Y et al. Ha-ras oncogenesare activatedbysomatic alterations inhuman urinary tract tumours. Nature 1984;309:464-466.
-
(1984)
Nature
, vol.309
, pp. 464-466
-
-
Fujita, J.1
Yoshida, O.2
Yuasa, Y.3
-
52
-
-
69349088824
-
Impact of epidermal growth factor receptor and KRAS mutations on clinical outcomes in previously untreated non-small cell lung cancer patients: Results of an online tumor registry of clinical trials
-
Jackman DM, Miller VA, Cioffredi LA et al. Impact of epidermal growth factor receptor and KRAS mutations on clinical outcomes in previously untreated non-small cell lung cancer patients: Results of an online tumor registry of clinical trials. Clin Cancer Res 2009;15:5267-5273.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 5267-5273
-
-
Jackman, D.M.1
Miller, V.A.2
Cioffredi, L.A.3
-
53
-
-
45149084723
-
First-line gefitinib in patients with advanced non-small-cell lung cancer harboring somatic EGFR mutations
-
Sequist LV, Martins RG, Spigel D et al. First-line gefitinib in patients with advanced non-small-cell lung cancer harboring somatic EGFR mutations. J Clin Oncol 2008;26:2442-2449.
-
(2008)
J Clin Oncol
, vol.26
, pp. 2442-2449
-
-
Sequist, L.V.1
Martins, R.G.2
Spigel, D.3
-
54
-
-
84867083523
-
Phase II trial of cetuximab with or without paclitaxel in patients with advanced urothelial tract carcinoma
-
Wong YN, Litwin S, Vaughn D et al. Phase II trial of cetuximab with or without paclitaxel in patients with advanced urothelial tract carcinoma. J Clin Oncol 2012;30:3545-3551.
-
(2012)
J Clin Oncol
, vol.30
, pp. 3545-3551
-
-
Wong, Y.N.1
Litwin, S.2
Vaughn, D.3
-
55
-
-
77953434938
-
A phase II trial of neoadjuvant erlotinib in patients with muscle-invasive bladder cancer undergoing radical cystectomy: Clinical and pathological results
-
Pruthi RS, Nielsen M, Heathcote S et al. A phase II trial of neoadjuvant erlotinib in patients with muscle-invasive bladder cancer undergoing radical cystectomy: Clinical and pathological results. BJU Int 2010;106:349-354.
-
(2010)
BJU Int
, vol.106
, pp. 349-354
-
-
Pruthi, R.S.1
Nielsen, M.2
Heathcote, S.3
-
56
-
-
34250218955
-
Trastuzumab, paclitaxel, carboplatin, and gemcitabine in advanced human epidermal growth factor receptor-2/neu-positive urothelial carcinoma: Results of a multicenter phase II National Cancer Institute trial
-
Hussain MH, MacVicar GR, Petrylak DP et al. Trastuzumab, paclitaxel, carboplatin, and gemcitabine in advanced human epidermal growth factor receptor-2/neu-positive urothelial carcinoma: Results of a multicenter phase II National Cancer Institute trial. J Clin Oncol 2007;25:2218-2224.
-
(2007)
J Clin Oncol
, vol.25
, pp. 2218-2224
-
-
Hussain, M.H.1
McVicar, G.R.2
Petrylak, D.P.3
-
57
-
-
84876982362
-
Gemcitabine, cisplatin, and sunitinib for metastatic urothelial carcinoma and as preoperative therapy for muscle-invasive bladder cancer
-
Galsky MD, Hahn NM, Powles T et al. Gemcitabine, cisplatin, and sunitinib for metastatic urothelial carcinoma and as preoperative therapy for muscle-invasive bladder cancer. Clin Genitourin Cancer 2013;11:175-181.
-
(2013)
Clin Genitourin Cancer
, vol.11
, pp. 175-181
-
-
Galsky, M.D.1
Hahn, N.M.2
Powles, T.3
-
58
-
-
77949699034
-
Approaches to phase 1 clinical trial design focused on safety, efficiency, and selected patient populations: A report from the clinical trial design task force of the National Cancer Institute Investigational Drug Steering Committee
-
Ivy SP, Siu LL, Garrett-Mayer E et al. Approaches to phase 1 clinical trial design focused on safety, efficiency, and selected patient populations: A report from the clinical trial design task force of the National Cancer Institute Investigational Drug Steering Committee. Clin Cancer Res 2010;16: 1726-1736.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 1726-1736
-
-
Ivy, S.P.1
Siu, L.L.2
Garrett-Mayer, E.3
-
59
-
-
67651246671
-
Phase I study of PLX4032: Proof of concept for V600E BRAF mutation as a therapeutic target in human cancer
-
Flaherty K, Puzanov I, Sosman J, et al. Phase I study of PLX4032: Proof of concept for V600E BRAF mutation as a therapeutic target in human cancer. J Clin Oncol 2009;27(suppl 15s):9000a.
-
(2009)
J Clin Oncol
, vol.27
, Issue.SUPPL. 15s
-
-
Flaherty, K.1
Puzanov, I.2
Sosman, J.3
-
60
-
-
34548799629
-
A strategy for predicting the chemosensitivity of human cancers and its application to drug discovery
-
Lee JK, Havaleshko DM, Cho H et al. A strategy for predicting the chemosensitivity of human cancers and its application to drug discovery. Proc Natl Acad Sci U S A 2007;104:13086-13091.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 13086-13091
-
-
Lee, J.K.1
Havaleshko, D.M.2
Cho, H.3
-
61
-
-
77950194890
-
The COXEN principle: Translating signatures of in vitro chemosensitivity into tools for clinical outcome prediction and drug discovery in cancer
-
Smith SC, Baras AS, Lee JK et al. The COXEN principle: Translating signatures of in vitro chemosensitivity into tools for clinical outcome prediction and drug discovery in cancer. Cancer Res 2010;70: 1753-1758.
-
(2010)
Cancer Res
, vol.70
, pp. 1753-1758
-
-
Smith, S.C.1
Baras, A.S.2
Lee, J.K.3
-
62
-
-
84856834094
-
The future of drug development in urothelial cancer
-
Dreicer R. The future of drug development in urothelial cancer. J Clin Oncol 2012;30:473-475.
-
(2012)
J Clin Oncol
, vol.30
, pp. 473-475
-
-
Dreicer, R.1
|