Structural properties of non-traditional drug targets present new challenges for virtual screening

Journal of Chemical Information and Modeling

Volumn 53, Issue 8, 2013, Pages 2073-2081

  Gowthaman, Ragul ^a   Deeds, Eric J ^a   Karanicolas, John ^a  

^a UNIVERSITY OF KANSAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATOMS; BINDING ENERGY; BIOCHEMISTRY; COLLECTOR EFFICIENCY; EFFICIENCY; LIGANDS; NUCLEIC ACIDS;

CONFORMATIONAL FLUCTUATIONS; ORAL BIOAVAILABILITIES; PROTEIN INTERACTION SITES; PROTEIN-PROTEIN INTERACTIONS; SIGNALING PROTEINS; SMALL MOLECULE INHIBITOR; THERAPEUTIC INTERVENTION; VIRTUAL SCREENING;

PROTEINS;

LIGAND; PROTEIN; PROTEIN BINDING;

BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER INTERFACE; DRUG EFFECTS; DRUG SCREENING; METABOLISM; MOLECULARLY TARGETED THERAPY; PROCEDURES; PROTEIN CONFORMATION; ARTICLE; DRUG EFFECT; METHODOLOGY; PROTEIN BINDING;

BINDING SITES; DRUG EVALUATION, PRECLINICAL; LIGANDS; MODELS, MOLECULAR; MOLECULAR TARGETED THERAPY; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEINS; USER-COMPUTER INTERFACE;

EID: 84883217711     PISSN: 15499596     EISSN: 1549960X     Source Type: Journal    
DOI: 10.1021/ci4002316     Document Type: Article

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