An innovative multipartner research program to address detection, assessment and treatment of neonatal infections in low-resource settings

Pediatric Infectious Disease Journal

Volumn 32, Issue 9 SUPPL., 2013, Pages

  Qazi, Shamim Ahmad ^a   Wall, Steve ^b   Brandes, Neal ^c   Engmann, Cyril ^d,e   Darmstadt, Gary L ^e   Bahl, Rajiv ^a  

^a WORLD HEALTH ORGANIZATION   (Switzerland)

^b SAVE THE CHILDREN   (United States)

^c UNITED STATES AGENCY FOR INTERNATIONAL DEVELOPMENT   (United States)

^d UNIVERSITY OF NORTH CAROLINA   (United States)

^e BILL AND MELINDA GATES FOUNDATION   (United States)

Author keywords

Antibiotic treatment; Infection; Innovation; Neonates; Research; Young infants

Indexed keywords

ANTIBIOTIC AGENT;

ANTIBIOTIC THERAPY; BANGLADESH; CLINICAL ASSESSMENT; CONGO; CONSULTATION; DISEASE SEVERITY; DRUG EFFICACY; DRUG SAFETY; GOVERNMENT; HEALTH AUXILIARY; HEALTH CARE DELIVERY; HEALTH PROGRAM; HOME CARE; HUMAN; KENYA; MEDICAL RESEARCH; NEWBORN SEPSIS; NIGERIA; PAKISTAN; PARTICIPATORY RESEARCH; PATIENT REFERRAL; PRACTICE GUIDELINE; PRIORITY JOURNAL; REVIEW; WORLD HEALTH ORGANIZATION;

EID: 84883217101     PISSN: 08913668     EISSN: 15320987     Source Type: Journal    
DOI: 10.1097/INF.0b013e31829ff5e5     Document Type: Review

References (22)

1. Lawn JE, Cousens S, Zupan J; Lancet Neonatal Survival Steering Team. 4 million neonatal deaths: when? where? why? Lancet. 2005;365: 891-900.
2. Liu L, Johnson HL, Cousens S, et al.; Child Health Epidemiology Reference Group of WHO and UNICEF. Global, regional, and national causes of child mortality: An updated systematic analysis for 2010 with time trends since 2000. Lancet. 2012;379: 2151-2161.
3. World Health Organization. Pocket Book of Hospital Care for Children. Guidelines for the Management of Common Illnesses. Second edition. Geneva, Switzerland: World Health Organization; 2013.
4. Waiswa P, Kallander K, Peterson S, et al. Using the three delays model to understand why newborn babies die in eastern Uganda. Trop Med Int Health. 2010;15: 964-972.
5. Engmann C, Adongo P, Akawire Aborigo R, et al. Infant illness spanning the antenatal to early neonatal continuum in rural northern Ghana: local perceptions, beliefs and practices. J Perinatol. 2013;33: 476-481.
6. Zaidi AK, Tikmani SS, Warraich HJ, et al. Community-based treatment of serious bacterial infections in newborns and young infants: A randomized controlled trial assessing three antibiotic regimens. Pediatr Infect Dis J. 2012;31: 667-672.
7. Bang AT, Bang RA, Baitule SB, et al. Effect of home-based neonatal care and management of sepsis on neonatal mortality: field trial in rural India. Lancet. 1999;354: 1955-1961.
8. World Health Organization, UNICEF. WHO/UNICEF Joint Statement - Home Visits for the Newborn Child:A Strategy to Improve Survival. WHO/ FCH/CAH/09.02. Geneva, Switzerland: World Health Organization; 2009.
9. Save the Children/Saving Newborn Lives, USAID World Health Organization. Expert Consultation on Community-Based Approaches for Neonatal Sepsis Management September 26-28, 2007. Meeting Report. London, UK. Save the Children/Saving Newborn Lives, USAID, World Health Organization; 2008. Available at: http://www.harpnet.org/doc/london-sepsis-mtg09-07. pdf. Accessed July 10, 2013.
10. Baqui AH, El-Arifeen S, Darmstadt GL, et al.; Projahnmo Study Group. Effect of community-based newborn-care intervention package implemented through two service-delivery strategies in Sylhet district, Bangladesh: A cluster-randomised controlled trial. Lancet. 2008;371: 1936-1944. (Pubitemid 351778192)
11. Khanal S, Sharma J, GC VS, et al. Community health workers can identify and manage possible infections in neonates and young infants: MINI-a model from Nepal. J Health Popul Nutr. 2011;29: 255-264.
12. Bhandari N, Bahl R, Bhatnagar V, et al. Treating sick young infants in urban slum setting [letter]. Lancet. 1996;347: 1774-1775. (Pubitemid 26187578)
13. The Young Infants Clinical Signs Study Group. Clinical signs that predict severe illness in children under age 2 months: A multicentre study. Lancet. 2008;371: 135-142.
14. Darmstadt GL, Baqui AH, Choi Y, et al.; Bangladesh Projahnmo-2 (Mirzapur) Study Group. Validation of community health workers' assessment of neonatal illness in rural Bangladesh. Bull World Health Organ. 2009;87: 12-19.
15. Darmstadt GL, Baqui AH, Choi Y, et al.; Bangladesh Projahnmo-2 (Mirzapur) Study. Validation of a clinical algorithm to identify neonates with severe illness during routine household visits in rural Bangladesh. Arch Dis Child. 2011;96: 1140-1146.
16. Bang AT, Bang RA, Reddy MH, et al. Simple clinical criteria to identify sepsis or pneumonia in neonates in the community needing treatment or referral. Pediatr Infect Dis J. 2005;24: 335-341. (Pubitemid 40525342)
17. World Health Organization, UNICEF. Integrated Management of Childhood Illness (IMCI) Chart Booklet. Geneva, Switzerland: World Health Organization; 2008.
18. Wall SN, Mazzeo CI, Adejuigbe EA, et al. Ensuring quality in the AFRINEST and SATT trials: clinical standardization and monitoring. Pediatr Infect Dis J. 2013;32 (suppl):S39-S45.
19. Baqui AH, Saha SK, Ahmed ASMN, et al. Safety and efficacy of simplified antibiotic regimens for outpatient treatment of clinical serious infection among neonates and young infants aged 0-59 days in Bangladesh: design of a randomized controlled trial. Pediatr Infect Dis J. 2013;32 (suppl):S12-S18.
20. Zaidi AKM, Tikmani SS, Sultana S, et al. Simplified antibiotic regimens for the management of clinically diagnosed severe infections in newborns and young infants in first-level facilities in Karachi, Pakistan: study design for an outpatient randomized controlled equivalence trial. Pediatr Infect Dis J. 2013;32 (suppl):S19-S25.
21. AFRINEST (AFRIcan NEonatal Sepsis Trial) Group. Simplified regimens for management of neonates and young infants with clinical severe infection in situations when hospital admission is not possible: study protocol for a randomized, open-label equivalence trial. Pediatr Infect Dis J. 2013;32 (suppl):S26-S32.
22. AFRINEST (AFRIcan NEonatal Sepsis Trial) Group. Treatment of fast breathing in neonates and young Infants with oral amoxicillin compared to injectable penicillin-gentamicin combination: Study protocol for a randomized, open-label equivalence trial. Pediatr Infect Dis J. 2013;32 (suppl):S33-S39.