Waldiomycin, a novel WalK-histidine kinase inhibitor from Streptomyces sp. MK844-mF10

Journal of Antibiotics

Volumn 66, Issue 8, 2013, Pages 459-464

  Igarashi, Masayuki ^a   Watanabe, Takafumi ^b   Hashida, Tomohiro ^a   Umekita, Maya ^a   Hatano, Masaki ^a   Yanagida, Yohei ^b   Kino, Hirokazu ^b   Kimura, Tomoyuki ^a   Kinoshita, Naoko ^a   Inoue, Kunio ^a   Sawa, Ryuichi ^a   Nishimura, Yoshio ^a   Utsumi, Ryutaro ^b   Nomoto, Akio ^a  

^a INSTITUTE OF MICROBIAL CHEMISTRY   (Japan)

^b KINKI UNIVERSITY   (Japan)

Author keywords

Angucycline antibiotics; Histidine kinase inhibitor; Streptomyces sp.; Two component signal transduction systems; WalK WalR

Indexed keywords

ANGUCYCLINE DERIVATIVE; ANTIBIOTIC AGENT; AQUAYAMYCIN; PROTEIN HISTIDINE KINASE; RABELOMYCIN; SAKYOMICIN A; UNCLASSIFIED DRUG; WALDIOMYCIN;

ANTIBACTERIAL ACTIVITY; ARTICLE; AUTOPHOSPHORYLATION; BACILLUS SUBTILIS; BACTERIAL STRAIN; CARBON NUCLEAR MAGNETIC RESONANCE; CRYSTAL STRUCTURE; DRUG ISOLATION; DRUG STRUCTURE; ENZYME INHIBITION; GENE SEQUENCE; IC 50; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; STAPHYLOCOCCUS AUREUS; STREPTOMYCES;

ANTI-BACTERIAL AGENTS; BACILLUS SUBTILIS; INHIBITORY CONCENTRATION 50; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MICROBIAL SENSITIVITY TESTS; PROTEIN KINASE INHIBITORS; PROTEIN KINASES; QUINONES; SIGNAL TRANSDUCTION; STREPTOMYCES;

EID: 84883214488     PISSN: 00218820     EISSN: 18811469     Source Type: Journal    
DOI: 10.1038/ja.2013.33     Document Type: Article

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