Bioeffects of static magnetic fields: Oxidative stress, genotoxic effects, and cancer studies

BioMed Research International

Volumn 2013, Issue , 2013, Pages

  Ghodbane, Soumaya ^a   Lahbib, Aida ^a   Sakly, Mohsen ^a   Abdelmelek, Hafedh ^a  

^a UNIVERSITY OF CARTHAGE   (Tunisia)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ALPHA TOCOPHEROL; ANTIOXIDANT; CARBON TETRACHLORIDE; CATALASE; COPPER ZINC SUPEROXIDE DISMUTASE; DNA; FLUORESCENT DYE; FREE RADICAL; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; MALONALDEHYDE; MANGANESE SUPEROXIDE DISMUTASE; METALLOTHIONEIN; MITOMYCIN; NITRIC OXIDE; NITROGEN; OXYGEN; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; RETINOL; SELENIUM; SINGLET OXYGEN; SODIUM SELENITE; SUPEROXIDE; UNCLASSIFIED DRUG; UNINDEXED DRUG; ZINC; ZINC CHLORIDE; ZINPYR 1;

ANTIOXIDANT ACTIVITY; APOPTOSIS; BLOOD SAMPLING; BRAIN; CALCIUM TRANSPORT; CANCER CELL CULTURE; CARCINOGENESIS; CELL CULTURE; CELL FRACTIONATION; CELL LINE; CELL TYPE; CELL VIABILITY; COMET ASSAY; DIET SUPPLEMENTATION; DNA DAMAGE; DNA REPAIR; ENZYME ACTIVITY; FENTON REACTION; FRONTAL CORTEX; GENOTOXICITY; HIPPOCAMPUS; HUMAN; IN VITRO STUDY; LIPID PEROXIDATION; LYMPHOCYTE; MAGNETIC FIELD; NEOPLASM; NICK END LABELING; NONHUMAN; OXIDATIVE STRESS; PRACTICE GUIDELINE; REVIEW; SAFETY; SINGLE DRUG DOSE; SOMATIC MUTATION; SPERMATOZOON; STATIC MAGNETIC FIELD; SYSTEMS BIOLOGY; CELL PROLIFERATION; CELL TRANSFORMATION; METABOLISM; RADIATION RESPONSE; RADIATION EXPOSURE;

APOPTOSIS; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; DNA DAMAGE; FREE RADICALS; HUMANS; MAGNETIC FIELDS; OXIDATIVE STRESS;

EID: 84883192498     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2013/602987     Document Type: Review

References (109)

1. Saunders R., Static magnetic fields: animal studies. Progress in Biophysics and Molecular Biology 2005 87 2-3 225 239 2-s2.0-8844280947 10.1016/j.pbiomolbio.2004.09.001
2. Markov M. S., 'Biological windows': a tribute to W. Ross Adey. Environmentalist 2005 25 2-4 67 74 2-s2.0-29944433858 10.1007/s10669-005-4268-8
3. Adey W. R., Models of membranes of cerebral cells as substrates for information storage. BioSystems 1977 8 4 163 178 2-s2.0-0017480109
4. Adey W. R., The sequence and energetic of cell membrane coupling to intracellular enzyme systems. Bioelectrochemistry and Bioenergetics 1986 15 3 447 456 2-s2.0-38249040128
5. Markov M. S., Bender M., Electromagnetic field influence on membranes. Interfacial Phenomena in Biological System 1991 Marcel Dekker 171 192
6. World Health Organization, Static Fields. Environmental Health Criteria, 232, Geneva, Switzerland, 2006
7. Colbert A. P., Souder J., Markov M., Static magnetic field therapy: methodological challenges to conducting clinical trials. Environmentalist 2009 29 2 177 185 2-s2.0-63449134122 10.1007/s10669-008-9203-3
8. Hashish A. H., El-Missiry M. A., Abdelkader H. I., Abou-Saleh R. H., Assessment of biological changes of continuous whole body exposure to static magnetic field and extremely low frequency electromagnetic fields in mice. Ecotoxicology and Environmental Safety 2008 71 3 895 902 2-s2.0-53049088893 10.1016/j.ecoenv.2007.10.002
9. McLean M. J., Holcomb R. R., Wamil A. W., Pickett J. D., Cavopol A. V., Blockade of sensory neuron action potentials by a static magnetic field in the 10 mT range. Bioelectromagnetics 1995 16 1 20 32 2-s2.0-0029207286
10. Markov M. S., Therapeutic application of static magnetic fields. Environmentalist 2007 27 4 457 463 2-s2.0-35348866725 10.1007/s10669-007-9072-1
11. Sahebjamei H., Abdolmaleki P., Ghanati F., Effects of magnetic field on the antioxidant enzyme activities of suspension-cultured tobacco cells. Bioelectromagnetics 2007 28 1 42 47 2-s2.0-33845919345 10.1002/bem.20262
12. Zhao G., Chen S., Wang L., Zhao Y., Wang J., Wang X., Zhang W., Wu R., Wu L., Wu Y., Xu A., Cellular ATP content was decreased by a homogeneous 8.5 T static magnetic field exposure: role of reactive oxygen species. Bioelectromagnetics 2011 32 2 94 101 2-s2.0-78651269472 10.1002/bem.20617
13. Ueno S., Shigemitsu T., Barnes F. S., Greenebaum B., Biological effects of static magnetic fields. Handbook of Biological Effects of Electromagnetic Fields: Bioengineering and Biophysical Aspects of Electromagnetic Fields 2007 3rd Boca Raton, Fla, USA CRC Press
14. Ueno S., Harada K., Experimental difficulties in observing the effects of magnetic fields on biological and chemical processes. IEEE Transactions on Magnetics 1986 22 5 868 873 2-s2.0-0022772080
15. McLauchlan K. A., Steiner U. E., The spin correlated radical pair as a reaction intermediate. Molecular Physics 1991 73 2 241 263 10.1080/ 00268979100101181
16. Connor J. R., Menzies S. L., Cellular management of iron in the brain. Journal of the Neurological Sciences 1995 134, supplement 33 44 2-s2.0-0029433318 10.1016/0022-510X(95)00206-H
17. Markesbery W. R., Oxidative stress hypothesis in Alzheimer's disease. Free Radical Biology and Medicine 1997 23 1 134 147 2-s2.0-0030915855 10.1016/S0891-5849(96)00629-6
18. Koppenol W. H., The Haber-Weiss cycle-70 years later. Redox Report 2001 6 4 229 234 2-s2.0-0034793688 10.1179/135100001101536373
19. International Commission on Non-Ionizing Radiation Protection (ICNIRP), Guidelines on limits of exposure to static magnetic fields. Health Physics 2009 96 4 504 514 10.1097/01.HP.0000343164.27920.4a
20. Mohtat N., Cozens F. L., Hancock-Chen T., Scaiano J. C., McLean J., Kim J., Magnetic field effects on the behavior of radicals in protein and DNA environments. Photochemistry and Photobiology 1998 67 1 111 118 2-s2.0-0031613310
21. Zhang Q. M., Tokiwa M., Doi T., Nakahara T., Chang P.-W., Nakamura N., Hori M., Miyakoshi J., Yonei S., Strong static magnetic field and the induction of mutations through elevated production of reactive oxygen species in Escherichia coli soxR. International Journal of Radiation Biology 2003 79 4 281 286 2-s2.0-0038434174 10.1080/0955300031000096289
22. Okano H., Effects of static magnetic fields in biology: role of free radicals. Frontiers in Bioscience 2008 13 16 6106 6125 2-s2.0-52049101320
23. Dini L., Phagocytosis of dying cells: influence of smoking and static magnetic fields. Apoptosis 2010 15 9 1147 1164 2-s2.0-77956943160 10.1007/s10495-010-0490-z
24. Miyakoshi J., Effects of static magnetic fields at the cellular level. Progress in Biophysics and Molecular Biology 2005 87 2-3 213 223 2-s2.0-8844263910 10.1016/j.pbiomolbio.2004.08.008
25. AGNIR, ELF electromagnetic fields and the risk of cancer. Report of an Advisory Group on Non-Ionising Radiation. Documents of the NRPB 2001 12 1
26. WHO, Magnetic Fields, Environmental Health Criteria 69. World Health Organisation, Geneva, Switzerland, 1987
27. Kowalczuk C. I., Sienkiewicz Z. J., Saunders R. D., Biological effects of exposure to non-ionising electromagnetic fields and radiation. I. Static electric and magnetic fields. 1991 NRPB-R238 Chilton, Wis, USA NRPB
28. ICNIRP, Guidelines on limits of exposure to static magnetic fields. Health Physics 1994 66 1 100 106
29. ICNIRP, Matthes R., Bernhardt J. H., Repacholi M. H., Biological effects of static and ELF electric and magnetic fields. Proceedings of the International Seminar on Biological Effects of Static and ELF Electric and Magnetic Fields and Related Health Risks, Bologna, Italy (ICNIRP '97) 1997 4 München, Germany Märkl-Druck
30. Repacholi M. H., Greenebaum B., Interaction of static and extremely low frequency electric and magnetic fields with living systems: health effects and research needs. Bioelectromagnetics 1999 20 3 133 160
31. International Agency for Research on Cancer (IARC), IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. Non-Ionising Radiation. Part 1: Static and Extremely Low Frequency (ELF) Electric and Magnetic Fields 2002 80 Lyon, France IARC
32. ICNIRP, Matthes R., McKinlay A. F., Bernhardt J. H., Vecchia P., Veyret B., Exposure to static and low frequency electromagnetic fields. Biological Effects and Health Consequences (0-100 kHz) (ICNIRP '03) 2003 13 München, Germany Märkl-Druck
33. McKinlay A. F., Allen S. G., Cox R., Review of the scientific evidence for limiting exposure to electromagnetic fields (0-300 GHz). Documents of the NRPB 2004 15 3
34. Dini L., Abbro L., Bioeffects of moderate-intensity static magnetic fields on cell cultures. Micron 2005 36 3 195 217 2-s2.0-13944283286 10.1016/j.micron.2004.12.009
35. Phillips J. L., Singh N. P., Lai H., Electromagnetic fields and DNA damage. Pathophysiology 2009 16 2-3 79 88 2-s2.0-67650695675 10.1016/j.pathophys.2008.11.005
36. Ueno S., Okano H., Static, low-frequency, and pulsed magnetic fields in biological systems. Electromagnetic Fields in Biological Systems 2012 chapter 3 Taylor & Francis Group, LLC 115 196
37. Engström S., Barnes F. S., Greenebaum B., Magnetic field effects on free radical reactions in biology. Handbook of Biological Effects of Electromagnetic Fields: Bioengineering and Biophysical Aspects of Electromagnetic Fields 2007 3rd Boca Raton, Fla, USA CRC Press
38. Nathan C., Nitric oxide as a secretory product of mammalian cells. The FASEB Journal 1992 6 12 3051 3064 2-s2.0-0026629902
39. Lander H. M., An essential role for free radicals and derived species in signal transduction. The FASEB Journal 1997 11 2 118 124 2-s2.0-0031036917
40. Thannickal V. J., Fanburg B. L., Reactive oxygen species in cell signaling. American Journal of Physiology 2000 279 6 L1005 L1028 2-s2.0-0034533082
41. Brocklehurst B., McLauchlan K. A., Free radical mechanism for the effects of environmental electromagnetic fields on biological systems. International Journal of Radiation Biology 1996 69 1 3 24 2-s2.0-0029870678 10.1080/095530096146147
42. Amara S., Abdelmelek H., Garrel C., Guiraud P., Douki T., Ravanat J.-L., Favier A., Sakly M., Ben Rhouma K., Effects of subchronic exposure to static magnetic field on testicular function in rats. Archives of Medical Research 2006 37 8 947 952 2-s2.0-33749614150 10.1016/j.arcmed.2006.06.004
43. Amara S., Douki T., Garel C., Favier A., Sakly M., Rhouma K. B., Abdelmelek H., Effects of static magnetic field exposure on antioxidative enzymes activity and DNA in rat brain. General Physiology and Biophysics 2009 28 3 260 265 2-s2.0-72949095715 10.4149/gpb-2009-03-260
44. Amara S., Douki T., Ravanat J. L., Garrel C., Guiraud P., Favier A., Sakly M., Rhouma K. B., Abdelmelek H., Influence of a static magnetic field (250 mT) on the antioxidant response and DNA integrity in THP1 cells. Physics in Medicine and Biology 2007 52 4 889 898 2-s2.0-34247135084 10.1088/0031-9155/52/ 4/002
45. Chater S., Abdelmelek H., Douki T., Garrel C., Favier A., Sakly M., Ben Rhouma K., Exposure to static magnetic field of pregnant rats induces hepatic GSH elevation but not oxidative DNA damage in liver and kidney. Archives of Medical Research 2006 37 8 941 946 2-s2.0-33749648117 10.1016/j.arcmed.2006.05. 010
46. Ghodbane S., Amara S., Garrel C., Arnaud J., Ducros V., Favier A., Sakly M., Abdelmelek H., Selenium supplementation ameliorates static magnetic field-induced disorders in antioxidant status in rat tissues. Environmental Toxicology and Pharmacology 2011 31 1 100 106 2-s2.0-78650205293 10.1016/j.etap.2010.09.010
47. Kula B., Sobczak A., Kuśka R., Effects of static and ELF magnetic fields on free-radical processes in rat liver and kidney. Electromagnetic Biology and Medicine 2000 19 1 99 105 2-s2.0-0346047179
48. Zmyslony M., Jajte J., Rajkowska E., Szmigielski S., Weak (5 MT) static magnetic field stimulates lipid peroxidation in isolated rat liver microsomes in vitro. Electro- and Magnetobiology 1998 17 2 109 113 2-s2.0-0346311450
49. Ghodbane S., Amara S., Arnaud J., Garrel C., Faure H., Favier A., Sakly M., Abdelmelek H., Effect of selenium pre-treatment on plasma antioxidant vitamins A (retinol) and e (α -tocopherol) in static magnetic field-exposed rats. Toxicology and Industrial Health 2011 27 10 949 955 2-s2.0-81255128798 10.1177/0748233711401261
50. Amara S., Abdelmelek H., Garrel C., Guiraud P., Douki T., Ravanat J.-L., Favier A., Sakly M., Ben Rhouma K., Zinc supplementation ameliorates static magnetic field-induced oxidative stress in rat tissues. Environmental Toxicology and Pharmacology 2007 23 2 193 197 2-s2.0-33846012872 10.1016/j.etap.2006.09. 001
51. 2+ uptake in rat thymocytes: dependence on mitogen activation. FEBS Letters 1990 271 1-2 157 160 2-s2.0-0025109983 10.1016/0014-5793(90)80396-Z
52. Abdelmelek H., Molnar A., Servais S., Cottet-Emard J. M., Pequignot J. M., Favier R., Sakly M., Skeletal muscle HSP72 and norepinephrine response to static magnetic field in rat. Journal of Neural Transmission 2006 113 7 821 827 2-s2.0-33745481982 10.1007/s00702-005-0364-7
53. Chater S., Abdelmelek H., Couton D., Effects of sub-acute exposure to magnetic field on synthesis of plasma corticosterone and liver metallothionein levels in female rats. Pakistan Journal of Medical Sciences 2004 20 3 219 223 2-s2.0-4644259347
54. Chater S., Abdelmelek H., Couton D., Joulin V., Sakly M., Ben Rhouma K., Sub-acute exposure to magnetic field induced apoptosis in thymus female rats. Pakistan Journal of Medical Sciences 2005 21 3 292 297 2-s2.0-25644459989
55. Agay D., Anderson R. A., Sandre C., Bryden N. A., Alonso A., Roussel A. M., Chancerelle Y., Alterations of antioxidant trace elements (Zn, Se, Cu) and related metallo-enzymes in plasma and tissues following burn injury in rats. Burns 2005 31 3 366 371 2-s2.0-14944341744 10.1016/j.burns.2004.11.010
56. Duda D., Grzesik J., Pawlicki K., Changes in liver and kidney concentration of copper, manganese, cobalt and iron rats exposed to static and low-frequency (50 Hz) magnetic fields. Journal of Trace Elements and Electrolytes in Health and Disease 1991 5 3 181 186 2-s2.0-0026043647
57. Monfared A. S., Jorsaraei S. G., Abdi R., Protective effects of vitamins C and E on spermatogenesis of 1.5 tesla magnetic field exposed rats. Journal of Magnetic Resonance Imaging 2009 30 5 1047 1051 2-s2.0-70350449601 10.1002/jmri.21853
58. Jajte J., Zmyślony M., Rajkowska E., Protective effect of melatonin and vitamin E against prooxidative action of iron ions and static magnetic field. Medycyna Pracy 2003 54 1 23 28 2-s2.0-0043268050
59. Sullivan K., Balin A. K., Allen R. G., Effects of static magnetic fields on the growth of various types of human cells. Bioelectromagnetics 2011 32 2 140 147 2-s2.0-78651333680 10.1002/bem.20624
60. 2 in mouse brain homogenates or phosphotidylcholine. Pathophysiology 2001 7 4 283 288 2-s2.0-0035137660 10.1016/S0928-4680(00)00062-6
61. Amara S., Garrel C., Favier A., Ben Rhouma K., Sakly M., Abdelmelek H., Effect of static magnetic field and/or cadmium in the antioxidant enzymes activity in rat heart and skeletal muscle. General Physiology and Biophysics 2009 28 4 414 419 2-s2.0-77349116384 10.4149/gpb-2009-04-414
62. Amara S., Douki T., Garrel C., Favier A., Ben Rhouma K., Sakly M., Abdelmelek H., Effects of static magnetic field and cadmium on oxidative stress and DNA damage in rat cortex brain and hippocampus. Toxicology and Industrial Health 2011 27 2 99 106 2-s2.0-79952292533 10.1177/0748233710381887
63. Chater S., Douki T., Favier A., Garrel C., Sakly M., Abdelmelek H., Influence of static magnetic field on cadmium toxicity: study of oxidative stress and DNA damage in pregnant rat tissues. Electromagnetic Biology and Medicine 2008 27 4 393 401 2-s2.0-57049173420 10.1080/15368370802473463
64. Sirmatel Ö., Sert C., Sirmatel F., Selek Ş., Yokus B., Total antioxidant capacity, total oxidant status and oxidative stress index in the men exposed to 1.5 T static magnetic field. General Physiology and Biophysics 2007 26 2 86 90 2-s2.0-34548808678
65. Satoh M., Tsuji Y., Watanabe Y., Okonogi H., Suzuki Y., Nakagawa M., Shimizu H., Metallothionein content increased in the liver of mice exposed to magnetic fields. Archives of Toxicology 1996 70 5 315 318 2-s2.0-0030020086 10.1007/s002040050280
66. Watanabe Y., Nakagawa M., Miyakoshi Y., Enhancement of lipid peroxidation in the liver of mice exposed to magnetic fields. Industrial Health 1997 35 2 285 290 2-s2.0-0030972822
67. Cintolesi F., Ritz T., Kay C. W. M., Timmel C. R., Hore P. J., Anisotropic recombination of an immobilized photoinduced radical pair in a 50- T magnetic field: a model avian photomagnetoreceptor. Chemical Physics 2003 294 3 385 399 2-s2.0-1642315255 10.1016/S0301-0104(03)00320-3
68. Efimova O., Hore P. J., Role of exchange and dipolar interactions in the radical pair model of the avian magnetic compass. Biophysical Journal 2008 94 5 1565 1574 2-s2.0-41449118551 10.1529/biophysj.107.119362
69. Kay R. W., Geomagnetic storms: association with incidence of depression as measured by hospital admission. The British Journal of Psychiatry 1994 164 3 403 409 2-s2.0-0028299379
70. Berk M., Dodd S., Henry M., Do ambient electromagnetic fields affect behaviour? A demonstration of the relationship between geomagnetic storm activity and suicide. Bioelectromagnetics 2006 27 2 151 155 2-s2.0-33644848825 10.1002/bem.20190
71. Gray J. R., Frith C. H., Parker J. D., In vivo enhancement of chemotherapy with static electric or magnetic fields. Bioelectromagnetics 2000 21 8 575 583 2-s2.0-0034572983
72. Zmyślony M., Palus J., Jajte J., Dziubaltowska E., Rajkowska E., DNA damage in rat lymphocytes treated in vitro with iron cations and exposed to 7 mT magnetic fields (static or 50 Hz). Mutation Research 2000 453 1 89 96 2-s2.0-0343279090 10.1016/S0027-5107(00)00094-4
73. Jajte J., Grzegorczyk J., Zmysacute M., Rajkowska E., Effect of 7 mT static magnetic field and iron ions on rat lymphocytes: apoptosis, necrosis and free radical processes. Bioelectrochemistry 2002 57 2 107 111 2-s2.0-0036021036 10.1016/S1567-5394(02)00059-2
74. Tenuzzo B., Vergallo C., Dini L., Effect of 6 mT static magnetic field on the bcl-2, bax, p53 and hsp70 expression in freshly isolated and in vitro aged human lymphocytes. Tissue and Cell 2009 41 3 169 179 2-s2.0-67349147016 10.1016/j.tice.2008.09.004
75. 2+ influx. The FASEB Journal 1999 13 1 95 102 2-s2.0-0032928918
76. de Nicola M., Cordisco S., Cerella C., Albertini M. C., D'Alessio M., Accorsi A., Bergamaschi A., Magrini A., Ghibelli L., Magnetic fields protect from apoptosis via redox alteration. Annals of the New York Academy of Sciences 2006 1090 59 68 2-s2.0-34247574689 10.1196/annals.1378.006
77. 2+ and functional alterations in lymphocytes and macrophages after in vitro exposure to static magnetic field. Journal of Toxicology and Environmental Health A 1998 54 1 63 76 2-s2.0-0031752119
78. Ishisaka R., Kanno T., Inai Y., Nakahara H., Akiyama J., Yoshioka T., Utsumi K., Effects of a magnetic fields on the various functions of subcellular organelles and cells. Pathophysiology 2000 7 2 149 152 2-s2.0-0034233542 10.1016/S0928-4680(00)00043-2
79. Teodori L., Grabarek J., Smolewski P., Ghibelli L., Bergamaschi A., de Nicola M., Darzynkiewicz Z., Exposure of cells to static magnetic field accelerates loss of integrity of plasma membrane during apoptosis. Cytometry 2002 49 3 113 118 2-s2.0-0036834578 10.1002/cyto.10160
80. Teodori L., Göhde W., Valente M. G., Tagliaferri F., Coletti D., Perniconi B., Bergamaschi A., Cerella C., Ghibelli L., Static magnetic fields affect calcium fluxes and inhibit stress-induced apoptosis in human glioblastoma cells. Cytometry 2002 49 4 143 149 2-s2.0-0042738014 10.1002/cyto.10172
81. Teodori L., Albertini M. C., Uguccioni F., Falcieri E., Rocchi M. B. L., Battistelli M., Coluzza C., Piantanida G., Bergamaschi A., Magrini A., Mucciato R., Accorsi A., Static magnetic fields affect cell size, shape, orientation, and membrane surface of human glioblastoma cells, as demonstrated by electron, optic, and atomic force microscopy. Cytometry A 2006 69 2 75 85 2-s2.0-33645085318 10.1002/cyto.a.20208
82. Potenza L., Martinelli C., Polidori E., Zeppa S., Calcabrini C., Stocchi L., Sestili P., Stocchi V., Effects of a 300 mT static magnetic field on human umbilical vein endothelial cells. Bioelectromagnetics 2010 31 8 630 639 2-s2.0-78349254583 10.1002/bem.20591
83. Hao Q., Wenfang C., Xia A., Qiang W., Ying L., Kun Z., Runguang S., Effects of a moderate-intensity static magnetic field and adriamycin on K562 cells. Bioelectromagnetics 2011 32 3 191 199 2-s2.0-79952056019 10.1002/bem.20625
84. Sarvestani A. S., Abdolmaleki P., Mowla S. J., Ghanati F., Heshmati E., Tavasoli Z., Jahromi A. M., Static magnetic fields aggravate the effects of ionizing radiation on cell cycle progression in bone marrow stem cells. Micron 2010 41 2 101 104 2-s2.0-70649109825 10.1016/j.micron.2009.10.007
85. McCann J., Dietrich F., Rafferty C., Martin A., A critical review of the genotoxic potential of electric and magnetic fields. Mutation Research 1993 297 1 61 95 2-s2.0-0002977072
86. Suzuki Y., Ikehata M., Nakamura K., Nishioka M., Asanuma K., Koana T., Shimizu H., Induction of micronuclei in mice exposed to static magnetic fields. Mutagenesis 2001 16 6 499 501 2-s2.0-0035162377
87. Lee J. W., Kim M. S., Kim Y. J., Choi Y. J., Lee Y., Chung H. W., Genotoxic effects of 3 T magnetic resonance imaging in cultured human lymphocytes. Bioelectromagnetics 2011 32 7 535 542 2-s2.0-80052272620 10.1002/bem.20664
88. Schreiber W. G., Teichmann E. M., Schiffer I., Hast J., Akbari W., Georgi H., Graf R., Hehn M., Spie H. W., Thelen M., Oesch F., Hengstler J. G., Lack of mutagenic and co-mutagenic effects of magnetic fields during magnetic resonance imaging. Journal of Magnetic Resonance Imaging 2001 14 6 779 788 2-s2.0-0035181121 10.1002/jmri.10010
89. Schwenzer N. F., Bantleon R., Maurer B., Kehlbach R., Schraml C., Claussen C. D., Rodegerdts E., Detection of DNA double-strand breaks using γ H2AX after MRI exposure at 3 Tesla: an in vitro study. Journal of Magnetic Resonance Imaging 2007 26 5 1308 1314 2-s2.0-35848941177 10.1002/jmri.21138
90. Okonogi H., Nakagawa M., Tsuji Y., The effects of a 4.7 tesla static magnetic field on the frequency of micronucleated cells induced by mitomycin C. The Tohoku Journal of Experimental Medicine 1996 180 3 209 215 2-s2.0-0030512118 10.1620/tjem.180.209
91. Kimura T., Takahashi K., Suzuki Y., Konishi Y., Ota Y., Mori C., Ikenaga T., Takanami T., Saito R., Ichiishi E., Awaji S., Watanabe K., Higashitani A., The effect of high strength static magnetic fields and ionizing radiation on gene expression and DNA damage in Caenorhabditis elegans. Bioelectromagnetics 2008 29 8 605 614 2-s2.0-57149094293 10.1002/bem.20425
92. Koana T., Okada M. O., Ikehata M., Nakagawa M., Increase in the mitotic recombination frequency in Drosophila melanogaster by magnetic field exposure and its suppression by vitamin E supplement. Mutation Research 1997 373 1 55 60 2-s2.0-0031033152 10.1016/S0027-5107(96)00188-1
93. Graf U., Wurgler F. E., Katz A. J., Somatic mutation and recombination test in Drosophila melanogaster. Environmental Mutagenesis 1984 6 2 153 188 2-s2.0-0021226982
94. Ikehata M., Koana T., Suzuki Y., Shimizu H., Nakagawa M., Mutagenicity and co-mutagenicity of static magnetic fields detected by bacterial mutation assay. Mutation Research 1999 427 2 147 156 2-s2.0-0032968112 10.1016/S0027-5107(99)00087-1
95. Nakahara T., Yaguchi H., Yoshida M., Miyakoshi J., Effects of exposure of CHO-K1 cells to a 10-T static magnetic field. Radiology 2002 224 3 817 822 2-s2.0-0036720382
96. Tofani S., Barone D., Berardelli M., Berno E., Cintorino M., Foglia L., Ossola P., Ronchetto F., Toso E., Eandi M., Static and ELF magnetic fields enhance the in vivo anti-tumor efficacy of cis-platin against lewis lung carcinoma, but not of cyclophosphamide against B16 melanotic melanoma. Pharmacological Research 2003 48 1 83 90 2-s2.0-12444271017 10.1016/S1043- 6618(03)00062-8
97. Sun R. G., Chen W. F., Qi H., Zhang K., Bu T., Liu Y., Wang S.-R., Biologic effects of SMF and paclitaxel on K562 human leukemia cells. General Physiology and Biophysics 2012 31 1 1 10 2-s2.0-84858785124 10.4149/gpb-2012-002
98. Strieth S., Strelczyk D., Eichhorn M. E., Dellian M., Luedemann S., Griebel J., Bellemann M., Berghaus A., Brix G., Static magnetic fields induce blood flow decrease and platelet adherence in tumor microvessels. Cancer Biology & Therapy 2008 7 6 814 819 2-s2.0-56149106581
99. Strelczyk D., Eichhorn M. E., Luedemann S., Brix G., Dellian M., Berghaus A., Strieth S., Static magnetic fields impair angiogenesis and growth of solid tumors in vivo. Cancer Biology and Therapy 2009 8 18 1756 1762 2-s2.0-73249127217
100. Chen W. F., Qi H., Sun R. G., Liu Y., Zhang K., Liu J. Q., Static magnetic fields enhanced the potency of cisplatin on K562 cells. Cancer Biotherapy and Radiopharmaceuticals 2010 25 4 401 408 2-s2.0-77956150924 10.1089/cbr.2009.0743
101. Liu Y., Qi H., Sun R. G., Chen W. F., An investigation into the combined effect of static magnetic fields and different anticancer drugs on K562 cell membranes. Tumori 2011 97 3 386 392 2-s2.0-79960861595 10.1700/912.10039
102. Raylman R. R., Clavo A. C., Wahl R. L., Exposure to strong static magnetic field slows the growth of human cancer cells in vitro. Bioelectromagnetics 1996 17 5 358 363 2-s2.0-0030337909
103. Chionna A., Tenuzzo B., Panzarini E., Dwikat M. B., Abbro L., Dini L., Time dependent modifications of Hep G2 cells during exposure to static magnetic fields. Bioelectromagnetics 2005 26 4 275 286 2-s2.0-18044396145 10.1002/bem.20081
104. Feng S. W., Lo Y. J., Chang W. J., Lin C. T., Lee S. Y., Abiko Y., Huang H. M., Static magnetic field exposure promotes differentiation of osteoblastic cells grown on the surface of a poly-L-lactide substrate. Medical & Biological Engineering & Computing 2010 48 8 793 798 2-s2.0-77955466854 10.1007/s11517-010-0639-5
105. Hsu S. H., Chang J. C., The static magnetic field accelerates the osteogenic differentiation and mineralization of dental pulp cells. Cytotechnology 2010 62 2 143 155 2-s2.0-77955715711 10.1007/s10616-010-9271-3
106. Martino C. F., Portelli L., McCabe K., Hernandez M., Barnes F., Reduction of the Earth's magnetic field inhibits growth rates of model cancer cell lines. Bioelectromagnetics 2010 31 8 649 655 2-s2.0-78349282246 10.1002/bem.20606
107. Yang J. C., Lee S. Y., Chen C. A., Lin C. T., Chen C. C., Huang H. M., The role of the calmodulin-dependent pathway in static magnetic field-induced mechanotransduction. Bioelectromagnetics 2010 31 4 255 261 2-s2.0-77952086800 10.1002/bem.20559
108. Sabo J., Mirossay L., Horovcak L., Sarissky M., Mirossay A., Mojzis J., Effects of static magnetic field on human leukemic cell line HL-60. Bioelectrochemistry 2002 56 1-2 227 231 2-s2.0-0037094036 10.1016/S1567-5394(02) 00027-0
109. Ghibelli L., Cerella C., Cordisco S., Clavarino G., Marazzi S., de Nicola M., Nuccitelli S., D'Alessio M., Magrini A., Bergamaschi A., Guerrisi V., Porfiri L. M., NMR exposure sensitizes tumor cells to apoptosis. Apoptosis 2006 11 3 359 365 2-s2.0-33646389214 10.1007/s10495-006-4001-1