Stable isotope dilution analysis of small molecules with carboxylic acid functions using 18O labeling for HPLC-ESI-MS/MS: Analysis of fumonisin B1

Journal of Agricultural and Food Chemistry

Volumn 61, Issue 33, 2013, Pages 7904-7908

  Bergmann, Dominik ^a   Hübner, Florian ^a   Humpf, Hans Ulrich ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

18O labeling; carboxylic groups; fumonisin B1; Fusarium, mycotoxin; HPLC MS MS; stable isotope dilution analysis

Indexed keywords

CARBOXYLIC GROUP; FUMONISIN; FUSARIUM; HPLC-MS/MS; STABLE ISOTOPE DILUTION;

PROTEINS; RADIOISOTOPES;

MOLECULES;

CARBOXYLIC ACID; FUMONISIN; FUMONISIN B1; OXYGEN;

ARTICLE; CHEMISTRY; ELECTROSPRAY MASS SPECTROMETRY; EVALUATION STUDY; FOOD CONTAMINATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INDICATOR DILUTION CURVE; MAIZE; METHODOLOGY; TANDEM MASS SPECTROMETRY;

CARBOXYLIC ACIDS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FOOD CONTAMINATION; FUMONISINS; INDICATOR DILUTION TECHNIQUES; OXYGEN ISOTOPES; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY; ZEA MAYS;

EID: 84883179699     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf4022702     Document Type: Article

References (19)

1. Rheeder, J. P.; Marasas, W. F. O.; Vismer, H. F. Production of fumonisin analogs by Fusarium species Appl. Environ. Microbiol. 2002, 68, 2101-2105
2. Nielsen, K. F.; Mogensen, J. M.; Johansen, M.; Larsen, T. O.; Frisvad, J. C. Review of secondary metabolites and mycotoxins from the Aspergillus niger group Anal. Bioanal. Chem. 2009, 395, 1225-1242
3. Soriano, J. M.; Dragacci, S. Occurrence of fumonisins in foods Food Res. Int. 2004, 37, 985-1000
4. Marasas, W. F. O. Discovery and occurrence of the fumonisins: a historical perspective Environ. Health Perspect. Suppl. 2001, 109, 239-244
5. Voss, K. A.; Smith, G. W.; Haschek, W. M. Fumonisins: toxicokinetics mechanism of action and toxicity Anim. Feed Sci. Technol. 2007, 137, 299-325
6. Sydenham, E. W.; Thiel, P. G.; Marasas, W. F. O.; Shephard, G. S.; Van Schalkwyk, D. J.; Koch, K. R. Natural occurrence of some Fusarium mycotoxins in corn from low and high esophageal cancer prevalence areas of the Transkei, southern Africa J. Agric. Food Chem. 1990, 38, 1900-1903
7. Marasas, W. F. O.; Riley, R. T.; Hendricks, K. A.; Stevens, V. L.; Sadler, T. W.; Gelineau-Van Waes, J.; Missmer, S. A.; Cabrera, J.; Torres, O.; Gelderblom, W. C. A.; Allegood, J.; Martinez, C.; Maddox, J.; Miller, J. D.; Starr, L.; Sullards, M. C.; Roman, A. V.; Voss, K. A.; Wang, E.; Merrill, A. H. Fumonisins disrupt sphingolipid metabolism, folate transport, and neural tube development in embryo culture and in vivo: a potential risk factor for human neural tube defects among populations consuming fumonisin-contaminated maize J. Nutr. 2004, 134, 711-716
8. European Commission. CommissionRegulation (EC) No. 1881/2006 of 19 December 2006 lastamended by Commission Regulation (EU) No 1058/2012 of 13 November (2012.
9. Trebstein, A.; Lauber, U.; Humpf, H.-U. Analysis of Fusarium toxins via HPLC-MS/MS multimethods: multi methods and strategies for compensation Mycotoxin Res. 2009) 25, 201-213
10. Cramer, B.; Beyer, M.; Humpf, H.-U. Stable isotope labeled mycotoxins as standards for HPLC-MS/MS analysis: review and evaluation of published procedures for the introduction of stable isotopes into mycotoxins. In Mycotoxin Prevention and Control in Agriculture; Appell, M.; Kendra, D. F.; Trucksess, M. W., Eds.; ACS Symposium Series 1031; American Chemical Society: Washington, DC, 2010; pp 265-276.
11. Mears, W. H.; Sobotka, H. Heavy oxygen exchange reactions of proteins and amino acids J. Am. Chem. Soc. 1939, 61, 880-886
12. Bender, M. L.; Stone, R. R.; Dewey, R. S. Kinetics of an isotopic oxygen exchange between substituted benzoic acids and water J. Am. Chem. Soc. 1956, 78, 319-321
13. 18O isotopes into peptides and proteins for quantitative mass spectroscopy analysis Russ. J. Bioorg. Chem. 2011, 37, 719-731
14. Hübner, F.; Harrer, H.; Fraske, A.; Kneifel, S.; Humpf, H.-U. Large scale purification of B-type fumonisins using centrifugal partition chromatography (CPC) Mycotoxin Res. 2012, 28, 37-43
15. Deutsches Institut für Normung e.V. (DIN). DIN 32645 Chemical Analysis: Decision Limit, Detection Limit and Determination Limit; Estimation in Case of Repeatability, Terms, Methods, Evaluation; Beuth Verlag GmbH: Berlin, Germany, 1994.
16. Kleigrewe, K.; Söhnel, A.-C.; Humpf, H.-U. A new high-performance liquid chromatography-tandem mass spectrometry method based on dispersive solid phase extraction for the determination of the mycotoxin fusarin C in corn ears and processed corn samples J. Agric. Food Chem. 2011, 59, 10470-10476
17. Funk, W.; Dammann, V.; Donnevert, G.; Ianelli, S.; Ianelli, E.; Gray, A. Phase I: Establishing a new analytical procedure. In Quality Assurance in Analytical Chemistry, 2 nd ed.; Wiley-VCH: Weinheim, Germany, 2006; pp 9-55.
18. Varga, E.; Glauner, T.; Köppen, R.; Mayer, K.; Sulyok, M.; Schuhmacher, R.; Krska, R.; Berthiller, F. Stable isotope dilution assay for the accurate determination of mycotoxins in maize by UHPLC-MS/MS Anal. Bioanal. Chem. 2012, 402, 2675-2686
19. 13C NMR spectra and its application to the study of oxygen exchange kinetics J. Am. Chem. Soc. 1979, 101, 252-253