A note on the kinetics of enzyme action: A decomposition that highlights thermodynamic effects

FEBS Letters

Volumn 587, Issue 17, 2013, Pages 2772-2777

  Noor, Elad ^a   Flamholz, Avi ^a   Liebermeister, Wolfram ^a,b   Bar Even, Arren ^a   Milo, Ron ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Enzyme kinetics; Michaelis Menten; Reversible reaction; Thermodynamics

Indexed keywords

ALGORITHM; CONCENTRATION (PARAMETERS); DECOMPOSITION; ELASTICITY; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME MECHANISM; ENZYME SUBSTRATE COMPLEX; EQUILIBRIUM CONSTANT; MATHEMATICAL ANALYSIS; MATHEMATICAL MODEL; MICHAELIS CONSTANT; MICHAELIS MENTEN KINETICS; PRIORITY JOURNAL; REVIEW; SENSITIVITY ANALYSIS; THERMODYNAMICS;

ENZYME KINETICS; MICHAELIS-MENTEN; REVERSIBLE REACTION; THERMODYNAMICS;

ALGORITHMS; ENZYMES; KINETICS; MODELS, CHEMICAL; PROTEIN BINDING; THERMODYNAMICS;

EID: 84883054015     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2013.07.028     Document Type: Review

References (26)

1. V. Henri Lois générales de l'action des diastases 1903 Librairie Scientifique A. Hermann
2. L. Michaelis, and M.L. Menten Die Kinetik der Invertinwirkung Biochem. Z. 49 352 1913 333 369
3. G.E. Briggs, and J.B.S. Haldane A note on the kinetics of enzyme action Biochem. J. 19 2 1925 338 339
4. J.B.S. Haldane The Union of Enzyme with its Substrate and related Compounds Enzymes 1930 Longmans, Green and Co. London 28 53 Chapter III
5. A. Cornish-Bowden The origins of enzyme kinetics FEBS Lett. 000 000 2013 000-000
6. A. Cornish-Bowden Fundamentals of Enzyme Kinetics fourth ed. 2012 Wiley VCH
7. J.B.S. Haldane The course of enzymatic reactions, and its mathematical theory Enzymes 1930 Longmans, Green and Co. London 74 92 Chapter V
8. R.A. Alberty, A. Cornish-Bowden, R.N. Goldberg, G.G. Hammes, K. Tipton, and H.V. Westerhoff Recommendations for terminology and databases for biochemical thermodynamics Biophys. Chem. 155 2-3 2011 89 103
9. J.-H.S. Hofmeyr Metabolic regulation: a control analytic perspective J. Bioenerg. Biomembr. 27 5 1995 479 490
10. J.M. Rohwer, and J.-H.S. Hofmeyr Kinetic and thermodynamic aspects of enzyme control and regulation J. Phys. Chem. B 114 49 2010 16280 16289
11. J.G. Reich, and E.E. Sel'kov Energy Metabolism of the Cell: a Theoretical Treatise 1981 Academic Press New York, London
12. P. Morandini Control limits for accumulation of plant metabolites: brute force is no substitute for understanding Plant Biotechnol. J. 2013 1 15
13. J.-H.S. Hofmeyr, and A. Cornish-Bowden The reversible Hill equation: how to incorporate cooperative enzymes into metabolic models Comput. Appl. Biosci. CABIOS 13 4 1997 377 385
14. R.A. Alberty Thermodynamics of Biochemical Reactions vol. 215 2003 John Wiley & Sons Hoboken, NJ
15. A. Fersht Structure and Mechanism in Protein Science: a Guide to Enzyme Catalysis and Protein Folding first ed. 1998 W.H. Freeman
16. H.V. Westerhoff Thermodynamics and Control of Biological Free-energy Transduction 1987 Elsevier Science Ltd.
17. D.A. Beard, and H. Qian Relationship between thermodynamic driving force and one-way fluxes in reversible processes PloS One 2 1 2007 e144
18. F.S. Rolleston A theoretical background to the use of measured concentrations of intermediates in study of the control of intermediary metabolism Curr. Top. Cell. Regul. 5 1972 47 75
19. M. Stitt Control of sucrose synthesis: estimation of free energy changes, investigation of the contribution of equilibrium and non-equilibrium reactions, and estimation of elasticities and flux control coefficients J. Barber, R. Malkin, Techniques and New Developments in Photosynthesis Research 1989 Springer US, Boston, MA
20. H. Kacser, and J.A. Burns The control of flux Symp. Soc. Exp. Biol. 27 1973 65 104
21. R. Heinrich, and T.A. Rapoport A linear steady-state treatment of enzymatic chains. general properties, control and effector strength Eur. J. Biochem. 42 1 1974 89 95
22. R. Heinrich, and S. Schuster The Regulation of Cellular Systems 1996 Chapman & Hall New York
23. D. Fell Understanding the Control of Metabolism 1st ed. 1996 Portland Press
24. J.A. Burns, A. Cornish-Bowden, A.K. Groen, R. Heinrich, H. Kacser, J.W. Porteous, S.M. Rapoport, T.A. Rapoport, J.W. Stucki, J.M. Tager Control analysis of metabolic systems Trends Biochem. Sci. 10 1 1985 16
25. W. Liebermeister, J. Uhlendorf, and E. Klipp Modular rate laws for enzymatic reactions: thermodynamics, elasticities, and implementation Bioinformatics (Oxford, England) 26 12 2010 1528 1534
26. A. Flamholz, E. Noor, A. Bar-Even, W. Liebermeister, and R. Milo Glycolytic strategy as a tradeoff between energy yield and protein cost Proc. Natl. Acad. Sci. USA 110 24 2013 10039 10044