PRDM11 is dispensable for the maintenance and function of hematopoietic stem and progenitor cells

Stem Cell Research

Volumn 11, Issue 3, 2013, Pages 1129-1136

  Thoren, Lina A ^a,b,c   Fog, Cathrine K ^b   Jensen, Klaus T ^b   Buza Vidas, Natalija ^b   CÔme, Christophe ^b   Lund, Anders H ^b   Porse, Bo T ^a,b,c  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c University of Copenhagen   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE INDUCED MATURATION PROTEIN 11; B LYMPHOCYTE INDUCED MATURATION PROTEIN 16; B LYMPHOCYTE INDUCED MATURATION PROTEIN 3; BINDING PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BONE MARROW; BONE MARROW TRANSPLANTATION; CELL DIVISION; CELL FUNCTION; CELL RENEWAL; COMPARATIVE STUDY; CONTROLLED STUDY; HEMATOPOIETIC STEM CELL; HEMATOPOIETIC SYSTEM; LYMPHOID CELL; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; BIOLOGICAL MARKERS; BONE MARROW CELLS; BONE MARROW TRANSPLANTATION; CARRIER PROTEINS; HEMATOPOIETIC STEM CELLS; MEGAKARYOCYTES; MICE; MICE, KNOCKOUT; PLATELET COUNT; REPRESSOR PROTEINS; STEM CELLS; WHOLE-BODY IRRADIATION;

EID: 84883021856     PISSN: 18735061     EISSN: 18767753     Source Type: Journal    
DOI: 10.1016/j.scr.2013.07.009     Document Type: Article

References (17)

1. Aguilo F., Avagyan S., Labar A., Sevilla A., Lee D.F., Kumar P., Lemischka I.R., Zhou B.Y., Snoeck H.W. Prdm16 is a physiologic regulator of hematopoietic stem cells. Blood 2011, 117:5057-5066.
2. Bagger F.O., Rapin N., Theilgaard-Mönch K., Kaczkowski B., Jendholm J., Winther O., Porse B. HemaExplorer: a Web server for easy and fast visualization of gene expression in normal and malignant hematopoiesis. Blood 2012, 119:6394-6395.
3. Bagger F.O., Rapin N., Theilgaard-Mönch K., Kaczkowski B., Thoren L.A., Jendholm J., Winther O., Porse B.T. HemaExplorer: a database of mRNA expression profiles in normal and malignant haematopoiesis Nucleic Acids Res 2013, 41:D1034-D1039. (Database issue).
4. Briknarova K., Atwater D.Z., Glicken J.M., Maynard S.J., Ness T.E. The PR/SET domain in PRDM4 is preceded by a zinc knuckle. Proteins 2011, 79:2341-2345.
5. Chuikov S., Levi B.P., Smith M.L., Morrison S.J. Prdm16 promotes stem cell maintenance in multiple tissues, partly by regulating oxidative stress. Nat. Cell Biol. 2010, 12:999-1006.
6. Deneault E., Cellot S., Faubert A., Laverdure J.P., Fréchette M., Chagraoui J., Mayotte N., Sauvageau M., Ting S.B., Sauvageau G. A functional screen to identify novel effectors of hematopoietic stem cell activity. Cell 2009, 137:369-379.
7. Duhoux F.P., Ameye G., Montano-Almendras C.P., Bahloula K., Mozziconacci M.J., Laibe S. PRDM16 (1p36) translocations define a distinct entity of myeloid malignancies with poor prognosis but may also occur in lymphoid malignancies. Br. J. Haematol. 2012, 156:76-88.
8. Fears S., Mathieu C., Zeleznik-Le N., Huang S., Rowley J.D., Nucifora G. Intergenic splicing of MDS1 and EVI1 occurs in normal tissues as well as in myeloid leukemia and produces a new member of the PR domain family. Proc. Natl. Acad. Sci. U. S. A. 1996, 93:1642-1647.
9. Fog C.K., Galli G.G., Lund A.H. PRDM proteins: important players in differentiation and disease. Bioessays 2012, 34:50-60.
10. Goyama S., Yamamoto G., Shimabe M., Sato T., Ichikawa M., Ogawa S., Chiba S., Kurokawa M. Evi-1 is a critical regulator for hematopoietic stem cells and transformed leukemic cells. Cell Stem Cell 2008, 3:207-220.
11. Kataoka K., Sato T., Yoshimi A., Goyama S., Tsuruta T., Kobayashi H., Shimabe M, Arai S., Nakagawa M., Imai Y., Kumano K., Kumagai K., Kubota N., Kadowaki T., Kurokawa M. Evi1 is essential for hematopoietic stem cell self-renewal, and its expression marks hematopoietic cells with long-term multilineage repopulating activity. J. Exp. Med. 2011, 208:2403-2416.
12. Lugthart S., Gröschel S., Beverloo H.B., Kayser S., Valk P.J., van Zelderen-Bhola S.L., Jan Ossenkoppele G., Vellenga E., van den Berg-de Ruiter E., Schanz U., Verhoef G., Vandenberghe P., Ferrant A., Köhne C.H., Pfreundschuh M., Horst H.A., Koller E., von Lilienfeld-Toal M., Bentz M., Ganser A., Schlegelberger B., Jotterand M., Krauter J., Pabst T., Theobald M., Schlenk R.F., Delwel R., Döhner K., Löwenberg B., Döhner H. Clinical, molecular, and prognostic significance of WHO type inv(3)(q21q26.2)/t(3;3)(q21;q26.2) and various other 3q abnormalities in acute myeloid leukemia. J. Clin. Oncol. 2010, 28:3890-3898.
13. Pronk C.J., Rossi D.J., Månsson R., Attema J.L., Norddahl G.L., Chan C.K., Sigvardsson M., Weissman I.L., Bryder D. Elucidation of the phenotypic, functional, and molecular topography of a myeloerythroid progenitor cell hierarchy. Cell Stem Cell 2007, 1:428-442.
14. Suzukawa K., Parganas E., Gajjar A., Abe T., Takahashi S., Tani K., Asano S., Asou H., Kamada N., Yokota J., Morishita M., Ihle J.N. Identification of a breakpoint cluster region 3' of the ribophorin I gene at 3q21 associated with the transcriptional activation of the EVI1 gene in acute myelogenous leukemias with inv(3)(q21q26). Blood 1994, 84:2681-2688.
15. Warr M.R., Pietras E.M., Passegue E. Mechanisms controlling hematopoietic stem cell functions during normal hematopoiesis and hematological malignancies. Wiley Interdiscip. Rev. Syst. Biol. Med. 2011, 3:681-701.
16. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues 2008, vol. 2. IARC, Lyon. Fourth edition.
17. Zhang Y., Stehling-Sun S., Lezon-Geyda K., Juneja S.C., Coillard L., Chatterjee G., Wuertzer C.A., Camargo F., Perkins A.S. PR-domain-containing Mds1-Evi1 is critical for long-term hematopoietic stem cell function. Blood 2011, 118:3853-3861.