Disease progression modeling using Hidden Markov Models

Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS

Volumn , Issue , 2012, Pages 2845-2848

  Sukkar, Rafid ^a   Katz, Elyse ^b   Zhang, Yanwei ^b   Raunig, David ^c   Wyman, Bradley T ^a  

^a Voxelon Inc   (United States)

^b PFIZER INC   (United States)

^c ICON Medical Imaging   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER'S DISEASE; COGNITIVE IMPAIRMENT; CROSS VALIDATION; DISEASE PROGRESSION; STATISTICAL PATTERN;

HIDDEN MARKOV MODELS;

DISEASES;

ALZHEIMER DISEASE; ARTICLE; DISEASE COURSE; HUMAN; PATHOLOGY; PROBABILITY;

ALZHEIMER DISEASE; DISEASE PROGRESSION; HUMANS; MARKOV CHAINS;

EID: 84882938880     PISSN: 1557170X     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1109/EMBC.2012.6346556     Document Type: Conference Paper

References (11)

1. R. S. Doody, V. Pavlik, P. Massman, S. Routree, E. Darby, and W. Chan, "Predicting Progression of Alzheimer's Disease,", Alzheimer's Research and Therapy, Feb. 2010.
2. M. N. Samtani, M. Farnum, V. Lobanov, E. Yang, N. Raghavan, A. DiBernardo, and V. Narayan, "An Improved Model for Disease Progression in Patients from the Alzheimer's Disease Neuroimaging Initiative," J. Clinical Pharmacology, June 2009.
3. H. M. Fonteijn, M. J. Clarkson, M. Modat, J. Barnes, M. Lehmann, S. Ourselin, N. C. Fox, and D. C. Alexander, "An Event-Based Disease Progression Model and Its Application to Familial Alzheimer's Disease," Lecture Notes in Computer Science, Vol. 6801/2011, pp. 748-759, 2011
4. X. Huang, A. Acero, H.W. Hon, Spoken Language Processing, Prentice Hall PTR, 2001.
5. S.R. Eddy, "Hidden Markov Models and Large-Scale Genome Analysis," Trans. American Crystallographic Assoc., 1997.
6. H. Jianying, M. K. Brown, and W. Turin, "HMM Based Online Handwriting Recognition," IEEE Trans. Pattern Analysis and Machine Intelligence, Vol. 18, pp. 1039-1045, Oct. 1996.
7. http://www.adni-info.org
8. S. M. Nestor, R. Rupsingh, M. Borrie, M. Smith, V. Accomazzi, J. L. Wells, J. Fogarty, and R. Bartha, "Ventricular Enlargement as a Possible Measure of Alzheimer's Disease Progression Validated Using the Alzheimer's Disease Neuroimaging Initiative Database," Brain: a Journal of Neurology, pp. 2443-2354, Sept. 2008.
9. P. Scheltens, D. Leys, F. Barkhof, D. Huglo, H.C. Weinstein, P. Vermersch, M. Kuiper, M. Steinling, E. C. Wolters, and J. Valk, "Atrophy of Medial Temporal Lobes on MRI in "Probable" Alzheimer's Disease and Normal Ageing: Diagnostic Value and Neuropsychological Correlates," Journal of Neurology, Neurosurgery, and Psychiatry, pp. 967-972, 1992.
10. E. Gordon, J. D. Rohrer, L. G. Kim L, R. Omar, M. N. Rossor, N. C. Fox, J. D. Warren, "Measuring Disease Progression in Frontotemporal Lobar Degeneration: a Clinical and MRI Study," Neurology, pp. 666-673, Feb 2010.
11. S. E. O'Bryant, S. C. Waring, C. M. Cullum, J. Hall, L. Lacritz, P. J. Massman, P. J. Lupo, J. S. Reisch, R. Doody, "Staging dementia using Clinical Dementia Rating Scale Sum of Boxes scores," Archives of Neurology, pp. 1091-1095, Aug. 2008.