Metal Accumulation during Aging

Encyclopedia of Neuroscience

Volumn , Issue , 2009, Pages 811-818

  Schipper, H M ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

Aging; Alzheimer's disease; Astrocyte; Heme oxygenase 1; Iron; Metal; Mitochondria; Multiple sclerosis; Neurodegeneration; Oxidative stress; Parkinson's disease

Indexed keywords

EID: 84882884395     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-008045046-9.00132-7     Document Type: Chapter

References (13)

1. Connor J.R. Metals and Oxidative Damage in Neurological Disorders 1997, Plenum Press, New York.
2. Dennery P.A. Regulation and role of heme oxygenase in oxidative injury. Current Topics in Cellular Regulation 2000, 36:181-199.
3. Dwyer B.E., Takeda A., Zhu X., et al. Ferric cycle activity and Alzheimer disease. Current Neurovascular Research 2005, 2:261-267.
4. Halliwell B., Gutteridge J.M.C. Free Radicals in Biology and Medicine 2007, Oxford University Press, Oxford.
5. Heales S.J., Lam A.A., Duncan A.J., et al. Neurodegeneration or neuroprotection: The pivotal role of astrocytes. Neurochemical Research 2004, 29:513-519.
6. Jenner P. Oxidative stress in Parkinson's disease. Annals of Neurology 2003, 53(supplement 3):S26-S36. discussion S36-S28.
7. Ponka P. Hereditary causes of disturbed iron homeostasis in the central nervous system. Annals of the New York Academy of Sciences 2004, 1012:267-281.
8. Reddy P.H., Beal M.F. Are mitochondria critical in the pathogenesis of Alzheimer's disease?. Brain Research Reviews 2005, 49:618-632.
9. Ryter S.W., Tyrrell R.M. The heme synthesis and degradation pathways: Role in oxidant sensitivity. Heme oxygenase has both pro- and antioxidant properties. Free Radical Biology &Medicine 2000, 28:289-309.
10. Schipper H.M. Heme oxygenase-1: Transducer of pathological brain iron sequestration under oxidative stress. Annals of the New York Academy of Sciences 2004, 1012:84-93.
11. Schipper H.M. Brain iron deposition and the free radical-mitochondrial theory of ageing. Ageing Research Reviews 2004, 3:265-301.
12. Schipper H.M. Redox neurology: Visions of an emerging subspecialty. Annals of the New York Academy of Sciences 2004, 1012:342-355.
13. Schipper H.M. Heme oxygenase expression in human central nervous system disorders. Free Radical Biology &Medicine 2004, 37:1995-2011.