메뉴 건너뛰기




Volumn 444, Issue 1-2, 2013, Pages 140-147

Neutralizing antibodies are unable to inhibit direct viral cell-to-cell spread of human cytomegalovirus

Author keywords

Antibodies; Cell to cell spread; CMV; Cytomegalovirus; Hyperimmune globulin; Plaque reduction

Indexed keywords

MONOCLONAL ANTIBODY; NEUTRALIZING ANTIBODY;

EID: 84882824149     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2013.06.002     Document Type: Article
Times cited : (34)

References (42)
  • 1
    • 33747336158 scopus 로고    scopus 로고
    • Role of human cytomegalovirus UL131A in cell type-specific virus entry and release
    • Adler B., Scrivano L., Ruzcics Z., Rupp B., Sinzger C., Koszinowski U. Role of human cytomegalovirus UL131A in cell type-specific virus entry and release. J. Gen. Virol. 2006, 87:2451-2460.
    • (2006) J. Gen. Virol. , vol.87 , pp. 2451-2460
    • Adler, B.1    Scrivano, L.2    Ruzcics, Z.3    Rupp, B.4    Sinzger, C.5    Koszinowski, U.6
  • 2
    • 84864494017 scopus 로고    scopus 로고
    • Editorial commentary: primary maternal cytomegalovirus infection during pregnancy: do we have a treatment option?
    • Adler S.P. Editorial commentary: primary maternal cytomegalovirus infection during pregnancy: do we have a treatment option?. Clin. Infect. Dis. 2012, 55:504-506.
    • (2012) Clin. Infect. Dis. , vol.55 , pp. 504-506
    • Adler, S.P.1
  • 3
    • 0035685727 scopus 로고    scopus 로고
    • Human CMV-IGIV (CytoGam) neutralizes human cytomegalovirus (HCMV) infectivity and prevents intracellular signal transduction after HCMV exposure
    • Andreoni K.A., Wang X., Huong S.M., Huang E.S. Human CMV-IGIV (CytoGam) neutralizes human cytomegalovirus (HCMV) infectivity and prevents intracellular signal transduction after HCMV exposure. Transplant Infect. Dis. 2001, 3(Suppl 2):25-30.
    • (2001) Transplant Infect. Dis. , vol.3 , Issue.SUPPL 2 , pp. 25-30
    • Andreoni, K.A.1    Wang, X.2    Huong, S.M.3    Huang, E.S.4
  • 4
    • 79955509829 scopus 로고    scopus 로고
    • Cytomegalovirus: pathogen, paradigm, and puzzle
    • Boeckh M., Geballe A.P. Cytomegalovirus: pathogen, paradigm, and puzzle. J. Clin. Investig. 2011, 121:1673-1680.
    • (2011) J. Clin. Investig. , vol.121 , pp. 1673-1680
    • Boeckh, M.1    Geballe, A.P.2
  • 5
    • 79551703754 scopus 로고    scopus 로고
    • Rhesus and human cytomegalovirus glycoprotein L are required for infection and cell-to-cell spread of virus but cannot complement each other
    • Bowman J.J., Lacayo J.C., Burbelo P., Fischer E.R., Cohen J.I. Rhesus and human cytomegalovirus glycoprotein L are required for infection and cell-to-cell spread of virus but cannot complement each other. J. Virol. 2011, 85:2089-2099.
    • (2011) J. Virol. , vol.85 , pp. 2089-2099
    • Bowman, J.J.1    Lacayo, J.C.2    Burbelo, P.3    Fischer, E.R.4    Cohen, J.I.5
  • 6
    • 0036719574 scopus 로고    scopus 로고
    • Antibodies, viruses and vaccines
    • Burton D.R. Antibodies, viruses and vaccines. Nat. Rev. Immunol. 2002, 2:706-713.
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 706-713
    • Burton, D.R.1
  • 7
    • 33747762643 scopus 로고    scopus 로고
    • Evidence for direct transfer of cytoplasmic material from infected to uninfected cells during cell-associated spread of human cytomegalovirus
    • Digel M., Sampaio K.L., Jahn G., Sinzger C. Evidence for direct transfer of cytoplasmic material from infected to uninfected cells during cell-associated spread of human cytomegalovirus. J. Clin. Virol. 2006, 37:10-20.
    • (2006) J. Clin. Virol. , vol.37 , pp. 10-20
    • Digel, M.1    Sampaio, K.L.2    Jahn, G.3    Sinzger, C.4
  • 8
    • 0035693272 scopus 로고    scopus 로고
    • Antibody inhibition of cytomegalovirus: the role of natural killer and macrophage effector cells
    • Forthal D.N., Phan T., Landucci G. Antibody inhibition of cytomegalovirus: the role of natural killer and macrophage effector cells. Transplant Infect. Dis. 2001, 3(Suppl 2):31-34.
    • (2001) Transplant Infect. Dis. , vol.3 , Issue.SUPPL 2 , pp. 31-34
    • Forthal, D.N.1    Phan, T.2    Landucci, G.3
  • 9
    • 84864127535 scopus 로고    scopus 로고
    • Antibodies against the gH/gL/UL128/UL130/UL131 complex comprise the majority of the anti-cytomegalovirus (anti-CMV) neutralizing antibody response in CMV hyperimmune globulin
    • Fouts A.E., Chan P., Stephan J.P., Vandlen R., Feierbach B. Antibodies against the gH/gL/UL128/UL130/UL131 complex comprise the majority of the anti-cytomegalovirus (anti-CMV) neutralizing antibody response in CMV hyperimmune globulin. J. Virol. 2012, 86:7444-7447.
    • (2012) J. Virol. , vol.86 , pp. 7444-7447
    • Fouts, A.E.1    Chan, P.2    Stephan, J.P.3    Vandlen, R.4    Feierbach, B.5
  • 10
    • 84864336678 scopus 로고    scopus 로고
    • Antiviral function and efficacy of polyvalent immunoglobulin products against CMV isolates in different human cell lines
    • Frenzel K., Ganepola S., Michel D., Thiel E., Kruger D.H., Uharek L., Hofmann J. Antiviral function and efficacy of polyvalent immunoglobulin products against CMV isolates in different human cell lines. Med. Microbiol. Immunol. 2012, 201:277-286.
    • (2012) Med. Microbiol. Immunol. , vol.201 , pp. 277-286
    • Frenzel, K.1    Ganepola, S.2    Michel, D.3    Thiel, E.4    Kruger, D.H.5    Uharek, L.6    Hofmann, J.7
  • 11
    • 84866625471 scopus 로고    scopus 로고
    • Burden of disease associated with human cytomegalovirus and prospects for elimination by universal immunisation
    • Griffiths P.D. Burden of disease associated with human cytomegalovirus and prospects for elimination by universal immunisation. Lancet Infect. Dis. 2012, 12:790-798.
    • (2012) Lancet Infect. Dis. , vol.12 , pp. 790-798
    • Griffiths, P.D.1
  • 13
    • 0032552033 scopus 로고    scopus 로고
    • Discordant detection of human cytomegalovirus DNA from peripheral blood mononuclear cells, granulocytes and plasma: correlation to viremia and HCMV infection
    • Hamprecht K., Steinmassl M., Einsele H., Jahn G. Discordant detection of human cytomegalovirus DNA from peripheral blood mononuclear cells, granulocytes and plasma: correlation to viremia and HCMV infection. J. Clin. Virol. 1998, 11:125-136.
    • (1998) J. Clin. Virol. , vol.11 , pp. 125-136
    • Hamprecht, K.1    Steinmassl, M.2    Einsele, H.3    Jahn, G.4
  • 14
    • 64049107723 scopus 로고    scopus 로고
    • Human cytomegalovirus glycoprotein B is required for virus entry and cell-to-cell spread but not for virion attachment, assembly, or egress
    • Isaacson M.K., Compton T. Human cytomegalovirus glycoprotein B is required for virus entry and cell-to-cell spread but not for virion attachment, assembly, or egress. J. Virol. 2009, 83:3891-3903.
    • (2009) J. Virol. , vol.83 , pp. 3891-3903
    • Isaacson, M.K.1    Compton, T.2
  • 15
    • 0023264642 scopus 로고
    • Kinetics of expression of herpes simplex virus type 1-specific glycoprotein species on the surfaces of infected murine, simian, and human cells: flow cytometric analysis
    • Jennings S.R., Lippe P.A., Pauza K.J., Spear P.G., Pereira L., Tevethia S.S. Kinetics of expression of herpes simplex virus type 1-specific glycoprotein species on the surfaces of infected murine, simian, and human cells: flow cytometric analysis. J. Virol. 1987, 61:104-112.
    • (1987) J. Virol. , vol.61 , pp. 104-112
    • Jennings, S.R.1    Lippe, P.A.2    Pauza, K.J.3    Spear, P.G.4    Pereira, L.5    Tevethia, S.S.6
  • 16
    • 0346294229 scopus 로고    scopus 로고
    • Specific inhibition of human cytomegalovirus glycoprotein B-mediated fusion by a novel thiourea small molecule
    • Jones T.R., Lee S.W., Johann S.V., Razinkov V., Visalli R.J., Feld B., Bloom J.D., O'Connell J. Specific inhibition of human cytomegalovirus glycoprotein B-mediated fusion by a novel thiourea small molecule. J. Virol. 2004, 78:1289-1300.
    • (2004) J. Virol. , vol.78 , pp. 1289-1300
    • Jones, T.R.1    Lee, S.W.2    Johann, S.V.3    Razinkov, V.4    Visalli, R.J.5    Feld, B.6    Bloom, J.D.7    O'Connell, J.8
  • 17
    • 68249116041 scopus 로고    scopus 로고
    • Prevalence and mortality associated with cytomegalovirus infection in nonimmunosuppressed patients in the intensive care unit
    • Kalil A.C., Florescu D.F. Prevalence and mortality associated with cytomegalovirus infection in nonimmunosuppressed patients in the intensive care unit. Crit. Care Med. 2009, 37:2350-2358.
    • (2009) Crit. Care Med. , vol.37 , pp. 2350-2358
    • Kalil, A.C.1    Florescu, D.F.2
  • 18
    • 34447518917 scopus 로고    scopus 로고
    • Review and meta-analysis of the epidemiology of congenital cytomegalovirus (CMV) infection
    • Kenneson A., Cannon M.J. Review and meta-analysis of the epidemiology of congenital cytomegalovirus (CMV) infection. Rev. Med. Virol. 2007, 17:253-276.
    • (2007) Rev. Med. Virol. , vol.17 , pp. 253-276
    • Kenneson, A.1    Cannon, M.J.2
  • 20
    • 19944405788 scopus 로고    scopus 로고
    • Characterization of human cytomegalovirus glycoprotein-induced cell-cell fusion
    • Kinzler E.R., Compton T. Characterization of human cytomegalovirus glycoprotein-induced cell-cell fusion. J. Virol. 2005, 79:7827-7837.
    • (2005) J. Virol. , vol.79 , pp. 7827-7837
    • Kinzler, E.R.1    Compton, T.2
  • 22
    • 0035987162 scopus 로고    scopus 로고
    • Leukocyte depleted, unscreened blood products give a low risk for CMV infection and disease in CMV seronegative allogeneic stem cell transplant recipients with seronegative stem cell donors
    • Ljungman P., Larsson K., Kumlien G., Aschan J., Barkholt L., Gustafsson-Jernberg A., Lewensohn-Fuchs I., Ringden O. Leukocyte depleted, unscreened blood products give a low risk for CMV infection and disease in CMV seronegative allogeneic stem cell transplant recipients with seronegative stem cell donors. Scand. J. Infect. Dis. 2002, 34:347-350.
    • (2002) Scand. J. Infect. Dis. , vol.34 , pp. 347-350
    • Ljungman, P.1    Larsson, K.2    Kumlien, G.3    Aschan, J.4    Barkholt, L.5    Gustafsson-Jernberg, A.6    Lewensohn-Fuchs, I.7    Ringden, O.8
  • 23
    • 73849089855 scopus 로고    scopus 로고
    • Isolation of human monoclonal antibodies that potently neutralize human cytomegalovirus infection by targeting different epitopes on the gH/gL/UL128-131 A complex
    • Macagno A., Bernasconi N.L., Vanzetta F., Dander E., Sarasini A., Revello M.G., Gerna G., Sallusto F., Lanzavecchia A. Isolation of human monoclonal antibodies that potently neutralize human cytomegalovirus infection by targeting different epitopes on the gH/gL/UL128-131 A complex. J. Virol. 2010, 84:1005-1013.
    • (2010) J. Virol. , vol.84 , pp. 1005-1013
    • Macagno, A.1    Bernasconi, N.L.2    Vanzetta, F.3    Dander, E.4    Sarasini, A.5    Revello, M.G.6    Gerna, G.7    Sallusto, F.8    Lanzavecchia, A.9
  • 24
    • 0020636893 scopus 로고
    • 9-[(1,3-Dihydroxy-2-propoxy)methyl]guanine: a new potent and selective antiherpes agent
    • Martin J.C., Dvorak C.A., Smee D.F., Matthews T.R., Verheyden J.P. 9-[(1,3-Dihydroxy-2-propoxy)methyl]guanine: a new potent and selective antiherpes agent. J. Med. Chem. 1983, 26:759-761.
    • (1983) J. Med. Chem. , vol.26 , pp. 759-761
    • Martin, J.C.1    Dvorak, C.A.2    Smee, D.F.3    Matthews, T.R.4    Verheyden, J.P.5
  • 25
    • 0022004066 scopus 로고
    • Cytomegalovirus early and late membrane antigens detected by antibodies in human convalescent sera
    • Middeldorp J.M., Jongsma J., The T.H. Cytomegalovirus early and late membrane antigens detected by antibodies in human convalescent sera. J. Virol. 1985, 54:240-244.
    • (1985) J. Virol. , vol.54 , pp. 240-244
    • Middeldorp, J.M.1    Jongsma, J.2    The, T.H.3
  • 26
    • 0027448559 scopus 로고
    • Glycoprotein B of human cytomegalovirus promotes virion penetration into cells, transmission of infection from cell to cell, and fusion of infected cells
    • Navarro D., Paz P., Tugizov S., Topp K., La V.J., Pereira L. Glycoprotein B of human cytomegalovirus promotes virion penetration into cells, transmission of infection from cell to cell, and fusion of infected cells. Virology 1993, 197:143-158.
    • (1993) Virology , vol.197 , pp. 143-158
    • Navarro, D.1    Paz, P.2    Tugizov, S.3    Topp, K.4    La, V.J.5    Pereira, L.6
  • 27
    • 0028358238 scopus 로고
    • Human monoclonal anti-cytomegalovirus (CMV) antibody (MSL 109): enhancement of in vitro foscarnet- and ganciclovir-induced inhibition of CMV replication
    • Nokta M., Tolpin M.D., Nadler P.I., Pollard R.B. Human monoclonal anti-cytomegalovirus (CMV) antibody (MSL 109): enhancement of in vitro foscarnet- and ganciclovir-induced inhibition of CMV replication. Antivir. Res. 1994, 24:17-26.
    • (1994) Antivir. Res. , vol.24 , pp. 17-26
    • Nokta, M.1    Tolpin, M.D.2    Nadler, P.I.3    Pollard, R.B.4
  • 28
    • 79952830376 scopus 로고    scopus 로고
    • Human cytomegalovirus pUS27 G protein-coupled receptor homologue is required for efficient spread by the extracellular route but not for direct cell-to-cell spread
    • O'Connor C.M., Shenk T. Human cytomegalovirus pUS27 G protein-coupled receptor homologue is required for efficient spread by the extracellular route but not for direct cell-to-cell spread. J. Virol. 2011, 85:3700-3707.
    • (2011) J. Virol. , vol.85 , pp. 3700-3707
    • O'Connor, C.M.1    Shenk, T.2
  • 29
    • 0031048071 scopus 로고    scopus 로고
    • Cytomegalovirus glycoprotein B-specific antibody analysis using electrochemiluminescence detection-based techniques
    • Ohlin M., Silvestri M., Sundqvist V.A., Borrebaeck C.A. Cytomegalovirus glycoprotein B-specific antibody analysis using electrochemiluminescence detection-based techniques. Clin. Diagn. Lab. Immunol. 1997, 4:107-111.
    • (1997) Clin. Diagn. Lab. Immunol. , vol.4 , pp. 107-111
    • Ohlin, M.1    Silvestri, M.2    Sundqvist, V.A.3    Borrebaeck, C.A.4
  • 30
    • 0027398669 scopus 로고
    • Fine specificity of the human immune response to the major neutralization epitopes expressed on cytomegalovirus gp58/116 (gB), as determined with human monoclonal antibodies
    • Ohlin M., Sundqvist V.A., Mach M., Wahren B., Borrebaeck C.A. Fine specificity of the human immune response to the major neutralization epitopes expressed on cytomegalovirus gp58/116 (gB), as determined with human monoclonal antibodies. J. Virol. 1993, 67:703-710.
    • (1993) J. Virol. , vol.67 , pp. 703-710
    • Ohlin, M.1    Sundqvist, V.A.2    Mach, M.3    Wahren, B.4    Borrebaeck, C.A.5
  • 31
    • 79961023607 scopus 로고    scopus 로고
    • Cytomegalovirus neutralization by hyperimmune and standard intravenous immunoglobulin preparations
    • Planitzer C.B., Saemann M.D., Gajek H., Farcet M.R., Kreil T.R. Cytomegalovirus neutralization by hyperimmune and standard intravenous immunoglobulin preparations. Transplantation 2011, 92:267-270.
    • (2011) Transplantation , vol.92 , pp. 267-270
    • Planitzer, C.B.1    Saemann, M.D.2    Gajek, H.3    Farcet, M.R.4    Kreil, T.R.5
  • 32
    • 0034981916 scopus 로고    scopus 로고
    • In vitro selection of human cytomegalovirus variants unable to transfer virus and virus products from infected cells to polymorphonuclear leukocytes and to grow in endothelial cells
    • Revello M.G., Baldanti F., Percivalle E., Sarasini A., De-Giuli L., Genini E., Lilleri D., Labo N., Gerna G. In vitro selection of human cytomegalovirus variants unable to transfer virus and virus products from infected cells to polymorphonuclear leukocytes and to grow in endothelial cells. J. Gen. Virol. 2001, 82:1429-1438.
    • (2001) J. Gen. Virol. , vol.82 , pp. 1429-1438
    • Revello, M.G.1    Baldanti, F.2    Percivalle, E.3    Sarasini, A.4    De-Giuli, L.5    Genini, E.6    Lilleri, D.7    Labo, N.8    Gerna, G.9
  • 33
    • 30344435010 scopus 로고    scopus 로고
    • Human cytomegalovirus entry into epithelial and endothelial cells depends on genes UL128 to UL150 and occurs by endocytosis and low-pH fusion
    • Ryckman B.J., Jarvis M.A., Drummond D.D., Nelson J.A., Johnson D.C. Human cytomegalovirus entry into epithelial and endothelial cells depends on genes UL128 to UL150 and occurs by endocytosis and low-pH fusion. J. Virol. 2006, 80:710-722.
    • (2006) J. Virol. , vol.80 , pp. 710-722
    • Ryckman, B.J.1    Jarvis, M.A.2    Drummond, D.D.3    Nelson, J.A.4    Johnson, D.C.5
  • 34
    • 54149119141 scopus 로고    scopus 로고
    • Avoiding the void: cell-to-cell spread of human viruses
    • Sattentau Q. Avoiding the void: cell-to-cell spread of human viruses. Nat. Rev. Microbiol. 2008, 6:815-826.
    • (2008) Nat. Rev. Microbiol. , vol.6 , pp. 815-826
    • Sattentau, Q.1
  • 35
    • 58049218907 scopus 로고    scopus 로고
    • Inhibition of cyclooxygenase activity blocks cell-to-cell spread of human cytomegalovirus
    • Schroer J., Shenk T. Inhibition of cyclooxygenase activity blocks cell-to-cell spread of human cytomegalovirus. Proc. Natl. Acad. Sci. USA 2008, 105:19468-19473.
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 19468-19473
    • Schroer, J.1    Shenk, T.2
  • 36
    • 13844313929 scopus 로고    scopus 로고
    • Human cytomegalovirus cell-to-cell spread in the absence of an essential assembly protein
    • Silva M.C., Schroer J., Shenk T. Human cytomegalovirus cell-to-cell spread in the absence of an essential assembly protein. Proc. Natl. Acad. Sci. USA 2005, 102:2081-2086.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 2081-2086
    • Silva, M.C.1    Schroer, J.2    Shenk, T.3
  • 38
    • 84882868708 scopus 로고    scopus 로고
    • Monoclonal Antibody Capable of Binding to Specific Discontinuous Epitope Occuring in AD1 Region of Human Cytomegalovirus gB Glycoprotein, and Antigen-binding Fragment thereof. 10758877.4(WO 2010/114106). 7-10-2010a.
    • Takada, K., Kurino, R., Torashima, T. Monoclonal Antibody Capable of Binding to Specific Discontinuous Epitope Occuring in AD1 Region of Human Cytomegalovirus gB Glycoprotein, and Antigen-binding Fragment thereof. 10758877.4(WO 2010/114106). 7-10-2010a.
    • Takada, K.1    Kurino, R.2    Torashima, T.3
  • 39
    • 84882905593 scopus 로고    scopus 로고
    • Monoclonal Antibody Capable of Binding to Specific Discontinuous Epitpe Occurring in AD1 Region of Human Cytomegalovirus gB Glycoprotein, and Antigen-binding Fragment thereof. (US 2012/0093810 A1). 4-19-2012.
    • Takada, K., Kurino, R., Torashima, T. Monoclonal Antibody Capable of Binding to Specific Discontinuous Epitpe Occurring in AD1 Region of Human Cytomegalovirus gB Glycoprotein, and Antigen-binding Fragment thereof. (US 2012/0093810 A1). 4-19-2012.
    • Takada, K.1    Kurino, R.2    Torashima, T.3
  • 40
    • 84882892697 scopus 로고    scopus 로고
    • Monoclonal Antibody Capable of Binding to AD2 Region of Human Cytomegalovirus gB Glycoprotein, and Antigen-binding Fragment thereof. PCT/JP2010/056033(WO/2010/114105). 7-10-2010b.
    • Takada, K., Kurino, R., Wantanabe, M. Monoclonal Antibody Capable of Binding to AD2 Region of Human Cytomegalovirus gB Glycoprotein, and Antigen-binding Fragment thereof. PCT/JP2010/056033(WO/2010/114105). 7-10-2010b.
    • Takada, K.1    Kurino, R.2    Wantanabe, M.3
  • 41
    • 0030051976 scopus 로고    scopus 로고
    • Role of apical and basolateral membranes in replication of human cytomegalovirus in polarized retinal pigment epithelial cells
    • Tugizov S., Maidji E., Pereira L. Role of apical and basolateral membranes in replication of human cytomegalovirus in polarized retinal pigment epithelial cells. J. Gen. Virol 1996, 77(Pt 1):61-74.
    • (1996) J. Gen. Virol , vol.77 , Issue.1 , pp. 61-74
    • Tugizov, S.1    Maidji, E.2    Pereira, L.3
  • 42
    • 23244466315 scopus 로고    scopus 로고
    • Human cytomegalovirus UL131 open reading frame is required for epithelial cell tropism
    • Wang D., Shenk T. Human cytomegalovirus UL131 open reading frame is required for epithelial cell tropism. J. Virol. 2005, 79:10330-10338.
    • (2005) J. Virol. , vol.79 , pp. 10330-10338
    • Wang, D.1    Shenk, T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.