Cell salvage of cardiotomy suction blood improves the balance between pro- and anti-inflammatory cytokines after cardiac surgery

European Journal of Cardio-thoracic Surgery

Volumn 44, Issue 3, 2013, Pages 506-511

  Gäbel, Jakob ^a   Westerberg, Martin ^a   Bengtsson, Anders ^a   Jeppsson, Anders ^a,b  

^a SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

Cardiotomy suction; Cell salvage; Cytokines; Extracorporeal circulation; Inflammation

Indexed keywords

CYTOKINE; INTERLEUKIN 10; INTERLEUKIN 4; INTERLEUKIN 6; INTERLEUKIN 7; INTERLEUKIN 8; INTERLEUKIN 9; INTERLEUKIN RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ARTICLE; BLOOD LEVEL; BLOOD TRANSFUSION; CLINICAL ARTICLE; CORONARY ARTERY BYPASS GRAFT; EXTRACORPOREAL CIRCULATION; FEMALE; HEART SURGERY; HUMAN; INFLAMMATION; MALE; PRIORITY JOURNAL; SUCTION; SYSTEMIC CIRCULATION;

CARDIOTOMY SUCTION; CELL SALVAGE; CYTOKINES; EXTRACORPOREAL CIRCULATION; INFLAMMATION;

AGED; CORONARY ARTERY BYPASS; CYTOKINES; FEMALE; HUMANS; MALE; OPERATIVE BLOOD SALVAGE; PROSPECTIVE STUDIES; SUCTION;

EID: 84882725617     PISSN: 10107940     EISSN: 1873734X     Source Type: Journal    
DOI: 10.1093/ejcts/ezt019     Document Type: Article

References (25)

1. Paparella D, Yau TM, Young E. Cardiopulmonary bypass induced inflammation: pathophysiology and treatment. An update. Eur J Cardiothorac Surg 2002;21:232-44.
2. Wan S, LeClerc JL, Vincent JL, DeSmet JM, Barvais L, Goldstein M. Inflammatory response to cardiopulmonary bypass: mechanisms involved and possible therapeutic strategies. Chest 1997;112:676-92.
3. Zahler S, Massoudy P, Hartl H, Hahnel C, Meisner H, Becker BF. Acute cardiac inflammatory response to postischemic reperfusion during cardiopulmonary bypass. Cardiovasc Res 1999;41:722-30.
4. Weis F, Beiras-Fernandez A, Schelling G, Briegel J, Lang P, Hauer D et al. Stress doses of hydrocortisone in high-risk patients undergoing cardiac surgery: effects on interleukin-6 to interleukin-10 ratio and early outcome. Crit Care Med 2009;37:1685-90.
5. Castellheim A, Hoel TN, Videm V, Fosse E, Pharo A, Svennevig J et al. Biomarker profile in off-pump and on-pump coronary artery bypass grafting surgery in low-risk patients. Ann Thorac Surg 2008;85:1994-2002.
6. Taniguchi T, Koido Y, Aiboshi J, Yamashita T, Suzaki S, Kurokawa A. Change in the ratio of interleukin-6 to interleukin-10 predicts a poor outcome in patients with systemic inflammatory response syndrome. Crit Care Med 1999;27:1262-4.
7. Taniguchi T, Koido Y, Aiboshi J, Yamashita T, Suzaki S, Kurokawa A. The ratio of interleukin-6 to interleukin-10 correlates with severity in patients with chest and abdominal trauma. Am J Emerg Med 1999;17:548-51.
8. Gasz G, Lenard L, Racz B, Benko L, Borsiczky B, Cserepes B et al. Effect of cardiopulmonary bypass on cytokine network and myocardial cytokine production. Clin Cardiol 2006;29:311-5.
9. Cholette JM, Henrichs KF, Alfieris GM, Powers KS, Phipps R, Spinelli SL et al. Washing red blood cells and platelets transfused in cardiac surgery reduces postoperative inflammation and number of transfusions: results of a prospective, randomized, controlled clinical trial. Pediatr Crit Care Med 2012;13:290-9.
10. Westerberg M, Bengtsson A, Jeppsson A. Coronary surgery without cardiotomy suction and autotransfusion reduces the postoperative systemic inflammatory response. Ann Thorac Surg 2004;78:54-9.
11. Aldea GS, Soltow LO, Chandler WL, Triggs CM, Vocelka CR, Crockett GI et al. Limitation of thrombin generation, platelet activation, and inflammation by elimination of cardiotomy suction in patients undergoing coronary artery bypass grafting treated with heparin-bonded circuits. J Thorac Cardiovasc Surg 2002;123:742-55.
12. Flom-Halvorsen H, Ovrum E, Tangen G, Brosstad F, Ringdal MA, Oystese R. Autotransfusion in coronary artery bypass grafting. J Thorac Cardiovasc Surg 1999;118:610-7.
13. Westerberg M, Gäbel J, Bengtsson A, Sellgren J, Eidem O, Jeppsson A. Hemodynamic effects of cardiotomy suction blood. J Thorac Cardiovasc Surg 2006;131:1352-7.
14. Damgaard S, Nielsen CH, Andersen LW, Bendtzen K, Tvede M, Steinbruächel DA. Cell saver for on-pump coronary operations reduces systemic inflammatory markers: a randomized trial. Ann Thorac Surg 2010;89:1511-7.
15. Allen J, McBride WT, McMurray TJ, Phillips AS, Prasad Penugonda S, Campalani G et al. Cell salvage alters the systemic inflammatory response after off-pump coronary artery bypass grafting surgery. Ann Thorac Surg 2007;83:578-85.
16. Gabay C, Lamacchia C, Palmer G. IL-1 pathways in inflammation and human diseases. Nat Rev Rheumatol 2010;6:232-41.
17. Cesari F, Caporale R, Marcucci R, Caciolli S, Stefano PL, Capalbo A et al. NTproBNP and the anti-inflammatory cytokines are correlated with endothelial progenitor cells' response to cardiac surgery. Atherosclerosis 2008;199:138-46.
18. Chen CC, Manning M. TGF-Bl, IL-10 and IL-4 differentially modulate the cytokine-induced expression of IL-6 and IL-8 in human endothelial cells. Cytokine 1996;8:58-65.
19. Das UN. Current advances in sepsis and septic shock with particular emphasis on the role of insulin. Med Sci Monit 2003;9:181-92.
20. Nathan N, Preux PM, Feiss P, Denizot Y. Plasma interleukin-4, interleukin-10, and interleukin-13 concentrations and complications after coronary artery bypass graft surgery. J Cardiothorac Vasc Anesth 2000;14: 156-60.
21. Kawamura T, Wakusawa R, Inada K. Interleukin-10 and interleukin-1 receptor antagonists increase during cardiac surgery. Can J Anaesth 1997; 44:38-42.
22. Markewitz A, Lante W, Franke A, Marohl K, Kuhlmann WD, Weinhold C. Alterations of cell-mediated immunity following cardiac operations: clinical implications and open questions. Shock 2001;16(Suppl):10-5.
23. Manukyan MC, Alvernaz CH, Poynter JA, Wang Y, Brewster BD, Weil BR et al. Interleukin-10 protects the ischemic heart from reperfusion injury via the STAT3 pathway. Surgery 2011;150:231-9.
24. Society of Thoracic Surgeons Blood Conservation Guideline Task Force 2011. Update to the Society of Thoracic Surgeons and the Society of Cardiovascular Anesthesiologists blood conservation clinical practice guidelines. Ann Thorac Surg 2011;91:944-82.
25. de Haan J, Boonstra PW, Monnink SH, Ebels T, van Oeveren W. Retransfusion of suctioned blood during cardiopulmonary bypass impairs hemostasis. Ann Thorac Surg 1995;59:901-7.