Effects of overfeeding naturally-mated adolescent ewes on maternal, fetal, and postnatal lamb growth

Journal of Animal Science

Volumn 90, Issue 11, 2012, Pages 3698-3708

  Peel, R K ^a   Eckerle, G J ^a   Anthony, R V ^a  

^a Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

Adolescent pregnancy; Intrauterine growth restriction; Nutrition; Postnatal growth; Sheep

Indexed keywords

MESSENGER RNA;

ANIMAL; ANIMAL DISEASE; ANIMAL FOOD; ANIMAL HUSBANDRY; ARTICLE; DIET; FEMALE; FETUS DEVELOPMENT; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; LIVER; MATERNAL NUTRITION; METABOLISM; PHYSIOLOGY; PREGNANCY; SHEEP;

ANIMAL FEED; ANIMAL HUSBANDRY; ANIMAL NUTRITIONAL PHYSIOLOGICAL PHENOMENA; ANIMALS; DIET; FEMALE; FETAL DEVELOPMENT; GENE EXPRESSION REGULATION; LIVER; MATERNAL NUTRITIONAL PHYSIOLOGICAL PHENOMENA; PREGNANCY; RNA, MESSENGER; SHEEP;

EID: 84882687180     PISSN: 00218812     EISSN: 15253163     Source Type: Journal    
DOI: 10.2527/jas.2012-5140     Document Type: Article

References (49)

1. Barbera, A., O. W. Jones, G. O. Zerbe, J. C. Hobbins, F. C. Battaglia, and G. Meschia. 1995. Early ultrasonographic detection of fetal growth retardation in an ovine model of placental insufficiency. Am. J. Obstet. Gynecol. 173:1071-1074.
2. Barker, D. J. P., and P. D. Gluckman. 1993. Fetal nutrition and cardiovascular disease in adult life. Lancet 341:938-941.
3. Blom, A. K., K. Hove, and J. J. Nedkvitne. 1976. Plasma insulin and growth hormone concentrations in pregnant sheep II: Postabsorptive levels in mid- and late pregnancy. Acta Endocrinol. 82:553-560.
4. Christenson, R. K., and R. L. Prior. 1976. Influence of dietary protein and energy on reproductive performance and nitrogen metabolism in Finn-cross ewes. J. Anim. Sci. 43:1104-1113.
5. Da Silva, P., R. P. Aitken, S. M. Rhind, P. A. Racey, and J. M. Wallace. 2001. Influence of placentally mediated fetal growth restriction on the onset of puberty in male and female lambs. Reproduction 122:375-383.
6. Erikson Hagen, A.S., R. J. Orbus, R. B. Wilkening, T. R. H. Regnault and R. V. Anthony. 2005. Placental expression of angiopoietin-1, angiopoietin-2 and Tie-2 during placental development in an ovine model of placental insufficiency-fetal growth restriction. Ped. Res. 58:1228-1232.
7. Ford, S. P., L. Zhang, M. Zhu, M. M. Miller, D. T. Smith, B. W. Hess, G. E. Moss, P. W. Nathanielsz, and M. J. Nijland. 2009. Maternal obesity accelerates fetal pancreatic ß-cell but not α-cell development in sheep: Prenatal consequences. Am. J. Physiol. Regul. Integr. Comp. Physiol. 297:R835-R843.
8. Gadd, T. W., R. P. Aitken, J. M. Wallace, and D. C. Wathes. 2000. Effect of a high maternal dietary intake during mid-gestation on components of the utero-placental insulin-like growth factor (IGF) system in adolescent sheep with retarded placental development. J. Reprod. Fertil. 118:407-416.
9. Galan, H. L., M. J. Hussey, A. Barbera, E. Ferrazzi, M. Chung, J. C. Hobbins, and F. C. Battaglia. 1999. Relationship of fetal growth to duration of heat stress in an ovine model of placental insufficiency. Am. J. Obstet. Gynecol. 180:1278-1282.
10. George, L. A., A. B. Uthlaut, N. M. Long, P. W. Nathanielsz, and S. P. Ford. 2010. Different levels of overnutrition and weight gain during pregnancy have differential effects on fetal growth and organ development. Reprod. Biol. Endocrinol. 8:75.
11. Godfredson, J. A., M. D. Holland, K. G. Odde, and K. L. Hossner. 1991. Hypertrophy and hyperplasia of bovine fetal tissues during development: fetal liver insulin-like growth factor I mRNA expression. J. Anim. Sci. 69:1074-1081.
12. Godfrey, K. M., and D. P. J. Barker. 2001. Fetal programming and adult health. Pub. Health Nutr. 4:611-624.
13. Hammer, C. J., K. A. Vonnahme, J. B. Taylor, D. A. Redmer, J. S. Luther, T. L. Neville, J. J. Reed, J. S. Caton, and L. P. Reynolds. 2007. Effects of maternal nutrition and selenium supplementation on absorption of IgG and survival of lambs. J. Anim. Sci. 85(Suppl. 1):391.
14. Hove K, and A. K. Blom. 1976. Plasma insulin and growth hormone concentrations in pregnant sheep I: Diurnal variations in midand late pregnancy. Acta Endocrinologica 82:544-552.
15. Kappes, S. M., W. C. Warren, S. L. Pratt, R. Liang and R. V. Anthony. 1992. Quantification and cellular localization of ovine placental lactogen messenger ribonucleic acid expression during mid- and late-gestation. Endocrinology 131:2829-2838.
16. Kenyon, P. R., H. T. Blair, C. M. C. Jenkinson, S. T. Morris, D. D. S. Mackenzie, S. W. Peterson, E. C. Firth, and P. L. Johnston. 2009. The effect of ewe size and nutritional regimen beginning in early pregnancy on ewe and lamb performance to weaning. New Zealand J. Agric. Res. 52:203-212.
17. Littell, R. C., P. R. Henry, and C. B. Ammerman. 1998. Statistical analysis of repeated measures data using SAS procedures. J. Anim. Sci. 76:1216-1231.
18. Long, N. M., L. A. George, D. T. Smith, P. W. Nathanielsz, and S. P. Ford. 2010. Maternal obesity and increased nutrient intake before and during gestation in the ewe results in altered growth, adiposity, and glucose tolerance in adult offspring. J. Anim. Sci. 88:3546-3553.
19. Matsuzaki, M., J. S. Milne, R. P. Aitken, D. A. Redmer, and J. M. Wallace. 2004. Overnourishing pregnant adolescent ewes stimulates perirenal fat deposition in their growth restricted foetuses. J. Anim. Feed. Sci. 13(Suppl. 1):519-522.
20. Meyer, A. M., J. J. Reed. T. L. Neville, J. B. Taylor, C. J. Hammer, L. P. Reynolds, D. A. Redmer, K. A. Vonnahme, and J. S. Caton. 2010. Effects of plane of nutrition and selenium supply during gestation on ewe and neonatal offspring performance, body composition, and serum selenium. J. Anim. Sci. 88:1786-1800.
21. NRC. 1985. Nutrient Requirements of Sheep. 6th rev. ed. Natl. Acad. Press, Washington, DC.
22. Quirke, J. F., and J. P. Hanrahan. 1983. Comparison of the survival of fertilized eggs from adult ewes in the uteri of adult ewes and ewe lambs. J. Reprod. Fertil. 68:289-294.
23. Regnault, T. R., H. V. Oddy, C. Nancarrow, N. Sriskandarajah, and R. J. Scaramuzzi. 2004. Glucose-stimulated insulin response in pregnant sheep following acute suppression of plasma non-esterified fatty acid concentrations. Reprod Biol. Endocrinol. 7:64.
24. Reimers, T. J., R. G. Cowan, J. P. McCann, and M. W. Ross. 1982. Validation of a rapid solid-phase radioimmunoassay for canine, bovine, and equine insulin. Am. J. Vet. Res. 43:1274-1278.
25. Rhoads, R. P., P. L. Greenwood, A. W. Bell, and Y. R. Boisclair. 2000. Nutritional regulation of the genes encoding the acid-labile subunit and other components of the circulating insulin-like growth factor system in the sheep. J. Anim. Sci. 78:2681-2689.
26. Rosenfeld, C. S., and R. M. Roberts. 2004. Maternal diet and other factors affecting offspring sex ratio: A review. Biol. Reprod. 71:1063-1070.
27. Russel, A. J. F., J. M. Doney, and R. G. Gunn. 1969. Subjective assessment of body fat in live sheep. J. Agric. Sci. 72:451-454.
28. Sinclair, K. D., T. G. McEvoy, E. K. Maxfield, C. A. Maltin, L. E. Young, I. Wilmut, P. J. Broadbent, and J. J. Robinson. 1999. Aberrant fetal growth and development after in vitro culture of sheep zygotes. J. Reprod. Fertil. 116:177-186.
29. Sjögren, K., J.-L. Liu, K. Blad, S. Skrtic, O. Vidal, V. Wallenius, D. LeRoith, J. Törnell, O. G. P. Isaksson, J.-O. Jansson, and C. Ohlsson. 1999. Liver-derived insulin-like growth factor I (IGF-I) is the principal source of IGF-I in blood but is not required for postnatal body growth in mice. Proc. Natl. Acad. Sci. 96:7088-7092.
30. Swanson, T. J., C. J. Hammer, J. S. Luther, D. B. Carlson, J. B. Taylor, D. A. Redmer, T. L. Neville, J. J. Reed, L. P. Reynolds, J. S. Caton, and K. A. Vonnahme. 2008. Effects of gestational plane of nutrition and selenium supplementation on mammary development and colostrum quality in pregnant ewe lambs. J. Anim. Sci. 86:2415-2423.
31. Tong, J., M. J. Zhu, K. R. Underwood, B. W. Hess, S. P. Ford, and M. Du. 2008. AMP-activated protein kinase and adipogenesis in sheep fetal skeletal muscle and 3T3-L1 cells. J. Anim. Sci. 86:1296-1305
32. Tong, J. F., X. Yan, M. J. Zhu, S. P. Ford, P. W. Nathanielsz, and M. Du. 2009. Maternal obesity downregulatesmyogenesis and ß-catenin signaling in fetal skeletal muscle. Am. J. Physiol. Endocrinol. Metab. 296:E917-E924.
33. Wallace, J. M. 2000. Nutrient partitioning during pregnancy: adverse gestational outcome in overnourished adolescent dams. Proc. Nutr. Soc. 59:107-117.
34. Wallace, J. M., R. P. Aitken, and M. A. Cheyne. 1996. Nutrient partitioning and fetal growth in rapidly growing adolescent ewes. J. Reprod. Fertil. 107:183-190.
35. Wallace, J. M., D. A. Bourke, R. P. Aitken, and M. A. Cruickshank. 1999. Switching maternal dietary intake at the end of the first trimester has profound effects on placental development and fetal growth in adolescent ewes carrying singleton fetuses. Biol. Reprod. 61:101-110.
36. Wallace, J. M., D. A. Bourke, R. P. Aitken, N. Leitch, and W. W. Hay, Jr. 2002. Blood flows and nutrient uptakes in growth-restricted pregnancies induced by overnourishing adolescent sheep. Am. J. Physiol. Regul. Integr. Comp. Physiol. 282:R1027-R1036.
37. Wallace, J. M., D. A. Bourke, R. P. Aitken, R. M. Palmer, P. Da Silva, and M. A. Cruickshank. 2000. Relationship between nutritionally- mediated placental growth restriction and fetal growth, body composition and endocrine status during late gestation in adolescent sheep. Placenta 21:100-108.
38. Wallace, J. M., D. A. Bourke, P. Da Silva, and R. P. Aitken. 2003. Influence of progesterone supplementation during the first third of pregnancy on fetal and placental growth in overnourished adolescent ewes. Reproduction 126:481-487.
39. Wallace, J. M., P. Da Silva, R. P. Aitken, and M. A. Cruickshank. 1997. Maternal endocrine status in relation to pregnancy outcome in rapidly growing adolescent sheep. J. Endocrinology 155:359-368.
40. Wallace, J. M., J. S. Milne, and R. P. Aitken. 2004. Maternal growth hormone treatment from day 35 to 80 of gestation alters nutrient partitioning in favor of uteroplacental growth in the overnourished adolescent sheep. Biol. Reprod. 70:1277-1285.
41. Wallace, J. M., J. S. Milne, and R. P. Aitken. 2005. The effect of overnourishing singleton-bearing adult ewes on nutrient partitioning to the gravid uterus. Brit. J. Nutr. 94:533-539.
42. Wallace, J. M., J. S. Milne, and R. P. Aitken. 2010. Effect of weight and adiposity at conception and wide variations in gestational dietary intake on pregnancy outcome and early postnatal performance in young adolescent sheep. Biol. Reprod. 82:320-330.
43. Wallace, J. M., J. S. Milne, R. P. Aitken, and W. W. Hay, Jr. 2007. Sensitivity to metabolic signals in late-gestation growth-restricted fetuses from rapidly growing adolescent sheep. Am. J. Physiol. Endocrinol. Metab. 293:E1233-E1241.
44. Wallace, J. M., J. S. Milne, M. Matsuzaki, and R. P. Aitken. 2008. Serial measurement of uterine blood fl ow from mid to late gestation in growth restricted pregnancies induced by overnourishing adolescent sheep dams. Placenta 29:718?724.
45. Warren, W. C., R. Liang, G. G. Krivi, N. R. Siegel and R. V. Anthony. 1990. Purifi cation and structural characterization of ovine placental lactogen. J. Endocrinol. 126:141?149.
46. Wright, C. D., R. J. Orbus, T.R.H. Regnault, and R. V. Anthony. 2008. Effects of early gestation GH administration on placental and fetal development in sheep. J. Endocrinology 198:91?99.
47. Wu, G., F. W. Bazer, J. M. Wallace, and T. E. Spencer. 2006. Boardinvited review: Intrauterine growth retardation: Implications for the animal sciences. J. Anim. Sci. 84:2316?2337.
48. Yan, X., Y. Huang, J. X. Zhao, N. M. Long, A. B. Uthlaut, M. J. Zhu, S. P. Ford, P. W. Nathanielsz, and M. Du. 2011. Maternal obesityimpaired insulin signaling in sheep and induced lipid accumulation and fi brosis in skeletal muscle of offspring. Biol. Reprod. 85:172-178.
49. Zhang, L., S. P. Ford, and P. W. Nathanielsz. 2010. Maternal obesity (MO) increases fetal pancreatic ß-cell mitotic rate and the IGF-1, ERK signaling pathway at mid-gestation in the sheep. Reprod. Sci. 17(Suppl. 3):294A.