Management of type 1 diabetes mellitus using in vitro autologous adipose tissue trans-differentiated insulin-making cells

BMJ Case Reports

Volumn , Issue , 2013, Pages

  Dave, Shruti D ^a   Trivedi, Hargovind L ^a   Chooramani, Saroj G ^b   Chandra, Tulika ^c  

^a Institute of Kidney Diseases and Research Centre IKDRC   (India)

^b BANARAS HINDU UNIVERSITY   (India)

^c KING GEORGE'S MEDICAL UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

BORTEZOMIB; INSULIN; METHYLPREDNISOLONE;

ADIPOSE TISSUE CELL; ADOLESCENT; ADULT; ARTICLE; AUTOLOGOUS STEM CELL TRANSPLANTATION; BULIMIA; CASE REPORT; CELL DIFFERENTIATION; CLINICAL FEATURE; FATIGUE; FOLLOW UP; HEMATOPOIETIC STEM CELL; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; LEG PAIN; MALE; MESENCHYMAL STEM CELL; MICTURITION; PARESTHESIA; POLYDIPSIA; POLYURIA; PRIORITY JOURNAL; TREATMENT OUTCOME; WEAKNESS;

EID: 84882681975     PISSN: None     EISSN: 1757790X     Source Type: Journal    
DOI: 10.1136/bcr-2013-200226     Document Type: Article

References (5)

1. Trivedi HL, Vanikar AV, Thakker U, et al. Human adipose tissue-derived mesenchymal stem cells combined with hematopoietic stem cell transplantation synthesize insulin. Transplant Proc 2008;40:1135-39.
2. Van Belle TL, Coppieters KT, Von Herrath MG. Type 1 diabetes: etiology, immunology and therapeutic strategies. Physiol Rev 2011;91:79-118.
3. Picinich SC, Mishra PJ, Glod J, et al. The therapeutic potential of mesenchymal stem cells. Cell- & tissue-based therapy. Expert Opin Biol Ther 2007;7:965.
4. Lee RH, Seo MJ, Reger RL, et al. Multipotent stromal cells from human marrow home to and promote repair of pancreatic islets and renal glomeruli in diabetic NOD/scid mice. Proc Natl Acad Sci USA 2006;103:17438.
5. Chen LB, Jiang XB, Yang L. Differentiation of rat marrow mesenchymal stem cells into pancreatic islet beta-cells. World J Gastroenterol 2004;10:3016-20.