-
1
-
-
80051804871
-
Rare phenomenon: Liver metastases from glioblastoma multiforme
-
Schonsteiner SS, Bommer M, Haenle MM, Klaus B, Scheuerle A, Schmid M, et al. Rare phenomenon: liver metastases from glioblastoma multiforme. J Clin Oncol 2011;29:e668-71.
-
(2011)
J Clin Oncol
, vol.29
-
-
Schonsteiner, S.S.1
Bommer, M.2
Haenle, M.M.3
Klaus, B.4
Scheuerle, A.5
Schmid, M.6
-
2
-
-
0038179723
-
Cost of migration: Invasion of malignant gliomas and implications for treatment
-
Giese A, Bjerkvig R, Berens ME, Westphal M. Cost of migration: invasion of malignant gliomas and implications for treatment. J Clin Oncol 2003;21:1624-36.
-
(2003)
J Clin Oncol
, vol.21
, pp. 1624-1636
-
-
Giese, A.1
Bjerkvig, R.2
Berens, M.E.3
Westphal, M.4
-
3
-
-
33846205171
-
A Ras inhibitor tilts the balance between Rac and Rho and blocks phosphatidylinositol 3-kinase-dependent glioblastoma cell migration
-
Goldberg L, Kloog Y. A Ras inhibitor tilts the balance between Rac and Rho and blocks phosphatidylinositol 3-kinase-dependent glioblastoma cell migration. Cancer Res 2006;66:11709-17.
-
(2006)
Cancer Res
, vol.66
, pp. 11709-11717
-
-
Goldberg, L.1
Kloog, Y.2
-
4
-
-
84055191095
-
Activation of Rac1 by Src-dependent phosphorylation of Dock180(Y1811) mediates PDGFRalpha-stimulated glioma tumorigenesis in mice and humans
-
Feng H, Hu B, Liu KW, Li Y, Lu X, Cheng T, et al. Activation of Rac1 by Src-dependent phosphorylation of Dock180(Y1811) mediates PDGFRalpha-stimulated glioma tumorigenesis in mice and humans. J Clin Invest 2011;121:4670-84.
-
(2011)
J Clin Invest
, vol.121
, pp. 4670-4684
-
-
Feng, H.1
Hu, B.2
Liu, K.W.3
Li, Y.4
Lu, X.5
Cheng, T.6
-
5
-
-
48249125791
-
Malignant gliomas in adults
-
Wen PY, Kesari S. Malignant gliomas in adults. N Engl J Med 2008; 359:492-507.
-
(2008)
N Engl J Med
, vol.359
, pp. 492-507
-
-
Wen, P.Y.1
Kesari, S.2
-
6
-
-
33644820339
-
Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis
-
Phillips HS, Kharbanda S, Chen R, Forrest WF, Soriano RH, Wu TD, et al. Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis. Cancer Cell 2006;9:157-73.
-
(2006)
Cancer Cell
, vol.9
, pp. 157-173
-
-
Phillips, H.S.1
Kharbanda, S.2
Chen, R.3
Forrest, W.F.4
Soriano, R.H.5
Wu, T.D.6
-
7
-
-
73649123907
-
Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1
-
Verhaak RGW, Hoadley KA, Purdom E, Wang V, Qi Y, Wilkerson MD, et al. Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell 2010;17:98-110.
-
(2010)
Cancer Cell
, vol.17
, pp. 98-110
-
-
Rgw, V.1
Hoadley, K.A.2
Purdom, E.3
Wang, V.4
Qi, Y.5
Wilkerson, M.D.6
-
8
-
-
84867606428
-
Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma
-
Sturm D, Witt H, Hovestadt V, Khuong-Quang D-A, Jones DTW, Konermann C, et al. Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma. Cancer Cell 2012;22:425-37.
-
(2012)
Cancer Cell
, vol.22
, pp. 425-437
-
-
Sturm, D.1
Witt, H.2
Hovestadt, V.3
Khuong-Quang, D.-A.4
Dtw, J.5
Konermann, C.6
-
9
-
-
79957905986
-
Molecular subclassification of diffuse gliomas: Seeing order in the chaos
-
Huse JT, Phillips HS, Brennan CW. Molecular subclassification of diffuse gliomas: seeing order in the chaos. Glia 2011;59:1190-9.
-
(2011)
Glia
, vol.59
, pp. 1190-1199
-
-
Huse, J.T.1
Phillips, H.S.2
Brennan, C.W.3
-
10
-
-
4644313275
-
Gene expression profiling of gliomas strongly predicts survival
-
Freije WA, Castro-Vargas FE, Fang Z, Horvath S, Cloughesy T, Liau LM, et al. Gene expression profiling of gliomas strongly predicts survival. Cancer Res 2004;64:6503-10.
-
(2004)
Cancer Res
, vol.64
, pp. 6503-6510
-
-
Freije, W.A.1
Castro-Vargas, F.E.2
Fang, Z.3
Horvath, S.4
Cloughesy, T.5
Liau, L.M.6
-
11
-
-
77954596239
-
Integratedmoleculargeneticprofilingofpediatrichigh- gradegliomasreveals key differences with the adult disease
-
PaughBS,QuC,Jones C, LiuZ,Adamowicz-BriceM,ZhangJ, et al. Integratedmoleculargeneticprofilingofpediatrichigh- gradegliomasreveals key differences with the adult disease. J Clin Oncol 2010;28:3061-8.
-
(2010)
J Clin Oncol
, vol.28
, pp. 3061-3068
-
-
Paugh, B.S.1
Qu, C.2
Jones, C.3
Liu, Z.4
Adamowicz-Brice, M.5
Zhang, J.6
-
12
-
-
75149195336
-
The transcriptional network for mesenchymal transformation of brain tumours
-
Carro MS, Lim WK, Alvarez MJ, Bollo RJ, Zhao X, Snyder EY, et al. The transcriptional network for mesenchymal transformation of brain tumours. Nature 2010;463:318-25.
-
(2010)
Nature
, vol.463
, pp. 318-325
-
-
Carro, M.S.1
Lim, W.K.2
Alvarez, M.J.3
Bollo, R.J.4
Zhao, X.5
Snyder, E.Y.6
-
13
-
-
84255160601
-
The transcriptional coactivator TAZ regulates mesenchymal differentiation in malignant glioma
-
Bhat KP, Salazar KL, Balasubramaniyan V, Wani K, Heathcock L, Hollingsworth F, et al. The transcriptional coactivator TAZ regulates mesenchymal differentiation in malignant glioma. Genes Dev 2011;25: 2594-609.
-
(2011)
Genes Dev
, vol.25
, pp. 2594-2609
-
-
Bhat, K.P.1
Salazar, K.L.2
Balasubramaniyan, V.3
Wani, K.4
Heathcock, L.5
Hollingsworth, F.6
-
14
-
-
22044443282
-
Expression profile of an operationally-defined neural stem cell clone
-
Parker MA, Anderson JK, Corliss DA, Abraria VE, Sidman RL, Park KI, et al. Expression profile of an operationally-defined neural stem cell clone. Exp Neurol 2005;194:320-32.
-
(2005)
Exp Neurol
, vol.194
, pp. 320-332
-
-
Parker, M.A.1
Anderson, J.K.2
Corliss, D.A.3
Abraria, V.E.4
Sidman, R.L.5
Park, K.I.6
-
15
-
-
44649201561
-
The HECT-domain ubiquitin ligase Huwe1 controls neural differentiation and proliferation by destabilizing the N-Myc oncoprotein
-
Zhao X, Heng JI, Guardavaccaro D, Jiang R, Pagano M, Guillemot F, et al. The HECT-domain ubiquitin ligase Huwe1 controls neural differentiation and proliferation by destabilizing the N-Myc oncoprotein. Nat Cell Biol 2008;10:643-53.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 643-653
-
-
Zhao, X.1
Heng, J.I.2
Guardavaccaro, D.3
Jiang, R.4
Pagano, M.5
Guillemot, F.6
-
16
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
-
Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001;25:402-8.
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
17
-
-
46249088370
-
Lumi: A pipeline for processing Illumina microarray
-
Du P, Kibbe WA, Lin SM. lumi: a pipeline for processing Illumina microarray. Bioinformatics 2008;24:1547-8.
-
(2008)
Bioinformatics
, vol.24
, pp. 1547-1548
-
-
Du, P.1
Kibbe, W.A.2
Lin, S.M.3
-
18
-
-
79952092706
-
Phase II study of the antibody drug conjugate trastuzumab-DM1 for the treatment of human epidermal growth factor receptor 2 (HER2)- positive breast cancer after prior HER2-directed therapy
-
Burris HA III, Rugo HS, Vukelja SJ, Vogel CL, Borson RA, Limentani S, et al. Phase II study of the antibody drug conjugate trastuzumab-DM1 for the treatment of human epidermal growth factor receptor 2 (HER2)- positive breast cancer after prior HER2-directed therapy. J Clin Oncol 2011;29:398-405.
-
(2011)
J Clin Oncol
, vol.29
, pp. 398-405
-
-
Burris Iii., H.A.1
Rugo, H.S.2
Vukelja, S.J.3
Vogel, C.L.4
Borson, R.A.5
Limentani, S.6
-
19
-
-
77956030786
-
Inhibition of mutated, activated BRAF in metastatic melanoma
-
Flaherty KT, Puzanov I, Kim KB, Ribas A, McArthur GA, Sosman JA, et al. Inhibition of mutated, activated BRAF in metastatic melanoma. N Engl J Med 2010;363:809-19.
-
(2010)
N Engl J Med
, vol.363
, pp. 809-819
-
-
Flaherty, K.T.1
Puzanov, I.2
Kim, K.B.3
Ribas, A.4
McArthur, G.A.5
Sosman, J.A.6
-
20
-
-
78649976005
-
An integrated approach to uncover drivers of cancer
-
Akavia UD, Litvin O, Kim J, Sanchez-Garcia F, Kotliar D, Causton HC, et al. An integrated approach to uncover drivers of cancer. Cell 2010;143:1005-17.
-
(2010)
Cell
, vol.143
, pp. 1005-1017
-
-
Akavia, U.D.1
Litvin, O.2
Kim, J.3
Sanchez-Garcia, F.4
Kotliar, D.5
Causton, H.C.6
-
21
-
-
54549108740
-
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
-
Cancer genome atlas research network
-
Cancer Genome Atlas Research Network. Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 2008;455:1061-8.
-
(2008)
Nature
, vol.455
, pp. 1061-1068
-
-
-
22
-
-
33645127077
-
Genetic regulators of large-scale transcriptional signatures in cancer
-
Adler AS, Lin M, Horlings H, Nuyten DS, van de Vijver MJ, Chang HY. Genetic regulators of large-scale transcriptional signatures in cancer. Nat Genet 2006;38:421-30.
-
(2006)
Nat Genet
, vol.38
, pp. 421-430
-
-
Adler, A.S.1
Lin, M.2
Horlings, H.3
Nuyten, D.S.4
Van De Vijver, M.J.5
Chang, H.Y.6
-
24
-
-
0037113916
-
The RhoAbinding protein, rhophilin-2, regulates actin cytoskeleton organization
-
Peck JW, Oberst M, Bouker KB, Bowden E, Burbelo PD. The RhoAbinding protein, rhophilin-2, regulates actin cytoskeleton organization. J Biol Chem 2002;277:43924-32.
-
(2002)
J Biol Chem
, vol.277
, pp. 43924-43932
-
-
Peck, J.W.1
Oberst, M.2
Bouker, K.B.3
Bowden, E.4
Burbelo, P.D.5
-
25
-
-
0035475321
-
Paxillin: A focal adhesion-associated adaptor protein
-
Schaller MD. Paxillin: a focal adhesion-associated adaptor protein. Oncogene 2001;20:6459-72.
-
(2001)
Oncogene
, vol.20
, pp. 6459-6472
-
-
Schaller, M.D.1
-
26
-
-
0035171699
-
Cofilin phosphorylation by protein kinase testicular protein kinase 1 and its role in integrin-mediated actin reorganization and focal adhesion formation
-
Toshima J, Toshima JY, Amano T, Yang N, Narumiya S, Mizuno K. Cofilin phosphorylation by protein kinase testicular protein kinase 1 and its role in integrin-mediated actin reorganization and focal adhesion formation. Mol Biol Cell 2001;12:1131-45.
-
(2001)
Mol Biol Cell
, vol.12
, pp. 1131-1145
-
-
Toshima, J.1
Toshima, J.Y.2
Amano, T.3
Yang, N.4
Narumiya, S.5
Mizuno, K.6
-
27
-
-
79955562657
-
Network modeling of the transcriptional effects of copy number aberrations in glioblastoma
-
Jornsten R, Abenius T, Kling T, Schmidt L, Johansson E, Nordling TE, et al. Network modeling of the transcriptional effects of copy number aberrations in glioblastoma. Mol Syst Biol 2011;7:486.
-
(2011)
Mol Syst Biol
, vol.7
, pp. 486
-
-
Jornsten, R.1
Abenius, T.2
Kling, T.3
Schmidt, L.4
Johansson, E.5
Nordling, T.E.6
-
28
-
-
84862827172
-
Genome-wide functional annotation of dual-specificity protein- and lipid-binding modules that regulate protein interactions
-
Chen Y, Sheng R, Kallberg M, Silkov A, Tun MP, Bhardwaj N, et al. Genome-wide functional annotation of dual-specificity protein- and lipid-binding modules that regulate protein interactions. Mol Cell 2012;46:226-37.
-
(2012)
Mol Cell
, vol.46
, pp. 226-237
-
-
Chen, Y.1
Sheng, R.2
Kallberg, M.3
Silkov, A.4
Tun, M.P.5
Bhardwaj, N.6
-
29
-
-
34249748178
-
Rhophilin-2 is targeted to late-endosomal structures of the vesicular machinery in the presence of activated RhoB
-
Steuve S, Devosse T, Lauwers E, Vanderwinden JM, Andre B, Courtoy PJ, et al. Rhophilin-2 is targeted to late-endosomal structures of the vesicular machinery in the presence of activated RhoB. Exp Cell Res 2006;312:3981-9.
-
(2006)
Exp Cell Res
, vol.312
, pp. 3981-3989
-
-
Steuve, S.1
Devosse, T.2
Lauwers, E.3
Vanderwinden, J.M.4
Andre, B.5
Courtoy, P.J.6
-
30
-
-
56349121125
-
An oncogenomics-based in vivo RNAi screen identifies tumor suppressors in liver cancer
-
Zender L, Xue W, Zuber J, Semighini CP, Krasnitz A, Ma B, et al. An oncogenomics-based in vivo RNAi screen identifies tumor suppressors in liver cancer. Cell 2008;135:852-64.
-
(2008)
Cell
, vol.135
, pp. 852-864
-
-
Zender, L.1
Xue, W.2
Zuber, J.3
Semighini, C.P.4
Krasnitz, A.5
Ma, B.6
-
31
-
-
44449178868
-
Rho GTPases in cancer cell biology
-
Vega FM, Ridley AJ. Rho GTPases in cancer cell biology. FEBS Lett 2008;582:2093-101.
-
(2008)
FEBS Lett
, vol.582
, pp. 2093-2101
-
-
Vega, F.M.1
Ridley, A.J.2
-
32
-
-
84864049598
-
Rho GTPases in primary brain tumor malignancy and invasion
-
Khalil BD, El-Sibai M. Rho GTPases in primary brain tumor malignancy and invasion. J Neurooncol 2012;108:333-9.
-
(2012)
J Neurooncol
, vol.108
, pp. 333-339
-
-
Khalil, B.D.1
El-Sibai, M.2
|