Synthesis and SAR studies of marine natural products ma'edamines A, B and their analogues

Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 18, 2013, Pages 5135-5139

  Saha, Sanjay ^a,b   Reddy, Ch Venkata Ramana ^b   Xu, Shili ^c   Sankar, Saranya ^c   Neamati, Nouri ^c   Patro, Balaram ^a  

^a GVK BIOSCIENCES PVT LTD   (India)

^b JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY   (India)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Anticancer; Antiproliferative activity; Breast cancer; HER2; Marine natural products

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; ETHYLENEDIAMINE; HORMONE RECEPTOR; LAPATINIB; MED 111; MED 115; MED 117; MED 119; MED 120; MED 124; MED 128; MED 131; NATURAL PRODUCT; UNCLASSIFIED DRUG;

ANTIPROLIFERATIVE ACTIVITY; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG SYNTHESIS; IC 50; STRUCTURE ACTIVITY RELATION;

ANTICANCER; ANTIPROLIFERATIVE ACTIVITY; BREAST CANCER; HER2; MARINE NATURAL PRODUCTS;

ANTINEOPLASTIC AGENTS; BIOLOGICAL PRODUCTS; CELL LINE, TUMOR; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MOLECULAR STRUCTURE; PYRAZINES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84882646971     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2013.07.017     Document Type: Article

References (14)

1. Y. Liu J. Mar. Sci. Res. Dev. 2012 10.4172/2155-9910.1000e106
2. J.K. Jimenez, M. Šturdíková, and M. Šturdíka Acta Chim. Slovaca 2 2009 63
3. S. Sagar, M. Kaur, and K.P. Minneman Mar. Drugs 8 2010 2619
4. E. Fattorusso, and O. Taglialatela-Scafati Mar. Drugs 7 2009 130
5. K. Hirano, T. Kubota, M. Tsuda, K. Watanabe, J. Fromont, and J. Kobayashi Tetrahedron 56 2000 8107
6. S. Saha, V.R. Reddy, T. Chiranjeevi, U. Addepally, T.S. Chinta Rao, and B. Patro Bioorg. Med. Chem. Lett. 23 2013 1013
7. M.E. Jung, and J.C. Rohloff J. Org. Chem. 50 1985 4909
8. Kissman, H. M.; Nannet, N. Y.; Joseph, J. P.; Baker, B. R. US 2833810, 1956.
9. M. Delépine Bull. Soc. Chim. Fr. 13 1895 352
10. S.B. Patwari, M.A. Baseer, Y.B. Vibhute, and S.R. Bhusare Tetrahedron Lett. 44 2003 4893
11. Hansen, T. M.; Xin, Z.; et al., Theinopyridones as AMPK activators for the treatment of diabetes & obesity, US2005/38068A1, 2005.
12. T. Mossman J. Immunol. Methods 65 1983 55
13. S. Xu, F. Grande, A. Garofalo, and N. Neamati Mol. Cancer Ther. 12 2013 937
14. R.M. Neve Cancer Cell 10 2006 515