Enhancing production of prodigiosin from Serratia marcescens C3 by statistical experimental design and porous carrier addition strategy

Biochemical Engineering Journal

Volumn 78, Issue , 2013, Pages 93-100

  Chen, Wei Chuan ^a,h,i   Yu, Wan Ju ^b   Chang, Chia Che ^c,d   Chang, Jo Shu ^b   Huang, Shih Horng ^e,f   Chang, Chih Hung ^a,e   Chen, Shan Yu ^a   Chien, Chih Ching ^a   Yao, Chao Ling ^a   Chen, Wen Ming ^g   Wei, Yu Hong ^a  

^a YUAN ZE UNIVERSITY   (Taiwan)

^b NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^c NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^d CHINA MEDICAL UNIVERSITY   (Taiwan)

^e FAR EASTERN MEMORIAL HOSPITAL   (Taiwan)

^f TAIPEI CITY HOSPITAL   (Taiwan)

^g NATIONAL KAOHSIUNG UNIVERSITY OF APPLIED SCIENCES   (Taiwan)

^h CHANG GUNG UNIVERSITY   (Taiwan)

ⁱ TAIPEI MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Antibiotic; Fermentation; Immobilization; Microbial growth; Prodigiosin

Indexed keywords

APOPTOTIC EFFECTS; CALCIUM ALGINATE BEADS; CARBON AND NITROGEN; MICROBIAL GROWTH; OPTIMAL CONCENTRATION; PRODIGIOSIN; SERRATIA MARCESCENS; STATISTICAL EXPERIMENTAL DESIGN;

ANTIBIOTICS; FERMENTATION; OPTIMIZATION; RADIOACTIVE WASTE VITRIFICATION;

STATISTICS;

CARBON; NITROGEN; PRODIGIOSIN;

ARTICLE; CARBON SOURCE; CELL GROWTH; CELL PROLIFERATION; CHEMICAL STRUCTURE; DRUG MANUFACTURE; ENZYME RELEASE; EXPERIMENTAL DESIGN; IMMOBILIZED CELL; MICROBIAL GROWTH; MOLECULAR WEIGHT; NITROGEN CONCENTRATION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; QUORUM SENSING; RESPONSE SURFACE METHOD; SERRATIA MARCESCENS;

SERRATIA MARCESCENS;

EID: 84882633720     PISSN: 1369703X     EISSN: 1873295X     Source Type: Journal    
DOI: 10.1016/j.bej.2013.02.001     Document Type: Article

References (21)

1. Chang C.C., Chen W.C., Ho T.F., Wu H.S., Wei Y.H. Development of natural anti-tumor drugs by microorganisms. J. Biosci. Bioeng. 2011, 111:501-511.
2. Huh J.E., Yim J.H., Lee H.K., Moon E.Y., Rhee D.K., Pyo S. Prodigiosin isolated from Hahella chejuensis suppresses lipopolysaccharide-induced NO production by inhibiting p38 MAPK, JNK and NF-kappaB activation in murine peritoneal macrophages. Int. Immunopharmacol. 2007, 7:1825-1833.
3. Kawasaki T., Sakurai F., Hayakawa Y. A prodigiosin from the roseophilin producer Streptomyces griseoviridis. J. Nat. Prod. 2008, 71:1265-1267.
4. Furstner A. Chemistry and biology of roseophilin and the prodigiosin alkaloids: a survey of the last 2500 years. Angew. Chem. Int. Ed. Engl. 2003, 42:3582-3603.
5. Bennett J.W., Bentley R. Seeing red: the story of prodigiosin. Adv. Appl. Microbiol. 2000, 47:1-32.
6. Montaner B., Pérez-Tomás R. The cytotoxic prodigiosin induces phosphorylation of p38-MAPK but not of SAPK/JNK. Toxicol. Lett. 2002, 129:93-98.
7. Zhang J., Shen Y., Liu J., Wei D. Antimetastatic effect of prodigiosin through inhibition of tumor invasion. Biochem. Pharmacol. 2005, 69:407-414.
8. Ramoneda B.M., Pérez-Tomás R. Activation of protein kinase C for protection of cells against apoptosis induced by the immunosuppressor prodigiosin. Biochem. Pharmacol. 2002, 63:463-469.
9. Kim S.J., Lee H.K., Yim J.H. Statistical optimization of medium components for the production of prodigiosin by Hahella chejuensis KCTC 2396. J. Microbiol. Biotechnol. 2008, 18:1903-1907.
10. Kim S.J., Lee H.K., Yim J.H. Mutant selection of Hahella chejuensis KCTC 2396 and statistical optimization of medium components for prodigiosin yield-up. J. Microbiol. 2008, 46:183-188.
11. Wei Y.H., Chen W.C. Enhanced production of prodigiosin-like pigment from Serratia marcescens SM(R by medium improvement and oil-supplementation strategies. J. Biosci. Bioeng. 2005, 99:616-622.
12. Yamashita M., Nakagawa Y., Li H., Matsuyama T. Silica gel-dependent production of prodigiosin and serrawettins by Serratia marcescens in a liquid culture. Microbiol. Environ. 2001, 16:250-254.
13. Syzdek L.D. Influence of Serratia marcescens pigmentation on cell concentrations in aerosols produced by bursting bubbles. Appl. Environ. Microbiol. 1985, 4:173-178.
14. Wei Y.H., Yu W.J., Chen W.C. Enhanced undecylprodigiosin production from Serratia marcescens SS-1 by medium formulation and amino-acid supplementation. J. Biosci. Bioeng. 2005, 100:466-471.
15. Wei Y.H., Cheng C.L., Chien C.C., Wan H.M. Enhanced di-rhamnolipid production with an indigenous isolate Pseudomonas aeruginosa J16. Process Biochem. 2008, 43:769-774.
16. Giri A.V., Anandkumar N., Muthukumaran G., Pennathur G. A novel medium for the enhanced cell growth and production of prodigiosin from Serratia marcescens isolated from soil. BMC Microbiol. 2004, 4:1-10.
17. Clements-Jewery S. The reversal of glucose repressed prodigiosin production in Serratia marcescens by the cyclic 3'5'-adenosine monophosphate inhibitor theophylline. Experientia. 1976, 32:421-422.
18. Wei Y.H., Chen W.C., Huang C.K., Wu H.S., Sun Y.M., Lo C.W., Janarthanan O.M. Screening and evaluation of polyhydroxybutyrate-producing strains from indigenous isolate Cupriavidus taiwanensis strains. Int. J. Mol. Sci. 2011, 12:252-265.
19. Fonseca R., Silva A., De França F., Cardoso V., Sérvulo E. Optimizing carbon/nitrogen ratio for biosurfactant production by a Bacillus subtilis strain. Appl. Biochem. Biotechnol. 2007, 137-140(137):471-480.
20. Egli T., Zinn M. The concept of multiple-nutrient-limited growth of microorganisms and its application in biotechnological processes. Biotechnol. Adv. 2003, 22:35-43.
21. van Houdt R., Moons P., Jansen A., Vanoirbeek K., Michiels C.W. Isolation and functional analysis of luxS in Serratia plymuthica RVH1. FEMS Microbiol. Lett. 2006, 262:201-209.