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Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 18, 2013, Pages 5192-5194

A new strategy for the synthesis of crucigasterin A, and cytotoxic activity of this compound and its related analogues

(5) Kumar, Jayprakash Narayan a Reddy, Parigi Raghavendar a Das, Biswanath a Kumar, C Ganesh a Sujitha, Pombala a

a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY (India)

Author keywords

Chelation controlled; Crucigasterin A; Cytotoxicity; Grignard addition; Julia olefination; Total synthesis

Indexed keywords

ANTINEOPLASTIC AGENT; CRUCIGASTERIN A; MALIC ACID; NATURAL PRODUCT; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; ASCIDIACEA; BIRCH REDUCTION; BREAST ADENOCARCINOMA; CANCER CELL CULTURE; CHELATION; CONTROLLED STUDY; DRUG ISOLATION; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; OLEFINATION; PSEUDODISTOMA CRUCIGASTER; STEREOCHEMISTRY; SWERN OXIDATION; UTERINE CERVIX CANCER;

CHELATION CONTROLLED GRIGNARD ADDITION; CRUCIGASTERIN A; CYTOTOXICITY; JULIA OLEFINATION; TOTAL SYNTHESIS;

AMINO ALCOHOLS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; HELA CELLS; HUMANS; MCF-7 CELLS; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84882623692 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2013.07.007 Document Type: Article

Times cited : (6)

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