3D QSAR and docking studies of various amido and benzyl-substituted 3-amino-4-(2-cyanopyrrolidide)pyrrolidinyl analogs as DPP-IV inhibitors

Protein and Peptide Letters

Volumn 20, Issue 9, 2013, Pages 1066-1078

  Agrawal, Ritesh ^a   Jain, Pratima ^a   Dikshit, Subodh Narayan ^a   Jain, Sourabh ^b  

^a GOVERNMENT SCIENCE COLLEGE   (India)

^b UNIVERSITY INSTITUTE OF TECHNOLOGY   (India)

Author keywords

3 amino 4 (2 cyanopyrrolidide)pyrrolidinyl analogs; Docking; DPP IV inhibitors; Mestro; Optimum polarized ligand simulation 2005 (OPLS 2005); Pharmacophore; PHASE; QSAR; Schrodinger

Indexed keywords

3 AMINO 4 (2 CYANOPYRROLIDIDE)PYRROLIDINYL DERIVATIVE; ALOGLIPTIN; CARMEGLIPTIN; DIPEPTIDYL PEPTIDASE IV INHIBITOR; DUTOGLIPTIN; LINAGLIPTIN; MELOGLIPTIN; SAXAGLIPTIN; SITAGLIPTIN; UNCLASSIFIED DRUG; VILDAGLIPTIN;

ARTICLE; CONTROLLED STUDY; DRUG STRUCTURE; HYDROGEN BOND; HYDROPHOBICITY; LIMIT OF QUANTITATION; LIPOPHILICITY; MOLECULAR DOCKING; MOLECULAR INTERACTION; PHARMACOPHORE; QUANTITATIVE STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; VALIDATION PROCESS;

EID: 84882408604     PISSN: 09298665     EISSN: None     Source Type: Journal    
DOI: 10.2174/0929866511320090013     Document Type: Article

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