Decreased cortical representation of genital somatosensory field after childhood sexual abuse

American Journal of Psychiatry

Volumn 170, Issue 6, 2013, Pages 616-623

  Heim, Christine M ^a   Mayberg, Helen S ^a   Mletzko, Tanja ^a   Nemeroff, Charles B ^a   Pruessner, Jens C ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ANTERIOR CINGULATE; BRAIN REGION; CHILD SEXUAL ABUSE; CLITORIS; CONFERENCE PAPER; CORTICAL THICKNESS (BRAIN); EMOTIONAL ABUSE; FEMALE; HUMAN; HUMAN EXPERIMENT; LEFT HEMISPHERE; MOTOR CORTEX; MOUTH; NERVE CELL PLASTICITY; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; ONSET AGE; PARAHIPPOCAMPAL GYRUS; PERCEPTION; POSTERIOR CINGULATE; PRECUNEUS; PRIORITY JOURNAL; SELF CONCEPT; SELF EVALUATION; SEXUAL DYSFUNCTION; SOMATOSENSORY CORTEX; SOMATOSENSORY STIMULATION; STIMULUS RESPONSE; ADOLESCENT; ARTICLE; CHILD; CHILD ABUSE; FEMALE GENITAL SYSTEM; MIDDLE AGED; PATHOLOGY; PATHOPHYSIOLOGY; PSYCHOLOGICAL ASPECT; QUESTIONNAIRE;

ADOLESCENT; ADULT; CHILD; CHILD ABUSE; CHILD ABUSE, SEXUAL; FEMALE; GENITALIA, FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MIDDLE AGED; QUESTIONNAIRES; SELF CONCEPT; SEXUAL DYSFUNCTION, PHYSIOLOGICAL; SOMATOSENSORY CORTEX; YOUNG ADULT;

EID: 84882287304     PISSN: 0002953X     EISSN: 15357228     Source Type: Journal    
DOI: 10.1176/appi.ajp.2013.12070950     Document Type: Conference Paper

References (42)

1. Scott KM, Smith DR, Ellis PM: Prospectively ascertained child maltreatment and its association with DSM-IV mental disorders in young adults. Arch Gen Psychiatry 2010; 67: 712-719
2. Shonkoff JP, Garner AS; Committee on Psychosocial Aspects of Child and Family Health; Committee on Early Childhood, Adoption, and Dependent Care; Section on Developmental and Behavioral Pediatrics: The lifelong effects of early childhood adversity and toxic stress. Pediatrics 2012; 129:e232-e246
3. Paras ML, Murad MH, Chen LP, Goranson EN, Sattler AL, Colbenson KM, Elamin MB, Seime RJ, Prokop LJ, Zirakzadeh A: Sexual abuse and lifetime diagnosis of somatic disorders: a systematic review and meta-analysis. JAMA 2009; 302: 550-561
4. American College of Obstetricians and Gynecologists; Committee on Health Care for Underserved Women: Committee opinion no 498: adult manifestations of childhood sexual abuse. Obstet Gynecol 2011; 118: 392-395
5. Elbert T, Rockstroh B: Reorganization of human cerebral cortex: the range of changes following use and injury. Neuroscientist 2004; 10: 129-141
6. Maguire EA, Gadian DG, Johnsrude IS, Good CD, Ashburner J, Frackowiak RS, Frith CD: Navigation-related structural change in the hippocampi of taxi drivers. Proc Natl Acad Sci USA 2000; 97: 4398-4403
7. Flor H, Elbert T, Knecht S, Wienbruch C, Pantev C, Birbaumer N, Larbig W, Taub E: Phantom-limb pain as a perceptual correlate of cortical reorganization following arm amputation. Nature 1995; 375: 482-484
8. Elbert T, Flor H, Birbaumer N, Knecht S, Hampson S, Larbig W, Taub E: Extensive reorganization of the somatosensory cortex in adult humans after nervous system injury. Neuroreport 1994; 5: 2593-2597
9. Wiesel TN, Hubel DH: Single-cell responses in striate cortex of kittens deprived of vision in one eye. J Neurophysiol 1963; 26: 1003-1017
10. Elbert T, Pantev C, Wienbruch C, Rockstroh B, Taub E: Increased cortical representation of the fingers of the left hand in string players. Science 1995; 270: 305-307
11. Bernstein DP, Stein JA, Newcomb MD, Walker E, Pogge D, Ahluvalia T, Stokes J, Handelsman L, Medrano M, Desmond D, Zule W: Development and validation of a brief screening version of the Childhood Trauma Questionnaire. Child Abuse Negl 2003; 27: 169-190
12. Bremner JD, Vermetten E, Mazure CM: Development and preliminary psychometric properties of an instrument for the measurement of childhood trauma: the Early Trauma Inventory. Depress Anxiety 2000; 12: 1-12
13. First MB, Spitzer RL, Gibbon M, Williams JB: Structured Clinical Interview forDSM-IV-TR Axis I Disorders, Research Version.NewYork, Biometrics Research, New York State Psychiatric Institute, 2002
14. Lerch JP, Evans AC: Cortical thickness analysis examined through power analysis and a population simulation. Neuroimage 2005; 24: 163-173
15. Lerch JP, Pruessner JC, Zijdenbos A, Hampel H, Teipel SJ, Evans AC: Focal decline of cortical thickness in Alzheimer's disease identified by computational neuroanatomy. Cereb Cortex 2005; 15: 995-1001
16. Lyttelton O, Boucher M, Robbins S, Evans AC: An unbiased iterative group registration template for cortical surface analysis. Neuroimage 2007; 34: 1535-1544
17. Sled JG, Zijdenbos AP, Evans AC: A nonparametric method for automatic correction of intensity nonuniformity in MRI data. IEEE Trans Med Imaging 1998; 17: 87-97
18. Collins DL, Neelin P, Peters TM, Evans AC: Automatic 3D intersubject registration of MR volumetric data in standardized Talairach space. J Comput Assist Tomogr 1994; 18: 192-205
19. Zijdenbos AP, Forghani R, Evans AC: Automatic "pipeline" analysis of 3-D MRI data for clinical trials: application to multiple sclerosis. IEEE Trans Med Imaging 2002; 21: 1280-1291
20. MacDonald D, Kabani N, Avis D, Evans AC: Automated 3-D extraction of inner and outer surfaces of cerebral cortex from MRI. Neuroimage 2000; 12: 340-356
21. Genovese CR, Lazar NA, Nichols T: Thresholding of statistical maps in functional neuroimaging using the false discovery rate. Neuroimage 2002; 15: 870-878
22. Michels L, Mehnert U, Boy S, Schurch B, Kollias S: The somatosensory representation of the human clitoris: an fMRI study. Neuroimage 2010; 49: 177-184
23. Kell CA, von Kriegstein K, Rösler A, Kleinschmidt A, Laufs H: The sensory cortical representation of the human penis: revisiting somatotopy in the male homunculus. J Neurosci 2005; 25: 5984-5987
24. Mohanty A, Engels AS, Herrington JD, Heller W, Ho MH, Banich MT, Webb AG, Warren SL, Miller GA: Differential engagement of anterior cingulate cortex subdivisions for cognitive and emotional function. Psychophysiology 2007; 44: 343-351
25. Lou HC, Luber B, Stanford A, Lisanby SH: Self-specific processing in the default network: a single-pulse TMS study. Exp Brain Res 2010; 207: 27-38
26. Kjaer TW, Nowak M, Lou HC: Reflective self-awareness and conscious states: PET evidence for a common midline parietofrontal core. Neuroimage 2002; 17: 1080-1086
27. Guedj E, Bettus G, Barbeau EJ, Liégeois-Chauvel C, Confort- Gouny S, Bartolomei F, Chauvel P, Cozzone PJ, Ranjeva JP, Guye M: Hyperactivation of parahippocampal region and fusiform gyrus associated with successful encoding in medial temporal lobe epilepsy. Epilepsia 2011; 52: 1100-1109
28. Luck D, Danion JM, Marrer C, Pham BT, Gounot D, Foucher J: The right parahippocampal gyrus contributes to the formation and maintenance of bound information in working memory. Brain Cogn 2010; 72: 255-263
29. Chu JA, Frey LM, Ganzel BL, Matthews JA: Memories of childhood abuse: dissociation, amnesia, and corroboration. Am J Psychiatry 1999; 156: 749-755
30. Mayer AR, Hanlon FM, Franco AR, Teshiba TM, Thoma RJ, Clark VP, Canive JM: The neural networks underlying auditory sensory gating. Neuroimage 2009; 44: 182-189
31. Melzack R, Wall PD: Pain mechanisms: a new theory. Science 1965; 150: 971-979
32. Andersen SL: Trajectories of brain development: point of vulnerability or window of opportunity? Neurosci Biobehav Rev 2003; 27: 3-18
33. Hofer SB, Mrsic-Flogel TD, Bonhoeffer T, Hübener M: Experience leaves a lasting structural trace in cortical circuits. Nature 2009; 457: 313-317
34. Bushnell MC, Duncan GH, Hofbauer RK, Ha B, Chen JI, Carrier B: Pain perception: is there a role for primary somatosensory cortex? Proc Natl Acad Sci USA 1999; 96: 7705-7709
35. Jones AK, Friston K, Frackowiak RS: Localization of responses to pain in human cerebral cortex. Science 1992; 255: 215-216
36. Tommerdahl M, Delemos KA, Vierck CJ Jr, Favorov OV, Whitsel BL: Anterior parietal cortical response to tactile and skinheating stimuli applied to the same skin site. J Neurophysiol 1996; 75: 2662-2670
37. Apkarian AV, Stea RA, Manglos SH, Szeverenyi NM, King RB, Thomas FD: Persistent pain inhibits contralateral somatosensory cortical activity in humans. Neurosci Lett 1992; 140: 141-147
38. Feldman DE: Synaptic mechanisms for plasticity in neocortex. Annu Rev Neurosci 2009; 32: 33-55
39. Grant JA, Courtemanche J, Duerden EG, Duncan GH, Rainville P: Cortical thickness and pain sensitivity in zen meditators. Emotion 2010; 10: 43-53
40. Treadway MT, Grant MM, Ding Z, Hollon SD, Gore JC, Shelton RC: Early adverse events, HPA activity and rostral anterior cingulate volume in MDD. PLoS ONE 2009; 4:e4887
41. Dannlowski U, Stuhrmann A, Beutelmann V, Zwanzger P, Lenzen T, Grotegerd D, Domschke K, Hohoff C, Ohrmann P, Bauer J, Lindner C, Postert C, Konrad C, Arolt V, Heindel W, Suslow T, Kugel H: Limbic scars: long-term consequences of childhood maltreatment revealed by functional and structural magnetic resonance imaging. Biol Psychiatry 2012; 71: 286-293
42. Hardt J, Rutter M: Validity of adult retrospective reports of adverse childhood experiences: review of the evidence. J Child Psychol Psychiatry 2004; 45: 260-273