What is going on with my samples? A general approach to parallelism assessment and data interpretation for biomarker ligand-binding assays

Bioanalysis

Volumn 5, Issue 16, 2013, Pages 1941-1943

  Ciotti, Shawn ^a   Purushothama, Shobha ^a   Ray, Soma ^a  

^a BIOGEN   (United States)

Author keywords

biomarker method development; dilutional linearity; parallelism assessment; selectivity

Indexed keywords

BIOLOGICAL MARKER;

ANALYTIC METHOD; ANALYTICAL PARAMETERS; ASSAY; DATA ANALYSIS; DILUTION; DILUTIONAL LINEARITY; EDITORIAL; LIGAND BINDING; PARALLELISM; PROTEIN DETERMINATION; QUANTITATIVE ANALYSIS; SAMPLE; SENSITIVITY ANALYSIS;

BINDING SITES; BIOLOGICAL ASSAY; BIOLOGICAL MARKERS; INDICATOR DILUTION TECHNIQUES; LIGANDS;

EID: 84882286058     PISSN: 17576180     EISSN: 17576199     Source Type: Journal    
DOI: 10.4155/bio.13.174     Document Type: Editorial

References (2)

1. Valentin MA, Ma S, Zhao A, Legay F, Avrameas A. Validation of immunoassay for protein biomarkers: Bioanalytical study plan implementation to support pre-clinical and clinical studies. J. Pharm. Biomed. Anal. 55(5), 869-877 (2011
2. Lee JW, Devanarayan V, Barrett YC et al. Fit-for-purpose method development and validation for successful biomarker measurement. Pharm. Res. 23(2), 312-328 (2006